Abstract: An analytical apparatus comprises a biosensor device (3) which forms the base of a sample chamber. A stirrer (8) extends into the sample chamber and moves within the chamber so as to homogenize a sample contained within the chamber in contact with the biosensor (3). Movement of the stirrer (8) is preferably reciprocal movement along an axis perpendicular to the surface of the biosensor (3).

Abstract: A process for capture, degradation, and destruction of a sulfur bearing compound that satisfies the needs for a treatment process that may be used in cartridge, pipeline, and batch, that can handle a large variety of sulfur bearing environmental pollutants, is faster than other methods, and that does not leave dangerous degradation product fractions and residuals in wastewater from the treatment process itself. The present invention is further directed towards a treatment process that is capable of using a safe, dry storable cartridge with small amounts of dry storable mixed resins in a small cartridge, that can fit into a "point of use" pipeline from a contaminated well or point of contaminated "run-off". Dangerous degradation product fractions and residuals in wastewater, are minimized, in order to minimize residual environmental impacts from the treatment process itself. Sulfur bearing compounds are mixed with metals insoluble with the sulfur bearing compounds, reducing agents, and bases.

Abstract: The present invention relates to methods for treating cocaine and amphetamine dependency. The method involves administering to the patient an effective amount of a compound having the formula: ##STR1## wherein R.sup.1 is selected from the group consisting of hydrogen and C1 to C6 alkyl;R.sup.2 is selected from the group consisting of hydrogen, methyl, and ethyl;R.sup.3 is selected from the group consisting of hydrogen, methyl, C1 to C6 alkanoyl, C3 to C6 cycloalkanoyl, and pyridinecarbonyl;Q is a bivalent alkylene moiety; andY is selected from the group consisting of a halo-(C2 to C6)-alkenyl moiety having 1 or 2 chlorine or bromine atoms attached to the ethylenic carbon, a cycloalkyl moiety, a cyano moiety, and a cyano-(C3 to C6)-alkenyl moietyor a pharmaceutically acceptable acid-addition salt thereof. Discomforting side effects can be minimized by optionally administering naltrexone, naloxone, or a mixture thereof during the early phases of treatment.

Abstract: A journal bearing assembly for mounting within a rotatable shaft that has been hollowed out to form a shaft cavity, said assembly comprising a plurality of bearing pads positioned about a bearing support, said support and bearing pads positioned within the hollowed out shaft end, said bearing pads then positioned between the bearing support and the shaft cavity wall.

Abstract: A test device for detecting or quantifying an analyte in a test sample includes an absorbent material having separate contact and measurement portions. The contact portion is positioned at or proximate to a first end of the absorbent material. The measurement portion has a receptor for a conjugate of an analyte analog and marker-encapsulating liposomes. In a method for using the test device, a binding material specific for the analyte is combined with the liposome-analyte analog conjugate and the test sample to form a test mixture. The mixture is incubated for a time sufficient to permit competition between any analyte present and the conjugate for the binding material. Following incubation, the mixture is allowed to traverse the absorbent material from the contact portion through the measurement portion of the absorbent material.

Abstract: A test device for detecting or quantifying an analyte in a test sample includes an absorbent material having separate contact and measurement portions. The contact portion is positioned at or proximate to a first end of the absorbent material. The measurement portion has a receptor for a conjugate of an analyte analog and marker-encapsulating liposomes. In a method for using the test device, a binding material specific for the analyte is combined with the liposome-analyte analog conjugate and the test sample to form a test mixture. The mixture is incubated for a time sufficient to permit competition between any analyte present and the conjugate for the binding material. Following incubating, the mixture is allowed to traverse the absorbent material from the contact portion through the measurement portion of the absorbent material.

