Abstract: The present invention relates to a compound which is a polysaccharide derivative of EPO, or of an EPO like protein, wherein the polysaccharide is anionic and comprises between 2 and 200 saccharide units. The present invention also relates to pharmaceutical compositions comprising the novel compounds, and methods for making the novel compounds.
Type:
Grant
Filed:
July 25, 2007
Date of Patent:
October 30, 2012
Assignee:
Lipoxen Technologies Limited
Inventors:
Sanjay Jain, Peter Laing, Gregory Gregoriadis, Norbert Oskar Rumpf
Abstract: A method, system and graphical user interface for a chat system is disclosed. One aspect of certain embodiments includes sending target messages to users based on the respective selection and filtering criteria selected by the respective users instead of having users enter topic specific rooms.
Abstract: A method of compensating for differences in characteristics of a plurality of electroluminescent (EL) subpixels having readout transistors, includes providing a first voltage source connected through a first switch to each subpixel's drive transistor and a second voltage source connected through a second switch to each subpixel's EL emitter; providing a current source connected through a third switch, and a current sink connected through a fourth switch, to the readout transistor; providing a test voltage to a subpixel; closing only the first and fourth switches and measuring the readout transistor voltage to provide a first signal representative of characteristics of the drive transistor; closing only the second and third switches and measuring the voltage to provide a second signal representative of characteristics of the EL emitter; repeating for each subpixel; and using the first and second signals for each subpixel to compensate for differences in characteristics of the EL subpixels.
Abstract: Disclosed are processes to increase the relative abundance of a molecule that is present in a test sample at relatively low abundance. The process includes fractionating a sample and immunizing hosts with the fractions. The antibodies produced from the fractionated test sample are directed primarily to molecules that are in relatively high abundance in the test sample fractions. These antibodies are then contacted with the test sample or a test sample to immuno-deplete relatively high abundance molecules from the sample to form a first depleted sample. These steps can be repeated a reiterative process of immuno-subtraction to produce second and third depleted samples where the relative abundance of the “low abundance” molecule is increased.
Abstract: The invention describes a method for diagnosing of septic complications in polytraumatised human or animal patients, said patients being free of traumatic brain injury, by determining the level of the C-type natriuretic peptide (CNP), its precursors or fragments thereof, especially the precursor of the C-type natriuretic peptide (NT-proCNP), in this patient and diagnosing the patient a having septic complications or being at risk of developing septic complications, if the level of CNP, its precursors or fragments thereof, especially NT-proCNP, is increased compared to normal levels.
Type:
Grant
Filed:
March 6, 2008
Date of Patent:
October 30, 2012
Assignee:
Biomedica Medizinprodukte GmbH & Co KG
Inventors:
Soheyl Bahrami, Wolfgang Woloszczuk, Gerhard Hawa
Abstract: A device, method, and graphical user interface for providing maps, directions, and location-based information on a touch screen display are disclosed.
Type:
Grant
Filed:
June 20, 2008
Date of Patent:
October 30, 2012
Assignee:
Apple Inc.
Inventors:
Michael Matas, Chris Blumenberg, Andre M. J. Boule, Stephen O. Lemay, Richard Williamson
Abstract: A method, system and graphical user interface for a chat system is disclosed. One aspect of certain embodiments includes receiving from respective users feedback data regarding the received messages or authors of the received messages and providing the feedback to the respective authors.
Abstract: A pre-crash side airbag device includes a side collision detection sensor, a pre-crash sensor, a main airbag, an auxiliary airbag, and a control unit. The side collision detection sensor detects a collision occurring at the side of a vehicle. The pre-crash sensor detects physical quantities related to the speed of an approaching object. The main airbag is deployed when a control signal is input. The auxiliary airbag is coupled to one side of the main airbag. The control unit controls the deployment of the main airbag and the auxiliary airbag depending on a pre-crash case where a high-speed side collision is expected and a normal case where a low-speed side collision is expected or the measurement value is erroneous.
Type:
Grant
Filed:
November 29, 2010
Date of Patent:
October 30, 2012
Assignee:
Hyundai Motor Company
Inventors:
Hyock In Kwon, Hyeong Ho Choi, Seung Woo Lee, Jae Ho Choi, Jun Yeol Choi
Abstract: The present invention provides materials and methods that can serve as a prosthetic and/or, for tissue engineer applications, as a supporting matrix in the stabilization of the myocardium.
Type:
Grant
Filed:
November 20, 2007
Date of Patent:
October 30, 2012
Assignee:
The Regents of the University of California
Inventors:
Kevin E. Healy, Samuel Thomas Wall, Mark Ratcliffe, Julius Guccione
Abstract: The present invention relates to a compound which is a polysaccharide derivative of GCSF, or of a GCSF like protein, wherein the polysaccharide is anionic and comprises between 2 and 200 saccharide units. The present invention also relates to pharmaceutical compositions comprising the novel compounds, and methods for making the novel compounds.
Type:
Grant
Filed:
July 25, 2007
Date of Patent:
October 30, 2012
Assignee:
Lipoxen Technologies Limited
Inventors:
Sanjay Jain, Peter Laing, Gregory Gregoriadis
Abstract: A mobile device includes a main body having a coupling element mounted thereon, and an expansion module electrically connected to the main body, wherein the expansion module comprises a magnet disposed to apply a magnetic force to the coupling element to couple the expansion module with the main body, and a movement converter configured to move the magnet away from the coupling element so as to decrease the magnetic force between the coupling element and the magnet thereby decoupling the main body from the expansion module.
Abstract: A display panel assembly includes a first substrate having an effective display region for displaying an image and a non-effective display region positioned at a peripheral region outside of the effective display region, a second substrate facing the first substrate, a sealing member disposed along a boundary between the effective display region and the non-effective display region between the first and second substrates, the sealing member including a thermosetting material, and an exothermic member interposed between the sealing member and the first substrate to generate heat for curing the sealing member.
