Patents Represented by Attorney Philip B. Polster

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  • Pyrrolo[2,1-c][1,2,4] thiadiazoles and Pyrollo[2,1-c][1,12,4]oxadiazoles useful as nitric oxide synthase inhibitors
    Patent number: 6552052
    Abstract: Pyrrolo[2,1-c][1,2,4]thiadiazole or pyrollo[2,1-c][1,2,4]oxadiazoles having the formula: or pharmaceutically acceptable salts thereof, useful as nitric oxide synthase inhibitors wherein each substituent is defined herein.
    Type: Grant
    Filed: March 26, 2001
    Date of Patent: April 22, 2003
    Assignee: Monsanto/G.D. Searle
    Inventors: Donald W. Hansen, Jr., R. Keith Webber, E. Ann Hallinan, Mihaly V. Toth, Barnett S. Pitzele, Alok K. Awasthi, Alan E. Moormann, Suzanne Metz, Jeffery S. Snyder, William M. Moore, Jeffrey A. Scholten
  • 2-amino-5, 6 heptenoic acid derivatives useful as nitric oxide synthase inhibitors
    Patent number: 6545170
    Abstract: The present invention contains novel compounds useful as nitric oxide synthase inhibitors.
    Type: Grant
    Filed: April 13, 2001
    Date of Patent: April 8, 2003
    Assignee: Pharmacia Corporation
    Inventors: Barnett S. Pitzele, James A. Sikorski, Donald W. Hansen, Jr., Ronald Keith Webber, Mihaly V. Toth, Jeffrey A. Scholten, Jeffrey S. Snyder
  • Homoiminopiperidinyl hexanoic acid inhibitors of inducible nitric oxide synthase
    Patent number: 6495544
    Abstract: Homoiminopiperidinyl Hexanoic Acid derivatives and pharmaceutically acceptable salts thereof useful in the inhibition of the inducible isoform of nitric oxide synthase are disclosed.
    Type: Grant
    Filed: August 1, 2001
    Date of Patent: December 17, 2002
    Assignee: Pharmacia Corporation
    Inventors: Donald W. Hansen, Jr., Jeffrey S. Snyder, Alan E. Moormann, Alok K. Awasthi, Ronald Keith Webber, Thaddeus S. Franczyk, Mahima Trivedi
  • Heterobicyclic and tricyclic nitric oxide synthase inhibitors
    Patent number: 6489323
    Abstract: The current invention relates to compounds of Formula I pharmaceutical compositions and methods of use as nitric oxide synthase inhibitors, wherein the substituents are defined in the application.
    Type: Grant
    Filed: June 10, 1999
    Date of Patent: December 3, 2002
    Assignee: G.D. Searle & Co.
    Inventors: Donald W. Hansen, Jr., R. Keith Webber, E. Ann Hallinan, Mihaly V. Toth, Barnett S. Pitzele, Alok K. Awasthi, Alan E. Moormann, Suzanne Metz, Jeffery S. Snyder, William M. Moore, Jeffrey A. Scholten
  • Halogenated 2-amino-4, 5 heptenoic acid derivatives useful as nitric oxide synthase inhibitors
    Patent number: 6465518
    Abstract: The present invention contains halogenated 2-amino-4,5 heptenoic acid derivatives useful as nitric oxide synthase inhibitors.
    Type: Grant
    Filed: April 13, 2001
    Date of Patent: October 15, 2002
    Assignee: Pharmacia Corporation
    Inventors: Donald W. Hansen, Jr., Ronald Keith Webber, Alok K. Awasthi, Pamela T. Manning
  • Halogenated 2-amino-5,6 heptenoic acid derivatives useful as nitric oxide synthase inhibitors
    Patent number: 6465686
    Abstract: The present invention discloses halogenated 2-amino-5,6 heptenoic acid derivatives useful as nitric oxide synthase inhibitors.
    Type: Grant
    Filed: April 13, 2001
    Date of Patent: October 15, 2002
    Assignee: Pharmacia Corporation
    Inventors: Margaret L. Grapperhaus, James A. Sikorski, Alok K. Awasthi, Lijuan J. Wang, Barnett S. Pitzele, Donald W. Hansen, Jr., Pamela T. Manning
  • Imino pyrrolidine derivatives useful as nitric oxide synthase inhibitors
    Patent number: 6448286
    Abstract: The current invention discloses useful pharmaceutical compositions containing amidino derivative useful as nitric oxide synthase inhibitors.
    Type: Grant
    Filed: July 28, 1998
    Date of Patent: September 10, 2002
    Assignee: G.D. Searle & Co.
    Inventors: Donald W. Hansen, Jr., Mark G. Currie, E. Ann Hallinan, Kam F. Fok, Timothy J. Hagen, Arija A. Bergmanis, Steven W. Kramer, Len F. Lee, Suzanne Metz, William M. Moore, Karen B. Peterson, Barnett S. Pitzele, Dale P. Spangler, R. Keith Webber, Mihaly V. Toth, Mahima Trivedi, Foe S. Tjoeng
  • Aminotetrazole derivatives useful as nitric oxide synthase inhibitors
    Patent number: 6410542
    Abstract: The current invention discloses aminotetrazole derivatives useful as nitric oxide synthase inhibitors.