Abstract: The present invention relates to a process for preparation of substantially pure piperidine derivative compounds of the formulae: ##STR1## wherein R.sub.1 is hydrogen or hydroxy;R.sub.2 is hydrogen;or R.sub.1 and R.sub.2 taken together form a second bond between the carbon atoms bearing R.sub.1 and R.sub.2 ;R.sub.3 is --COOH or --COOR.sub.4 ;R.sub.4 has 1 to 6 carbon atoms;A, B, and D are the substituents of their respective rings each of which may be different or the same and are hydrogen, halogens, alkyl, hydroxy, alkoxy, or other substituents.

Abstract: The present invention relates to a method for chemically modifying a reactant using microbes. The method includes providing a particulate material which includes a plastic carrier and microbes attached to the carrier. The particulate material is dispersed in a dispersing fluid and has a specific gravity less than that of the dispersing fluid. When the microbe is anaerobic the particulate material has an operating interfacial surface area of from about 2,000 to about 240,000 square meters per cubic meter of reactor volume. When the microbe is aerobic the particulate material has an operating interfacial surface area of from about 1,000 to about 30,000 square meters per cubic meter of reactor volume. The method further includes establishing a flow of the reactant through the particulate material effective to contact the reactant with the microbes for a time sufficient to chemically modify the reactant. Use of the methods in wastewater treatment, aquaculture fish production, and ethanol production are disclosed.

Abstract: A single celled organism, vector, and method are provided for continuous production of excreted proteins in the absence of substantial host cell replication and without the necessity for the addition of antibiotics to control cell replication. The vector has (1) an inducible promoter capable of activating a gene for a protein to be produced under conditions that substantially inhibit host cell replication, and (2) a hybrid gene containing a signal sequence fused to a gene for the protein to be produced. Large quantities of the transformed single celled organisms containing the vector can be grown in the absence of inducing conditions, thereby reducing the problem of plasmid loss. Further, the protein is produced under conditions that substantially inhibit host cell replication, thereby allowing immobilization of the single celled organism by entrapment or attachment within or onto a solid support surface. The single celled organism can be immobilized after, before or simultaneously with induction.

Abstract: The present invention is directed to an isolated bacteriophage designated .phi.CPG1. The invention is further directed to an isolated DNA molecule encoding bacteriophage .phi.CPG1, or a fragment thereof, a DNA molecule comprising DNA encoding bacteriophage .phi.CPG1 with heterologous DNA inserted therein, or a fragment thereof, and to oligonucleotides consisting essentially of a portion of the DNA molecule encoding .phi.CPG1. The bacteriophage .phi.CPG1 was isolated from Chlamydia psittaci strain Guinea Pig inclusion Conjunctivitis.

Abstract: An acceptor material for printing by ink-jet primers forms water-resistant, light-stable ink records with aqueous ink jet inks. The material comprises a support such as polyester film and a coating containing a water-soluble phospholipid mordant that forms insoluble compounds with and immobilizes the dyestuffs of the ink jet inks and a water managing polymer, preferably, hardened gelatin, which quickly renders the material dry-to-the-touch after contact with the aqueous ink.

Abstract: An adapter for use with an apparatus for the control of human lactation. The apparatus comprising a support having an outer surface and an inner surface that is shaped to conform substantially to a human female breast and having a protrusion which extends away from the support and is positioned to align substantially with a nipple of a human female. The adapter comprises an attachment having a second outer surface and a second inner surface. The second outer surface has a second protrusion extending away from the second outer surface and is shaped to fit over the first protrusion. The second inner surface is positioned to align substantially with and contact a nipple of the human female breast to prevent the human female breast from lactating when the apparatus with the adapter is placed over the human female breast.

Abstract: The present invention is directed to a vector for transferring heterologous DNA into a plant cell. The vector is based on the bacterial artificial chromosome (BAC) vector designed for the construction of genomic libraries with large DNA inserts, and the binary (BIN) vector designed for Agrobacterium-mediated plant transformation. The BIBAC vector according to the subject invention allows the construction of plant genomic libraries with large DNA inserts that can be directly introduced into plants by transformation mediated by Agrobacterium.

