Abstract: A fluid control system for use with a patient support apparatus is moveable from a first height to a second height. The system includes a lift arm and a substantially upright cylinder. A first end of the lift arm is pivotably coupled to a base member and a second end of the lift arm is coupled to a chair structure. The cylinder assembly has a base portion and an extendable member configured to contact and support the lift arm. The cylinder assembly includes a bypass valve having a first end in fluid contact with an upper reservoir and a second end in fluid contact with a lower reservoir.
Abstract: Methods, apparatus, and systems for performing fault diagnosis are disclosed herein. In certain disclosed embodiments, methods for diagnosing faults from compressed test responses are provided. For example, in one exemplary embodiment, a circuit description of an at least partially scan-based circuit-under-test and a compactor for compacting test responses captured in the circuit-under-test is received. A transformation function performed by the compactor to the test responses captured in the circuit-under-test is determined. A diagnostic procedure for evaluating uncompressed test responses is modified into a modified diagnostic procedure that incorporates the transformation function therein. Computer-readable media comprising computer-executable instructions for causing a computer to perform any of the disclosed methods are also provided.
Abstract: The level of an audio signal can be compressed by receiving an input audio signal, determining a measure of loudness of the signal using a perceptually derived filter, determining a target gain amount, determining a current gain amount using piecewise linear attack/release logic, and producing an output audio signal by adjusting the input audio signal by the current gain amount. An audio compression filter for compressing the level of audio can comprise a loudness measuring module configured to determine a measure of loudness using a perceptually derived filter, and a compression module configured to determine a target gain amount, determine a current gain amount using piecewise linear attack/release logic, and adjust an input audio signal by the current gain amount. Audio level compression can be implemented using integer calculations.
Type:
Grant
Filed:
November 6, 2007
Date of Patent:
October 30, 2012
Assignee:
Microsoft Corporation
Inventors:
Serge Smirnov, James D. Johnston, Chris Messer
Abstract: The present invention relates to a method for quantifying protein tyrosine phosphatase (referred as PTP hereinafter) in biosamples, precisely a diagnostic method for disease by quantifying PTP using mass spectrometry and profiling of comparative PTP levels. By quantifying PTP in biosamples and profiling thereof according to the method of the present invention, disease can be diagnosed and diverse disease conditions and health conditions can be confirmed via profiling.
Type:
Grant
Filed:
August 5, 2008
Date of Patent:
October 30, 2012
Assignee:
Korea Research Institute of Bioscience and Biotechnology
Inventors:
Seong Eon Ryu, Dae Gwin Jeong, Tae Sung Yoon, Jeong Hee Moon, Seok-II Hong, Young Joon Hong
Abstract: This invention relates to a process for producing a Simian Immunodeficiency Virus (SIV) encoding a heterologous gene, which process comprises infecting a host cell with a first vector which is capable of producing SIV capsid and a second vector comprising a Human Immunodeficiency Virus type 2 (HIV-2) packaging signal sufficient to package the second vector in the SIV capsid and a heterologous gene capable of being expressed by the vector; and culturing the host cell.
Type:
Grant
Filed:
August 9, 2004
Date of Patent:
October 30, 2012
Assignee:
Cambridge Enterprise Limited
Inventors:
Andrew Michael Lindsay Lever, Padraig Michael Strappe
Abstract: Disclosed below are representative embodiments of methods, apparatus, and systems used to generate test patterns for testing integrated circuits. Embodiments of the disclosed technology can be used to provide a low power test scheme and can be integrated with a variety of compression hardware architectures (e.g., an embedded deterministic test (“EDT”) environment). Certain embodiments of the disclosed technology can reduce the switching rates, and thus the power dissipation, in scan chains with no hardware modification. Other embodiments use specialized decompression hardware and compression techniques to achieve low power testing.
