Abstract: The present invention relates to monoazo dyes which dye polyamide material with good light- and wet-fastness and which have the formula ##STR1## in which K is the radical of an amino- or alkoxy-benzene, amino- or alkoxy-naphthalene, naphthol, aminonaphthol, pyrazolone, aminopyrazole, indole, naphthimidazole, diphenylamine, tetrahydroquinoline or acetoacetamide and can be further substituted, R is hydrogen, halogen, C.sub.1-6 -alkyl, trifluoromethyl, carboxyl or a --SO.sub.2 --C.sub.1-6 --alkyl, --SO.sub.2 --R.sub.1, ##STR2## --CO--R.sub.4 group, in which R.sub.1 is a substituted or unsubstituted phenyl- or naphthyl-C.sub.1-4 -alkyl radical, R.sub.2 and R.sub.3 independently of one another are hydrogen or a substituted or unsubstituted C.sub.1-6 -alkyl or C.sub.5-7 -cycloalkyl radical and R.sub.4 is a substituted or unsubstituted phenyl radical, and X is hydrogen, C.sub.1-4 -alkyl, C.sub.1-4 -alkoxy or halogen, and in which R in formula (1) may not be hydrogen or chlorine if the radical --N.dbd.
Abstract: Azo dyes of the formula ##STR1## or tautomeric forms thereof, in which: Z is N or CH,X is O, NR.sub.1 or N,W is N or C,K is a coupling component,R is hydrogen, C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C.sub.4 -alkoxy, halogen, nitro, --CN, --NHR.sub.1, --NH-acyl, phenoxy, --COOH, COOR.sub.1, --CONHR.sub.1 or substituted or unsubstituted phenyl, R.sub.1 being hydrogen, substituted or unsubstituted C.sub.1 -C.sub.6 -alkyl or substituted or unsubstituted phenyl,M is H.sup..sym., Li.sup..sym., Na.sup..sym., K.sup..sym., NH.sub.4.sup..sym. or the protonated form of a C.sub.4 -C.sub.12 -trialkylamine, of a C.sub.4 -C.sub.12 -diamine or of a C.sub.2 -C.sub.12 -alkanolamine,A is a carbocyclic or nitrogen-containing aromatic radical which can be further substituted, andB is a 1,4-phenylene radical which can be further substituted.
Abstract: Dyes suitable for dyeing wool, polyamide and leather in orange, brown or olive-brown shades are disclosed, the dyes having the formula ##STR1## wherein A and D are each independently of the other a benzene or napththalene radical of a diazo component, which component carries the hydroxyl or carboxyl group in the ortho-position to the azo group;B is the radical of a coupling component which carries the group X adjacent to the azo group;X is oxygen or a radical of the formula --R--, in which R is hydrogen or C.sub.1 -C.sub.4 alkyl;Y is a radical of the formula ##STR2## in which formulae R.sup.1 and R.sup.5 are each independently of the other hydrogen or sulfo, R.sup.4 is hydrogen or nitro, R.sup.6 is hydrogen, methyl, methoxy or chlorine and R.sup.2 and R.sup.3 are each independently of the other hydrogen, halogen, nitro or sulfo;Ar.sup.1 is a benzene or napththalene radical which is unsubstituted or substituted by halogen, nitro, sulfo, C.sub.1 -C.sub.4 -alkyl or C.sub.1 -C.sub.
Type:
Grant
Filed:
December 19, 1986
Date of Patent:
October 17, 1989
Assignee:
Ciba-Geigy Corporation
Inventors:
Gerhard Back, Fabic Beffa, Ulrich Schlesinger, Alois Puntener
Abstract: The described novel pyridine derivatives are those of the general formula I ##STR1## wherein R is hydrogen, C.sub.1 -C.sub.6 -alkyl, C.sub.3 -C.sub.6 -cycloalkyl, phenyl, benzyl, phenyl substituted by C.sub.1 -C.sub.4 -alkyl, halogen, C.sub.1 -C.sub.4 -alkoxy, NO.sub.2 and/or CF.sub.3, or benzyl substituted by C.sub.1 -C.sub.4 -alkyl, halogen, C.sub.1 -C.sub.4 -alkoxy, NO.sub.2 and/or CF.sub.3,R.sub.1 and R.sub.2 independently of one another are each hydrogen, C.sub.1 -C.sub.4 -alkyl, halogen or C.sub.1 -C.sub.4 -alkoxy,R.sub.3, R.sub.4 and R.sub.5 independently of one another are each hydrogen, halogen, CF.sub.3, NO.sub.2, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy, phenyl, or phenyl substituted by C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy, halogen, NO.sub.2 and/or CF.sub.3,U and V independently of one another are each C.sub.1 -C.sub.6 -alkyl, or alkyl substituted by halogen or C.sub.1 -C.sub.4 -alkoxy, or together form one of the following alkylene bridges: ##STR2## R.sub.a is hydrogen, C.
