Abstract: This invention relates to silicon compositions particularly useful for the production of anti-fouling varnishes that can be applied to flexible or bulk supports. In particular, embodiments of the invention are directed to cross-linkable silicone composition that is cross-linkable by polyaddition and includes at least two inter-reactive polyorganosiloxane (POS) species (A) and (B) in the presence of a metal catalyst (C) in order to allow cross-linking by polyaddition; and optionally at least one particulate component (D); at least one cross-linking inhibitor (E); optionally at least one solvent (F), optionally at least one adhesion promoter (G); and optionally at least one functional additive (H) for imparting specific properties.

Abstract: A method of reducing photodegradation of a coenzyme Q10 compound when exposed to UV radiation in a composition containing said coenzyme Q10 compound comprising combining with said coenzyme Q10 compound a compound of formula (I) in an amount effective to quench singlet excited state energy from the coenzyme Q10 compound and transfer the singlet excited state energy from the coenzyme Q10 compound to the compound of formula (I), wherein one of R1 and R2 is a straight or branched chain C1-C30 alkoxy radical, and the non-alkoxy R1 or R2 is hydrogen; and R3 is a straight or branched chain C1-C30 alkyl radical, thereby photostabilizing the retinoid compound.

Abstract: Methods and compositions are provided for delivery of a polynucleotide encoding a gene of interest, typically an antigen, to a dendritic cell (DC). The virus envelope comprises a DC-SIGN specific targeting molecule. The methods and related compositions can be used to treat patients suffering from a wide range of conditions, including infection, such as HIV/AIDS, and various types of cancers.

Abstract: A semiconductor device comprises insulating layer including damascene patterns and formed over a semiconductor substrate, conductive line formed higher than the insulating layer within the respective damascene patterns, and interference-prevention grooves formed within the damascene patterns between sidewalls of the conductive line and the insulating layer.

Abstract: A coupling conductor for a YIG filter or YIG oscillator, which may be produced from a metallic foil by eroding, laser cutting and/or etching of a metallic foil. The coupling conductor includes at least one curved section, which at least partially surrounds a YIG element and at least one conductor section.

Abstract: The invention is directed to a method of inhibiting bone resorption. The method comprises administering to a human an amount of sclerostin inhibitor that reduces a bone resorption marker level for at least 2 weeks. The invention also provides a method of monitoring anti-sclerostin therapy comprising measuring one or more bone resorption marker levels, administering a sclerostin binding agent, then measuring the bone resorption marker levels. Also provided is a method of increasing bone mineral density; a method of ameliorating the effects of an osteoclast-related disorder; a method of treating a bone-related disorder by maintaining bone density; and a method of treating a bone-related disorder in a human suffering from or at risk of hypocalcemia or hypercalcemia, a human in which treatment with a parathyroid hormone or analog thereof is contraindicated, or a human in which treatment with a bisphosphonate is contraindicated.

Abstract: A damping and shock absorbing method and apparatus for permanent or non-permanent use in the human body and having a shape memory alloy material cycled through stress-strain hysteresis to dissipate energy for effective damping. A sufficiently high pre-stress is applied to the damping element(s) to ensure that the damping working range is within the superelastic cycle. The damping apparatus can work in tension or compression or both in tension and compression. Moreover, damping elements from a shape memory alloy can also work in flexion and extension as well in rotation. The damping apparatus can have a stroke and force suitable for use in the human body by the design, the structure and the chemical composition of the shape memory alloy and their pre-set properties, such as plateau stresses of the superelastic cycle depend on the ambient temperature, the force of damping elements can also be changed in-situ by changing the temperature of the damping elements.

Abstract: A process for producing water-absorbing polymer particles, wherein a polymer gel is removed from a polymerization reactor, stored intermediately as a particulate polymer gel in a delay vessel, removed by means of a first conveying device at the lower end of the delay vessel and dried, the intermediately stored particulate polymer gel being conveyed within the delay vessel by means of at least one second conveying device above the first conveying device in the direction of the first conveying device.

Abstract: A system for driving an electric handpiece in response to a pneumatic control signal may provide for fast interchange of handpieces, self-calibration and wide dynamic range of operation with precise speed control. The system may be incorporated into virtually any dental treatment center using traditional pneumatic drive handpieces, and a conversion kit may facilitate such conversion. The system may provide not only for controlling the speed and torque of a tool coupled to an electric drive handpiece responsive to a pneumatic control signal, it may also provide for coupling cooling air and treatment media, such as air and/or water to the handpiece. Coupling of a handpiece to an operating base of the system, including coupling of media lines and electrical connections may be made with a simple press and twist action using quick connection structure.

Abstract: The a method of treating elevated blood levels of iPTH by increasing or maintaining blood concentrations of both 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D in a patient by administering, as necessary, both Vitamin D repletion and Vitamin D hormone replacement therapies, is disclosed. The blood concentrations of 25-hydroxyvitamin D are increased to and maintained at or above 30 ng/mL, and blood concentrations of 1,25-dihydroxyvitamin D are increased to or maintained within a patient's normal historical physiological range for 1,25-dihydroxyvitamin D without causing substantially increased risk of hypercalcemia, hyperphosphatemia or over suppression of plasma iPTH in the patient. The blood levels of 25-hydroxyvitamin D are maintained at or above 30 ng/mL between doses of Vitamin D repletion therapies, and the blood levels of 1,25-dihydroxyvitamin D are maintained in the patient's normal historical physiological range between doses of Vitamin D hormone replacement therapies.

