Patents Represented by Attorney, Agent or Law Firm Michael J. Ram
  • Patent number: 6335443
    Abstract: A process for the synthetic generation of high affinity, iron binding compounds known as Exochelins, and more particularly, to a synthetic process for making Exochelins and to modifications to these newly synthesized compounds to vary their physiological properties, including applications of these newly synthesized and utile compounds for diagnosing and treating disease in mammals.
    Type: Grant
    Filed: March 5, 1999
    Date of Patent: January 1, 2002
    Assignee: Keystone Biomedical, Inc.
    Inventors: Leo S. Geraci, Stuart G. Levy, James P. Hudspeth, Richard L. Buswell, Jay F. Stearns
  • Patent number: 6323372
    Abstract: New icosahedral borohydrates Cs2[closo-B12(OH)12]; Cs[closo-1-H-1-CB11(OH)11]; and closo-1,12-H2-1,12-C2B10(OH)10 are disclosed. Also set forth are their preparation by refluxing the icosahedral boranes [closo-B12H12]2−, [closo-1-CB11H12]− and closo-1,12-(CH2OH)2-1,12-C2B10H10 with a hydroxylating agent, preferably 30%w hydrogen peroxide.
    Type: Grant
    Filed: April 10, 2000
    Date of Patent: November 27, 2001
    Assignee: The Regents of the University of California
    Inventors: M. Frederick Hawthorne, Toralf Peymann, Axel Hans-Joachim Herzog
  • Patent number: 6323625
    Abstract: An electrical system for a turbine/alternator comprising a gas driven turbine and permanent magnet alternator rotor rotating on a common shaft and comprising an inverter circuit connected either to an AC output circuit or the stator windings of the alternator. A control circuit during start-up mode connects the inverter circuit to the stator windings of the alternator and during the power generation mode it switches and connects the inverter circuit to the AC output circuit. Thus, during the start-up mode, the alternator functions as a motor to raise the speed of the turbine to a safe ignition speed and in the power generation mode the system provides power through the AC output circuit, electrical power having a frequency and voltage unrelated to the rotational speed of the turbine/alternator.
    Type: Grant
    Filed: July 14, 1998
    Date of Patent: November 27, 2001
    Inventor: Brij B. Bhargava
  • Patent number: 6291528
    Abstract: A method of treating and a composition for treating female sexual arousal dysfunction, comprising administering to the patient a unit dose of a formulation comprising an effective amount of a prostaglandin, selected from prostaglandin E1, prostaglandin E2, pharmaceutically acceptable salts thereof and physiologically acceptable esters thereof, wherein the prostaglandin is formulated with prostaglandin F2&agr;, together with a pharmaceutically acceptable delivery medium and/or a lubricant.
    Type: Grant
    Filed: October 20, 1999
    Date of Patent: September 18, 2001
    Inventor: Nathan Earl Scott
  • Patent number: 6279878
    Abstract: PLZT piezoelectric ceramics having the general formula (Pb1−xLax)(ZryTi1−y)1−(x/4)−zMa+4z/a O3 are fabricated in a hot forging process using PbO, TiO2, ZrO2, and La2O3 powders with Nb2O5 and Ta2O5 added to provide 2.0-3.0% Nb5+ (mole %) and 2.0-3.0% Ta+5 (mole %) as a dopant. ZrO2 and TiO2 powders are mixed at a molar ratio of y/(1−y), the preferred molar ratio being 55/45, calcined at approximately 1300° C.-1500° C., ball milled in acetone, and evaporated to a dry powder. The mixture of ZrO2 and TiO2 is then combined with PbO2, La2O3, Nb2O5 and Ta2O5 powders, and the new mixture is ball milled in acetone, evaporated to a dry powder, calcined at approximately 700°-850° C., and sifted to obtain a particle size of approximately 0.5-1.5 &mgr;m. The final Nb/Ta-doped PLZT powder is formed into the desired shape by cold pressing followed by sintering at approximately 1000° C.-1150° C. in oxygen.
    Type: Grant
    Filed: April 28, 2000
    Date of Patent: August 28, 2001
    Assignee: Rockwell Technologies, LLC
    Inventors: Jeffrey G. Nelson, Ratnakar R. Neurgaonkar
  • Patent number: 6279589
    Abstract: An apparatus for cleaning and disinfecting containers, such as elongated, walled containers, such as truck trailers, rail cars, airplane holds, or ship containers, generally comprises a rolling trolley which produces a disinfecting mixture of ozone and water at high pressure and delivers the disinfectant by a hose to a rolling dolly which enters into the container. The trolley supports the dolly at a height conductive for entry into the container. The dolly is manually pushed into the container. Rotating spray nozzles on the dolly deliver the disinfectant at high pressure to the inside walls of the container. The nozzles are directed at an angle fore or aft of their radius of rotation such that the spray strikes the wall of the container at a sheer angle. Hose retrieval apparatus on the trolley retrieves the hose so as to pull the dolly from the container at a desired speed, thereby controlling the cleaning/disinfecting rate.
