Patents Represented by Attorney Needle & Rosenberg, PC.
  • Patent number: 7427671
    Abstract: A DNA sequence which encodes a human type ? platelet derived growth factor receptor protein which preferentially binds to the AA homodimer and AB heterodimer forms of platelet derived growth factor and also binds the BB homodimer at high affinity, is described. Substantially pure human a platelet derived growth factor receptor protein and methods for recombinantly producing human ? platelet derived growth factor receptor protein are also described.
    Type: Grant
    Filed: May 11, 1995
    Date of Patent: September 23, 2008
    Assignee: The United States of America as represented by the Secretary, Department of Health and Human Services
    Inventors: Toshimitsu Matsui, Stuart A. Aaronson, Jacalyn H. Pierce
  • Patent number: 7393666
    Abstract: Novel methods of regulating cellular apoptosis by affecting the interaction of hepatitis B X-interacting protein (HBXIP) with Survivin are described. More specifically, these novel methods of enhancing apoptosis of neoplastic cells comprises inhibiting interaction of hepatitis B X-interacting protein (HBXIP) with Survivin.
    Type: Grant
    Filed: May 24, 2006
    Date of Patent: July 1, 2008
    Assignee: Burnham Institute for Medical Research
    Inventors: Ingo Tamm, John C. Reed
  • Patent number: 7368540
    Abstract: The present invention relates to the field of GABA receptor structure and function. In one aspect, the present invention relates to impairment of the gamma-aminobutyric acid (GABA) receptors in parasitic nematodes, for the purpose of crop protection and/or soil treatment. The invention includes mutated nematode GABA receptor subunits, nematode GABA neuromuscular junction receptor complexes, nucleic acids which encode the mutated and functional receptor complexes, antibodies which selectively bind the GABA receptor complexes and/or subunits, and assays for compounds which adversely affect nematode GABA neuromuscular junction receptor function. The present invention therefore relates broadly to recombinant DNA technology, molecular biology tools, and crop protection and/or soil treatment.
    Type: Grant
    Filed: September 30, 2005
    Date of Patent: May 6, 2008
    Assignee: University of Utah Research Foundation
    Inventors: Bruce A. Bamber, Erik M. Jorgensen
  • Patent number: 7364517
    Abstract: A soccer practice apparatus to assist a user in practicing the ability to power kick, ball control, mid-volley and/or head a soccer ball. The apparatus can be formed from an arm assembly comprised of a primary arm member angled with a smooth bend to a substantially vertical portion at the end. The arm assembly is connected to a substantially vertical support member. A tether cord extends through and along a length of the primary arm member and is attached to a soccer ball. The tether cord is adjustable and permits the height of the ball to be adjusted for ground ball positions, mid volleys, and heading. The apparatus further permits a ball to be hit in any direction from any adjusted position above ground without creating ball contact with the upright support member.
    Type: Grant
    Filed: October 7, 2005
    Date of Patent: April 29, 2008
    Inventor: Brian Peter Johnsen
  • Patent number: 7361502
    Abstract: The present invention relates to a gene and the coded protein thereof that is involved in the development of sequelae of local ischaemia. The new protein is a serine threonine protein kinase and provides a new therapeutic approach to the prophylaxis and therapy of apoplexy.
    Type: Grant
    Filed: May 17, 2001
    Date of Patent: April 22, 2008
    Assignee: SYGNIS Bioscience GmbH & Co. KG
    Inventors: Armin Schneider, Bettina Klaussner, Achim Fischer, Dieter Newrzella, Bernhard Götz, Moritz Rossner, Gisela Eisenhardt, Rohini Kuner, Annette Trutzel, Birgitta Kammandel, Stephanie Jomana Naim, Markus Schwaninger
  • Patent number: 7357971
    Abstract: The present invention pertains to carpet and methods of making carpet. In one aspect, the carpet includes (a) a primary backing which has a face and a back surface, (b) a plurality of fibers attached to the primary backing and extending from the face of the primary backing and exposed at the back surface of the primary backing, (c) an adhesive backing, (d) an optional secondary backing adjacent to the adhesive backing, and (e) at least one homogeneously branched ethylene polymer. The method includes extrusion coating at least one homogeneously branched ethylene polymer onto the back surface of a primary backing to provide an adhesive backing. The method can include additional steps or procedures, either separately or in various combinations. Additional steps and procedures include washing or scouring the primary backing and fibers prior to the extrusion step, and utilizing implosion agents. The preferred homogeneously branched ethylene polymer is a substantially linear ethylene polymer.
    Type: Grant
    Filed: July 29, 2005
    Date of Patent: April 15, 2008
    Assignee: Columbia Insurance Company
    Inventors: John O. Bieser, Joseph A. Dibbern, Charles F. Diehl, James D. Goins, David C. Kelley, Rexford A. Maugans, Osborne K. McKinney, Lichih R. Peng, Robert R. Turley
  • Patent number: 7347920
    Abstract: Lightweight and reactive metals can be produced from ore, refined from alloy, and recycled from metal matrix composites using electrolysis in electrolytes including an ionic liquid containing a metal chloride at or near room temperature. Low electric energy consumption and pollutant emission, easy operation and low production costs are achieved.