Type:
Grant
Filed:
September 2, 2011
Date of Patent:
October 30, 2012
Assignee:
Mentor Graphics Corporation
Inventors:
Janusz Rajski, Grzegorz Mrugalski, Dariusz Czysz, Jerzy Tyszer
Abstract: An illumination optical apparatus which constantly controls a plurality of polarization states with high accuracy. An illumination optical system, which illuminates a pattern surface of a mask with illumination light, includes a polarization optical system and a depolarizer. The polarization optical system includes a half wavelength plate and PBS, which varies a polarization state of the illumination light to form a linear polarization state having a predetermined polarization direction. The depolarizer is arranged toward the mask from the polarization optical system and varies the polarization state of the illumination light emitted from the polarization optical system.
Abstract: The invention encompasses compounds having formula I and the compositions and methods using these compounds in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases, particularly JAK3, are therapeutically useful.
Type:
Grant
Filed:
October 11, 2010
Date of Patent:
October 30, 2012
Assignee:
Rigel Pharmaceuticals, Inc.
Inventors:
Hui Li, Vanessa Taylor, Somasekhar Bhamidipati, John Ramphal, Kin Tso, Arvinder Sran, Holger Keim, Vadim Markovtsov, David Carroll, Sambaiah Thota, Ankush Argade, Jeffrey Wayne Clough, Rajinder Singh, Robin Cooper
Abstract: We disclose growth hormone [GH] fusion proteins that have increased in vivo stability and activity; nucleic acid molecules encoding said proteins and methods of treatment of growth hormone deficiency that use said fusion proteins. The GH fusion proteins comprise human GH covalently linked to the extracellular domain of Growth Hormone Receptor [GHR] either as a direct in-frame translational fusion or via a flexible peptide linker. The GH/GHR fusion proteins have exceptional pharmacokinetics and are potent growth hormone receptor agonists. The GH/GHR fusion proteins form head to tail dimers.
Type:
Grant
Filed:
July 16, 2008
Date of Patent:
October 23, 2012
Assignee:
Asterion Limited
Inventors:
Richard Ross, Peter Artymiuk, Jon Sayers
Abstract: A process is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel, in particular, the semi-synthesis of protected taxane intermediate in a one pot reaction of protecting the C-7 and C-10 positions and attaching a side chain at the C-13 position and subsequently deprotecting the group to form paclitaxel or docetaxel, and taxane intermediates.
Abstract: Fatty acid amide hydrolase (FAAH) is an enzyme responsible for the degradation of oleamide (an endogenous sleep-inducing lipid) and anandamide (an endogenous ligand for cannabinoid receptors). Disclosed herein are potent inhibitors of FAAH and methods for their use for treating a variety of disorder, including hypertension and cardiac hypertrophy.
Type:
Grant
Filed:
April 6, 2010
Date of Patent:
October 23, 2012
Assignee:
The United States of America, as represented by the Secretary, Department of Health and Human Services
Abstract: A device for imaging a tissue culture comprises a chamber for housing a tissue to be cultured and imaged. The chamber comprises a transparent window. The device also includes a platform facing the window. Micro-needles are mounted on the platform and are connected for fluid communication with a fluid source. The platform and the window are magnetically biased toward each other to press the micro-needles into a tissue sandwiched between the window and platform for injecting a fluid into the tissue. One or more spacers are placed between the platform and the window for preventing over-compression of the tissue by the platform and the window. During use, a fluid is supplied to the tissue through the needles from the fluid source and the tissue is imaged through the window of the chamber.
Type:
Grant
Filed:
June 26, 2008
Date of Patent:
October 23, 2012
Assignee:
Agency for Science, Technology and Research
Inventors:
Hanry Yu, Yuet Mei Khong, Hwa Liang Leo
Abstract: The quality and robustness of audio echo cancellation is enhanced by selectively applying glitch recovery processes based on a quality measurement of the relative offset between capture and render audio streams. For example, large and small glitch detection is enabled for low relative offset variance; large glitch detection is enabled in a medium range of relative offset variance; and neither enabled at high variance. Further, a fast glitch recovery process suspends updating the adaptive filter coefficients of the audio echo cancellation while buffers are re-aligned to recover from the glitch, so as to avoid resetting the adaptive filter. When clock drift exists between capture and render audio streams, a multi-step compensation method is applied to improve AEC output quality in case the drifting rate is low; and a resampler is used to compensate the drift in case the drifting rate is high. An anti-clipping process detects clipping of the signals, and also suspends adaptive filter updating during clipping.
