Patents Represented by Attorney Myron B. Sokolowski

Find this attorney in the Justia Lawyer Directory

  • 3-Substituted -5-phenyl-5-pyridyl hydantoins
    Patent number: 3994904
    Abstract: Compounds having the generic structure, ##SPC1##And their nontoxic, pharmacologically acceptable salts are useful in the chemotherapy of arrhythmias in individuals for whom such therapy is indicated. In the preceding structural formula: R.sup.1 is a 2-pyridyl, 3-pyridyl, or 4-pyridyl radical; n is an integer of the set 1-3; and R.sup.2 is a hydrogen atom, a hydroxyl, or an equivalent alkoxyl group having from 1 to 3 carbon atoms.
    Type: Grant
    Filed: March 8, 1976
    Date of Patent: November 30, 1976
    Assignee: Miles Laboratories, Inc.
    Inventors: Herbert John Havera, Wallace Glenn Strycker
  • Derivatives of 2-substituted-hydroxyanilino-hexahydro-2H-benzo[.alpha.]quinolizines
    Patent number: 3995041
    Abstract: 2-Substituted-hydroxyanilino-hexahydro-2H-benzo[.alpha.]quinolizines of the structural formula, ##SPC1##In which R.sup.1 is a hydrogen atom or an alkanoyl group of 2 to 4 carbon atoms and each of substituents R.sup.2, R.sup.3, R.sup.4, R.sup.5, and R.sup.6 is a hydrogen atom, a hydroxyl, or a methyl group, such that at least one of the latter substituents is a hydroxyl group, exhibit coronary vasodilating activity.
    Type: Grant
    Filed: October 30, 1975
    Date of Patent: November 30, 1976
    Assignee: Miles Laboratories, Inc.
    Inventors: Herbert John Havera, Richard Don Johnson, Horacio Vidrio
  • Treatment of ethanol withdrawal symptoms with levodopa
    Patent number: 3995058
    Abstract: Levodopa or a composition comprising levodopa and a peripheral dopa decarboxylase inhibitor prevents or suppresses ethanol withdrawal symptoms in individuals abstaining from ethanol in a post-intoxicated state.
    Type: Grant
    Filed: July 28, 1975
    Date of Patent: November 30, 1976
    Assignee: Miles Laboratories, Inc.
    Inventors: Michael Douglas Hammond, Cyril Schneider
  • 11-Substitute d-11-desoxy-pge analogues
    Patent number: 3989744
    Abstract: 11-Substituted-11-desoxy-PGE and -PGF analogues, in which the 11-substituent may be phenyl, (substituted)phenyl, cycloalkyl, spiroalkyl, branched or linear alkyl and alkenyl, and 3-hydroxy-alkenyl, stimulate smooth muscle.
    Type: Grant
    Filed: July 30, 1973
    Date of Patent: November 2, 1976
    Assignee: Miles Laboratories, Inc.
    Inventors: Warren Dexter Woessner, Henry Clifford Arndt, William Gerard Biddlecom, George Peter Peruzzotti, Charles John Sih
  • Phenyl- and (substituted)-phenyl-1,2,3-triazole-alkanoic and -alkenoic acids
    Patent number: 3985765
    Abstract: Certain phenyl- and (substituted)-phenyl-1,2,3-triazole-alkanoic and -alkenoic acids exhibit antiinflammatory or antipyretic activity.
    Type: Grant
    Filed: July 12, 1974
    Date of Patent: October 12, 1976
    Assignee: Miles Laboratories, Inc.
    Inventors: Robert Thomas Buckler, Harold Eugene Hartzler, Shin Hayao
  • 1-(2-Substituted-chromonyloxy)-2-hydroxy-3-(substituted phenoxy)propanes
    Patent number: 3953604
    Abstract: Definitions: in the following Formulae I, II and IV, R.sup.1 represents hydrogen, alkyl of 1 to 4 carbon atoms, or a nontoxic cation, while each of R.sup.2, R.sup.3, R.sup.4, R.sup.5, and R.sup.6 symbolizes hydrogen, alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms, carboxy, carbalkoxy of 1 to 4 carbon atoms, trihalomethyl, halogen, nitro or cyano.Certain 1-(2-substituted-chromon-yloxy)-2-hydroxy-3-(substituted-phenoxy)propanes (Formula I), ##SPC1##can be synthesized from intermediate bis-(substituted-phenoxy)propanes (Formula II), ##SPC2##by condensation with diethyl oxalate in the presence of sodium ethoxide followed by cyclization with a mixture of glacial acetic acid and concentrated sulfuric or a mixture of concentrated hydrochloric acid and a lower alcohol containing up to 4 carbon atoms.
    Type: Grant
    Filed: December 3, 1973
    Date of Patent: April 27, 1976
    Assignee: Miles Laboratories, Inc.
    Inventors: Brian Thomas Warren, John William Spicer
  • Phenyl- and (substituted)-phenyl-1,2,3-triazole-alkanoic and -alkenoic acids
    Patent number: 3948932
    Abstract: Certain phenyl- and (substituted)-phenyl-1,2,3-triazole-alkanoic and -alkenoic acids exhibit antiinflammatory or antipyretic activity.
    Type: Grant
    Filed: October 18, 1974
    Date of Patent: April 6, 1976
    Assignee: Miles Laboratories, Inc.
    Inventors: Robert Thomas Buckler, Harold Eugene Hartzler, Shin Hayao, Gust Nichols
  • Phenyl-and (substituted)-phenyl-1,2,3-triazole-alkanoic and- alkenoic acids
    Patent number: 3948930
    Abstract: Certain phenyl- and (substituted)-phenyl-1,2,3-triazole-alkanoic and -alkenoic acids exhibit antiinflammatory or antipyretic activity.
    Type: Grant
    Filed: July 15, 1974
    Date of Patent: April 6, 1976
    Assignee: Miles Laboratories, Inc.
    Inventors: Robert Thomas Buckler, Harold Eugene Hartzler, Shin Hayao, Gust Nichols
  • Process for the treatment of acne vulgaris utilizing retinal
    Patent number: 3932665
    Abstract: This invention involves the use of retinal in topical therapy of acne vulgaris.
    Type: Grant
    Filed: April 5, 1974
    Date of Patent: January 13, 1976
    Inventors: Eugene J. Van Scott, Ruey J. Yu