    Type: Grant
    Filed: July 12, 2004
    Date of Patent: March 25, 2008
    Assignee: The Board of Trustees of the University of Alabama
    Inventors: Banqiu Wu, Ramana G. Reddy, Robin D. Rogers
  • Patent number: 7345031
    Abstract: Hydrophilic transportable N-linked glycosyl dopaminergic prodrug compounds according to FORMULA V and methods of their use, wherein, Ring 1 comprises an aryl or heteroaryl ring having 4 to 8 carbon atoms, among which atoms are counted “X” and “Y”; each of X and Y is optional; X, when present is either —C(R1)2— or —C(R1)2—; Y, when present, is either —CH2— or —CH2—CH2—; z, R5 and R5? are optional, and when present z, R5 and R5? together form a lower alkyl or a substituted lower alkyl moiety; N is part of either an amine or an amide linkage; E is a saccharide which forms a linkage with N through a single bond from a carbon or oxygen atom thereof; R1 and R4 are selected form the group consisting of hydrogen, hydroxyl, halogen, halo-lower alkyl, alkoxyl, alkoxyl-lower alkyl, halo-alkoxy, thioamido, amidosulfonyl, alkoxylcarbonyl, carboxamide, aminocarbonyl, and alkylamino-carbonyl; R2 and R3 are hydroxyl; R5 and R6, when present, are selected from the group consisting of hydrogen, hydroxyl, alkoxyl, carbon
    Type: Grant
    Filed: July 22, 2003
    Date of Patent: March 18, 2008
    Assignee: International Medical Innovations, Inc.
    Inventor: Samuel T. Christian
  • Patent number: 7338698
    Abstract: The present invention pertains to carpet and methods of making carpet. In one aspect, the carpet includes (a) a primary backing which has a face and a back surface, (b) a plurality of fibers attached to the primary backing and extending from the face of the primary backing and exposed at the back surface of the primary backing, (c) an adhesive backing, (d) an optional secondary backing adjacent to the adhesive backing, and (e) at least one homogeneously branched ethylene polymer. The method includes extrusion coating at least one homogeneously branched ethylene polymer onto the back surface of a primary backing to provide an adhesive backing. The method can include additional steps or procedures, either separately or in various combinations. Additional steps and procedures include washing or scouring the primary backing and fibers prior to the extrusion step, and utilizing implosion agents. The preferred homogeneously branched ethylene polymer is a substantially linear ethylene polymer.
    Type: Grant
    Filed: February 27, 1998
    Date of Patent: March 4, 2008
    Assignee: Columbia Insurance Company
    Inventors: John O. Bieser, Lichih R. Peng
  • Patent number: 7279462
    Abstract: The invention provides a method for stimulating an immune response by administering to a lymphoid tissue a nucleic acid molecule comprising an expression element operationally linked to a nucleic acid sequence encoding one or more heterologous epitopes. The heterologous epitope can be inserted into a complementarity-determining region of an immunoglobulin molecule. The invention also provides a nucleic acid molecule comprising a hematopoietic expression element operationally linked to a nucleic acid sequence encoding a heterologous polypeptide. The invention additionally provides a method of treating a condition by administering a nucleic acid molecule comprising a hematopoietic cell expression element operationally linked to a nucleic acid sequence encoding a heterologous polypeptide, wherein the nucleic acid molecule is targeted to a hematopoietic cell.
    Type: Grant
    Filed: April 27, 1999
    Date of Patent: October 9, 2007
    Assignee: Nevagen LLC
    Inventor: Maurizio Zanetti
  • Patent number: 7279171
    Abstract: Vaccine compositions protective against Chlamydia psittaci infections in animals, including but not limited to humans and avian species, comprising an immunogenic amount of a C. psittaci major outer membrane protein (MOMP) polypeptide lacking regions VD1 and VD2 are provided. Nucleic acid vectors for the expression of MOMP polypeptides and MOMP polypeptide fusion proteins are disclosed. Nucleic acid vectors encoding a C. psittaci major outer membrane protein (MOMP) polypeptide lacking regions VD1 and VD2 useful for genetic, or “naked nucleic acid” vaccination are disclosed. Methods for preventing a Chlamydia psittaci infection in a subject using MOMP polypeptides, MOMP polypeptide-fusion proteins, or nucleic acid expression vectors are also provided.
    Type: Grant
    Filed: August 11, 2003
    Date of Patent: October 9, 2007
    Assignee: Board of Supervisors of Louisiana State University and Mechanical College
    Inventors: Konstantin G. Kousoulas, Vladimir N. Chouljenko, Abolgasem Baghian, Thomas N. Tully, Jr.
  • Patent number: 7265856
    Abstract: A system and method for transmitting multiple data streams from a host to a printing device. Data streams are arranged according to color, segmented and compressed, if desired. If compression is used, each segment may compressed with a different compression algorithm. Each segment contains a header describing the size of the data in the segment. The host transmits a print header containing information and instructions necessary for the print device to reassemble and process the data segments to produce a printed item.