    Type: Grant
    Filed: October 13, 2000
    Date of Patent: June 25, 2002
    Assignee: G. D. Searle & Co.
    Inventors: E. Ann Hallinan, Donald W. Hansen, Jr., Sofya Tsymbalov
  • Amidino compound and salts thereof useful as nitric oxide synthase inhibitors
    Patent number: 6403830
    Abstract: The present invention relates to S-[2-[(1-Iminoethyl)amino]ethyl]-2-methyl-L-cysteine, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: March 23, 2001
    Date of Patent: June 11, 2002
    Assignee: Pharmacia Corporation
    Inventors: Ronald Keith Webber, Richard C. Durley, Alok K. Awasthi, Arija A. Bergmanis, Scott S. Ganser, Timothy J. Hagen, E. Ann Hallinan, Donald W. Hansen, Jr., Brian S. Hickory, Alan E. Moormann, Barnett S. Pitzele, Michelle A. Promo, Richard R. Schartman, Jeffrey S. Snyder, Mahima Trivedi, Sofya Tsymbalov
  • Imidazoles useful as nitric oxide synthase inhibitors
    Patent number: 6344473
    Abstract: 1,3-diazolino and 1,3-diazolidino heterocycle derivatives useful as nitric oxide synthase inhibitors.
    Type: Grant
    Filed: August 7, 2000
    Date of Patent: February 5, 2002
    Assignee: G.D. Searle & Co.
    Inventors: Donald W. Hansen, Jr., Arija A. Bergmanis, Timothy J. Hagen, E. Ann Hallinan, Steven W. Kramer, Suzanne Metz, Karen B. Peterson, Barnett S. Pitzele, Foe S. Tjoeng, Mihaly V. Toth, Mahima Trivedi, R. Keith Webber, Sofya Tsymbalov, Rolando E. Gapud
  • Halogenated amidino amino acid deviratives useful as nitric oxide synthase inhibitors
    Patent number: 6344483
    Abstract: The current invention discloses halogenated amidino amino acid derivatives useful as nitric oxide synthase inhibitors, and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: January 31, 2000
    Date of Patent: February 5, 2002
    Assignee: G. D. Searle & Co.
    Inventors: E. Ann Hallinan, Barnett S. Pitzele, Dale P. Spangler, Mihaly V. Toth, R. Keith Webber, Arija A. Bergmanis, Timothy J. Hagen, Sofya Tsymbalov
  • Motion transmitting system
    Patent number: 4567790
    Abstract: A motion transmitting device having an input shaft and a concentric output shaft assembly, and an eccentrically rotated gear driven by the input shaft to provide an eccentric output. The gear has teeth which engage and subsequently disengage with independently movable meshing elements, such as pins. A pair of datum members have round holes to individually guide and limit movement of the meshing elements within predetermined limits of orbital motion relative to the datum members. The eccentric output drive of the gear is converted to rotary motion of the output shaft assembly. The input shaft and the output shaft assembly are rotatable about a common axis.
    Type: Grant
    Filed: July 16, 1984
    Date of Patent: February 4, 1986
    Assignee: Emerson Electric Company
    Inventors: Roger P. Butterfield, Charles M. Allaben, Jr.
  • Toy transceiver package
    Patent number: D249490
    Type: Grant
    Filed: October 18, 1976
    Date of Patent: September 19, 1978
    Assignee: Steven Manufacturing Company
    Inventors: Beverly W. Taylor, Reet Thomas, Jr.
  • Bottle container
    Patent number: D251352
    Type: Grant
    Filed: October 6, 1976
    Date of Patent: March 20, 1979
    Inventor: Joseph M. Menius
  • Glow plug energizer
    Patent number: D251780
    Type: Grant
    Filed: March 4, 1977
    Date of Patent: May 8, 1979
    Assignee: Emerson Electric Co.
    Inventor: Benjamin Bowsky
  • Knife
    Patent number: D256217
    Type: Grant
    Filed: October 5, 1977
    Date of Patent: August 5, 1980
    Assignee: K-S-H, Inc.
    Inventor: William W. Korn
  • Toy coffee maker
    Patent number: D257732
    Type: Grant
    Filed: April 17, 1978
    Date of Patent: December 30, 1980
    Assignee: Steven Manufacturing Company
    Inventor: Ronald R. Klawitter
  • Toy mixer
    Patent number: D257733
    Type: Grant
    Filed: April 17, 1978
    Date of Patent: December 30, 1980
    Assignee: Steven Manufacturing Company
    Inventor: Ronald R. Klawitter
  • Toy circular saw
    Patent number: D258161
    Type: Grant
    Filed: April 17, 1978
    Date of Patent: February 3, 1981
    Assignee: Steven Manufacturing Company
    Inventor: Ronald R. Klawitter
  • Toy chain saw
    Patent number: D258299
    Type: Grant
    Filed: April 17, 1978
    Date of Patent: February 17, 1981
    Assignee: Steven Manufacturing Company
    Inventor: Ronald R. Klawitter