Abstract: This invention relates to new N-acylpeptide compounds of immunological activity, said compounds being of the formula: ##EQU1## wherein R.sup.1 and R.sup.2 are each alkyl or alkenyl;R.sup.3 is hydrogen, lower alkyl, hydroxy(lower)alkyl, heterocyclic(lower)alkyl or ar(lower)alkyl, wherein the aryl moiety may have hydroxy or protected hydroxy;R.sup.4 is carboxy, esterified carboxy, carboxy(lower)alkyl or esterified carboxy(lower)alkyl;X is bond or lower alkylene;Y is lower alkylene or lower alkylidene; andn is an integer of 0 to 1;or its pharmaceutically acceptable salt.

Abstract: Apatite is conventionally made into a fertilizer material by treatment with a strong acid, requiring capital-intensive industry. Hydroxyapatite is treated above 1100.degree. C. with alkali but world reserves are problematic. The invention treats apatite at 900.degree. C. with sodium aluminosilicate/carbonate and siliceous material in quantities to keep the composition in terms of CaO, SiO.sub.2, Na.sub.2 O and P.sub.2 O.sub.5 in or near the ternary system Ca.sub.2 SiO.sub.4 --Ca.sub.3 (PO.sub.4).sub.2 --CaNaPO.sub.4.

Abstract: The device for controlling a local clock signal H both in frequency and in phase by means of a binary signal S comprises logical means for delivering two signals S.sub.1 and S.sub.3 representing respectively the sign of the phase difference and the sign of the frequency difference between the signals H and S. The signal H is generated by a voltage-controlled oscillator circuit, the control voltage of which is generated by a tuning control circuit as a function of the signal S.sub.1 when the frequency of the signal H is close in value to the desired frequency and as a function of the signal S.sub.3 when this is not the case.

Abstract: Addition compounds have the formula ##STR1## wherein R.sub.1 represents an aliphatic oxycarbonyl group, benzyloxycarbonyl group which can have nuclear substituents or benzoyl, aromatic sulfonyl or aromatic sulfinyl group; R.sub.2 represents methyl, isopropyl, isobutyl, isoamyl or benzyl group; R.sub.3 represents a lower alkoxyl, benzyloxy or benzhydryloxy group and n represents 1 or 2.The addition compounds are produced by reacting an N-substituted monoaminodicarboxylic acid having the formula ##STR2## with an amino carboxlic acid ester having the formula in an aqueous medium in the presence of a protease and reacting the resulting dipeptide ester with the amino carboxylic acid ester and separating the addition compound.The addition compounds can be decomposed into the constituent dipeptide esters and amino acid esters by the action of an acid.

Abstract: A 1-(4-aminobenzyl)-2,3-dioxopiperazine derivative represented by the formula: ##STR1## and an acid addition salt thereof have excellent carcinostatic activity but a low toxicity. Therefore, said compounds are useful as medicines and also as intermediates.

Abstract: A physiologically active novel substance designated as Mutastein is disclosed, which has the following specific physiological properties:(1) it has a molecular weight of at least 200,000, and when subjected to gel-filtration with Sephadex G-100 and Sephallose 6B, it will be eluted in the void volume;(2) its ultraviolet spectrum: FIG. 1;(3) its infrared spectrum: FIG. 2;(4) it has a proteinous nature and contains about 10% of saccharide;(5) it is soluble in water and a saline solution, but it will be salted out from a saturated solution containing about 30% of ammonium salfate; and it is insoluble in acetone, ethanol, ethylacetate and benzene,(6) it dissolves in a buffer solution having a pH 7 or over, but it precipitates at a pH of from 3 to 3.5,(7) it is stable when heat-treated at pH 9, at 100.degree. C. for 10 minutes,(8) its elementary analysis: C: about 44%, H: about 7%, and N: about 12%,(9) its color reactions: Phenol-surfuric acid color reaction (orange), and Folin's color reaction (blue).

Abstract: An anticorrosive coating process comprises:(i) a step of applying on a substrate a zinc-rich paint or an epoxy resin primer coating, followed by air-drying,(ii) a step of applying thereon an intermediate synthetic resin coating, followed by air-drying, and(iii) a step of applying thereon a top coating comprising (a) a fluorine-containing copolymer composed of from 40 to 60 molar % of a fluoroolefin, from 5 to 45 molar % of cyclohexylvinyl ether, from 5 to 45 molar % of an alkylvinyl ether, from 3 to 15 molar % of a hydroxyalkylvinyl ether and from 0 to 30 molar % of other comonomer and (b) a polyisocyanate, followed by air-drying.

Abstract: Salts of polymaleic acids, having molecular weights of from 200 to 1,500, with amines, of the formula ##STR1## where R.sup.1 and R.sup.2 are identical or different and each is hydrogen, C.sub.9 -C.sub.20 -alkyl or C.sub.9 -C.sub.20 -alkenyl and R.sup.3 is C.sub.9 -C.sub.20 -alkyl or C.sub.9 -C.sub.20 -alkenyl.

Abstract: A vertical axis windmill has a blade pivotally connected to a rotatable support structure on an axis passing through its center of gravity which is arranged to lie forward of its aerodynamic center whereby the blade automatically swings outwardly and inwardly when moving on the windward and leeward sides respectively of the axis of rotation of said support means.

Abstract: A low-pressure screw in-line type injection molding method and apparatus for use with materials such as urea mixed resin powder are disclosed. The initial injection is performed at a converted injection pressure in the range of 250-700 Kg/cm.sup.2 and at an injection velocity in the range of 30-50 mm/sec. When the mold cavity has become nearly completely filled, the converted injection pressure is lowered to 50-200 Kg/cm.sup.2 for the completion of the injection cycle under low pressure conditions.

