Patents Represented by Attorney, Agent or Law Firm Reed A. Duthler
  • Patent number: 8244355
    Abstract: A system and method are provided for determining an index of autonomic nervous system (ANS) or sympathetic nervous system (SNS) activity for use in patient monitoring or therapy delivery control. An ANS or SNS index is calculated as a function of multiple monitored physiological variables that strongly correlate to changes in autonomic or sympathetic tone. These ANS-influenced variables are derived from selected hemodynamic and/or electrical signals and may include variables relating to any of: the maximum rate of pressure rise (dP/dtmax), the maximum rate of pressure decline (dP/dtmin), pulse pressure (PP), pre-ejection time interval (PEI) and/or systolic time interval (STI), heart rate (HR), heart rate variability (HRV), and baro-reflex gain. Changes in the ANS or SNS index may be used to automatically adjust a device delivered therapy.
    Type: Grant
    Filed: October 29, 2004
    Date of Patent: August 14, 2012
    Assignee: Medtronic, Inc.
    Inventors: Tommy D. Bennett, Edwin G. Duffin, Barbro Kjellstrom
  • Patent number: 8233994
    Abstract: An implantable medical device that includes an elongated body having a proximal end and a distal end, a helical fixation member extending from the distal end of the elongated body, the helical fixation member including a distal tip for affixing the distal end of the elongated body at an implant site, and a tracking member extending from the distal end of the elongated body, through the helical fixation member and outward from the distal tip of the helical fixation member for tracking along an implant pathway during implantation of the implantable medical device.
    Type: Grant
    Filed: April 8, 2009
    Date of Patent: July 31, 2012
    Assignee: Medtronic, Inc.
    Inventors: John L. Sommer, Douglas N. Hess
  • Patent number: 8229572
    Abstract: A lead delivery apparatus includes an electrically conductive lead for an implantable medical device, a delivery shaft for delivering the lead to a target site, a fixator and a pulley structure. A flexible member is coupled to the delivery shaft and the lead and engages the pulley structure such that pulling a first portion of the flexible member moves the lead to the target site.
    Type: Grant
    Filed: July 1, 2009
    Date of Patent: July 24, 2012
    Assignee: Medtronic, Inc.
    Inventors: Ronald A. Drake, Lindsey M. Tobin, Stanten C. Spear, Scott W. Hayden, Andrea J. Asleson, Steven Lawrence Waldhauser, Kendra Yasger, Gary Fiedler
  • Patent number: 8229560
    Abstract: In an implantable medical device that provides atrial and ventricular pacing in an atrial-based pacing mode, longer periods of time are permitted for intrinsic AV conduction to occur. By monitoring the patient's AV delay under these circumstances, useful information is obtained that can be correlated to other patient conditions or symptoms.
    Type: Grant
    Filed: April 1, 2011
    Date of Patent: July 24, 2012
    Assignee: Medtronic, Inc.
    Inventor: Catherine R. Condie
  • Patent number: 8224447
    Abstract: A system, comprising a sterilizable package; an implantable medical device placed inside the sterilizable package; and an electrical interface electrically coupled to the implantable medical device and extending from inside the sterilizable package to outside the sterilizable package. In various embodiments, the interface may include package contacts electrically coupled to electrode terminals on the implantable medical device, patient terminals and conductors extending between the package contacts and the patient terminals.
    Type: Grant
    Filed: November 30, 2005
    Date of Patent: July 17, 2012
    Assignee: Medtronic, Inc.
    Inventors: William K. Wenger, Paul G. Krause, William J. Plombon, Steven N. Lu, Sean B. McAdams, Brian B. Lee, Lee Stylos, Judy B. Salzer, G. Jordan Montgomery
  • Patent number: 8219212
    Abstract: A medical electrical lead includes a canted lead body distal portion extending from an approximately straight lead body proximal portion; the canted distal portion includes an approximately straight segment and a hump-like segment extending from a first end, in proximity to the approximately straight segment, to a second end. The lead further includes a first electrode coupled to the approximately straight segment of the distal portion and a second electrode coupled to the distal portion in proximity to a second end of the hump-like segment.