Abstract: A method for prognosing osteoporosis phenotypes or estimating osteoporosis quantitative traits comprising determining outcomes for selected SNP variables and clinical variables. Products and methods for genotyping multiple osteoporosis associated genetic variations.
Abstract: A system and method for generating a migration plan for migrating data from a first electronic medium to a second electronic medium is provided. The system comprises a migration readiness assessment module for determining a migration recommendation; an effort estimation module for determining a total effort required for migrating data from a first electronic medium to a second electronic medium; and a migration plan generator module for generating a migration plan based on the determined migration recommendation and the total estimated effort.
Abstract: A golf club head with an increased moment of inertia (MOI) about the X axis and the Z axis. Generally, the MOI about the Z axis is at least about 4400 g·cm2 and the MOI about the X axis is at least about 2500 g·cm2. The radius of the bulge of the club face is increased while the radius of the roll is reduced to compensate for the gear effect produced by the increased MOIs. The bulge curvature is generally between about 0.016 cm?1 and about 0.028 cm?1, and the roll curvature is between about 0.033 cm?1 and about 0.066 cm?1. The roll curvature is greater than the bulge curvature.
Type:
Grant
Filed:
April 16, 2012
Date of Patent:
October 23, 2012
Assignee:
Taylor Made Golf Company, Inc.
Inventors:
Mark Vincent Greaney, Brandon Woolley, Ian Wright, Todd P. Beach
Abstract: The coded block parameters used to code blocks of image samples into structures called macroblocks are compressed more efficiently by exploiting the correlation between chrominance and luminance blocks in each macroblock. In particular, the coded block pattern for chrominance and luminance are combined into a single parameter for the macroblock and jointly coded with a single variable length code. To further enhance coding efficiency, the spatial coherence of coded block patterns can be exploited by using spatial prediction to compute predicted values for coded block pattern parameters.
Abstract: A method is disclosed for reversing fixation-induced cross-linking in tissue specimens that have been preserved for histological examination. The method involves placing the fixed tissue in a liquid under elevated temperature and pressure conditions that are sufficient to reverse the fixation-induced cross-linking, restore antigenicity to proteins, and permit improved molecular and proteomic analysis of the preserved tissue specimen. Methods are also disclosed for processing tissues for histological examination under elevated pressure conditions that enhance the perfusion of liquid reagents into the tissue and reduce overall processing times.
Type:
Grant
Filed:
December 3, 2009
Date of Patent:
October 16, 2012
Assignees:
The United States of America as Represented by the Department of Veterans Affairs, The United States of America as Represented by the Secretary of Defense on behalf of the Armed Forces Institute of Pathology, American Registry of Pathology
Inventors:
Timothy J. O'Leary, Jeffrey T. Mason, Carol B. Fowler, Robert E. Cunningham
Abstract: In a process of forming a hydrogel from a mixture comprising hydrogen peroxide (H2O2), horseradish peroxidase (HRP), and a polymer comprising a crosslinkable phenol group, the gelation rate in the solution and the crosslinking density in the hydrogel can be independently adjusted or controlled by selection of the molarity of H2O2 and concentration of HRP in the solution when the molarity of H2O2 is limited to be within a range and the concentration of HRP is limited to be above a threshold. A method for determining the range and threshold is disclosed. The hydrogel may be used to grow cells, in which case, the molarity of H2O2 may be selected to affect the differentiation or growth rate of the cells in the hydrogel.
Type:
Grant
Filed:
August 20, 2009
Date of Patent:
October 16, 2012
Assignee:
Agency for Science, Technology and Research
Inventors:
Motoichi Kurisawa, Li Shan Wang, Joo Eun Chung, Fan Lee
Abstract: A new and distinct cultivar of Hemerocallis plant characterized by striking variegated leaves combined with the beautiful and large flowers of Hemerocallis ‘Kate Carpenter’.
Type:
Grant
Filed:
April 12, 2010
Date of Patent:
October 30, 2012
Inventors:
Steven Michael Brigham, Donna Gunderson Brigham