    Type: Grant
    Filed: March 21, 2001
    Date of Patent: September 4, 2007
    Assignee: Lexmark International Inc.
    Inventors: Heather Laudan Clark, Duane Edward Norris
  • Patent number: 7252929
    Abstract: Discoveries are disclosed that show particular aspects of recombinant DNA technology can be used successfully to produce a hitherto unknown type of human Platelet-Derived Growth Factor (PDGF) receptor protein free of other PDGF receptors. These proteins can be produced from DNA segments in cells in various functional forms. These forms variously enable biochemical and functional studies of these novel receptors as well as production of antibodies. Means are described for determining the level of expression of genes for specific types of PDGF receptor proteins, for example, by measuring mRNA in cells with PDGF receptor type-specific DNA probes or by measuring antigen in biological samples with type-specific antibodies.
    Type: Grant
    Filed: November 3, 2003
    Date of Patent: August 7, 2007
    Assignee: United States of America, as represented by the Secretary, Dept of Health & Human Services
    Inventors: Toshimitsu Matsui, Stuart A. Aaronson, Jacalyn H. Pierce
  • Patent number: 7237505
    Abstract: The present invention relates to the field of avian reproduction. In particular, the present invention provides a method of activating an egg in a shell. The invention also provides a method of activating an egg in a shell, whereby a live chick is hatched.
    Type: Grant
    Filed: February 15, 2001
    Date of Patent: July 3, 2007
    Assignee: Ovo Biosciences, Inc.
    Inventors: Tim Cantrell, Andrew Wooten
  • Patent number: 7223535
    Abstract: Synthetic peptides immunoreactive with hepatitis A virus (HAV) antibodies are provided. The peptides are useful as laboratory reagents to detect or quantify HAV antibodies in biological samples in clinical or research-based assays and for inducing an immune response to HAV when administered to a human or animal. The peptides contain antigenic epitopes, modified antigenic epitopes or combinations of epitopes of the major structural capsid polypeptides or non-structural polypeptides of HAV and contain one or more molecules of the amino acid glutamine (Q) at the carboxyl end of the peptide, which enhances immunoreactivity and immunogenicity, particularly IgM antibody reactivity.
    Type: Grant
    Filed: December 16, 2003
    Date of Patent: May 29, 2007
    Assignee: Centers for Disease Control
    Inventors: Howard A. Fields, Yury E. Khudyakov
  • Patent number: 7225080
    Abstract: The present invention is drawn to a new diagnosis method for detecting the extend of a inflammatory, fibrotic or cancerous disease in a patient, in particular liver fibrosis, in particular in a patient infected with hepatitis C virus, by using the serum concentration of easily detectable biological markers. The invention is also drawn to diagnosis kits for the implementation of the method.
    Type: Grant
    Filed: August 27, 2003
    Date of Patent: May 29, 2007
    Assignee: Assistance Publique-Hopitaux de Paris (AP-HP)
    Inventor: Thierry Poynard
  • Patent number: 7217269
    Abstract: An electrosurgical control system includes a selector by which a user can select any of a number of electrosurgical devices or similar devices for use, and a processor system responsive to user actuation of a foot control or other central control by controlling the selected device. Each device has an associated intelligent adapter that communicates information relating to device with which the adapter is associated. The processor system uses the information communicated by the adapter to properly interface the associated device with the control system and its central control.
    Type: Grant
    Filed: October 28, 2004
    Date of Patent: May 15, 2007
    Assignee: UAB Research Foundation
    Inventors: Rizk El-Galley, David Austin Alexander, Mary Hawn
  • Patent number: 7199162
    Abstract: The invention relates to the use of treosulfan as a conditioning agent before allogenic transplantation of bone marrow or haematopoietic stem cells, whereby treosulfan is administered, either as single effective agent, or in combination with other chemotherapetic agents or immunosuppressant agents.
    Type: Grant
    Filed: November 3, 2000
    Date of Patent: April 3, 2007
    Assignee: Medac Gesellschaft fur Klinische Spezialpraparate mbH
    Inventor: Joachim Baumgart
  • Patent number: 7179640
    Abstract: The present invention provides antibodies which specifically bind early conception factor, which can be found in body fluids of animals including but not limited to the cow, cat, dog, horse, human, sheep, and pig. The invention provides methods for detecting conception or the absence of conception in an animal, the latter being recognized by the absence of early conception factor in a suitable body fluid collected from the animal. Apparati for detecting early conception factor in a body fluid from an animal comprising the antibodies which specifically bind early conception factor are also provided.
    Type: Grant
    Filed: January 6, 2006
    Date of Patent: February 20, 2007
    Assignee: EDP Biotech Corporation
    Inventors: Nancy Tommye Jordan, John Douglas Jordan
  • Patent number: D545483
    Type: Grant
    Filed: October 21, 2004
    Date of Patent: June 26, 2007
    Assignee: Acuity Brands, Inc.
    Inventors: John T. Mayfield, III, Carl T. Gould, Kevin Leadford, Stephen H. Lydecker