Abstract: A system and method for detecting a functional signal in retinal images. An optical imaging device comprises a stimulation light source, an interrogating light source, and a detector. The retina is stimulated by the stimulation light source. The retina is then illuminated by an interrogation light, and the reflected intensity from the retina is measured at an interrogating spectral band that indicates the state of hemoglobin saturation before and after visual stimulation. The optical changes that result from retinal neuronal activity are captured by the detector. The signal representing the state of hemoglobin saturation before and after visual stimulation is isolated. In an embodiment of the present invention, this signal is isolated using principle components analysis (PCA).

Abstract: An apparatus and method for distributed control of an electrical appliance having a plug and a load and two power carrying conductors connecting the plug to the load, comprising locating power control elements completely within the plug, connecting interface elements to the two power carrying conductors, which interface elements are not within the plug, and transmitting status information from the interface elements to the power control elements by imposition of electrical signals onto the two power carrying conductors, wherein the electrical signals comprise an adjustable duration deadzone at a zero crossing of a sinusoidal excitation.

Abstract: A mechanical dial combination lock for use in safes, file cabinets, security doors, vaults and warehouse doors. The disk type mechanical combination lock features a plurality of annular code discs, a base disc, a latch, an unlatching mechanism, a positioning mechanism, a dialing mechanism, a repositioning mechanism, a code-detecting mechanism, a casing and a dial. The dial combination lock is easily operated by persons familiar with conventional dial-face type combination locks, and yet is may be operated faster, and permits the combination code to be easily changed to any of a greater number of possible code combinations.

Abstract: A medical device with a hydrophilic and lubricious coating, wherein the coating includes a hydrophilic polymeric unit layer deposited on the medical device and cross-linked with a plasma deposited double bond monomer. The hydrophilic polymeric unit can include ethylene oxide with one or more primary or secondary alcohol groups or glycosaminoglycans such as hyaluronic acid, and the double bond monomer includes monomers containing at least one double bond, preferably a C?C, C?N or C?O bond, including N-trimethylsilyl-allylamine, ethylene, propylene and allyl alcohol.

Abstract: Controlled avalanche driver circuits and apparatuses for gas lasers. One embodiment typically delivers short, rapid, high voltage ionizing pulses in combination with an electric field whose magnitude is too low to sustain a normal glow discharge. The plasma is typically impedance matched with the pulse-forming network. Pre-ionization pulses may be generated. The circuits enable very high power, stable lasers.

Abstract: A molecular marker-based method for monitoring and detecting cancer in humans. Aberrant methylation of gene promoters is a marker for cancer risk in humans. A two-stage, or “nested” polymerase chain reaction method is disclosed for detecting methylated DNA sequences at sufficiently high levels of sensitivity to permit cancer screening in biological fluid samples, such as sputum, obtained non-invasively. The method is for detecting the aberrant methylation of the p16 gene, O 6-methylguanine-DNA methyltransferase gene, Death-associated protein kinase gene, RAS-associated family 1 gene, or other gene promoters. The method offers a potentially powerful approach to population-based screening for the detection of lung and other cancers.

Abstract: An antenna beam steering apparatus and method comprising providing an antenna, employing a beam-deflecting lens through which energy passing from and to the antenna is deflected, and rotating the antenna with a single-axis rotator.

Abstract: An electronic device incorporating a tubular shaped carbon molecule supported by a substrate, which molecule is provided with source and drain electrodes, as well as a gate electrode, wherein the gate electrode is a metallic electrode. The metallic electrode has a surface layer of oxide, preferably native oxide. The metallic electrode is preferably aluminium, zinc and copper.

Abstract: An apparatus for transferring effluent from photograph development systems, especially highly automated, high-volume developer systems. A silver-recovery system discharges an iron-rich solution into a tank. Developer fluid and fixer solution is mixed with the iron-rich solution in the tank to buffer its pH. A float in the tank activates a switch located outside the tank to actuate a pump for evacuating the mixed effluent from the tank for disposal. Water may be mixed under pressure with the pumped effluent to reduce clogging in effluent drainage lines due to precipitate and other and build-ups from effluent.

Abstract: A three mirror anastigmatic optic (and corresponding method of making) comprising a primary mirror, a secondary mirror, a tertiary mirror, and a vertex common to the primary and tertiary mirrors.

Abstract: An apparatus and methods for the prevention or minimization of lower extremity venous thrombosis comprising an impedance component disposed at the proximal end of the lower extremity and a compression component disposed at the distal end of the lower extremity. The proximal impedance component is activated to impede return venous blood flow, preferably on the femoral vein, until blood volume in the lower extremity is maximized. In response to deactivation of the proximal compression component, the distal compression component is activated to assist return venous blood flow. The apparatus and methods enhance blood circulation in the lower extremity by increasing washout of stagnant blood from the lower extremity, particularly from the venous sinuses and valve cusps where thrombosis tends to form.

Abstract: A monitoring device and method comprising providing a projectile comprising a sticky medium, one or more sensors embedded therein, and a data transmitter receiving input from said one or more sensors, and firing the projectile at a target to which the medium will attach.

Abstract: An oven for providing radiant and impingement heat to a food item. The oven includes a fan mechanism for drawing air around the radiant heat elements of the oven. The air is then delivered to an impingement tray located adjacent the food item. The air is forced through a series of apertures and onto the food item. At the same time the oven is also being heated by the radiant heat elements. This allows greater heat to be applied to specific locations on the food item. An external heat source is not required to heat the air as the air is heated by the existing radiant heat elements.

Abstract: A mailbox which has a plate along which mail slides before it falls into a rear compartment, which is not easily accessible from the front of the mailbox. A rear door can optionally be locked in its closed position, and only by successfully opening this door can a person obtain mail deposited within the mailbox of the present invention. All of this is achieved while maintaining a relatively small mailbox size.

Abstract: Methods and devices for electrochemical detection of a specific binding pair member utilizing a microsphere with an incorporated electroactive marker, wherein a member of the specific binding pair to be detected is bound, directly or through one or more intermediates, to the microsphere. Multiple specific binding pair members may be detected by use of electrochemically distinguishable electroactive markers. Microspheres with incorporated electroactive markers may include one or more functional groups for binding members of specific binding pairs, and are preferably insoluble in aqueous solvents but soluble in selected organic solvents.

Abstract: Rather than cooling the brain by the relatively slow heat conduction through the low heat conductivity of the bony skull and hair covering the head, the present invention teaches the use of a light weight, easily applied neck encircling collar in firm contact with the soft tissue of the neck, and particularly in good thermal contact with the carotid arteries traversing the neck. A coolant flowing through channels embedded in the collar rapidly cools the blood flowing through the carotid arteries which branch into blood vessels throughout the brain providing vascular access and attendant rapid internal cooling throughout the brain including its deepest recesses. Placing the collar on the patient's neck is easily and quickly accomplished simultaneously with other emergency medical techniques, such as CPR, which maintain the patient's heart and lung activity. The collar of the invention contains no metallic parts; the collar, including the coolant channel, may be non-metallized fabric or plastic.