    Type: Grant
    Filed: August 23, 2004
    Date of Patent: July 10, 2012
    Assignee: Medtronic, Inc.
    Inventors: Ryan T. Bauer, Yong D. Zhao
  • Patent number: 8219213
    Abstract: An implantable medical lead configured for active fixation in the vasculature of a patient includes an elongated lead body having a central lumen and a distal tip. Disposed within the central lumen are a fixation helix and an elongated member, such as a lead coil, coupled to the fixation helix. The elongated member is adapted to rotate the fixation helix, thereby causing it to advance or retract within the central lumen of the lead body. The lead body includes a window along a portion of its length through which the fixation helix may be affixed to a blood vessel of the patient's vasculature.
    Type: Grant
    Filed: December 30, 2005
    Date of Patent: July 10, 2012
    Assignee: Medtronic, Inc.
    Inventors: John L. Sommer, Douglas N. Hess
  • Patent number: 8219200
    Abstract: A system, comprising a sterilizable package; an implantable medical device placed inside the sterilizable package; and an electrical interface electrically coupled to the implantable medical device and extending from inside the sterilizable package to outside the sterilizable package. In various embodiments, the interface may include package contacts electrically coupled to electrode terminals on the implantable medical device, patient terminals and conductors extending between the package contacts and the patient terminals.
    Type: Grant
    Filed: June 29, 2010
    Date of Patent: July 10, 2012
    Assignee: Medtronic, Inc.
    Inventors: William K. Wenger, Paul G. Krause, William J. Plombon, Steven N. Lu, Sean B. McAdams, Brian B. Lee, Lee Stylos, Judy B. Salzer, G. Jordan Montgomery
  • Patent number: 8211028
    Abstract: A system and method of determining hemodynamic parameters uses sensed ventricular blood pressure during a portion of ventricular pressure waveform following peak pressure. An estimated arterial diastolic pressure is based upon an amplitude of the sensed ventricular pressure corresponding to a time at which a first derivative of ventricular pressure as a function of time is at a minimum (dP/dtmin). Fill parameters such as isovolumetric relaxation constant, ventricular suction pressure, atrial kick pressure, and transvalve pressure gradient are derived from measured pressures representing minimum ventricular pressure, ventricular diastolic pressure, and diastasis pressure.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: July 3, 2012
    Assignee: Medtronic, Inc.
    Inventors: Mustafa Karamanoglu, Tommy D. Bennett
  • Patent number: 8214041
    Abstract: This document provides a simple and automatic method for determining an optimal AV interval and/or range of AV intervals for, in an exemplary embodiment, LV-only pacing. Such a method provides significant advantages for patients while reducing burdens related to post-implant follow-up by clinicians in that it greatly reduces the need for doing echocardiographic-based AV interval optimization procedures as well as providing a way to dynamically optimize AV intervals as the patient moves about their activities of daily living (ADL).
    Type: Grant
    Filed: April 19, 2005
    Date of Patent: July 3, 2012
    Assignee: Medtronic, Inc.
    Inventors: Berry M. Van Gelder, M. S. J. Pilmeyer, John E Burnes
  • Patent number: 8214045
    Abstract: A lead implant system includes a lead coupling device, which is configured to couple a lead during an implant procedure, in communication with a medical device and an implantable medical device, which is contained within a package that includes an electrical interface for electrical coupling with an electrical contact of the implantable medical device. The electrical interface facilitates coupling of the packaged medical device to an electrical contact of another medical device, which is located outside the package. If the electrical contact of the packaged device is mounted within a bore of the device, then the connector structure allows for passage of a sterilizing gas into the connector bore, and past the connector contact, within the bore.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: July 3, 2012
    Assignee: Medtronic, Inc.
