Patents Represented by Attorney, Agent or Law Firm Millen White Zelano & Branigan
  • Process for production of a modified acetalated polyvinyl alcohol
    Patent number: 8178618
    Abstract: The invention relates to a method for modifying acetalated polyvinyl alcohols comprising reacting a melt acetalated polyvinyl alcohols with epoxides. The invention also relates to uses of the resultant modifying acetalated polyvinyl alcohols, including uses in ceramic applications.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: May 15, 2012
    Assignees: Kuraray Europe GmbH, Kuraray Co. Ltd.
    Inventors: Michael Frank, Sven Köhnen, Matthias Gutweiler, Kaoru Ikeda
  • Process for the preparation of multimetallic catalysts that can be used in reactions for transformation of hydrocarbons
    Patent number: 8178735
    Abstract: A process for the treatment of an olefinic fraction, using a catalyst prepared by a process comprising: a) The preparation of a colloidal oxide suspension of a first metal M1 by the neutralization of a basic solution by an acidic mineral solution that contains the precursor of the metal M1, b) Bringing into contact the precursor of the promoter M2, either directly in its crystallized form or after dissolution in aqueous phase, with the colloidal suspension that is obtained in stage a), c) Bringing into contact the colloidal suspension that is obtained in stage b) with the substrate, d) Drying at a temperature of between 30° C. and 200° C., under a flow of air.
    Type: Grant
    Filed: April 25, 2011
    Date of Patent: May 15, 2012
    Assignee: IFP Energies nouvelles
    Inventors: Vincent Coupard, Denis Uzio, Carine Petit-Clair, Lars Fischer, Frederic Portejole
  • Inositol-phosphate derivatives and method of detecting inositol-1-phosphate
    Patent number: 8178704
    Abstract: The present invention relates to inositol phosphate derivatives, in which the inositol phosphate is substituted with one or two reactive groups G or one or two conjugated substances or molecules M, said reactive group(s) G or said substance(s) or molecule(s) M being linked to IP1 via a linkage group L, M being chosen from the following group: a tracer, an immunogen, a member of a binding partner pair, a solid support. Application: tools allowing the study of the inositol phosphate cycle and therefore, indirectly, the study of seven transmembrane domain receptors coupled to phospholipase C, receptors having a tyrosine kinase activity, and in general enzymes involved in the variations of the intracellular concentration of IP1.
    Type: Grant
    Filed: December 2, 2005
    Date of Patent: May 15, 2012
    Assignee: CIS Bio International
    Inventors: Hervé Bazin, Hervé Ansanay, Eric Trinquet, Gérard Mathis
  • Pyridopyrazinones derivatives insulin secretion stimulators, methods for obtaining them and use thereof for the treatment of diabetes
    Patent number: 8178556
    Abstract: Described are pyridopyrazinone derivatives of formula (I), wherein X, Y, Z, W, A and R1 are as defined in claim 1, as insulin secretion stimulators. Also described is the preparation and use of these pyridopyrazinone derivatives for the prophylaxis and/or treatment of diabetes and pathologies associated.
    Type: Grant
    Filed: February 27, 2009
    Date of Patent: May 15, 2012
    Assignee: Merck Patent Gesellschaft MIT Beschraenkter Haftung
    Inventors: Gerard Botton, Eric Valeur, Micheline Kergoat, Christine Charon, Samer Elbawab
  • Vehicle door frame and method of producing the same
    Patent number: 8172125
    Abstract: A vehicle door frame includes first and second door frame members which are positioned end-to-end to be butt-welded to each other, wherein each of the first and second door frame members includes a design part, an enclosed section provided on a vehicle interior side, a connecting part which connects an inner surface of the design part with the enclosed section; and first and second dam protrusions which project from the inner surface of the design part and are positioned on opposite sides of the connecting part, respectively. Molten metal is present in the first and second spaces after the molten metal has melted and passed through the inner surface of the design part from the outer surface thereof upon butted ends of the first and second door frame members being butt-welded to each other from the outer surface of the design part.
    Type: Grant
    Filed: August 30, 2010
    Date of Patent: May 8, 2012
    Assignee: Shiroki Corporation
    Inventors: Takayuki Okada, Kenji Shimizu, Go Yamane, Masaki Koyama
  • Benzyl, amines, a process for their production and their use as anti-inflammatory agents
    Patent number: 8173676
    Abstract: The present invention relates to the compounds of formula I, processes for their production and their use as anti-inflammatory agents.