Abstract: A compound having the structural formula, ##STR1## where R.sup.1 and R.sup.2 are independently hydrogen or hydroxyl. R.sup.2 and R.sup.3 are independently oxo or hydrogen, one of R.sup.5 and R.sup.6 is A--B and the other is hydrogen, hydroxyl, or a group A, wherein each A is a spacer group providing --NH-- or --CO-- in the bond with B (if present); at least one A group does not provide the residue of an .alpha.-amino acid adjacent the anthraquinone nucleus and the A of any A--B moiety is joined to the anthraquinone nucleus via an --NH-- bond, and each B is a peptide group or a physiologically acceptable derivative thereof. The compounds are useful as antitumor compounds.

Abstract: The present invention relates to an isolated DNA molecule encoding a cytochrome P450.sub.lpr polypeptide as well as the isolated cytochrome P450.sub.lpr polypeptide itself. The DNA molecule can be inserted as a heterologous DNA in an expression vector forming a recombinant DNA expression system for producing the polypeptide. Likewise, the heterologous DNA, usually inserted in an expression vector to form a recombinant DNA expression system, can be incorporated in a host cell to achieve this objective.The DNA molecule of the present invention can be utilized for control of larval or adult insects, bioremediation of insecticides, and conferring pesticide resistance to crop plants.

Abstract: A method for inhibiting corrosion of a substrate by applying to a substrate a corrosion resistant coating comprising a diamond-like solid state material having interpenetrating atomic scale networks of class of diamond-like solid state materials formed from interpenetrating networks comprising a first network of carbon in a diamond-like carbon network stabilized by hydrogen, a silicon network stabilized by oxygen, and optionally at least one network made from dopant elements or dopant compounds containing elements from groups 1-7b and 8 of the periodic table.

Abstract: The present invention is directed to compounds useful as moth attractants and to methods for controlling populations of the tomato moth Scrobipalpuloides absoluta with these compounds. The compounds are 3,8,11-tetradecatrienyl acetates, 3,8-tetradecadienyl acetates, 3,11-tetradecadienyl acetates, and 8,11-tetradecadienyl acetates. Preferred compounds are (3E,8Z,11Z)-3,8,11-tetradecatrienyl acetate, (3E,8Z)-3,8-tetradecadienyl acetate, (3E,11Z)-3,11 -tetradecadienyl acetate, and (8Z,11Z)-8-11-tetradecadienyl acetate. The compounds can be used as an attractant in moth traps comprising, in addition to the compounds, a moth restraint. Alternatively, the compounds of the present invention can be combined with a biocontrol agent or an insecticide for use as a moth control composition. Synthesis of (3E,8Z,11Z)-3,8,11-tetradecatrienyl acetate is described.

Abstract: A tilting bearing pad for use in a turbine engine in accordance with the present invention includes an opening extending between opposing inner and outer surfaces of the pad and a profiled area extending from the opening. More specifically, the opening comprises a feed hole which extends from the outer surface toward the inner surface of the pad and is connected to an axial feed groove which extends to and along the inner surface. The profiled area extends from one side of the axial feed groove towards the trailing edge of the bearing pad along the inner surface. The side of the profiled area facing the trailing edge of the pad may be squared or tapered. The side of the axial feed groove facing the leading edge remains substantially flush with the groove and does not extend towards the leading edge. A turbine engine with the tilting bearing pad as described above also includes two bearing cases, a rotor, and a fluid supply system. The bearing cases are located at opposing ends of the turbine case.

Abstract: An erosion resistant coating for optically transmissive substrates formed from a diamond-like nanocomposite structure which contains interpenetrating networks of a diamond-like carbon matrix stabilized by hydrogen, a silicone glass-like network stabilized by oxygen, and optionally, at least one network formed from elements and compounds from groups 1-7b and 8 of the periodic table.

Abstract: The present invention provides novel hydrogel-forming, self-solvating, absorbable polyester copolymers capable of selective, segmental association into compliant hydrogels upon contacting an aqueous environment.