Abstract: A composition is provided which is useful for self-tanning skin coloring and is characterized by improved stability, which comprises from about 0.5% to about 20.0% by weight, based on total weight of said composition, of a self-tanning skin coloring agent subject to chemical instability, which is preferably dihydroxyacetone; from about 2.0% to about 40.0% by weight of a polyethoxyglycol, which is preferably ethoxydiglycol; and from about 0.1% to about 15.0% by weight of a polyol comprising a polyhydric compound having at least three hydroxyl groups and at least three carbon atoms, which is preferably D-sorbitol. The self-tanning composition may further optionally contain from about 0.1% to about 8.0% by weight of a water soluble dihydroxyl compound having at least two, and up to eight carbon atoms, which is preferably ethylene glycol; and the self-tanning composition may still further optionally contain an acidifying agent in amount sufficient to maintain the pH of said total composition at from about 3.
Type:
Grant
Filed:
April 18, 2000
Date of Patent:
May 15, 2001
Assignee:
Schering-Plough HealthCare Products, Inc.
Abstract: Since the ferroelectric memory device is a 1T1C type, the size of one memory cell can be smaller than that of a 2T2C type. In this ferroelectric memory device, the reference potential does not have to be generated when data is read.
Abstract: An aqueous nebulizer suspension contains water, mometasone furoate monohydrate, a nonionic surfactant, a soluble salt and optionally a pH buffer. The suspension may be prepared by ultrasonication or jet milling techniques.
Type:
Grant
Filed:
October 6, 1998
Date of Patent:
February 13, 2001
Assignee:
Schering Corporation
Inventors:
David Harris, Joel A. Sequeira, Imtiaz A. Chaudry
Abstract: The invention relates to the novel compound mometasone furoate monohydrate, process for its preparation and pharmaceutical compositions containing said compound.
Type:
Grant
Filed:
April 17, 1995
Date of Patent:
January 30, 2001
Assignee:
Schering Corporation
Inventors:
Pui-Ho Yuen, Charles Eckhart, Teresa Etlinger, Nancy Levine
Abstract: An antihistaminic syrup is stabilized against degradation of the active ingredient, by the addition of and about 0.05 to about 5 mg/mL of an aminopolycarboxylic acid such as a salt of ethylenediaminetetraacetic acid.
Type:
Grant
Filed:
June 1, 1998
Date of Patent:
October 17, 2000
Assignee:
Schering Corporation
Inventors:
Farah J. Munayyer, Frank Guazzo, Elliot I. Stupak, Imtiaz A. Chaudry, Joel A. Sequeira
Abstract: The invention relates to the novel compound mometasone furoate monohydrate, process for its preparation and pharmaceutical compositions containing said compound.
Type:
Grant
Filed:
April 29, 1998
Date of Patent:
October 3, 2000
Assignee:
Schering Corporation
Inventors:
Pui-Ho Yuen, Charles Eckhart, Teresa Etlinger, Nancy Levine
Abstract: A colored sunscreen emulsion which enables the user to more effectively protect against skin damage, by facilitating more complete and uniform coverage of the sunscreen on the skin, comprises:a) at least one particulate ultramarine pigment that imparts a color other than white to the sunscreen emulsion, in amounts such that when the sunscreen emulsion is rubbed into the skin, the color substantially disappears;b) at least one sunscreen active agent in an amount effective to protect skin against the actinic radiation of the sun;c) at least one emulsifier;d) sufficient water to form the colored emulsion; ande) optionally, one or more ingredients from one or more of the following classes: emollients, humectants, dry-feel agents, waterproofing agents, insect repellents, preservatives, antioxidants, chelating agents and fragrances.
Type:
Grant
Filed:
May 26, 1999
Date of Patent:
August 8, 2000
Assignee:
Schering-Plough HealthCare Products, Inc.
Inventors:
James E. McShane, Donathan G. Beasley, Brad Elliott, Thomas A. Meyer
Abstract: The invention relates to suspension aerosol formulations which exhibit stable particle sizes, containing mometasone furoate, about 1 to about 10 weight percent ethanol and 1,1,1,2,3,3,3-Heptafluoropropane as the propellant. A surfactant, such as oleic acid, can also be included. These formulations are suitable for use in metered dose inhalers.
Type:
Grant
Filed:
August 27, 1997
Date of Patent:
May 30, 2000
Assignee:
Schering Corporation
Inventors:
Julianne Berry, Joel A. Sequeira, Imtiaz A. Chaudry
Abstract: The administration of aerosolize particles of mometasone furoate in the form of dry powders, solutions, or aqueous suspension for treating corticosteroid-responsive diseases of the surfaces of upper and/or lower airway passages and/or lungs, e.g., allergic rhinitis and asthma is disclosed.
Type:
Grant
Filed:
March 1, 1999
Date of Patent:
May 2, 2000
Assignee:
Schering Corporation
Inventors:
Joel A. Sequeira, Francis M. Cuss, Keith B. Nolop, Imtiaz A. Chaudry, Nagamani Nagabhushan, James E. Patrick, Mitchell Cayen
Abstract: Low cost sunscreening formulations having SPF values greater than 40 contain homosalate, octyl salicylate or mixtures thereof, in combination with oxybenzone, and optionally further contain octyl methoxycinnamate, avobenzone or mixtures thereof.
Type:
Grant
Filed:
November 25, 1996
Date of Patent:
April 11, 2000
Assignee:
Schering-Plough HealthCare Products, Inc.
Abstract: A colored sunscreen emulsion which enables the user to more effectively protect against skin damage, by facilitating more complete and uniform coverage of the sunscreen on the skin, comprises:a) at least one oil-soluble dye that imparts a color other than white to the sunscreen, in amounts such that when the emulsion is rubbed into the skin, the color substantially disappears;b) at least one sunscreen active agent in an amount effective to protect skin against the actinic radiation of the sun;c) at least one emulsifier;d) sufficient water to form the colored emulsion; ande) optionally, one or more ingredients from one or more of the following classes: emollients, humectants, dry-feel agents, waterproofing agents, preservatives, antioxidants, chelating agents, insect repellents and fragrances.
Type:
Grant
Filed:
May 3, 1999
Date of Patent:
March 28, 2000
Assignee:
Schering-Plough HealthCare Products, Inc.