Abstract: The present invention concerns a method to detect the presence of an enzyme in in vivo or in vitro tissue or cell, which method comprises: (a) obtaining a tissue or cell sample to be analyzed; (b) contacting the tissue or cell sample with a substrate of the structure selected from the group consisting of: X=H or one or more natural or synthetic amino acids with or without amino blocking groups, Y=H or one or more natural or synthetic amino acids with or without amino blocking groups, wherein X and Y are the same or different and are amino acid sequences of between about 1 to 1,000,000 amino acids wherein each amino acid is the same or a different amino acid, with the proviso that at least one of X or Y is at least one amino acid; (c) when an enzyme is present in the tissue or cell sample which degrades X, Y and combinations thereof, fluorescent cresyl violet is released in the tissue sample producing a color change; (d) detecting the presence and amount of the enzyme pres

Abstract: A four corner bag constructed of flexible thermoplastic sheet or film material having overlying front and rear wall panels and a bottom sealed end. The upper portion of the bag includes a first closure region terminating in a top sealed end, a second closure region disposed inwardly of the top sealed end, and a perforated seal or tear strip extending across the width of the bag and located between the first and second closure regions. The second closure region includes an inner heat seal which extends approximately halfway across the width of the bag and a reclosable fastener which extends the remaining distance across the bag. In one embodiment, the inner heat seal is oriented transversely across the bag while the reclosable fastener is upwardly angled so that it forms a natural pour spout during use. In other embodiments, the reclosable fastener is transversely oriented while the inner heat seal is angled.

Abstract: A water soluble derivative of buckministerfullerene (C60) having antiviral and virucidal properties is used to inhibit human retroviral replication and infections. The derivatized fullerene is symmetrically substituted with polar organic moieties containing 1 to 20 carbon atoms and optionally further containing oxygen or nitrogen.

Abstract: Fabrication techniques for an integrated sputtering target assembly include pressure assisted bonding of soldered layers of material, in particular, soldering of the target material to its backing plate; pressure assisted curing of structural adhesives used to join a finned cover plate to a backing plate which between them form passages for fluid cooling; and bonding an electrical insulating layer to the back surface of the backing plate. The pressure to assist in bonding is typically applied by an autoclave. The cooling fluid passages disposed between a cover and a finned backing plate can be sealed by using laser welding or electron beam welding rather than closing the cooling passages with structural adhesives.

Abstract: In a substrate vacuum processing chamber, a second inner slit passage door apparatus and method to supplement the normal slit valve and its door at the outside of the chamber. The inner slit passage door, blocks the slit passage at or adjacent the substrate processing location in a vacuum processing chamber to prevent process byproducts from depositing on the inner surfaces of the slit passage beyond the slit passage door and improves the uniformity of plasma in the processing chamber by eliminating a large cavity adjacent to the substrate processing location into which the plasma would otherwise expand.

Abstract: A structure and method are present where a sidewall of a load lock chamber is formed by extrusion, to produce a reproducible tubular structure to form the walls of a vacuum chamber with greatly improved vacuum performance. The use of an extruded structure reduces the dimensional variability, increases the uniformity of a surface finish, and provides uniform top and bottom sealing arrangements, which allow full and easy access to the inside of the sidewalls for cleaning. In another arrangement heat transfer fluid passages can be formed in the wall of the chamber simultaneously as the wall of the chamber is extruded. Heating of cooling liquid can then be circulated through the passages in the wall of the chamber to heat the walls of the chamber as sometimes required to prevent condensation on the inside of the chamber walls, or provide cooling as is required for cool down of a wafer, after processing at an elevated temperature.

Abstract: The method comprises forming a dry preunit including a stack of cells. Each cell is formed by placing sequentially a conductive support sheet coated on one or both sides with a porous conductive material except at the perimeter edge surfaces, an ion permeable or semi-permeable space separator, a gasket, at least one hollow capillary tube having a melting point higher than the gasket material. Upon heating the gasket material flows, adheres to, and seals the edges of the stack creating a solid integral stack of layers of alternating electrically conductive sheet coated with a porous electrically conducting material and a separator. The gasket material creates a continuous integral external polymer enclosure having hollow capillary tubes. After an electrolyte is introduced into the preunit, the capillary tubes are sealed.

Abstract: A valve lockout device having two pieces. A first piece of the device is a hollow object, substantially tubular or block-shaped, open at a bottom end and having slots open on two sides, that fits over a valve whose handle is to be fixed (or locked). A pocket in the first piece receives the handle and limits the motion of the handle relative to the valve body, thereby preventing operation of the valve. A second piece of the device is a substantially U-shaped object which is pivotally attached to the first piece. When the second piece is rotated to a closed position, it captures the valve handle in the pocket of the first piece, thereby preventing the valve lockout device from being removed. When the second piece is in the closed position, a padlock loop on the first piece extends through a padlock receiving opening in the second piece. Putting a padlock through the padlock loop will prevent the second piece from being rotated out of its closed position, thereby locking the device to the valve.