Abstract: The invention relates to parasiticidally and insecticidally highly active compounds of formula I ##STR1## wherein R is C.sub.1 -C.sub.10 alkyl;R.sub.1 is hydrogen, a silyl group or a sugar residue; andR.sub.2 is methyl, ethyl, isopropyl or sec-butyl, and to the preparation thereof starting from suitably substituted 15-ester or 13.beta.-ester milbemycins.
Type:
Grant
Filed:
January 17, 1986
Date of Patent:
August 15, 1989
Assignee:
CIBA-GEIGY Corporation
Inventors:
Bruno Frei, Anthony C. O'Sullivan, Jean-Claude Gehret
Abstract: A process for the preparation of reactive dyes of the formula ##STR1## in which D, R and Z are as defined in greater detail in the description, which comprises subjecting 2,4,6-trifluoro-s-triazine to a condensation reaction in a strongly acid solution and in the presence of an alkali metal fluoride with an amine of the formulaH--Z (3)and then subjecting the primary condensation product obtained to a condensation reaction with an amino dye of the formula ##STR2## affords reactive dyes of the formula (1) in a high yield and a high state of purity.
Abstract: Reactive dyes of the formula ##STR1## in which (R).sub.n stands for n substituents R which, independently of each other, can be C.sub.1-4 -alkyl, C.sub.1-4 -alkoxy, halogen, carboxyl, carbamoyl, N-C.sub.1-4 -alkylcarbamoyl, N,N-di-C.sub.1-4 -alkylcarbamoyl, C.sub.1-4 -alkylsulfonyl, sulfamoyl, N-C.sub.1-4 -alkylsulfamoyl or N,N-di-C.sub.1-4 -alkylsulfamoyl, n is 0 to 2, m is 1 to 2, one X is an H.sub.2 N group and the other X is a radical of the formula ##STR2## in which R.sub.1 and R.sub.2 are independently of each other hydrogen or substituted or unsubstituted C.sub.1-4 -alkyl, A is C.sub.2-4 -alkylene which can be substituted by halogen, hydroxyl, carboxyl, sulfo, phenyl, sulfophenyl or C.sub.1-4 -alkoxycarbonyl, or is cyclohexylene which can be substituted by C.sub.1-4 -alkyl, or in which the group --N(R.sub.1)--A--N(R.sub.
Abstract: A process for the simultaneous caustic treatment and dyeing of cotton goods with vat dyes by the pad steam process, wherein the goods, after being padded with a dye liquor and dried, are subjected to a caustic treatment step and subsequently further treated in conventional manner.
Abstract: Reactive dyes of the formula ##STR1## in which D is the radical of a diazo component of the benzene, naphthalene, azobenzene, naphthylazobenzene, azonaphthalene or phenylazonaphthalene series, K is the radical of a coupling component of the benzene or naphthalene series or of the heterocyclic series, except a pyrazolone radical, R.sub.1 and R.sub.2, independently of each other, are each hydrogen or an unsubstituted or substituted C.sub.1-4 -alkyl radical, and X.sub.1 and X.sub.2, independently of each other, are each unsubstituted or substituted aminofluoro-s-triazinyl, are particularly suitable for dyeing and printing cellulose-containing fibre materials and produce, in high dyeing yield, dyeings and prints having good fastness properties.
Abstract: A mixture comprising a yellow dye and a red dye each of formula I and a grey dye of formula II is employed in accordance with claim 1 for the trichromatic dyeing of leather.
