Patents Represented by Attorney, Agent or Law Firm Matthew Boxer
  • Patent number: 5750532
    Abstract: The disclosed invention is compounds represented by the formula ##STR1## and pharmacetically acceptable acid salts thereof, wherein each Z is independently tetiary butyl, phenyl, naphthyl or adamantyl; substituted phenyl, wherein the substituents are one or more of halogen, lower alkoxy, phenoxy, nitrile, nitro, phenylsulfonyl, loweralkyl-sulfonyl, oxazol-2-yl, lower alkanoyl, benzoyl, lower alkoxycarbonyl, lower alkyl, lower alkylthio, phenyl, phenylaminothiocarbonyl, or lower alkylaminothiocarbonyl, hydroxyiminoloweralkyl hydroxyloweralkyl or carbonyl; or 4 or 6 membered unsubstituted or substituted heterocyclic ring containing at least one nitrogen with the remaining member of the ring being at least one carbon, and optionally sulfur or oxygen,X and Y are each independently a bond, ##STR2## each Q is independently a divalent substituted or unsubstituted, straight or branched chain lower alkanediyl, lower alkanediyl-cycloalkanediyl-lower alkanediyl, lower alkenediyl, lower alkynediyl, phenylene, dihydrofura
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: May 12, 1998
    Assignee: Schering Corporation
    Inventors: Viyyoor M. Girijavallabhan, Ashit K. Ganguly, Patrick A. Pinto, Richard W. Versace
  • Patent number: 5747442
    Abstract: The present invention relates to pretreater or compositions in stick form which remove stains. The compositions contain 30 to 80 wt. % of a nonionic surfactant, 1 to about 20 wt. % of an anionic soap, and 0.1% to 10 wt. % of a hydrophobically modified polar polymer. A method of using the composition is also described.
    Type: Grant
    Filed: January 25, 1996
    Date of Patent: May 5, 1998
    Assignee: Lever Brothers Company, Division of Conopco, Inc.
    Inventors: Barbara Helen Bory, Walter Joseph Lunsmann, Dennis Stephen Murphy, Tamara Padron, Lucia Victoria Salas
  • Patent number: 5738891
    Abstract: A sterile, packed food emulsion suitable for fully cooking a host food or adding to cooked food and for imparting a golden brown au gratin coating upon cooking, and including: water; 10-65 wt % edible fat; 0.05-10.00 wt % caseinate; and 0.1-10.0 wt % browning agent, which is chosen from a group consisting of carbohydrates, proteins and mixtures thereof; wherein the emulsion has a pH of at least 5.0 and further includes at least 0.5 ppm lysophospholipoprotein as an emulsifier.
    Type: Grant
    Filed: February 21, 1996
    Date of Patent: April 14, 1998
    Assignee: Van Den Bergh Foods Company, Division of Conopco, Inc.
    Inventors: Cornelis Frederik Andreae, Philip Edward Dazo, Gijsbert Kuil, Gerardus Anthonius Matthijssen, Johannes Frederik Mulder
  • Patent number: 5739104
    Abstract: Compounds of the formula ##STR1## or pharmaceutically acceptable salts thereof wherein R.sub.1, R.sub.2, X.sub.1, X.sub.2, X.sub.3, X.sub.4, X.sub.5, X.sub.6, X.sub.7, and X.sub.8, are as set forth herein are described. These compounds are useful as agents in the treatment of fungal infections.
    Type: Grant
    Filed: April 26, 1995
    Date of Patent: April 14, 1998
    Assignee: Schering Corporation
    Inventors: Alan B. Cooper, Anil K. Saksena, Dinanath F. Rane, Edwin Jao, Viyyoor M. Ginjavallabhan, Ashit Ganguly, Jagdish J. Desai, James Wang
  • Patent number: 5710114
    Abstract: A conditioning shampoo containing an anionic surfactant, a long-chain fatty alcohol, and a cationic polyethyleneimine, has extended product stability, excellent cleansing and foaming properties, and provides excellent and improved overall conditioning to human hair, particularly superior wet and dry combing properties.
    Type: Grant
    Filed: May 29, 1996
    Date of Patent: January 20, 1998
    Assignee: Helene Curtis, Inc.
