Abstract: Antibodies that interact with interleukin-1 receptor type 1 (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL-1R1 are described.

Abstract: The present invention discloses a method of accessing stored information in multi-framed data transmissions, comprising at least one control interface and at least one elastic store, wherein the control interface accesses the elastic store through a mailbox communications method.

Abstract: A media player may occasionally be unable to play or continue to play a particular item of media. When that occurs, the media player outputs an error indication that is related to the type of media that the problem media item is representative of. For example, if the problem item is a movie, then the media player may display an error indication having the appearance of broken movie film. If the problem media item is music, then the media player may display an error indication having the appearance of a broken compact disc (“CD”). Thus whatever the type of media that is not playing, the media player outputs an error indication that is appropriate for that type of media. The error indications output by the player are therefore context-based or media-appropriate.

Abstract: A method and device for wire termination on stators (1) wherein the wire (15) is wound about poles (6) distributed by a flyer (10), guided by shrouds (16) that move radially with respect to the stator (1) overlapping the respective pole (6). Wire termination operations are provided on the wire ends (15) into the terminals (4) with the aid of the flyer (10), carried out by an apparatus equipped with a termination device (20), comprising a first deflector (21), a second deflector (22), a blade (23), and a clamp formed by a movable gripper (24) and a fixed gripper (25). The movable gripper is suitable for closing onto the fixed gripper for gripping the wire (15). The device (20) can carry out the steps of catching, moving, introducing and cutting the wire (15) with movements parallel to its own axis (27), or to the axis (7) of the stator (1).

Abstract: A dual-port static random access memory (SRAM) includes a multitude of programmable delay elements disposed along the paths of a number signals used to carry out read, write or read-then-write operations. At least one of the programmable delay elements controls the timing margin between a pair of clock signals that trigger a read/write enable signal. A second programmable delay element coarsely adjusts the delay of a first signal associated with a dummy bitline. A third programmable delay element finely adjusts the delay of a second signal associated with the dummy bitline. A fourth programmable delay element controls the delay of a signal used to reset the read/write enable signal. During a read operation, the voltage level of the second signal is used as an indicator to activate the sense amplifiers. During a write operation, the voltage level of the second signal is used to control the write cycle.

Abstract: Digital compressed codes, associated with advertisements enable a user to selectively record additional information, which would be broadcast on a television channel at a later time. The advertisement could be print advertisement or broadcast advertisement on television or radio. The user enters the digital code (I code) associated with an advertisement into a unit with a decoding means which automatically converts the code into CTL (channel, time and length). The unit within a twenty four hour period activates a VCR to record information on the television channel at the right time for the proper length of time. The decoded channel, time and length information can be communicated directly to a VCR and used by the VCR directly to automatically activate the VCR to record a given television information broadcast corresponding to the communicated channel, time and length.

Abstract: The disclosure provides, in part, compositions of perfluoro polyether compounds and associated methods for producing cellular labels for tracking cells by MRI and methods for labeling, detecting and quantifying cell numbers in vivo.

Abstract: The systems and methods provide or use a brace for patient's limb that includes, among other things, a non-inflatable, rigid, lower housing for supporting the sole of a patient's foot, and an inflatable load-bearing upper housing that is affixed to the lower housing. The brace may be adjustable and configured to be fitted to patients having limbs of differing sizes, to allow the patient to obtain a more closely fitted brace.

Abstract: Systems and methods for identifying a recorded video program are provided. The method may include recording a video and identifying the video as lacking desirable recording attributes. A future occurrence of a transmission of the video may be automatically selected in response to the identification of the video as lacking desirable recording properties. The future occurrence of the transmission of the video may be automatically re-recorded.

Abstract: Presently described is a system and method for switching multimedia data communications, including but not limited to Voice over IP (VoIP) telephony, cable TV, digital audio and video. The system utilizes a single, integrated device to provide all PacketCable-compliant functionality, including enhanced user privacy, compliance with CALEA, E911 and other mandated services not available in conventional distributed PacketCable systems. High speed and efficient, low cost operation are provided by means of an optimized data unit encapsulation scheme for internal switching and routing. A proprietary fiber optic backplane and removable optical connectors are used to enable lightspeed internal communications hot-swapping of components. Furthermore, the present system is extensible to all forms of digital data switching and is secure, resistant to Denial of Service attacks, and fault-resilient.