Abstract: The invention relates to milbemycin derivatives of formula I ##STR1## wherein R.sub.1 is an aliphatic or aromatic radical or is a pyridyl ring or a heterocyclic oxygen-containing 5- or 6-membered ring, all of which may also be bound through oxygen, and R.sub.2 is methyl, ethyl or isopropyl. These compounds are suitable for controlling arthropode species such as injurious insects or endo- or ectoparasites of animals and are employed in the form of compositions. The compounds can also be used as intermediates for obtaining further milbemycin derivatives.
Abstract: The invention relates to novel useful reactive dyes of the formula I ##STR1## in which: F is a radical selected from the group consisting of metal-free or metal-containing monoazo or disazo dyes containing at least one --SO.sub.3 H group, anthraquinone dyes, sulfophthalocyanine dyes, formazan dyes, phenazine dyes, oxanine dyes and nitroaryl dyes,R is hydrogen, C.sub.1 -C.sub.4 alkyl which is unsubstituted or substituted with --COOH or --SO.sub.3 H, cyanoethyl, or hydroxyethyl, X is fluorine, chlorine, bromine, --SO.sub.3 H, phenylsulfonyl or C.sub.1 -C.sub.4 -alkylsulfonyl,P is 1 or 2 andA is a radical of the formula ##STR2## in which: the groups designated "alk" are independently of each other straight or branched polymethylene radicals having 2 to 6 carbon atoms, andZ is .beta.-halogenoethyl, vinyl, .beta.-sulfatoethyl, .beta.-thiosulfatoethyl or .beta.acetoxyethyl.
Abstract: The invention relates to novel monoclonal antibodies having a high affinity for human renin, derivatives thereof, processes for the preparation of these antibodies and their derivatives, hybridoma cell lines that produce these antibodies, and to processes for the preparation of said hybridoma cells lines. The monoclonal antibodies according to the invention and their derivatives can be used for the qualitative and quantitative determination of human renin and structurally similar renin, for the purification of human renin and structurally similar renin and for the treatment of high blood pressure and cardiac insufficiency.
Type:
Grant
Filed:
March 28, 1985
Date of Patent:
October 25, 1988
Assignee:
Ciba-Geigy Corporation
Inventors:
Christoph Heusser, Rudolf H. Andreatta, Sefik Alkan, Jeanette Wood
Abstract: The invention relates to novel 3-phenyl-4-cyanopyrrole derivatives of the general formula ##STR1## wherein X has the following meanings: A: hydrogen or CO--R.sub.1, wherein R.sub.1 is C.sub.1 -C.sub.6 alkyl which is unsubstituted or substituted by halogen or C.sub.1 -C.sub.3 alkoxy; or is C.sub.3 -C.sub.6 -alkenyl, C.sub.3 -C.sub.6 alkynyl, or C.sub.1 -C.sub.6 alkoxy which is unsubstituted or substituted by halogen or C.sub.1 -C.sub.3 alkoxy; or is C.sub.3 -C.sub.6 alkenyloxy, C.sub.3 -C.sub.6 cycloalkyl or tetrahydrofur-2-yl;B: S--R.sub.2, wherein R.sub.2 is C.sub.1 -C.sub.3 haloalkyl;C: CH(Y)R.sub.3, wherein R.sub.3 is hydrogen or C.sub.1 -C.sub.8 haloalkyl and Y is hydroxy, halogen or OC(O)R.sub.4, wherein R.sub.4 is C.sub.1 -C.sub.8 alkyl, C.sub.1 -C.sub.8 -haloalkyl, C.sub.2 -C.sub.6 alkenyl, tetrahydrofur-2-yl, tetrahydropyran-2-yl or C.sub.1 -C.sub.6 alkoxycarbonyl;D: CH.sub.2 --Z, wherein Z is one of the groups ##STR2## in which formula each of R.sub.5 and R.sub.
Abstract: Intermediates for the production of microbicidal pyrrolines of the formula ##STR1## in which R is halogen, C.sub.1 -C.sub.6 -alkyl or C.sub.1 14 C.sub.6 -haloalkyl, and n is 0, 1 or 2, and a method of converting the pyrrolines to phytofungicidal pyrroles by oxidation with bromine or oxygen. Catalysts are provided for the oxidation with oxygen.