Abstract: A fold-and-dive seat may include a first link bracket, one end of which is pivotally connected to a back frame and the other end of which is pivotally connected to a cushion frame, wherein the one end of the first link bracket is spaced from a folding pivot shaft of the back frame, a second link bracket, one end of which is pivotally connected to a leading end of the cushion frame, and the other end of which is selectively engaged to an upper guide, wherein the upper guide pivotally coupled to the back frame by the folding pivot shaft is slidably coupled to a lower guide fixed to a vehicle body and configured to move along the lower guide, and a locking device selectively holding the second link bracket by engaging the second link bracket to the upper guide so as not to rotate the second link bracket such that the leading end of the cushion frame is not moved downwards.
Type:
Grant
Filed:
November 18, 2009
Date of Patent:
October 23, 2012
Assignees:
Hyundai Motor Company, Kia Motors Corporation
Abstract: Noise on a current to be measured is removed. Horizontal power supply lines (PVDD) are arranged in a horizontal direction and supply a current to pixels in respective corresponding horizontal lines. A switch (8) connects a group of the horizontal power supply lines (PVDD) to a first power supply line (PVDDa) or a second power supply line (PVDDb) disposed outside a pixel region in a switchable manner. Only the horizontal power supply lines (PVDD) in a group to which a pixel to be measured belongs are supplied with power from the second power supply line (PVDDb) so as to measure a current of each pixel in the group, and a current flowing into a power source (PVDDa) connected to a group to which other pixels than the pixel to be measured belong is measured, to thereby calculate a pixel current based on a difference between the two measured currents.
Abstract: A flat display panel cutting apparatus that includes a conveyor for feeding a loaded flat display panel to a cutting area and a spraying area; a cutting tool positioned in the cutting area, for forming primary cracks on the flat display panel, the primary cracks including two or more first cracks spaced apart from each other in the X-axis direction and two or more second cracks spaced apart from each other in the Y-axis direction; and a spraying tool positioned in the spraying area, for growing secondary cracks by spraying high temperature steam onto the first cracks or second cracks of the primary cracks formed on the flat display panel.
Abstract: The present invention relates to metal processing lubricant compositions that are based on polyhydrocarbyl esters of aliphatic polyols, in particular tetrahydrocarbyl esters of pentaerythritol, wherein at least one hydrocarbyl group of the tetrahydrocarbyl ester comprises 6-14 carbon atoms and the other hydrocarbyl groups comprise 6-20 carbon atoms. The compositions are in particular suitable for metal forming operations, e.g. a cold rolling operation, a hot rolling operation or a drawing operation, and metal removing operations, e.g. grinding, milling, cutting, turning and honing.
Type:
Grant
Filed:
November 8, 2007
Date of Patent:
October 23, 2012
Assignee:
Quaker Chemical Corporation
Inventors:
Hendrik L. Mulder, Jan Baptist Andreas Felix Smeulders, Robert A. Herrendorf
Abstract: An apparatus for adjusting deviation of an engine and a continuously variable valve lift device including the same are provided. The apparatus for adjusting deviation of an engine includes an adjustment member connecting a rocker arm to plural output cams, respectively, to adjust lengths between the rocker arm and the output cams, respectively, so that the lengths become equal to or different from each other. The continuously variable valve lift device includes an eccentric cam shaft with eccentric cams installed on its outer periphery, a rocker arm rotatably installed on the eccentric cams to interlock with plural output cams, and apparatus for adjusting deviation provided on the rocker arm to adjust lengths between the rocker arm and the output cams so that the lengths become equal to or different from each other.
Type:
Grant
Filed:
October 5, 2009
Date of Patent:
October 23, 2012
Assignee:
Hyundai Motor Company
Inventors:
Jei Choon Yang, Young Hong Kwak, Ki Uk Shin, Jin Kook Kong, Soo Hyung Woo, Jin Soon Kim, Ki Young Kwon
Abstract: An amine or hydrazide derivative of a sialic acid unit, e.g. in a polysaccharide, is reacted with a bifunctional reagent at least one of the functionalities of which is an ester of N-hydroxy succinimide, to form an amide or hydrazide product. The product has a useful functionality, which allows it to be conjugated, for instance to proteins, drugs, drug delivery systems or the like. The process is of particular utility for derivatising amine groups introduced in sialic acid terminal groups of polysialic acids.
Type:
Grant
Filed:
January 10, 2011
Date of Patent:
October 23, 2012
Assignee:
Lipoxen Technologies Limited
Inventors:
Sanjay Jain, Ioannis Papaioannou, Smita Thobhani
Abstract: The invention relates to compounds of the formula (I) wherein ring C, Z, m, n, R1 and R2 are defined herein and salts thereof; their use in the manufacture of a medicament for use in the production of an antiangiogenic and/or vascular permeability reducing effect in warm-blooded animals; processes for the preparation of such compounds; intermediates used in such processes; processes for making such intermediates; pharmaceutical compositions containing a compound of formula I or a pharmaceutically acceptable salt thereof and methods of treating disease states involving angiogenesis by administering a compound of formula I or a pharmaceutically acceptable salt thereof.
Abstract: Spark plug has a central electrode, an insulator provided exterior to the central electrode, main metallic shell provided exterior to the insulator in such a way that the central electrode protrudes from one end, and a ground electrode coupled at one end to the main metallic shell and which has the other end disposed to face the central electrode 3, with a chip being secured to either the central electrode or the ground electrode or both to form spark discharge gap g. The chip is made of a metal based on Ir which contains Rh in an amount ranging from 3 to 50 wt (50 wt % being not inclusive).