    Type: Grant
    Filed: September 20, 1999
    Date of Patent: August 28, 2001
    Assignee: AG Tech International, Inc.
    Inventor: Mark D. Goodley
  • Patent number: 6274116
    Abstract: Boron neutron capture therapy can utilize XyB20H17L where X is an alkali metal, y is 1 to 4, and L is a two electron donor such as NH3, and Na2B10H9NCO, among others. These borane salts may be used free or encapsulated in liposomes. Liposomes may also have embedded within their bilayers carboranes to increase the amount of delivered 10B and/or to increase the tumor specificity of the liposome.
    Type: Grant
    Filed: March 29, 1999
    Date of Patent: August 14, 2001
    Assignee: Reagents of the University of California
    Inventors: M. Frederick Hawthorne, Debra Arlene Feaks, Kenneth John Shelly
  • Patent number: 6265615
    Abstract: A new polymeric material, a process for forming the material and method of using the material to separate enantiomers of chiral compounds, particularly amino acids and pharmaceuticals are disclosed. A polymeric material can be formed from polyaniline doped with a chiral acid and then extracted with a suitable base. This leaves behind a polymeric material which preferentially traps, and then selectively releases, one enantiomer of a chiral mixture brought in contact with the surface of the polymeric material. In particular, when polyaniline is doped with either R- or S-camphorsulfonic acid (CSA) it takes on a chiral structure. Removing the chiral acid dopant leads to a new chiral polyaniline. The dedoped chiral polyanilines have the ability to discriminate among enantiomers of many compounds which exist in chiral mixtures.
    Type: Grant
    Filed: May 28, 1999
    Date of Patent: July 24, 2001
    Assignee: The Regents of the University of California
    Inventors: Richard B. Kaner, Charles M. Knobler, Hailan Guo
  • Patent number: 6248916
    Abstract: A general synthetic method has been developed for the rapid and efficient production of a variety of boron-rich macromolecules suitable for conjugation with inclusion in receptor-mediated delivery systems as well as other delivery systems. Preparation techniques have been developed to yield precisely ordered oligophosphates which are soluble, hydrophilic, may be homogeneous, and may be prepared with a variety of functional groups.
    Type: Grant
    Filed: January 5, 1999
    Date of Patent: June 19, 2001
    Assignee: Regents of the University of California
    Inventors: Robert R. Kane, M. Frederick Hawthorne
  • Patent number: 6244438
    Abstract: A universal golf club securer and organizer for securing golf clubs in a fixed position in a golf bag which consists of a series of individual resilient clips having adjustable positions on a support bar thereby compensating for the width of any club in a set of golf clubs. The support bar is attached to a golf bag by means of a rod and clamp system which is adjustable to the height of any set of golf clubs.
    Type: Grant
    Filed: September 4, 1998
    Date of Patent: June 12, 2001
    Inventor: Robert J. Weinmeier
  • Patent number: 6241739
    Abstract: This invention provides a treatment tool and tissue collection system, for remove of outer layers of skin to provide a revitalized, fresh skin surface, and a method of using same, comprising an abrasive tipped tool mounted on the end of a tube, said tube being connected to a source of vacuum. The vacuum aids in maintaining intimate contact between the abrasive tip and the skin during the treatment process and transports the removed tissue to a collection container.
    Type: Grant
    Filed: November 12, 1999
    Date of Patent: June 5, 2001
    Assignee: Altair Instruments, Inc.
    Inventor: Stephen H. Waldron
  • Patent number: 6239853
    Abstract: An assembly for restricting the angle of vision of an image emitted from an LCD screen comprising a linearly parallel arrangement of two polarizing films with at least two waveplates there between. The transmission planes of the polarizing films are at an angle, preferrably 90° to each other. At least two parallel waveplates are positioned between, the polarizing films. Each waveplate has parallel transmitting regions alternating between birefringent and isotropic regions. The waveplates are positioned in a spaced apart relationship to each other such that substantially orthogonal light passing through the first polarizing screen and one of the birefringent or isotropic alternating transmitting regions of the first waveplate will pass through the other of the alternating striped transmitting regions of the second waveplate. Light so transmitted will then pass through the second polarizing film and be viewable.
    Type: Grant
    Filed: October 1, 1999
    Date of Patent: May 29, 2001
    Assignee: Rockwell Science Center, LLC
    Inventors: Bruce K. Winker, Donald B. Taber
  • Patent number: 6202476
    Abstract: A method of and apparatus for testing for leaks in a package is provided. The package is compressed under the weight of a test element (16). The position of the test element is measured at least twice and the positions are compared to check movement of the test head due to gas or liquid escape from the package.
