Abstract: A dorsal night splint has dynamic adjustable features that allow the patient to adjust the splint while in use to control the stretching of the plantar fascia and Achilles. A semi-rigid flexible frame is included along with a tightening strap that is anchored to the frame and by which the patient can tension the strap and adjust the structure of the frame to fit the patient's desired therapeutic or prophylactic needs.

Abstract: The present invention relates to an interactive media guidance application that provides improved searching functionality for media information, such as media program listings, media programming information, celebrity information, and other related media information. Search objects may be defined in the entertainment context and applied to media information to enable efficient searching. Different types of media information may be categorized to enable proper organization of search results. A search object query may be performed based on a user entered search expression and the results may be a vertical slice through the organized categories of media information. User submitted tags may also be applied to the media information and used to search the media information. Atomic searching may be enabled for more generic search expressions, whereby an atomic search object is associated with a personalized atomic search algorithm comprised of individual searches.

Abstract: Multiple channel maps are embedded in a television transmission and the appropriate channel corresponding to the particular television service used by the viewer is downloaded for use with the television receiver. Each channel map is accompanied by a channel map identifier which identifies the source of the television transmission and a geographic identifier. The source of a television transmission is automatically detected by monitoring the radio-frequency spectrum allocations of telecast stations. The geographic area identifier is determined by comparison with a user inputted geographic area identifier. The channel map having a channel map identifier corresponding to the detected television transmission source and the user inputted geographic area identifier is downloaded and stored for future use.

Abstract: In certain aspects, the present invention provides compositions and methods for modulating (promoting or inhibiting) growth of a tissue, such as bone, cartilage, muscle, fat, brown fat and/or neuronal tissue and for treating metabolic disorders such as diabetes and obesity, as well as disorders associated with any of the foregoing tissue.

Abstract: The application describes compositions and methods for regulating body weight, in particular, for treating obesity and obesity-associate disorders. The application also provides methods of screening compounds that modulate activity of GDF3. These compositions and methods are also useful in treating diseases associated with abnormal activity of GDF3.

Abstract: Systems and methods are presented for presenting advertisements to users of a fantasy sports contest application. Advertisements are displayed in conjunction with fantasy sports contest information and may be interactive in nature. The advertisements may be used to inform the user of prizes being awarded for performance in the fantasy sports contest, including prizes being awarded for performing in an instant scoring opportunity based on real-time action in a related sports broadcast. The advertisements may be intelligently scheduled around certain events in a related sports broadcast to take advantage of user purchasing habits. The advertisements may be selected according to a user profile. The user profile may include information on the user's demonstrated interests, which may be determined using the user's preferences in the fantasy contest, prior television viewing habits, and other suitable information. The advertisements may be targeted to the user's specific geographic location.

Abstract: Systems and methods for generating and/or displaying personalized video content are provided. In some embodiments, a video asset made up of a set of frames, including a preliminary frame with an object region, is received at user equipment. A media element is identified and transmitted to a remote server, where it is processed to produce a modified version of the media element and then transmitted back to the user equipment. The video asset is displayed at the user equipment, except that a modified frame incorporating the modified version of the media element is displayed in place of the preliminary frame. The modified version of the media element is incorporated in an area of the modified frame corresponding to the object region of the preliminary frame.

Abstract: Interactive program guide systems and related processes are provided which can automatically tune a television, or program a VCR, based on program selections made from program schedule information displayed on a television or other suitable video monitor. The interactive program guide is preferably implemented using a microprocessor-controlled set-top box that is coupled to the viewer's television set. The set-top box receives program schedule information and software from a headend telecasting center. Preferably, program schedule information for the current day and at least six subsequent days is stored in a memory within the set-top box. The interactive program guide provides a display mode for allowing the viewer to apply a restrictive search selection criterion and a nonrestrictive sort attribute to the program schedule information.

Abstract: Improved electron beam sterilization apparatus and shielding techniques for use in are provided. A controller modulates an electron beam when sterilizing an interior to an object to ensure that adequate dose is received. Sterilization carousels are configured with input/discharge feeds to reduce the possibility of humans being exposed to dangerous levels of radiation. The system reduces the amount of shielding required to thereby lower cost of installation.

Abstract: A system for predicting healthcare financial risk including the process of accessing patient data associated with one or more patents, accessing geographic and healthcare system data, filtering the patient data, geographic data, and healthcare system data into clean data, and applying a predictive risk model to the clean data to generate patient profile data and to identify a portion of the patients associated with a level of predicted financial risk.

Abstract: Systems and methods for managing the distribution of on-demand media in an interactive television application are provided. An interactive television application may receive a request for on-demand media from a user. The interactive television application may provide an option to the user for the transmission of the on-demand media. Such options may include, for example, an option to request a reduced-bandwidth version of the on-demand media, an option to schedule a future time for presentation of the on-demand media, an option to download the on-demand media to a recording device, and an option to check the availability of the on-demand media. A reduced price for transmission of the on-demand media may be provided to the user.