    Inventor: Daniel Raymond Pyles
  • Patent number: 5702694
    Abstract: Topical compositions for the treatment of corns, calluses and warts comprising a benzenediol or a substituted 1,2-benzenediol and a pharmaceutically acceptable carrier, are described.
    Type: Grant
    Filed: February 12, 1996
    Date of Patent: December 30, 1997
    Assignee: Schering-Plough HealthCare Products, Inc.
    Inventor: Thomas W. Chamness
  • Patent number: 5700387
    Abstract: Patent application that covers the concept of a conditioner sheet coated with a solubilised rinse conditioners comprising a fabric softening compound and a solubilising agent. The dryer sheets softens at low temperatures and is non-staining. The invention works particularly well with HEQ.
    Type: Grant
    Filed: April 6, 1995
    Date of Patent: December 23, 1997
    Assignee: Lever Brothers Company, Division of Conopco, Inc.
    Inventors: Ziya Haq, Abid Nadim Khan-Lodhi, Philip John Sams
  • Patent number: 5693815
    Abstract: Compounds of formula ##STR1## wherein Ar, W, Z, Q, R.sub.1, U, and L are as set forth herein, are described. These compounds are active as agents against HIV and inhibit renin and therefore are also active against hypertension. Similar retroviruses against which the compounds of the invention are active include the retrovirus which causes feline AIDS, and the retrovirus which causes Rous' sarcoma which is a disease of chickens.
    Type: Grant
    Filed: July 14, 1995
    Date of Patent: December 2, 1997
    Assignee: Schering Corporation
    Inventors: Frank Bennett, Viyyoor M. Girijavallabhan, Naginbhai M. Patel
  • Patent number: 5690985
    Abstract: A process of forming a liquid edible emulsion spread and the product itself is described. A tempering accelerator in an amount of from 2-10% by weight incorporated in a fat blend. The accelerator is preferably 2-elaidoyl triacylglycerol.
    Type: Grant
    Filed: October 15, 1996
    Date of Patent: November 25, 1997
    Assignee: Van Den Bergh Foods Co., Division of Conopco, Inc.
    Inventors: Johanna Antonia Van Meeteren, Leendert Hendrik Wesdorp
  • Patent number: 5686083
    Abstract: Topical compositions for the treatment of corns and calluses comprising a 4 carbon .alpha.-keto acid and a pharmaceutically acceptable carrier, are described.
    Type: Grant
    Filed: August 11, 1995
    Date of Patent: November 11, 1997
    Assignee: Schering-Plough HealthCare Products Inc.
    Inventor: Thomas W. Chamness
  • Patent number: 5667837
    Abstract: Edible plastic fat-product is provided that comprises a continuous fat phase and optionally a dispersed aqueous phase wherein the fat of the fat phase is a fat-composition comprising 20-65% liquid oil and 80-35% structuring fat and having N.sub.35 of 0-5 and N.sub.20 of 12-40, the difference between N.sub.20 and N.sub.35 being at least 12, preferably 18-30, which composition comprises 0-10% trans fatty acid residues and which comprises 10-50% not-interesterified lauric fat selected from the group consisting ofa combination of unhydrogenated and fully hydrogenated lauric fat,partially hydrogenated lauric fat,a combination thereof, anda combination of at least one thereof with other lauric fat.The choice of this lauric fat allows obtaining a big difference between N.sub.20 and N.sub.35, without using fats with a high content of trans fatty acid residues.
    Type: Grant
    Filed: May 17, 1996
    Date of Patent: September 16, 1997
    Assignee: Van den Bergh Foods Co., Division of Conopco, Inc.
    Inventors: Rowena Allison Broomhead, Hindrik Huizinga
  • Patent number: 5663361
    Abstract: A process for preparing a compound of formula I ##STR1## wherein R and R" are as described herein. Compounds of formula I are useful as intermediates in the preparation of florfenicol.
