Patents Represented by Attorney, Agent or Law Firm Robert A. Franks
  • Patent number: 8338617
    Abstract: A process for preparing (4S,5R)-5-carboxymethyl-2,2-dimethyl-4-phenyl-oxazolidine-3-carboxylic acid t-butyl ester, an intermediate in the preparation of anticancer compounds having a taxane skeleton, such as paclitaxel, docetaxol, etc.
    Type: Grant
    Filed: November 18, 2005
    Date of Patent: December 25, 2012
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: Siripragada Mahender Rao, Ramanatham Josyula, C. Naveen Kumar Reddy, Veerababu Kagita, Yusuf Vohra
  • Patent number: 8058438
    Abstract: Eszopiclone is prepared by reacting zopiclone with an enatiomerically pure di-p-toluoyl tartaric acid, recovering a solid salt, and reacting a solid salt with a base. Zopiclone is prepared by reacting 6-(5-chloropyrid-2-yl)-5-hydroxy-7-oxo-5,6-dihydropyrrolo[3,4-b]-pyrazine with 1-chlorocarbonyl-4-methylpiperazine hydrochloride.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: November 15, 2011
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.,
    Inventors: Venkata Naga Brahmeswara Rao Mandava, Sreenadhacharyulu Kandala, Mukunda Reddy Jambula, Raveendra Reddy Chinta
  • Patent number: 8053000
    Abstract: Substantially non-porous polymeric microparticles comprising a hydrophobic polymer and a plasticizer, and containing therein a bioactive or bioinactive agent.
    Type: Grant
    Filed: June 5, 2006
    Date of Patent: November 8, 2011
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.,
    Inventors: Arutla Srinivas, Harshal P. Bhagwatwar, Vakati Venkat Arvind, Saravana Perumal, Vemula Sathya Narayana, Mandavalli Srirama Sarveswara Rao, Venkateswarlu Vobalaboina, Nookaraju Venkata Sreedharala
  • Patent number: 8039619
    Abstract: Voriconazole is prepared by a process comprising condensing 1-(2,4-difluorophenyl)-2-(1H-1,2,4-triazole-1-yl)ethanone with 4-chloro-6-ethyl-5-fluoropyrimidine, in a ketone, ether, aliphatic hydrocarbon, or aromatic hydrocarbon solvent, to give (2R,3S/2S,3R)-3-(4-chloro-5-fluoropyrimidin-6-yl)-2-(2,4-diflurophenyl)-1-(1H -1,2,4-triazole-1-yl)butan-2-ol.
    Type: Grant
    Filed: June 10, 2010
    Date of Patent: October 18, 2011
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: Venkataraman Sundaram, Venkata Bhaskara Rao Uppala, Surya Prabhakar Akundi, Venkateswarlu Muvva, Vijayawardhan Chitta, Alekhya Donthula, Manoj Ramesh Kharkar, Surya Narayana Devarakonda, Subba Reddy Peddireddy
  • Patent number: 8003820
    Abstract: A process for preparing a bisphosphonate compound comprises reacting a carboxylic acid with a phosphonating agent, in a cresol solvent.
    Type: Grant
    Filed: October 18, 2006
    Date of Patent: August 23, 2011
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: Venkata Naga Brahmeswara Rao Mandava, Radha Krishna Singam Setty, Nagaraju Manne
  • Patent number: 7977478
    Abstract: Crystalline polymorphic forms of vardenafil and vardenafil hydrochloride, and processes for preparing them.
    Type: Grant
    Filed: September 27, 2006
    Date of Patent: July 12, 2011
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: Eswaraiah Sajja, Ravindar Reddy Koppera, Satyanarayana Revu, Venkata Reddy Vajrala, Vijayapal Reddy Kanumathi
  • Patent number: 7943781
    Abstract: A process comprising cyclizing 3-amino-4-butyramido-5-methylbenzoic acid to form 2-n-propyl-4-methyl-benzimidazole-6-carboxylic acid.
    Type: Grant
    Filed: October 18, 2005
    Date of Patent: May 17, 2011
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: Sundaram Venkataraman, Vijayavitthal Thippannachar Mathad, Srirami Reddy Kikkuru, Srinivasan Neti, Raveendra Reddy Chinta, Muthulingam Arunagiri, Lalitha Kumari Routhu
  • Patent number: 7790886
    Abstract: The present invention is related to crystalline forms of ziprasidone and its hydrochloride salt and an amorphous form of ziprasidone hydrochloride and the process for the preparation thereof. The crystalline forms and amorphous form of the invention are suitable for pharmaceutical purposes in the treatment of psychosis. The processes of the invention are simple, non-hazardous and commercially suitable.
    Type: Grant
    Filed: January 5, 2009
    Date of Patent: September 7, 2010
    Assignees: Dr. Reddy's Laboratories, Inc., Dr. Reddy's Laboratories Limited
    Inventors: Manne Satyanarayana Reddy, Thirumalai Rajan Srinivasan, Venka Bhaskara Rao Uppala, Mummadi Venkatesh, Akundi Surya Prabhakar
  • Patent number: 7777037
    Abstract: A process for preparing ziprasidone having low levels of keto ziprasidone and hydroxy ziprasidone impurities.
    Type: Grant
    Filed: October 26, 2005
    Date of Patent: August 17, 2010
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: Sundaram Venkataraman, Uppala Venkata Bhaskara Rao, Venkateswarlu Muvva, Vijayawardhan Chitta
  • Patent number: 7772398
    Abstract: A process for preparation of crystalline Form I of clopidogrel hydrogen sulphate, that include separating the crystalline Form I of clopidogrel hydrogen sulphate from a solution of clopidogrel freebase in a solvent, which is 2-propanol or 2-butanol is provided.
