Patents Represented by Attorney Max D. Hensley

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  • Method for determining endotoxin concentration
    Patent number: 4221865
    Abstract: Improvements in the sensitivity and reproducibility of nephelometric endotoxin determinations using endotoxin-activated enzyme from Limulus amebocyte lysate are achieved by contacting endotoxin-coagulated lysate with an ionic surface active suspending agent, generally a mixture of detergent and suspending agent. Instrumentation improvements further enhance results.
    Type: Grant
    Filed: October 6, 1978
    Date of Patent: September 9, 1980
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: John A. Dubczak, Marlys E. Weary
  • Method and apparatus for making novel particulate compositions
    Patent number: 4211015
    Abstract: An improved method and apparatus is disclosed for producing frozen particulate compositions from liquid feedstock. A continuous stream of liquid feedstock is passed through an orifice and into a liquid freezant without the orifice contacting the freezant. Compositions produced by this improved method have low proportions of fine and large particles, yielding particularly beneficial results in the case of quality control materials. The compositions are advantageously employed in automated weighing and filling apparatus.
    Type: Grant
    Filed: January 18, 1978
    Date of Patent: July 8, 1980
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: Thomas H. Adams, James P. Beck, Robert C. Menson
  • Antistatic method and apparatus
    Patent number: 4208132
    Abstract: Static charge accretion as a result of particle handling is prevented or reduced by contacting the particles with an ionized noble gas. Particularly beneficial results are obtained by contacting dried, particulate animal body fluid with an ionized gas while conducting sieving, blending or dispensing operations.Apparatus for contacting the ionized gas with particles so as to control static charge accumulation employs a flowthrough ionized gas, preferrably a noble gas, in which ionization takes place outside of the apparatus particle treatment region.
    Type: Grant
    Filed: July 25, 1978
    Date of Patent: June 17, 1980
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventor: Barbara E. Stevens
  • Photometric determination of protein, and of endotoxin with Limulus protein
    Patent number: 4104030
    Abstract: An optical density technique for measuring protein concentration generally, or for measuring minute traces of endotoxin in an unknown material by the clotting of Limulus lysate protein. After the clotting step, the clotted protein is separated and digested in from 0.1 to 0.4N strong alkali such as sodium hydroxide and then photometrically analyzed, for example with the Lowry test. Greatly improved stability of a quantitative endopoint is achieved under this circumstance.
    Type: Grant
    Filed: November 4, 1977
    Date of Patent: August 1, 1978
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: Robert E. Hopkins, II, Kathleen Hughes
  • Rapidly solubilized AHF composition and process for preparing same
    Patent number: 4089944
    Abstract: The rate of solubility of a freeze-dried solid composition containing therapeutic amounts of anti-hemophilic factor (AHF) is greatly increased by carrying out the solubilization in the presence of at least a critical threshold amount of a water soluble carbohydrate. The carbohydrate is incorporated into the AHF composition in sufficient quantity to provide at least 2 weight units of carbohydrate (expressed in grams) per 100 volume units of AHF solution (expressed in milliliters). This enhanced rate of solubility permits rapid treatment of hemophilic patients.
    Type: Grant
    Filed: October 5, 1976
    Date of Patent: May 16, 1978
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventor: William R. Thomas
  • Blood fractionation process using block copolymers of ethylene oxide and polyoxypropylene
    Patent number: 4073886
    Abstract: A method of separating proteinaceous and lipid materials from blood serum and plasma which comprises selective precipitation with block copolymers of ethylene oxide and polyoxypropylene polymer.
    Type: Grant
    Filed: January 30, 1973
    Date of Patent: February 14, 1978
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventor: Walter C. Kehm
  • Method and device for racking and sealing containers
    Patent number: 4040234
    Abstract: A rack assembly comprising mounting means for containers, e.g., test tubes, a lid spaced from said mounting means which cooperates with orifices in the containers, a flexible sealing sheet for sealing the orifices interposed between the lid and mounting means, and means for spacing the lid from the mounting means and for gripping the sealing sheet. Containers are inserted in the mounting means. The sheet is then placed over the containers, and the lid in turn placed over the sheet so that the sheet seals the container orifices as the containers are maintained in substantially fixed position by the mounting means. By agitating the rack assembly the containers held therein are also shaken. The rack assembly is easily re-used by stripping off and discarding the sealing sheet.
    Type: Grant
    Filed: January 14, 1976
    Date of Patent: August 9, 1977
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: Douglas P. Stockdale, Richard Mencarini, Carlton D. Deaton, Ralph M. Owen
  • Preparation of albumin by fractionation of blood plasma or serum
    Patent number: 4025500
    Abstract: A method of fractionating coagulation factor-depleted blood serum or plasma by selective precipitation with block copolymers of ethylene oxide and polyoxypropylene polymer to provide immunoglobulin preparations, albumin-containing fractions and organ perfusates.
    Type: Grant
    Filed: November 21, 1975
    Date of Patent: May 24, 1977
    Assignee: Baxter Laboratories, Inc.
    Inventors: Luis A. Garcia, Guido A. Ordonez
  • Method for removing seeds from papayas
    Patent number: 4002774
    Abstract: The blossom and stem ends of a papaya are sliced off to expose the seed cavity, and the seeds therein are blown out by a jet of fluid.
    Type: Grant
    Filed: August 20, 1975
    Date of Patent: January 11, 1977
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventor: Harvey T. Chan, Jr.
  • Production of antisera comprising fractionating plasma or serum with an ethylene oxide-polyoxypropylene block copolymer
    Patent number: 4000121
    Abstract: A process for the preparation of a stable and concentrated antiserum comprising sequentially fractionating blood plasma or serum with block copolymers of ethylene oxide and polyoxypropylene polymer at selected concentrations and pH's.