Abstract: A method of manufacturing metal pieces by casting and sintering of a metal alloy powder of the type that includes two phases, a conforming phase during which a load of powder is heated inside a formal casting to execute a rigid preform which is porous and a compacting and sintering phase during which the preform is heated under isostatic pressure. The method and resulting metal piece is characterized in that the conforming phase is conducted so that the preform has open pores and the isostatic pressure is applied by way of an envelope that distorts and is airtight. The method is applied advantageously in the execution of complex formal pieces made of superalloys or made of a titanium alloy.

Abstract: A gasket is disclosed having a lining (3) with watertight rims (4,5,8) in which lining is placed between two rings (2,6). A rim (8), which interlocks with the lining (3) attached to one of the rings (2 or 6), rests on the edge (7) of the other ring (6 or 2) so as to keep the two rings together while enclosing the lining.

Abstract: Crude 2-methyleneglutaronitrile containing as impurities a metal halide, a trialkylamine, and the trimer or a higher polymer of acrylonitrile can be effectively purified by treating the crude 2-methyleneglutaronitrile with hydrochloric acid, sulfuric acid or nitric acid of a concentration of 1 to 30% by weight and then subjecting the treated methyleneglutaronitrile to vacuum distillation.

Abstract: An electric furnace including a furnace vessel having modular thermally stressed wall parts, wherein in order to lengthen the service life of the thermally stressed wall parts of furnaces, cooling pipe layers are provided with the cooling pipes of the inner layer located in a fireproof construction material (35). These cooling pipes form the reinforcement for the fireproof construction material.The inner layer of cooling pipes face the inside of the vessel and are made in one piece, U-shaped at the upper and the lower and lead into the outer layer of cooling pipes. The outer layer of cooling pipes empty into a liquid distributing conduit provided with at least one integrated bypass openings whereby cooling liquid is at least partially short-circuited between pipes in the outer layer.

Abstract: A locking device for a pivoting window includes a link which is completely embeddable inside the body of the lock mounted on a frame and a strap affixed to the window, the link being set in motion by a combination of sliding and pivoting movements transmitted from the translation motion of an operating knob, parallel to the body of the lock and obtained with pawns attached to the link evolving inside knob-holes of the strap and the body of the lock. This low-crowding device enables locking of the window with constant compression of the watertightness joint of the window.

Abstract: A high tension circuit breaker which includes a stationary switching mechanism, a second switching mechanism axially movable in a first axial direction, a first and second arcing contact operatively connected to the movable switching mechanism and a stationary switching mechanism, respectively, wherein the first contact normally pressingly engages the second contact, a supply for gas under pressure, a nozzle communicating with the gas supply formed in the movable contact and terminating adjacent the first and second contact for communicating expanded gas from the gas supply to the point of pressing engagement of the first and second contact upon cutting out of the gas supply for shifting of the second contact in a second axial direction opposite the first axial direction of movement of the movable switching mechanism upon cutting out of the gas supply.

Abstract: The invention relates to a pump applicable to containers holding a substance to be delivered or dispensed under pressure, which pump is manually operable. The pump includes a hollow stem movable within a hollow body, urged out of the latter by a spring and retained therein by a ring sealingly connectable or hookable on a ring nut which can be secured on the mouth or inlet member of a substance container. A seal of H-cross-section is mounted and movable on the stem and by its lips seals on the inner surface of the hollow body, on the outer surface of the stem, on a tubular extension projecting from the above mentioned ring, and respectively in either of two annular grooves presented by the stem or bodies associated therewith. On moving between such grooves during the movement of the stem, the seal closes or clears a channel through which the pressure substance can exit as previously sucked within the hollow body, which bears on the outward facing surface of an annular edge projecting from the ring nut.

Abstract: A process for producing a 2-cephem or 3-cephem derivative compound of the formula: ##STR1## wherein R.sub.1 represents a substituted or unsubstituted amino radical and R.sub.4 represents hydrogen or a radical selected from the group consisting of carboxy, protected carboxy, ester, acid amide, acid anhydride, acid halide, acid azide and carboxy salt, and the dotted line indicates the alternate bond structure providing 3-cephem or 2-cephem, which comprises:reacting a halogenated derivative selected from the group consisting of a halogenated penam derivative having the formula: ##STR2## a halogenated cephem derivative of the formula: ##STR3## wherein X represents a halogen atom, R.sub.3 represents a radical selected from the group consisting of carboxy, protected carboxy, ester, acid amide, acid anhydride, acid halide, acid azide and carboxy salt, and R.sub.1 is as defined above, or mixtures thereof with a dehydrohalogenoic acid reagent.

Abstract: The invention provides a process for the selective dissolution of oxygenated compounds containing at least one non-ferrous metal selected from the group consisting of nickel, zinc, and copper, present in a mixture of oxygenated compounds containing said at least one non-ferrous metal and at least one element selected from the group consisting of lead, cobalt, iron, manganese, and silicon, and comprises suspending the mixture of the oxygenated metallic compounds in an aqueous phase which, preferably, contains chloride and alkaline earth metal ions; treating the resulting aqueous suspension, maintained at a pH exceeding about 1, with chlorine, preferably at a temperature ranging from about 60.degree. C. to the boiling point of the suspension, to selectively solubilize the said at least one non-ferrous metal while the said at least one element remains in an essentially insoluble residue; and separating the aqueous solution containing the dissolved said at least one non-ferrous metal from the insoluble residue.

Abstract: An effluent gas monitoring apparatus for detecting radioactivities in water, carbon dioxide, and rare gases recovered by introducing the radioactive effluent gas to a water recovery section, a carbon dioxide recovery section and, if necessary, a rare gas concentration section which are arranged parallel to each other. The capacities, scales and gas flow rates of the respective sections which are arranged parallel to each other may be freely selected.