    Type: Grant
    Filed: March 11, 2005
    Date of Patent: August 10, 2010
    Assignees: Dr. Reddy's Laboratories, Inc., Dr. Reddy's Laboratories Limited
    Inventors: Eswaraiah Sajja, Raghupathi Reddy Anumula, Bhaskara rao Venkata Uppala
  • Patent number: 7700779
    Abstract: The present invention is related to novel polymorph of Fexofenadine and Fexofenadine hydrochloride of formula 1 and process of preparation thereof. The present invention is also directed to provide pure novel polymorphs of Fexofenadine and its hydrochloride by a simple process which is cost effective, commercially viable and environment friendly.
    Type: Grant
    Filed: July 31, 2001
    Date of Patent: April 20, 2010
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: M. Satyanarayana Reddy, S. Thirumalai Rajan, U. V. Bhaskara Rao
  • Patent number: 7659406
    Abstract: A process for preparing valsartan.
    Type: Grant
    Filed: January 3, 2006
    Date of Patent: February 9, 2010
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: Pratap Reddy Padi, Satya Narayana Bollikonda, Ananda Mohan Jasty, Suma Latha Yasareni, Vishal Dayaram Parmar
  • Patent number: 7612098
    Abstract: A hydrate of esomeprazole magnesium in the form of an amorphous solid is provided. Methods of preparation and use of, as well as formulation containing the hydrate of esomeprazole magnesium in the form of an amorphous solid are also provided.
    Type: Grant
    Filed: August 28, 2003
    Date of Patent: November 3, 2009
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: Manne Satyanarayana Reddy, Muppa Kishore Kumar, Koilkonda Purandhar, Keshaboina Sreenath
  • Patent number: 7547785
    Abstract: A process for preparing topotecan.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: June 16, 2009
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: Venkata Raghavendra Acharyulu Palle, Sekhar Munaswamy Nariyam, Lankeshwara Rao Matti
  • Patent number: 7531673
    Abstract: A process for making amino acid amides, comprising reacting an amino acid, or acid salt of an amino acid, with a halogenating agent, or with a substance that reacts with carboxylic acids to form a leaving group, to form an intermediate, then reacting the intermediate with ammonia. When the amino acid or acid salt is enantiomerically pure, the amide will be a stereoisomer. An amide made by the process can be used to form levetiracetam.
    Type: Grant
    Filed: February 16, 2005
    Date of Patent: May 12, 2009
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: Palle V. R. Acharyulu, C. M. Haricharan Raju
  • Patent number: 7501515
    Abstract: The present invention relates to a novel polymorphic form of 17-?-(N-ter.butyl carbamoyl)-4-aza-5-?-androst-1-en-3-one (Finasteride) of the Formula (I) and processes for preparing the form.
    Type: Grant
    Filed: March 15, 2004
    Date of Patent: March 10, 2009
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: M. Satyanarayana Reddy, S. T. Rajan, M. V. N. Brahmeshwara Rao, K. Vyas, S. Vishnuvardhana Reddy, K. Shashi Rekha
  • Patent number: 7488729
    Abstract: The present invention is related to crystalline forms of ziprasidone and its hydrochloride salt and an amorphous form of ziprasidone hydrochloride and the process for the preparation thereof. The crystalline forms and amorphous form of the invention are suitable for pharmaceutical purposes in the treatment of psychosis. The processes of the invention are simple, non-hazardous and commercially suitable.
    Type: Grant
    Filed: December 4, 2003
    Date of Patent: February 10, 2009
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: Manne Satyanarayana Reddy, Thirumalai Rajan Srinivasan, Venka Bhaskara Rao Uppala, Mummadi Venkatesh, Akundi Surya Prabhakar
  • Patent number: 7476737
    Abstract: Eszopiclone is prepared by reacting zopiclone with an enatiomerically pure di-p-toluoyl tartaric acid, recovering a solid salt, and reacting a solid salt with a base. Zopiclone is prepared by reacting 6-(5-chloropyrid-2-yl)-5-hydroxy-7-oxo-5,6-dihydropyrrolo[3,4-b]-pyrazine with 1-chlorocarbonyl-4-methylpiperazine hydrochloride.
    Type: Grant
    Filed: September 5, 2006
    Date of Patent: January 13, 2009
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: Venkata Naga Brahmeswara Rao Mandava, Sreenadhacharyulu Kandala, Mukunda Reddy Jambula, Raveendra Reddy Chinta
  • Patent number: 7230006
    Abstract: A new crystalline Form III of moxifloxacin monohydrochloride and processes for making the crystalline form as well as compositions, pharmaceutical compositions, and methods utilizing the crystalline form are described.
    Type: Grant
    Filed: April 9, 2004
    Date of Patent: June 12, 2007
    Assignees: Reddy's Laboratories Limited, Reddy's Laboratories, Inc.
    Inventors: Manne Satyanarayana Reddy, Sajja Eswaraiah, Vetukuri Venkata Naga Kali Vara Prasada Raju, Rapolu Rajesh Kumar, Ningam Srinivasreddy, Vedantham Ravindra
  • Patent number: 7189853
    Abstract: The present invention is related to a process for preparing montelukast involving the compound of formula (VI): wherein X?CN or CONH2.
    Type: Grant
    Filed: September 2, 2004
    Date of Patent: March 13, 2007
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: Venkataraman Sundaram, Srinivasan Thirumalai Rajan, Veera Venkata Naga Chandra Sekhar Bulusu, AlokKumar Srivastav, Ravi Kumar Kasturi, Sanjeev Kumar Aavula