Patents Represented by Attorney National Laboratory
  • Patent number: 8344042
    Abstract: The invention provides for a biodegradable synthetic bone composition comprising a biodegradable hydrogel polymer scaffold comprising a plurality of hydrolytically unstable linkages, and an inorganic component; such as a biodegradable poly(hydroxyethylmethacrylate)/hydroxyapatite (pHEMA/HA) hydrogel composite possessing mineral content approximately that of human bone.
    Type: Grant
    Filed: December 8, 2009
    Date of Patent: January 1, 2013
    Assignee: The Regents of the University of California
    Inventors: Gao Liu, Dacheng Zhao, Eduardo Saiz, Antoni P. Tomsia
  • Patent number: 8120448
    Abstract: A tunable nanostructure such as a nanotube is used to make an electromechanical oscillator. The mechanically oscillating nanotube can be provided with inertial clamps in the form of metal beads. The metal beads serve to clamp the nanotube so that the fundamental resonance frequency is in the microwave range, i.e., greater than at least 1 GHz, and up to 4 GHz and beyond. An electric current can be run through the nanotube to cause the metal beads to move along the nanotube and changing the length of the intervening nanotube segments. The oscillator can operate at ambient temperature and in air without significant loss of resonance quality. The nanotube is can be fabricated in a semiconductor style process and the device can be provided with source, drain, and gate electrodes, which may be connected to appropriate circuitry for driving and measuring the oscillation. Novel driving and measuring circuits are also disclosed.
    Type: Grant
    Filed: October 19, 2007
    Date of Patent: February 21, 2012
    Assignee: The Regents of the University of California
    Inventors: Haibing Peng, Alexander K. Zettl
  • Patent number: 8039438
    Abstract: Synthetic peptides derived from sucrose synthase, and having homology to actin and actin-related proteins, sharing a common motif, useful for causing acting bundling and preventing actin depolymerization. Peptides exhibiting the common motif are described, as well as specific synthetic peptides which caused bundled actin and inhibit actin depolymerization. These peptides can be useful for treating a subject suffering from a disease characterized by cells having neoplastic growth, for anti-cancer therapeutics, delivered to subjects solely, or concomitantly or sequentially with other known cancer therapeutics. These peptides can also be used for stabilizing microfilaments in living cells and inhibiting growth of cells.
    Type: Grant
    Filed: October 20, 2004
    Date of Patent: October 18, 2011
    Assignees: The Regents of the University of California, North Carolina State University, U.S. Department of Agricultue/NCAUR
    Inventors: Heike Sederoff, Steven C Huber, Carolyn A Larabell
  • Patent number: 7816055
    Abstract: A novel electrochemical cell which may be a solid oxide fuel cell (SOFC) is disclosed where the cathodes (144, 140) may be exposed to the air and open to the ambient atmosphere without further housing. Current collector (145) extends through a first cathode on one side of a unit and over the unit through the cathode on the other side of the unit and is in electrical contact via lead (146) with housing unit (122 and 124). Electrical insulator (170) prevents electrical contact between two units. Fuel inlet manifold (134) allows fuel to communicate with internal space (138) between the anodes (154 and 156). Electrically insulating members (164 and 166) prevent the current collector from being in electrical contact with the anode.
    Type: Grant
    Filed: March 16, 2005
    Date of Patent: October 19, 2010
    Assignee: The Regents of the University of California
    Inventors: Craig Jacobson, Lutgard C. DeJonghe, Chun Lu
  • Patent number: 7483509
    Abstract: A method and a system for detecting the presence of special nuclear materials in a suspect container. The system and its method include irradiating the suspect container with a beam of neutrons, so as to induce a thermal fission in a portion of the special nuclear materials, detecting the gamma rays that are emitted from the fission products formed by the thermal fission, to produce a detector signal, comparing the detector signal with a threshold value to form a comparison, and detecting the presence of the special nuclear materials using the comparison.
