Abstract: In the disclosed process, an O.sup.2, 2' anhydro-1-(.beta.-D-arabinofuranosyl)thymine is formed by condensing a 2-amino-.beta.-arabinofurano[1',2':4,5,]-2-oxazoline with a compound of the formula ##STR1## wherein R.sub.1 is C.sub.1 -C.sub.4 alkyl; X is halogen or OR.sub.2, wherein R.sub.2 is H, C.sub.1 -C.sub.4 alkyl or phenyl; in the presence of a suitable solvent at about 0.degree. C. to about 150.degree. C. Catalytic agents such as dimethylaminopyridine and triethylamine may also be added to accelerate the reaction.Protected intermediates of the anhydronucleosides and aminooxazolines are also disclosed.

Abstract: A refractory composition is disclosed which consists essentially of sized refractory aggregate including at least 10%, based on the total weight of the composition, MgO containing grain having at least 50% MgO and passing a 5 mesh screen, from about 0.1 to about 1.5%, on the dehydrated basis, of chrome sulfate or sodium sulfate, from about 0.1 to about 1.5% of an organic acid or salt thereof; and up to about 1.1% of a plasticizer.

Abstract: A guide wire for an intravascular catheter is disclosed. In one embodiment, the guide wire has Doppler means positioned on the distal end, with preferred Doppler means being piezoelectric ceramics or piezoelectric polymeric materials, both having electrical leads connected thereto. In another embodiment, the guide wire has a Laser Doppler means.

Abstract: 4-Phenyl-1,2,3,4-tetrahydro-1-naphthalenamine derivatives have been found useful for the treatment of psychosis, inflammation and as immunosuppressants.

Abstract: A series of [N-alkyl-N-(nitro-, alkylsulphonamido, or amino-phenalkyl)amino]-alkyl, alkoxy or alkylthio phenyl derivatives having utility as anti-arrhythmic agents.

Abstract: Dihydropyridines having unsaturated side chains are disclosed. The compounds are useful anti-ischemic and antihypertensive agents.

Abstract: A steerable catheter having a Doppler crystal at the tip to measure the velocity of blood in vivo--and inferentially the blood flow. The catheter includes two passageways, one passageway being exposed to the blood stream with the other passageway containing the electrical leads to the Doppler crystal. The one passageway is dimensioned for receiving a wire guide for accurately manipulating the catheter. Preferably, the catheter incorporates an inflatable angio-balloon operable to distend the blood vessel in the region of a stenosis. Thus, blood flow can be determined in the region of the stenosis before and/or after the vessel is distended. The passageways are preferably defined by a pair of generally concentric tubes with the Doppler crystal doughnut-shaped and sealingly disposed at the tip of the catheter.

Abstract: A method is disclosed for the containment and controlled release of and the substantial reduction of the leaching from the site of application of agricultural chemicals. In the disclosed method, the agricultural chemicals are applied to the soil dispersed in an aqueous gel-forming composition. Novel compositions of the agricultural chemicals dispersed in aqueous gel-forming compositions are also disclosed.

Abstract: An invasive, fluid velocity measuring wire guide particularly adapted and of a size (less than 0.030 inch) for subselective placement in the coronary arterial tree, which includes a Doppler mechanism for determining the blood flow velocity in the region of the distal end of the wire guide. Although the wire guide is particularly adapted for diagnosing coronary arterial disease subselectively; it is of such a size and manipulability to be useful in other blood flow and biological fluid flow analyses. Preferably, the wire guide is flexible and steerable for precise placement. The wire guide includes an elongated wire member having a Doppler crystal attached in longitudinal alignment at its distal end. Electrical leads extend from the Doppler crystal along the wire member to the appropriate test equipment for measuring the fluid flow velocity in the region of the Doppler crystal. Preferred embodiments of the Doppler means include piezoelectric crystals and piezoelectric polymers.

Abstract: A bone cement is disclosed wherein the liquid component contains a therapeutic or diagnostic substance in combination with an emulsifying agent for said substance.

Abstract: A composition for cleaning the gums comprising silica, water and a detergent, said composition having a RDA of less than 20.

Abstract: A steerable catheter having a Doppler crystal at the tip to measure the velocity of blood in vivo--and inferentially the blood flow. The catheter includes two passageways, one passageway being exposed to the blood stream with the other passsageway containing the electrical leads to the Doppler crystal. The one passageway is dimensioned for receiving a wire guide for accurately manipulating the catheter. Preferably, the catheter incorporates an inflatable angio-balloon operable to distend the blood vessel in the region of a stenosis. Thus, blood flow can be determined in the region of the stenosis before and/or after the vessel is distended. The passageways are preferably defined by a pair of generally concentric tubes with the doppler crystal doughnut-shaped and sealingly disposed at the tip of the catheter.

Abstract: The disclosed process uses a vertical remote controlled refractory gunning apparatus to repair damages to the stack, bosh, or hearth of a blast furnace. In the disclosed method, a reusable opening is created in the side of the blast furnace and a gantry, for example, is inserted through the reusable opening. The vertical remote-controlled refractory gunning apparatus is then introduced into the blast furnace via the gantry. In those cases wherein the blast furnace is loaded through a chute, the chute is moved to one side, the gantry is introduced at an angle and the vertical remote controlled refractory gunning apparatus is introduced through the opening.

Abstract: A refractory composition is disclosed which contains from about 0.5 to about 0.5% of an alkali metal phosphate, for example, monosodium phosphate, from about 1.7 to about 5% of an alkali metal polyphosphate, from about 0.1 to about 0.35% of a lime aggregate; from about 0.1 to about 1.5% of a plasticizer, with the balance being a sized refractory aggregate, preferably an MgO-containing grain such as periclase.

Abstract: There is disclosed a bone cement composition comprising (a) a liquid component comprising a monomer of an acrylic ester and (b) a powdered component comprising, based on the weight of the powdered component,(i) from 0 to about 20 percent of a methyl methacrylate homopolymer,(ii) from about 30 to about 60 percent of a methyl methacrylate-styrene copolymer, and(iii) from about 30 to about 60 percent of a methyl methacrylate-butyl methacrylate copolymer.

Abstract: Aqueous gel-forming compositions are prepared by reacting for 1-10 hours at 50.degree.-95.degree. C., melamine, formaldehyde and a sulfurous acid salt with the optional addition of a gel-modifying agent and/or a gelling agent which is added to the composition immediately prior to use.

Abstract: A series of pyridyl or imidazolyl substituted phenyl piperazines having utility as anti-arrhythmic agents is disclosed.

Abstract: Aqueous gel-forming compositions are prepared by reacting for 1-10 hours at 50.degree.-95.degree. C., melamine, formaldehyde and a sulfurous acid salt with the optional addition of a gel-modifying agent and/or a gelling agent which is added to the composition immediately prior to use.

Abstract: Spiro-succinimides are disclosed which are useful as aldose reductase inhibitors and as therapeutic agents for the treatment of complications arising from diabetes. Pharmaceutical compositions containing the spiro- compounds and a method of treating diabetic complications are also disclosed.