Abstract: Signal detection circuitry for a serial interface oversamples the input—i.e., samples the input multiple times per clock cycle—so that the likelihood of missing a signal is reduced. Sampling may be done with a regenerative latch which has a large bandwidth and can latch a signal at high speed. The amplitude threshold for detection may be programmable, particularly in a programmable device. Thus, between the use of a regenerative latch which is likely to catch any signal that might be present, and the use of oversampling to avoid the problem of sampling at the wrong time, the likelihood of failing to detect a signal is greatly diminished. Logic, such as a state machine, may be used to determine whether the samples captured s do or do not represent a signal. That logic may be programmable, allowing a user to set various parameters for signal detection.

Abstract: Clock data recovery (CDR) circuitry of a high-speed serial interface on a programmable integrated circuit device toggles, during the electrical idle period of the receiver of the interface, between its “lock-to-reference” (“LTR”) state and its normal “lock-to-data” (“LTD”) state. Whenever during this toggling mode the CDR circuitry toggles to the LTD state, it remains in that state for a predetermined interval and then returns to the LTR state, unless, while it is in the LTD state, it receives a signal from elsewhere in the receiver that data have been received and byte synchronization has occurred. The predetermined toggling interval preferably is long enough to obtain an LTR lock to minimize frequency drift, but short enough to avoid unnecessary delay in detection of the synchronization signal. Preferably, this interval is programmable by the user within limits determined by the characterization of the programmable device. Unreliable analog signal detection is thereby avoided.

Abstract: Systems and methods for navigating a three-dimensional (3D) media guidance application are provided. A first selectable media guidance object may be displayed on a screen that when viewed through the stereoscopic optical device may appear in a first plane. A second selectable media guidance object may be displayed on the screen that when viewed through the stereoscopic optical device may appear in a second plane. The first and second planes may be perceived to intersect an axis normal to the display in different locations. A user selection of at least one of the first and second selectable media guidance objects may be received. An action of moving a cursor in 3D space or selecting one of the selectable media guidance objects displayed in the 3D space may be performed based on the user selection. The user selection may be performed with an input device having an accelerometer.

Abstract: A programmable logic device can be configured as a fractional rate resampling filter capable of performing downsampling prior to upsampling without modifying the overall filter response. Input data may be received at a first sample rate and may be downsampled to generate downsampled data. Portions of the downsampled data may be respectively output to different filtering paths. Each filtering path may include a cluster of filter components that corresponds to different subfilters of the overall filter response and may be operable to receive and process the different portions of the downsampled data. Outputs of each cluster may be combined to generate output data at a second sample rate. The resampling filter structure can reduce the number of multiplier circuits used by allowing time-division multiplexing among different filter components.

Abstract: The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides processes for preparing the compounds, pharmaceutically acceptable compositions comprising the compounds, and methods of using the compounds and compositions in the treatment of various disease, conditions, or disorders.

Abstract: Providing ASIC equivalents of FPGAs is facilitated and made more efficient and economical by using an ASIC architecture including a plurality of so-called hybrid logic elements (“HLEs”), each of which can provide a portion of the full functionality of an FPGA logic element (“LE”). The functionality of each FPGA LE implementing a user's logic design can be mapped to one or more HLEs without re-synthesis of the user's logic. Only as many HLEs as are necessary are used to perform the functions of each LE. The one-for-one equivalence between each LE and either (1) one HLE or (2) a group of HLEs facilitates mapping (without re-synthesis) in either direction between FPGA and ASIC designs.

Abstract: In certain aspects, the present invention provides BMP10 propeptides for use in treating a variety of disorders including heart disorders and other disorders associated with unwanted activity of the mature BMP10 polypeptide. The present invention also provides methods of screening compounds that modulate activity of BMP10.

Abstract: Hybrid antibodies and/or hybrid antibody fragments and methods of making them are provided. In one embodiment the hybrid antibodies and/or hybrid antibody fragments 5 contain heavy and/or light variable regions that contain two or more framework regions derived from at least two antibodies. In another embodiment, at least two of the framework regions are classified in the same germline gene family. In one embodiment, at least two framework regions are classified in the same germline gene family member. The hybrid antibodies or hybrid antibody fragments may contain human framework regions and 10 nonhuman CDRs.

Abstract: Systems and methods for presenting search results based on relevancy in an interactive media guidance application are disclosed. After performing a user-initiated or automatic search for media content, the interactive media guidance application determines which of the hits are most relevant to the user. The guidance application then displays, or visually identifies, the relevant items. Some embodiments employ using different display arrangements based on the number of relevant items. Some embodiments display the relevant items in recommendation lists or hot lists.