Patents Represented by Attorney Michael B. Martin

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  • Indole piperazine platelet activating factor antagonists
    Patent number: 5654305
    Abstract: The present invention provides compounds of formula ##STR1## wherein Y is >C.dbd.O or >S(O).sub.t wherein t is 1 or 2 and the pharmaceutically acceptable salts thereof which are potent antagonists of PAF and are useful in the treatment of PAF-related disorders including asthma, rhinitis, shock, respiratory distress syndrome, acute inflammation, transplanted organ rejection, gastrointestinal ulceration, allergic skin diseases, delayed cellular immunity, parturition, fetal lung maturation, and cellular differentiation.
    Type: Grant
    Filed: July 2, 1996
    Date of Patent: August 5, 1997
    Assignee: Abbott Laboratories
    Inventors: George S. Sheppard, Steven K. Davidsen, James B. Summers, George M. Carrera, Jr.