Abstract: A compact lifting device whose load arm is fixed to a cover of lid of a processing chamber provides, a tubular pan body with an externally easily adjustable spring counterweight type member passing through the tubular center of the pan body. The spring member is cleverly mounted between an upper and lower portion of the pan body and rotates with the pan body as the lift mechanism swings from side to side. An innovative center core mounting of the spring device allows loads from the lifted weight to be equally distributed on two side of the pan body. The rotation of the pan body is by the use of bearings which are constructed so that a flange of pan body is utilized as two races of a ball bearing further reducing the space need for mounting such a lifting device.

Abstract: An improved lift mechanism includes a configuration having two sections of bellows welded to a central flange. The central flange provides support for a precisely aligned lift pin support structure. The efficient utilization of space provides space for an enlarged stem while minimizing the interaction between pieces within the processing chamber. Outside the vacuum limits of the processing chamber, a catch arrangement is provided as part of a linkage that allows a single vertical drive to be utilized to manipulate both the vertical motion of lift pins and vertical motion of the pedestal supporting a substrate in a processing chamber. In one configuration a unitized lift mechanism can be replaced as a unit. Particular orientations for utilizing a lift pin support plate with ceramic inserts is disclosed to reduce particle generation within the processing chamber.

Abstract: The case of maintainability and component replacement for a vacuum processing chamber is enhanced by providing a vacuum chamber roof assembly whose connection to the vacuum chamber body is through a clamped connection. Accessories needed for the roof assembly, e.g. cooling, heating, RF power, are separately supported and terminated to an accessories supporting cold plate, which is separately mounted such it is easily movable, for example by hinging from the chamber body. The roof of the chamber can then easily be separated from the chamber body and replaced. In an further mode the chamber roof can be easily raised to provide easy access to modular components inside the processing chamber. All components exposed to the plasma in the chamber can be easily accessed and replaced.

Abstract: The present invention relates to a process to aminate electrophilic aromatic compounds by vicarious nucleophilic substitution of hydrogen using quaternary hydrazinium salts. The use of trialkylhydrazinium halide, e.g., trimethylhydrazinium iodide, as well as hydroxylamine, alkoxylamines, and 4-amino-1,2,4-triazole to produce aminated aromatic structures, such as 1,3-diamino-2,4,6-trinitrobenzene (DATB), 1,3,5-triamino-2,4,6-trinitrobenzene (TATB) and 3,5-diamino-2,4,6-trinitrotoluene (DATNT), is described. DATB and TATB are useful insensitive high explosives. TATB is also used for the preparation of benzenehexamine, a starting material for the synthesis of novel materials (optical imaging devices, liquid crystals, ferromagnetic compounds).

Abstract: A prepolymer composition for producing polyurethane insulating foams from pressure tanks which consists of a prepolymer component with at least one PU prepolymer with a content of NCO groups of 4 to 20 wt % and usual additives, as well as a propellant component, with a content of 0.01 to 2 wt %, based on the prepolymer component, of polybutadiene.

Abstract: The present invention relates to an improved method to produce an electrical storage device having useful characteristics such as higher charge density, small volume, long-term reliable charge/discharge cycles, low leakage current, and the like. The dry preunit has useful properties in that it can be stored for long periods prior to contact with a non-aqueous or aqueous electrolyte. When the electrode surfaces are contacted with a non-aqueous or aqueous electrolyte, the novel capacitors produced are useful as a portable power supply in applications such as in defibrillator, electrical vehicles, radiotelephones etc.

Abstract: The present invention concerns a process to produce a high surface area niobium oxynitride, tantalum oxynitride, vanadium oxynitride, zirconium oxynitride, titanium oxynitride or molybdenum oxynitride coated substrate for use as an electrical energy storage component in a capacitor or a battery configuration.

Abstract: A particular configuration of a compact self-aligning lift mechanism is provided for lifting the stem of a pedestal in a processing chamber while minimizing process anomalies due to geometric misalignment and binding of moving pieces. The force associated with supporting a stem in a processing chamber is routed through a first arm through a base portion of a carrier bracket where it engages a linear bearing such that the truck and track of the linear bearing absorb all forces riot aligned with the bearing. A second arm extending from the base portion, for example through a set of slots adjacent to the bearing track support member, is attached to a lift mechanism which can oppose the force from the pedestal stem such that the displacements of the first and second arms are predictable based on the force on that arm.

Abstract: The invention discloses fluorescent chelator compounds that are especially useful to monitor and measure cytosolic concentrations of alkali metal cations such as Na.sup.+, K.sup.+, and Li.sup.+. The new compounds are comprised of: (1) crown ethers (that may or may not have substituent groups attached to the core carbons, but will always contain at least one core nitrogen) that are linked via the core nitrogen(s) to at least one (2) fluorophore that contains an additional heteroaromatic liganding center. In the currently preferred dye, SBFI, the core compound is crown ether 1,7-diaza-4,10,13-trioxacyclopentadecane and the heteroaromatic fluorophores are benzofurans that are linked to isophthalate groups. Selectivities for Na.sup.+ over K.sup.+ of about 20 are observed, resulting in effective dissociation constants for Na.sup.+ of about 20 mM against a background of 120 mM K.sup.+. Increasing ?Na.sup.