    Type: Grant
    Filed: October 12, 2007
    Date of Patent: January 27, 2009
    Assignee: The Regents of the University of California
    Inventors: Eric B. Norman, Stanley G. Prussin
  • Patent number: 7474725
    Abstract: A method and a system for detecting the presence of special nuclear materials in a suspect container. The system and its method include irradiating the suspect container with a beam of neutrons, so as to induce a thermal fission in a portion of the special nuclear materials, detecting the gamma rays that are emitted from the fission products formed by the thermal fission, to produce a detector signal, comparing the detector signal with a threshold value to form a comparison, and detecting the presence of the special nuclear materials using the comparison.
    Type: Grant
    Filed: October 12, 2007
    Date of Patent: January 6, 2009
    Assignee: The Regents of the University of California
    Inventors: Eric B. Norman, Stanley G. Prussin
  • Patent number: 7277521
    Abstract: A method and a system for detecting the presence of special nuclear materials in a container. The system and its method include irradiating the container with an energetic beam, so as to induce a fission in the special nuclear materials, detecting the gamma rays that are emitted from the fission products formed by the fission, to produce a detector signal, comparing the detector signal with a threshold value to form a comparison, and detecting the presence of the special nuclear materials using the comparison.
    Type: Grant
    Filed: April 8, 2004
    Date of Patent: October 2, 2007
    Assignee: The Regents of the University of California
    Inventors: Eric B. Norman, Stanley G. Prussin
  • Patent number: 7261871
    Abstract: A simple method for the production or synthesis of carbon nanotubes as free-standing films or nanotube mats by the thermal decomposition of transition metal complexed alkynes with aryl, alkyl, alkenyl, or alkynyl substituents. In particular, transition metal (e.g. Co, Ni, Fe, Mo) complexes of diarylacetylenes, e.g. diphenylacetylene, and solid mixtures of these complexes with suitable, additional carbon sources are heated in a vessel. More specifically, the heating of the transition metal complex is completed at a temperature between 400-800° C. and more particularly 550-700° C. for between 0.1 to 24 hours and more particularly 0.5-3 hours in a sealed vessel under a partial pressure of argon or helium.
    Type: Grant
    Filed: September 30, 2002
    Date of Patent: August 28, 2007
    Assignee: The Regents of the University of California
    Inventors: Vivekanantan S. Iyer, K. Peter C. Vollhardt
  • Patent number: 7136757
    Abstract: A method for identifying, imaging and monitoring dry or fluid-saturated underground reservoirs using seismic waves reflected from target porous or fractured layers is set forth. Seismic imaging the porous or fractured layer occurs by low pass filtering of the windowed reflections from the target porous or fractured layers leaving frequencies below low-most corner (or full width at half maximum) of a recorded frequency spectra. Additionally, the ratio of image amplitudes is shown to be approximately proportional to reservoir permeability, viscosity of fluid, and the fluid saturation of the porous or fractured layers.
    Type: Grant
    Filed: May 2, 2005
    Date of Patent: November 14, 2006
    Assignee: The Regents of the University of California
    Inventors: Gennady M. Goloshubin, Valeri A. Korneev
  • Patent number: 7126139
    Abstract: A device and a method for positionally accurate implantation of individual particles in a substrate surface (1a) are described. A diaphragm for a particle beam to be directed onto the substrate surface (1a) and a detector provided thereon in the form of a p-n junction for determining a secondary electron flow produced upon impact of a particle onto the substrate surface (1a) are provided on a tip (4) which is formed on a free end portion of a flexible arm (2) to be mounted on one side. The device is part of a scanning device operating according to the AFM method.
    Type: Grant
    Filed: October 9, 2003
    Date of Patent: October 24, 2006
    Assignee: The Regents of the University of California
    Inventors: Thomas Schenkel, Ivo W. Rangelow, Jan Meijer
  • Patent number: 6984369
    Abstract: Disclosed is a process for making surfactant capped nanocrystals of metal oxides which are dispersable in organic solvents. The process comprises decomposing a metal cupferron complex of the formula MXCupX, wherein M is a metal, and Cup is a N-substituted N-Nitroso hydroxylamine, in the presence of a coordinating surfactant, the reaction being conducted at a temperature ranging from about 150 to about 400° C., for a period of time sufficient to complete the reaction. Also disclosed are compounds made by the process.
    Type: Grant
    Filed: November 22, 2000
    Date of Patent: January 10, 2006
    Assignee: The Regents of the University of California
    Inventors: A. Paul Alivisatos, Joerg Rockenberger