    Type: Grant
    Filed: February 24, 1998
    Date of Patent: March 20, 2001
    Assignee: Testamatic Limited
    Inventor: Christopher Fenlon
  • Patent number: 6197815
    Abstract: Metal amino acid chelates for animals are beneficial for facilitating and promoting growth by increasing desired metallic ion uptake. The present invention is directed to a process for providing an animal fed additive by preparing metal amino acid chelates, and the metal amino acid chelate growth facilitator, promoter and enhancer prepared by the process.
    Type: Grant
    Filed: March 18, 1998
    Date of Patent: March 6, 2001
    Assignee: J.H. Biotech, Inc.
    Inventor: Hsinhung John Hsu
  • Patent number: 6168436
    Abstract: A universal dental implant abutment system is provided which includes an abutment collar and a fixation screw. The abutment collar has a proximal end portion adapted for fixation to a dental prosthesis and a distal end portion adapted for coupling with an implant body. The fixation screw is disposed within a longitudinal bore of the abutment collar and has a threaded distal end for securement to the implant body. The fixation screw has a head portion formed on a proximal end thereof, the head portion having a longitudinally directed bore formed therein. The longitudinal bore of the head of the fixation screw is formed with two longitudinally spaced sections. One section has a non-circular cross-sectional contour adapted for receiving a driving tool therein. The other section has internal threads formed therein adapted for threaded engagement with a retention fastener of a prosthesis.
    Type: Grant
    Filed: June 18, 1997
    Date of Patent: January 2, 2001
    Inventor: Gary O'Brien
  • Patent number: 5786326
    Abstract: A method for the treatment of atherosclerosis and vascular injury using exochelins, and more particularly exochelins of Mycobacterium tuberculosis, to prevent vascular smooth muscle cell proliferation. Delivery of an effective amount of a desferri-Exochelins to a living organism such as an animal or a human by oral, intravenous or direct delivery to the site at which the effect is desired will protect blood vessels in a living organism from restenosis following angioplasty or vascular surgery and will prevent or slow the progression of atherosclerosis, systemic hypertension, radiation damage to the vasculature, stenosis or closure of bypass grafts to the coronary arteries or other blood vessels following a surgical procedure and various forms of pulmonary hypertension.
    Type: Grant
    Filed: February 6, 1997
    Date of Patent: July 28, 1998
    Inventor: Lawrence D. Horwitz
  • Patent number: 5747118
    Abstract: A chemical transport process which is enhanced by a plasma formed in a substantially oxygen free hydrogen environment for formation of microcrystalline diamond films at a relatively low deposition temperature and a rate of about 1 .mu.m/hr. The process, performed at 80 to 180 Torr and a current density of about 1 amp/cm.sup.2 of substrate, can be scaled to deposit films on large areas. The invention further comprises doped diamond films produced by the process, said product having a well-faceted microcrystalline structure with x-ray diffraction pattern and Raman spectra indicative of a predominately diamond structure. The doped diamond films can function as n-type and p-type semiconductors.
    Type: Grant
    Filed: August 2, 1995
    Date of Patent: May 5, 1998
    Assignee: The Regents of the University of California
    Inventors: Rointan F. Bunshah, Hans J. Doerr, Shyankay Jou
  • Patent number: 5743080
    Abstract: A vapor-air steam engine is described which operates at high pressure and utilizes a working fluid consisting of a mixture of compressed uncombusted air components, fuel combustion products and steam.In the new cycle described, working fluid is provided at constant pressure and temperatures. Combustion air is supplied adiabatically by one or more stages of compression. Fuel is injected at pressure as needed. At least about 40% to all of compressed air is burned. Inert liquid is injected at high pressure to produce steam and thus provide an inert high specific heat diluent vapor required for internal cooling of an internal combustion turbine or other type system.The use of extensive liquid injection inhibits the formation of pollutants, increases the efficiency and horsepower of an engine, and reduces specific fuel consumption. The new cycle may also be operated open or closed; in the latter case, the liquid may be recouped via condensation for regenerative reuse.
    Type: Grant
    Filed: April 26, 1994
    Date of Patent: April 28, 1998
    Assignee: Ginter Vast Corporation
    Inventor: J. Lyell Ginter
  • Patent number: 5724824
    Abstract: A novel delivery system for delivering a fine fog of water through a plurality of nozzles to absorb heat through evaporation. The delivery system comprises the combination of a water supply tank, an air compressor, solenoid valve and an electronic control module for controlling the operation of valve and compressor to allow an operator to adjust the displacement rate of fog as well as providing the operator a choice between continuous, intermittent and pulsing operation.
    Type: Grant
    Filed: December 12, 1996
    Date of Patent: March 10, 1998
    Inventor: David A. Parsons
  • Patent number: D442593
    Type: Grant
    Filed: August 12, 1999
    Date of Patent: May 22, 2001
    Inventors: Kimberly Vaghefi, Farid Vaghefi