Abstract: A liquid delivery apparatus for the intrathecal delivery of one or more medications to a patient is disclosed. The liquid delivery apparatus generally includes a liquid reservoir, a liquid metering unit fluidly connected to the liquid reservoir, and a catheter delivery tube fluidly connected to the liquid metering unit. Preferably, the liquid delivery apparatus includes two or more liquid reservoirs. In various embodiments, the liquid reservoir includes a deformable balloon and a compressive sleeve spring as a pressure source, the liquid metering unit is a piezoelectrically actuated microvalve, and/or diagnostic sensors are included in the apparatus. The disclosed apparatus are compact, volume-efficient, energy-efficient, capable of delivering accurate fluid volumes, and address problems associated with multi-medication therapies. Methods of operating the liquid delivery apparatus are also disclosed.

Abstract: A semiconductor device includes a NMOS transistor of a peripheral circuit region. The NMOS transistor is formed over a relaxed silicon germanium layer and a silicon layer to have a tensile strain structure, thereby increasing electron mobility of a channel region in operation of the device. The semiconductor device may include a second active region including a first silicon layer connected to a first active region of a semiconductor substrate, a second silicon layer and a relaxed silicon germanium layer formed over the first silicon layer expected to be a NMOS region, and a NMOS gate formed over the second silicon layer.

Abstract: Disclosed herein is a digital electro-optical switch (1) comprising: an electro-optical substrate (3); a Y-shaped optical waveguide (2) formed in the substrate (3) and including an input branch (4) configured to be connected to an input optical waveguide, and two output branches (5) configured to be connected to respective output optical waveguides; and electrically conductive electrodes (6, 7) formed on the substrate (3) and including an inner electrode (7) arranged between the output branches (5), substantially at a branching area of the optical waveguide (2), and two outer electrodes (6) arranged outside the output branches (5), on opposite sides of the inner electrode (7), the outer electrodes (6) being electrically operable to make the electro-optical switch (1) operative between a first switching state wherein transmission of optical energy is enhanced between the input branch (4) and a first one of the output branches (5), and substantially inhibited in a second one of the output branches (5), and a se

Abstract: A method of manufacturing a flash memory device comprises forming a gate insulating layer on a semiconductor substrate, forming silicon seed crystals on a surface of the gate insulating layer by reacting a nitrogen or oxygen atmosphere gas and a silicon source gas, forming a first layer for a floating gate over the gate insulating layer and the silicon seed crystals by increasing an amount of the silicon source gas, and forming a second layer for a floating gate on the first layer for a floating gate.

Abstract: Methods, systems, and computer-executable instructions for event synchronized reporting in an process control system are disclosed. Events may be synchronized by a synchronization parameter, whose instances of occurrence may be non-contiguous in time. Examples of synchronization parameters may include a work shift, a work group, an individual's on-duty time, a logged-on period of an individual, the execution times of a process control entity, a batch run type, and a procedure or sub-unit of a batch run. Instances of occurrence of the synchronization parameter may be recorded into a process control event database. Event synchronized reports may contain at least one synchronization value based on both the instances of occurrence of the synchronization parameter as well as historical process control data. Data from various historian databases may be accessed from process control system tools and integrated into a single report.

Abstract: A method for processing multi-phasic dispersions is provided. The method comprises providing a multi-phasic dispersion, the dispersion including dispersed and continuous phases, the dispersion comprising solid microparticles, providing a non-solvent, combining the multi-phasic dispersion and the non-solvent, and selectively effecting migration of the dispersed phase into or through the non-solvent such that the microparticles are separated from the dispersion.

Abstract: A method of fabricating a landing plug in a semiconductor memory device, which in one embodiment includes forming a landing plug contact hole on a semiconductor substrate having an impurity region to expose the impurity region; forming a landing plug by filling the landing plug contact hole with a polysilicon layer, wherein the landing plug comprises a first region, a second region, a third region, and a fourth region, wherein the first region is disposed beneath the second region and doped with a first doping concentration, the second region is disposed above the first region and below the third region and is not doped, the third region is disposed above the second region and below the fourth region and is doped with a second doping concentration that is lower than the first doping concentration, and the fourth region is disposed above the third region and is doped with a third doping concentration that is higher than the first doping concentration; and annealing the resulting product formed with the landing

Abstract: Materials and methods useful for generating highly mannosylated pseudotyped lentiviral vector particles comprising a Vpx protein are provided. More specifically, methods for generating such materials include culturing in a culture medium including kifunensine a virus packaging cell with a lentiviral vector genome including a polynucleotide encoding an exogenous antigen, a polynucleotide encoding a Sindbis E2 glycoprotein that preferentially binds dendritic cells expressing DC-SIGN, and a polynucleotide encoding a Vpx protein or a Vpr protein that retains SAMHD1-inhibiting activity, followed by isolating a pseudotyped lentiviral vector particle that preferentially binds dendritic cells expressing DC-SIGN.

Abstract: Methods for processing microparticles involve providing a composition comprising a plurality of solid microparticles and at least one non-volatile material, providing a non-solvent, and exposing the composition to the non-solvent to remove at least a portion of the non-volatile material from the composition while retaining at least the microparticles.