    Inventors: Christine G. Kronich, John L. Sommer, William K. Wenger, Michael D. Eggen, Gerald Jordan Montgomery, Joseph A. DuPay
  • Patent number: 8200333
    Abstract: An implantable medical device provides ventricular pacing capabilities and optimizes AV intervals for multiple purposes. In general, intrinsic conduction is promoted by determining when electromechanical systole (EMS) ends and setting an AV interval accordingly. EMS is determined utilizing various data including QT interval, sensor input, and algorithmic calculations.
    Type: Grant
    Filed: March 2, 2010
    Date of Patent: June 12, 2012
    Assignee: Medtronic, Inc.
    Inventors: Raul Chirife, William J. Combs, Russell L. Lundstrom
  • Patent number: 8195280
    Abstract: A method of classifying arrhythmias using scatter plot analysis to define a measure of variability of a cardiac rhythm parameter such as for example, without limitation, R-R interval, A-A interval, and the slope of a portion of a cardiac signal, is disclosed. The variability measurement is derived from a scatter plot of a cardiac rhythm parameter, employing a region counting technique that quantifies the variability of the cardiac rhythm parameter while minimizing the computational complexity. The method may be employed by an implantable medical device or system, such as an implantable pacemaker or cardioverter defibrillator, or by an external device or system, such as a programmer or computer. The variability measurement may be correlated with other device or system information to differentiate between atrial flutter and atrial fibrillation, for example. The variability information may also be used by the device or system to select an appropriate therapy for a patient.
    Type: Grant
    Filed: December 31, 2009
    Date of Patent: June 5, 2012
    Assignee: Medtronic, Inc.
    Inventors: Peter M. Van Dam, Joanneke G. Groen
  • Patent number: 8187198
    Abstract: An improved system for measuring changes in blood flow, particularly in the context of an automatic arrhythmia treatment device. The system includes a heater, exposable to a bloodstream, a driver providing power to the heater, a temperature sensor, isolated from the blood stream and thermally coupled to the temperature of the heater and a measurement circuit coupled to the temperature sensor, providing signals indicative of blood flow. The system may include an intravascular lead having a lead body wherein the heater is mounted to the lead body so as to dissipate its generated heat into the blood. The heater and temperature sensor may be thermally insulated from the lead body and the heater and the temperature sensor may be on substantially a single isotherm during operation.
    Type: Grant
    Filed: April 9, 2009
    Date of Patent: May 29, 2012
    Assignee: Medtronic, Inc.
    Inventor: Sourav Bhunia
  • Patent number: 8175695
    Abstract: A method and system for detecting T-wave alternans for use in an implanted medical device uses wave transformation of QT intervals to obtain a reliable measure of TWA. In one embodiment, an array provides alternating sign multiplication factors which are applied respectively to n consecutive QT values. Each successive QT value is high pass filtered and moved sequentially through a queue so that each cycle each of the n QT values is multiplied by one of the factors; the products are summed and made absolute to provide an alternans match value. The alternans match is compared with a noise threshold signal, and alternans is declared when the match exceeds the threshold by a predetermined amount. The array is programmable and can be varied, providing a high degree of flexibility to optimize the test for the patient.
    Type: Grant
    Filed: February 18, 2010
    Date of Patent: May 8, 2012
    Assignee: Medtronic, Inc.