Abstract: Acid half esters of the formula ##STR1## wherein R is an aliphatic radical of 16 to 24 carbon atoms, one of Y.sub.1 and Y.sub.2 is hydrogen and the other is phenyl, one of X.sub.1 and X.sub.2 is hydrogen and the other is methyl, one of Z.sub.1 and Z.sub.2 is hydrogen and the other is the maleic acid radical or the phthalic acid radical, m.sub.1 and m.sub.2 are each 0 or 1, s.sub.1, s.sub.2, p.sub.1 and p.sub.2 are integers, with the sum of s.sub.1 +s.sub.2 being 5 to 12 and the sum of p.sub.1 +p.sub.2 is 5 to 30.These compounds are suitable for a wide range of utilities in textile application. In particular, they are used as assistants for dyeing wool-containing fibre materials with anionic dyes or mixtures of dyes.
Abstract: The invention relates to ecto- and endoparasitic milbemycins of formula I ##STR1## wherein R is methyl, ethyl, isopropyl or sec-butyl;R.sub.1 is hydrogen, fluorine or C.sub.1 -C.sub.4 alkyl;R.sub.2 is one of the groups ##STR2## in which formulaeis a value from 2 to 6;X is oxygen or sulfur;R.sub.3 is halogen; andR.sub.4 is hydrogen, C.sub.1 -C.sub.12 alkoxy, C.sub.3 -C.sub.7 cycloalkoxy or C.sub.2 -C.sub.6 alkenyloxy; or C.sub.1 -C.sub.18 alkyl which is unsubstituted or substituted by halogen, C.sub.1 -C.sub.4 alkoxy, hydroxy and/or COOG, G being hydrogen, an alkali metal cation or an alkaline earth metal cation; or R.sub.4 is C.sub.3 -C.sub.7 cycloalkyl which is unsubstituted or substituted by halogen and/or C.sub.1 -C.sub.4 alkyl;C.sub.2 -C.sub.18 alkenyl which is unsubstituted or substituted by halogen;C.sub.2 -C.sub.18 alkynyl which is unsubstituted or substituted by halogen;phenyl which is unsubstituted or substituted by halogen, C.sub.1 -C.sub.4 alkyl C.sub.1 -C.sub.4 alkoxy, nitro, cyano and/or C.sub.
Abstract: Mixtures of fluorescent whitening agents consisting of 51 to 99% by weight of a symmetrically or unsymmetrically substituted first 1,4-bis(cyanostyryl)benzene and 49 to 1% by weight of an unsymmetrically substituted second 1,4-bis(cyanostyryl)benzene that differs from the first, a process for the preparation of said mixtures by condensing terephthalaldehyde with a di(C.sub.1 -C.sub.4) alkylphosphonomethylbenzonitrile to cyano-4-formylstilbene, which is further condensed, either direct or after isolation, with at least one other di(C.sub.1 -C.sub.4)alkylphosphonomethylbenzonitrile, the use of these mixtures for whitening polyester fibres, and compositions containing said mixtures for whitening polyester fibres.
Type:
Grant
Filed:
March 12, 1987
Date of Patent:
October 18, 1988
Assignee:
Ciba-Geigy Corporation
Inventors:
Leonardo Guglielmetti, Hans R. Meyer, Dieter Reinehr, Kurt Weber
Abstract: A process for the preparation of dyes of formula (1) as indicated in claim 1 or of mixtures of such dyes is described.The dyes of formula (1) are obtained by reacting 1,4-diaminoanthraquinone-2,3-dicarboximide, or the corresponding monoimino compound, with an amine and in the absence of a solvent. Dye mixtures are prepared by subsequently partially transamidating the resultant product.
Abstract: A process for the photochemical stabilization of undyed and dyed polyamide fibre material or blends thereof with other fibre materials, which comprises treating the fibre material with a mixture of (A) an organic copper complex, (B) a light stabilizer and, if desired, (C) an antioxidant, an agent for carrying out the process and the fibre material treated with the agent are described.