Abstract: Nucleic acids encoding mammalian, e.g., rodent, IL-1?, IL-1?, purified IL-1? and IL-1? proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
Type:
Grant
Filed:
January 25, 2001
Date of Patent:
April 17, 2007
Assignee:
Schering Corporation
Inventors:
Joseph A. Hedrick, Theodore R. Sana, J. Fernando Bazan, Robert A. Kastelein
Abstract: Nucleic acids encoding mammalian, e.g., primate or rodent, genes, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
Abstract: Nucleic acids encoding various proteases, from a mammal, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
Type:
Grant
Filed:
January 22, 2003
Date of Patent:
August 23, 2005
Assignee:
Schering Corporation
Inventors:
Christopher G. Mueller, Serge J. E. Lebecque, Yong-Jun Liu, Lynette M. Dowling, Constance F. Huffine, Daniel M. Gorman
Abstract: The invention provided herein relates generally to purified genes encoding mammalian cytokines as well as reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding these molecules. In particular, the novel cytokine, IL-B30, is provided herein as well as methods and kits for the detection of the expression of IL-B30 polynucleotides.
Abstract: Purified genes encoding cytokines from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using the reagents and diagnostic kits are also provided.