    Inventors: Mattias Rouw, Christianus J. J. E. Van Groeningen, Henricus Willem M. De Bruyn
  • Patent number: 8155758
    Abstract: This disclosure relates to fault tolerant instantiations of a cardiac therapy delivery device such as an implantable cardiac stimulator (e.g., an implantable pulse generator, IPG, and/or an implantable cardioverter-defibrillator, ICD) coupled to an implantable physiologic sensor (IPS). According to the disclosure delivery of cardiac pacing and/or cardioversion-defibrillator therapy delivery can cause errors in output signals from an IPS. Resolution of such errors involves selectively energizing (or disconnecting the output signal from) the IPS during pacing and/or defibrillation therapy delivery. Programmable signal “blanking” in lieu of or in addition to the foregoing also improves the integrity of the output signal (i.e., continuously energize the IPS and ignore parts of the output signal). An ICD having a transient weakness in an insulated conductor used for the IPS signal can likewise have the IPS de-energized and/or blank the IPS output signal during high voltage therapy delivery.
    Type: Grant
    Filed: April 27, 2006
    Date of Patent: April 10, 2012
    Assignee: Medtronic, Inc.
    Inventors: Glenn M. Roline, Michael B. Terry, Jonathan P. Roberts, James D. Reinke, Robert A. Corey
  • Patent number: 8152730
    Abstract: A medical device and method for determining baroreflex sensitivity (BRS) based on one or more respiration cycles. The BRS determination may be performed continuously based on measurements of heart rate, blood pressure, and respiration cycles.
    Type: Grant
    Filed: January 25, 2011
    Date of Patent: April 10, 2012
    Assignee: Medtronic, Inc.
    Inventors: Yong K. Cho, Tommy D. Bennett
  • Patent number: 8147275
    Abstract: An interface adapter for an implantable medical electrical lead facilitates temporary electrical connection between an external medical device and a connector terminal of the lead. A sidewall of the adapter surrounds a receptacle of the adapter and includes a contact opening formed therethrough, to the receptacle; the sidewall further includes at least one external feature that holds a connector member of the external medical device in a tilted orientation. The tilted orientation biases a contact surface of the connector member through the contact opening and into electrical contact with an exposed connector contact of the lead connector terminal, when the terminal is inserted within the receptacle of the adapter.
    Type: Grant
    Filed: January 27, 2011
    Date of Patent: April 3, 2012
    Assignee: Medtronic, Inc.
    Inventors: Ronald A. Drake, Stanten C. Spear, Lester O. Stener
  • Patent number: 8150513
    Abstract: A system and method for monitoring left ventricular (LV) lateral wall motion and for optimizing cardiac pacing intervals based on left ventricular lateral wall motion is provided. The system includes an implantable or external cardiac stimulation device in association with a set of leads including a left ventricular epicardial or coronary sinus lead equipped with a motion sensor electromechanically coupled to the lateral wall of the left ventricle. The device receives and processes wall motion sensor signals to determine a signal characteristic indicative of systolic LV lateral wall motion or acceleration. An automatic pacing interval optimization method evaluates the LV lateral wall motion during varying pacing interval settings, including atrial-ventricular intervals and inter-ventricular intervals and selects the pacing interval setting(s) that correspond to LV lateral wall motion associated with improved cardiac synchrony and hemodynamic performance.
    Type: Grant
    Filed: October 27, 2009
    Date of Patent: April 3, 2012
    Assignee: Medtronic, Inc.
    Inventor: Edward Chinchoy
  • Patent number: 8145308
    Abstract: A medical device and method for determining a parameter for delivery of a predetermined pacing therapy that includes a plurality of electrodes to deliver a pacing therapy, including the predetermined pacing therapy, and a control unit to control the timing of the delivery of the pacing therapy, including the predetermined pacing therapy, by the electrodes. A processor generates a first template in response to the pacing therapy being delivered to only one of a right ventricle and a left ventricle, and a second template in response to the pacing therapy being delivered to only the other of the right ventricle and the left ventricle, and determines the parameter in response to a comparing of subsequently delivered pacing therapy to the first template and the second template.
    Type: Grant
    Filed: March 13, 2008
    Date of Patent: March 27, 2012
    Assignee: Medtronic, Inc.
    Inventors: Aleksandre T Sambelashvili, Thomas J Mullen, Jeffrey M. Gillberg