    Type: Grant
    Filed: August 19, 1996
    Date of Patent: September 2, 1997
    Assignee: Schering Corporation
    Inventors: James C. Towson, Dhiru B. Vashi
  • Patent number: 5654316
    Abstract: The invention relates to compounds of the formula ##STR1## wherein X, i, j, n, n', A, A', R.sub.2, R.sub.3, and U are as described herein. The compounds of the invention are NK.sub.1 or NK.sub.2 or NK.sub.3 receptor antagonists and as such are useful in the treatment of diseases such as asthma.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: August 5, 1997
    Assignee: Schering Corporation
    Inventors: Nicholas I. Carruthers, Cheryl A. Alaimo
  • Patent number: 5652226
    Abstract: The compound of the formula I ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, and R.sup.8 are as defined herein, are described. These compounds are antibacterial agents.
    Type: Grant
    Filed: December 22, 1995
    Date of Patent: July 29, 1997
    Assignee: Schering Corporation
    Inventors: Viyyoor M. Girijavallabhan, Anil K. Saksena, Frank Bennett, Edwin Jao, Naginbhai M. Patel, Ashit Ganguly
  • Patent number: 5618707
    Abstract: A stereoselective reduction of compound II to compound of formula I ##STR1## which comprises adding ketone substrate II to a culture broth of the Zygosaccharomyces bailii ATCC 38924, incubating the resulting mixture, and isolating a hydroxy compound of formula I, is described. The resulting compound of formula I is useful as an intermediate in the preparation of 1-(4-fluorophenyl)-3(R)-[3(S)-hydroxy-3-(4-fluorophenyl)propyl]-4(S)-(4-hy droxyphenyl)-2-azetidinone which is a serum cholesterol lowering agent. Also described is a stereoselective reduction of a compound of formula IV to compound of formula III ##STR2## using Schizosaccharomyces octosporus ATCC 2479.
    Type: Grant
    Filed: January 4, 1996
    Date of Patent: April 8, 1997
    Assignee: Schering Corporation
    Inventors: Michael J. Homann, Edward Previte
  • Patent number: 5618793
    Abstract: Compounds of the formula ##STR1## wherein R.sub.3, R.sub.4, J, K, Z, and Het are as set forth herein are described.The compounds of formula I are useful as agents in the treatment of fungal infections.
    Type: Grant
    Filed: August 1, 1995
    Date of Patent: April 8, 1997
    Assignee: Schering Corporation
    Inventors: Alan B. Cooper, Anil K. Saksena, Raymond Lovey, Viyyoor Girijavallabhan, Ashit Ganguly
  • Patent number: 5608067
    Abstract: Disclosed herein are compounds of the formula ##STR1## wherein R.sub.1, R.sub.3, R.sub.4, R.sub.11, and c are as set forth herein are described. These compounds are useful as agents for the treatment of mammals infected with herpes group virus. Certain of these compounds are useful as antitumor agents.
    Type: Grant
    Filed: April 28, 1994
    Date of Patent: March 4, 1997
    Inventors: Adriano Afonso, Joseph M. Kelly, Samuel Chackalamannil
  • Patent number: 5597821
    Abstract: The invention relates to compounds of the formulas ##STR1## wherein R.sub.1, R.sub.2, X and Z are as described herein. These compounds are useful as antitumor agents.
    Type: Grant
    Filed: December 15, 1994
    Date of Patent: January 28, 1997
    Inventors: Ronald L. Wolin, Adriano Afonso
  • Patent number: 5595998
    Abstract: The invention relates to compounds of the formulas ##STR1## wherein X, R.sub.1, R.sub.2, and R.sub.3, are as described herein. These compounds are useful as antitumor agents. Pharmaceutical compositions containing compounds of formula I are also described. Methods for treating tumors which comprise administration of compounds of formula I are also described. Processes for preparing compounds of formula I are also described.
    Type: Grant
    Filed: December 15, 1994
    Date of Patent: January 21, 1997
    Inventors: Ronald L. Wolin, Adriano Afonso, Joseph M. Kelly, F. George Njoroge
  • Patent number: 5589472
    Abstract: The invention relates to compounds of the formula ##STR1## wherein X, Y, Z, R.sub.1, R.sub.2, R.sub.4, and R.sub.5, are as described herein. These compounds are useful as agents for the treatment of inflammation, tumors and psoriasis.
    Type: Grant
    Filed: March 10, 1995
    Date of Patent: December 31, 1996
    Inventor: Susan F. Vice