Abstract: The present invention relates to multivalent polypeptides comprising at least two fibronectin scaffold domains connected via a polypeptide linker. The invention also relates to multivalent polypeptides for use in diagnostic, research and therapeutic applications. The invention further relates to cells comprising such proteins, polynucleotide encoding such proteins or fragments thereof, and to vectors comprising the polynucleotides encoding the innovative proteins.

Abstract: This application describes methods and compositions for detecting and treating vimentin-associated neoplasia. Differential methylation of the vimentin nucleotide sequences has been observed in vimentin-associated neoplasia such as colon neoplasia.

Abstract: Equalizer circuitry on an integrated circuit (“IC”) includes a plurality of NMOS equalizer stages connected in series. Each NMOS stage may include folded active inductor circuitry. Each NMOS stage may also include various circuit elements having controllably variable circuit parameters so that the equalizer can be controllably adapted to perform for any of a wide range of high-speed serial data signal bit rates and other variations of communication protocols and/or communication conditions. For example, each NMOS stage may be programmable to control at least one of bandwidth and power consumption of the equalizer circuitry. The equalizer may also have a first PMOS stage that can be used instead of the first NMOS stage in cases in which the voltage of the incoming signal to be equalized is too low for an initial NMOS stage.

Abstract: Systems and methods for integrating graphic animation technologies with fantasy sports contest applications are provided. This invention enables a fantasy sports contest application to depict plays in various sporting events using graphic animation. The fantasy sports contest application may combine graphical representation of real-life elements such as, for example, player facial features, with default elements such as, for example, a generic player body, to create realistic graphic video. The fantasy sports contest application may provide links to animated videos for depicting plays on contest screens in which information associated with the plays may be displayed. The fantasy sports contest application may play the animated video for a user in response to the user selecting such a link. In some embodiment of the present invention, the fantasy sports contest application may also customize animated video based on user-supplied setup information.

Abstract: The present invention relates to compounds that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention. The invention further relates to processes for preparing these compounds.

Abstract: A pulse-width modulated backlight control for a video display restarts the pulse-width modulated pulse train on occurrence of a video refresh pulse. In order to prevent an undesirable momentary increase in brightness in the event that the last pulse of the pre-refresh pulse train occurs too close to the first pulse of the post-refresh pulse train relative to the normal pulse interval, the width of the first pulse following refresh may be reduced from a first value determined by the desired brightness to a second value that bears the same proportion to the first value that the interval between the beginning of the previous pulse and the occurrence of the refresh pulse bore to the normal pulse interval. In that way, the duty cycle during the shortened pulse interval is the same as during a normal pulse interval, avoiding or minimizing perceptible increase in backlight brightness.

Abstract: Systems and methods for that allow for the creation and management of a centralized gift registry are described. A retailer-specific registry is imported into the centralized gift registry. A gift list is created and displayed. Gift givers may select a gift from the gift list of the centralized gift registry. In one embodiment, when a purchase of a gift occurs, the gift list is updated. Updates to gifts are sent between the centralized gift registry and the retailer-specific registries, such that the gifts common to these registries are synchronized. This synchronization may involve the use of APIs at the centralized gift registry or the retailer-specific registries. The centralized gift registry system automatically searches for all retailer-specific registries pertaining to the gift registrant. The centralized gift registry system may request a retailer's system for information on gift items of a respective retailer-specific registry.

Abstract: In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.

Abstract: Presented herein are systems and methods for processing sound signals for use with electronic speech systems. Sound signals are temporally parsed into frames, and the speech system includes a speech codebook having entries corresponding to frame sequences. The system identifies speech sounds in an audio signal using the speech codebook.

Abstract: A system and method for allocating trades of financial instruments among multiple accounts comprising aggregating orders, wherein each order is associated with an account, and wherein each order has an original order size; allocating an executed order based on the aggregated order in a phase I allocation, wherein the phase I allocation is allocated on a pro-rata basis based on the original order size for each account, except for those accounts that would receive an amount less than a minimum allocation; allocating a remainder from the phase I allocation in a phase II allocation, wherein the phase II allocation is allocated among selected accounts in an amount greater than or equal to the minimum allocation or an amount that fills the original order size; repeating the phase II allocation until a remainder from the phase II allocation is less than the minimum allocation; and allocating a reminder from the phase II allocation in a phase III allocation according to predetermined criteria.