    Type: Grant
    Filed: October 7, 1974
    Date of Patent: December 28, 1976
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventor: Luis A. Garcia
  • Diagnostic reagent system
    Patent number: 3995019
    Abstract: A solid phase reagent for use in radioimmunoassay of antigens and antibodies prepared by admixing specific antibody or radiolabeled antigen with polyethylene glycol and gamma globulin in buffer at pH 4-10 and lyophilizing.
    Type: Grant
    Filed: March 4, 1975
    Date of Patent: November 30, 1976
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventor: Frederick R. Jerome
  • Stopper assembly
    Patent number: 3991896
    Abstract: A reagent tube and stopper assembly comprising in combination a cylindrical receptacle for containing a clot timing test reagent solution and a flexible stopper for closure thereof and dispensing a spherical member into said reagent solution by depressing a probe into an upper cavity in said stopper and against a thin membrane separating a lower sphere containing cavity in said stopper.
    Type: Grant
    Filed: November 27, 1974
    Date of Patent: November 16, 1976
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventor: Eduardo V. Miranda
  • Quaternary arylaminoalkyl phosphonium salts
    Patent number: 3987098
    Abstract: Novel quaternary arylaminoalkyl phosphonium salts having the formula [(ArNHCHR).sub.4 P].sup.+X.sup.-, where R is a radical selected from the group consisting of hydrogen, alkyl and aryl, Ar is aryl, and X is halogen, are prepared by the reaction of primary aromatic amines with quaternary hydroxyalkyl phosphonium salts having the formula [(HOCHR).sub.4 P].sup.+X.sup.-, where R and X are similarly defined. The compounds of this invention are useful as flame retardant for cotton, plasticizers, lubricant additives, and surface-active agents.
    Type: Grant
    Filed: December 5, 1974
    Date of Patent: October 19, 1976
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: Arlen W. Frank, George L. Drake, Jr.
  • Adjustable rotator for fluid samples
    Patent number: 3980227
    Abstract: Samples which are to be processed or analyzed in the laboratory are placed in small vials or cuvettes. Groups of cuvettes are placed in arcuate carriers, which are then mounted about the periphery of a rotator head. The rotator head has two selectable motions. It can rotate at a higher speed on a vertical axis for an automatically timed period, thereby subjecting the samples to mild centrifugal settling or sedimentation, or it can rotate at a lower speed about an inclined axis, thereby subjecting the sample to mild agitation or mixing.
    Type: Grant
    Filed: November 8, 1974
    Date of Patent: September 14, 1976
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: Michael E. Witty, Dennis F. Shine, Dennis J. Reisdorf
  • Calibrating fluid for blood cell counting and hemoglobin determination
    Patent number: 3977995
    Abstract: A calibrating fluid for automated instruments for blood cell counting and hemoglobin determination comprising a sterile solution of oxyhemoglobin or other derivative products of hemoglobin and containing latex particles.
    Type: Grant
    Filed: October 17, 1974
    Date of Patent: August 31, 1976
    Assignee: Baxter Laboratories, Inc.
    Inventors: Allan L. Louderback, Anthony J. Fontana
  • Chicken coop lifting device
    Patent number: 3976320
    Abstract: An apparatus and a process for transporting chicken coops into and out of a processing plant are disclosed. A stack of chicken coops can be lifted by the apparatus which straddles, grasps, supports, lifts, and relocates a stack or stacks into or within a poultry warehousing situation as well as out of the area, with efficiency and safety.
    Type: Grant
    Filed: August 14, 1975
    Date of Patent: August 24, 1976
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: John H. Holladay, Albert D. Shackelford
  • Mosquito larvicide
    Patent number: 3972897
    Abstract: Limonene (or alpha-pinene) is condensed with sesamol under aqueous acidic conditions to produce a mixture of two novel compounds which are useful as mosquito larvicides.
    Type: Grant
    Filed: October 30, 1975
    Date of Patent: August 3, 1976
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: Kenneth L. Stevens, Leonard Jurd
  • Process for separating DOPA from tyrosine
    Patent number: 3972918
    Abstract: Tyrosine and 3,4-dihydroxyphenylalanine (DOPA) are separated from a mixture thereof by applying the mixture to a polymer of p-vinylbenzene boronic acid, and then serially eluting the tyrosine and DOPA.
    Type: Grant
    Filed: June 28, 1974
    Date of Patent: August 3, 1976
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: William L. Stanley, Carl A. Elliger, Bock G. Chan
  • Stabilization of AHF using heparin
    Patent number: RE29698
    Abstract: A method of improving the yield of antihemophilic Factor .[.A.]. .Iadd.VIII (AHF) .Iaddend.obtained from blood plasma and plasma fractions .Iadd.by cryoprecipitation .Iaddend.comprising the addition of from 0.01 to 10 units of heparin to .Iadd.a concentrate of AHF obtained by cryoprecipitation from .Iaddend.said plasma or plasma fraction per ml. of solution thereof.
    Type: Grant
    Filed: April 6, 1976
    Date of Patent: July 11, 1978
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: Lajos F. Fekete, Stephen L. Holst
  • Method of detecting antigens or antibodies
    Patent number: RE29955
    Abstract: This disclosure concerns a solid phase method for detecting antigens or antibodies. An unknown sample is contacted with two sources of solid phase antigen. By treating each source in a particular manner it is possible to determine if the sample contains antigen or antibody.
    Type: Grant
    Filed: March 13, 1978
    Date of Patent: April 3, 1979
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: Irene Bornstein, Andreas A. Kapsalis