Patents Represented by Attorney M. C. Sudol
  • Patent number: 4425337
    Abstract: A method and drug form enhancing the rate of absorption of a rectally administered drug from the rectal compartment into the blood stream of a warm blooded animal. The method includes the steps of preparing a drug form capable of being rectally administered. The drug form comprises a therapeutically effective unit dosage amount of a selected drug of the type which is capable of being absorbed into the blood stream from the rectal compartment and phenothiazines or salts thereof being present in the drug form in a sufficient amount to be effective in enhancing the drug absorption rate, when rectally administering the drug form to warm blooded animals.
    Type: Grant
    Filed: December 30, 1981
    Date of Patent: January 10, 1984
    Assignee: Merck & Co., Inc.
    Inventors: Jose Alexander, Joseph A. Fix
  • Patent number: 4412994
    Abstract: Novel prodrug forms of known non-steroidal anti-inflammatory agents are disclosed, said prodrugs having the structural formula ##STR1##
    Type: Grant
    Filed: May 28, 1982
    Date of Patent: November 1, 1983
    Assignee: INTERx Research Corporation
    Inventors: Kenneth B. Sloan, Roy Little
  • Patent number: 4406896
    Abstract: A method and drug form for enhancing the rate of absorption of a rectally administered drug from the rectal compartment into the blood stream of a warm blooded animal. The method includes the steps of preparing a .beta.-lactam drug form capable of being rectally administered. The drug form comprises a therapeutically effective unit dosage amount of a selected drug of the type which is capable of being absorbed into the blood stream from the rectal compartment and hydroxy aryl or hydroxy aralkyl acids or salts, amides or esters thereof, the hydroxy aryl or hydroxy aralkyl acids or salts, amides or esters thereof being present in the drug form in a sufficient amount to be effective in enhancing the drug absorption rate, when rectally administering the drug form to warm blooded animals.
    Type: Grant
    Filed: June 25, 1981
    Date of Patent: September 27, 1983
    Assignee: Merck & Co., Inc.
    Inventors: Takeru Higuchi, Toshiaki Nishihata, Howard J. Rytting
  • Patent number: 4291050
    Abstract: This invention relates to a new class of chemical compounds which can be described generally as 6,7-disubstituted-2 or 2,2-substituted-5-substituted-1-indanones. These compounds are effective diuretic and saluretic agents.
    Type: Grant
    Filed: June 21, 1979
    Date of Patent: September 22, 1981
    Assignee: Merck & Co., Inc.
    Inventors: Otto W. Woltersdorf, Jr., Edward J. Cragoe, Jr.