    Type: Grant
    Filed: August 15, 2011
    Date of Patent: May 8, 2012
    Assignees: Bayer Pharma AG, AstraZeneca AB
    Inventors: Markus Berger, Jan Dahmen, Hartmut Rehwinkel, Stefan Jaroch, Heike Schäcke
  • Pyridiazinone derivatives for the treatment of tumours
    Patent number: 8173653
    Abstract: Compounds of the formula (I), in which R1, R2 and R3 have the meanings indicated in claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumors.
    Type: Grant
    Filed: November 7, 2006
    Date of Patent: May 8, 2012
    Assignee: Merck Patent Gesellschaft MIT Beschraenkter Haftung
    Inventors: Dieter Dorsch, Oliver Schadt, Andree Blaukat
  • Polymers derived from bis(thienocyclopenta) benzothiadiazole and their use as organic semiconductors
    Patent number: 8173766
    Abstract: The invention relates to conjugated polymers comprising bis(thienocyclopenta)benzothiadiazole units or derivatives thereof, to methods of their preparation, to novel monomer units used therein, to the use of the polymers in organic electronic (OE) devices, and to OE devices comprising the polymers.
    Type: Grant
    Filed: August 20, 2009
    Date of Patent: May 8, 2012
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Steven Tierney, Clare Bailey, William Mitchell
  • Fiber reinforced plastic drilling anchor
    Patent number: 8172484
    Abstract: The invention relates to a fiber-reinforced plastic drilling anchor comprising an axial bore that runs along the entire length thereof, fibers which extend in the longitudinal direction thereof, and fibers that extend at an angle to the longitudinal direction thereof. A first layer of fibers that extend at an angle to the longitudinal direction of the drilling anchor is surrounded by a second layer of fibers extending in the longitudinal direction of the drilling anchor, and the second layer of fibers is surrounded by a third layer of fibers extending at an angle to the longitudinal direction of the drilling anchor. The inventive drilling anchor further comprises a thread which extends along the entire length thereof and is molded into at least one outer fiber layer of the drilling anchor. The invention also relates to a method for producing such a drilling anchor.
    Type: Grant
    Filed: May 29, 2007
    Date of Patent: May 8, 2012
    Assignee: FiRep Rebar Technology GmbH
    Inventor: Kenichi Tsukamoto
  • Liquid-crystalline medium
    Patent number: 8168081
    Abstract: The invention relates to a liquid-crystalline medium based on a mixture of dielectrically negative, polar compounds which comprises at least one compound of the formula I in which the parameters have the meanings indicated in claim 1, to the use thereof in an electro-optical display, particularly in an active-matrix display based on the VA, ECB, PALC, FFS or IPS effect, and to displays of this type.
    Type: Grant
    Filed: July 17, 2007
    Date of Patent: May 1, 2012
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Melanie Klasen-Memmer, Georg Bernatz, Izumi Saito, Matthias Bremer, Lars Lietzau, Volker Reiffenrath
  • Mediators of hedgehog signaling pathways, compositions and uses related thereto
    Patent number: 8168653
    Abstract: The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function comprising contacting the cell with a hedgehog antagonist of formula (I) in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonize smoothened or hedgehog activity.
    Type: Grant
    Filed: August 2, 2010
    Date of Patent: May 1, 2012
    Assignees: Curis, Inc., Genentech, Inc.
    Inventors: Oivin M. Guicherit, Edward Andrew Boyd, Shirley Ann Brunton, Stephen Price, John Harry Alexander Stibbard, Colin H. Mackinnon
  • Electro-optical light control element, electro-optical display and control medium
    Patent number: 8168083
    Abstract: The present invention relates to an electro-optical light-modulation element of the FFS type, and to electro-optical displays and display systems, such as, for example, television screens and computer monitors, which contain elements of this type. The light-modulation elements according to the invention contain a liquid-crystalline modulation medium which has optimised elastic constants and are distinguished, in particular, by high contrast and/or optimised transmission in addition to good contrast, a low viewing-angle dependence, short response times and low addressing voltages. The present invention likewise relates to the liquid-crystalline modulation media used in the electro-optical light-modulation elements.
    Type: Grant
    Filed: August 26, 2008
    Date of Patent: May 1, 2012
    Assignee: Merck Patent Gesellschaft MIT Beschraenkter Haftung
    Inventors: Mark Goebel, Markus Czanta
  • Management of breakthrough bleeding in extended hormonal contraceptive regimens
    Patent number: 8163721
    Abstract: The present invention relates to a flexible extended use regimen for a hormonal contraceptive useful to manage bleeding problems associated with fixed extended use of hormonal contraceptives and to a pharmaceutical package containing the respective hormonal contraceptive.
    Type: Grant
    Filed: May 2, 2005
    Date of Patent: April 24, 2012
    Assignee: Bayer Pharma AG
    Inventor: Andreas Sachse
  • Cyclohexene compounds for liquid-crystalline mixtures
    Patent number: 8163200
    Abstract: The invention relates to liquid-crystalline compounds of the formula I in which R1, R2, A1, A2, A3, A4, Z1, Z2, Z3, V, a, b and c have the meanings indicated in Claim 1, and to liquid-crystalline media comprising at least one compound of the formula I, and to electro-optical displays containing a liquid-crystalline medium of this type.
    Type: Grant
    Filed: July 18, 2007
    Date of Patent: April 24, 2012
    Assignee: Merck Patent Gesellschaft MIT Beschraenkter Haftung
    Inventors: Lars Lietzau, Markus Czanta, Atsutaka Manabe, Kai Jaehrling
  • Process for the production of monodisperse SiOparticles
    Patent number: 8163260
    Abstract: The present invention relates to processes for the production of monodisperse SiO2 particles by hydrolytic polycondensation of tetraalkoxysilanes and/or organotrialkoxysilanes, in which the hydrolytic polycondensation is carried out in a medium comprising water, one or more solubilizers and one or more amines, and in which highly monodisperse, non-porous particles are obtained. The present invention likewise relates to powders obtainable by the processes, and to the use thereof.
    Type: Grant
    Filed: February 10, 2005
    Date of Patent: April 24, 2012
    Assignee: Merck Patent GmbH
    Inventor: Armin Kuebelbeck
  • 2-arylthiazole-4-carboxamide derivatives, their preparation and use as pharmaceuticals
    Patent number: 8163739
    Abstract: The present invention relates to 2-arylthiazole-4-carboxamide derivatives of the formula (I), the use thereof as medicament for the treatment of various disorders, and processes for the preparation thereof
    Type: Grant
    Filed: December 10, 2008
    Date of Patent: April 24, 2012
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Ulrich Bothe, Arne Von Bonin, Duy Nguyen, Ulf Bomer, Judith Guenther
  • Gas-lift valve and method of use
    Patent number: 8162060
    Abstract: A gas-lift valve comprising an elongated vertically orientated tubular body with inlet ports positioned for communication with the inlet ports of a gas-lift valve mandrel, a valve seat and valve port at the upper end of the valve body, a movable gas charged dome positioned within the body below the valve seat, a valve ball assembly attached to the dome, and a collapsible bellows positioned to move the dome and manipulate the valve ball assembly downward onto and off of the valve seat in response to pressure from said inlet ports of the valve body and pressure on the seat and thereby allow injection gas to flow upward through the valve port to exit at the upper end of the valve body. A tubular latch is provided with a removable plug to provide for pressure testing and completion of the well with only one wireline trip.
    Type: Grant
    Filed: October 21, 2009
    Date of Patent: April 24, 2012
    Assignee: Eagle Gas Lift, LLC.
    Inventor: Vic Arthur Randazzo
  • Start-up process for a unit for producing highly thermally-integrated hydrogen by reforming a hydrocarbon feedstock
    Patent number: 8163046
    Abstract: The invention relates to a start-up process for a unit for producing highly thermally-integrated hydrogen by reforming a hydrocarbon feedstock that comprises a stage a wherein a burner whose purpose is to ensure start-up is supplied with a mixture of hydrocarbon feedstock and air, a stage b wherein a water stream is evaporated by indirect heat exchange with at least one of the hot streams of the process, a stage c wherein the hydrocarbon feedstock to be reformed is evaporated and heated and then introduced in gaseous form in a reforming reactor, and a stage d wherein the start-up burner is shut down, and a burner that is in permanent operation is lit.
    Type: Grant
    Filed: March 28, 2008
    Date of Patent: April 24, 2012
    Assignee: IFP Energies Nouvelles
    Inventors: Christophe Boyer, Fabrice Giroudiere, Stéphane Bertholin, Aziz Sattar
  • Pouch
    Patent number: D658075
    Type: Grant
    Filed: August 23, 2011
    Date of Patent: April 24, 2012
    Assignee: Hosokawa Yoko Co., Ltd.
    Inventor: Kazuhiro Umenaka
  • Ribbon flag
    Patent number: D659050
    Type: Grant
    Filed: August 9, 2011
    Date of Patent: May 8, 2012
    Inventors: Madelyn Sussman, Barbara Sussman