Abstract: A fishing board game to assist in anglers learning the fishing requiremtns in various areas of fishing, such as local fishing regulations, legal sizes, legal limits, boating safety.
Abstract: Disclosed is a method of manipulating the carboxamide functionality in a catalytic manner. The method includes the steps of reacting amides with or without amines in the presence of various types of metal catalysts, at a temperature of about 250° C. or less.
Type:
Grant
Filed:
February 24, 2004
Date of Patent:
December 26, 2006
Assignee:
Wisconsin Alumni Research Foundation
Inventors:
Shannon S. Stahl, Samuel H. Gellman, Sarah E. Eldred
Abstract: Disclosed is a combustion engine. The engine includes a combustion chamber (40), which is delimited at one end by a head (41) and delimited at a second end by a piston (1). The piston is arranged on a connecting rod (3) via a piston pin (2). A body (1;8;52) with a delimiting surface (8A) is movable in relation to the piston pin (2) and facilitates a variable volume in the combustion chamber (40). A compression spring (10), acts on the surface (8A) with a spring force in the direction of the combustion chamber (40). The engine further includes a pressure chamber (11) that can be supplied with hydraulic oil from a pressure source via a feed duct (12,13), which pressure chamber (11) is able to cause hydraulic movement of the moveable delimiting surface (8A) with the aim of being able to adjust the size of the combustion chamber depending on the combustion pressure.
Abstract: A modular fluid handling device includes at least one block having opposing block faces shaped as tessellating regular polygons, and a series of block sides therebetween. Each block includes a central bore extending between the block faces, and channels extending into the block sides and intersecting with the central bore. The blocks may be rapidly horizontally and/or vertically affixed with their channels and/or bores in communication to form a fluid handling device having the desired configuration (e.g., with the channels/bores forming a desired process flow path, fluid circuit, or the like). Inserts complementarily fit within the bores of selected blocks can then bear components such as valves, filters, turbines or stirrers, heating or cooling elements, pumps, sensors, or other equipment, so that a block can be adapted to fulfill desired purposes by simply installing the desired inserts.
Abstract: A composite material that includes from about 18 wt % to about 22 wt % of a thermosetting polymeric resin; and from about 82 wt % to about to about 78 wt % of an inorganic filler, wherein the inorganic filler comprises a mixture of particles wherein about 20 parts by weight of the mixture has an average particle size of about 10 ?m or larger, about 15 parts by weight of the mixture has an average particle size of from less than 10 ?m to about 5 ?m, and about 10 parts by weight of the mixture has an average particle size of from about 3 to about 1 ?m.
Abstract: The present invention provides a self-adhesive tip guide application device for applying tip guides during a French manicure. The present invention allows the user to use both hands in applying the guides to a nail. The device includes an elongated frame having a series of arms extending substantially perpendicularly away from the frame. Each arm contains at least one releasably secured arch-shaped tip guide. The frame also contains a releasably-secured release liner. When removed, the frame can be secured to any surface, thereby more easily allowing the user to apply the guides to the nail.
Abstract: A connector for affixing cables (e.g., of the type having wires bundled within a corrugated cover) within an electrical or other junction box has a body with a first end into which the cable cover (and the wires therein) may be inserted, and a second end configured to affix to the entry of a junction box, and which is configured to allow the wires of the cable to leave the connector and extend into the junction box. The connector has an engagement member thereon with one or more engagement legs which extend into the body of the connector, and into the internal passage of the connector body into which the cable is fit, to engage the cable cover and fix the cable to the connector body.
Abstract: A testing device allows a test engine (such as a single-cylinder test engine) to experience the air exchange characteristics of a multi-cylinder test engine having a greater number of cylinders. The test engine receives air from an air source (such as the atmosphere) through the interior passage of an air intake adapter, wherein valves on the passage walls separate the interior passage from a negative or positive pressure source. A processor (such as a computer) may actuate the valves to allow air to be pulled from the passage to simulate the effect of air intake into additional virtual cylinders (i.e., cylinders that would operate in tandem with the cylinder(s) of the test engine if the test engine had a greater number of cylinders), and/or to simulate the effect of forced air induction (i.e., turbocharging or supercharging).
Type:
Grant
Filed:
February 23, 2005
Date of Patent:
October 17, 2006
Assignee:
Wisconsin Alumni Research Foundation
Inventors:
John J. Moskwa, John L. Lahti, Matthew W. Snyder
Abstract: The invention relates to a composite material which is to be used in sliding bearings and comprises a metallic support (1) and at least one reinforcement material having an open structure (2). Said support (1) and reinforcement material (2) are connected to each other by means of a metallic connection. An overlay (4) which is a polyethylene(PE)-based layer is provided on the reinforcement material (2) as an additional layer.
Abstract: Disclosed are triaryl cationic compounds that exhibit broad spectrum antibiotic and antifungal activity, pharmaceutical compositions containing the compounds, and methods of treating bacterial and fungal infections using the compounds. The compounds were initially isolated by screening a 25,000-member bacterial artificial chromosome (BAC) library of environmental (eDNA) from soil. At least one clone produced a dark brown melanin-like compound that was found to have antibiotic activity. The compounds were isolated and synthesized de novo. From within the positive clone, a single open reading frame that shares extensive sequence similarity with members of the 4-hydroxyphenylpyruvate family of enzymes was found to be necessary and sufficient to confer the production of at least one of the subject compounds on E. coli.
Type:
Grant
Filed:
August 8, 2003
Date of Patent:
October 3, 2006
Assignee:
Wisconsin Alumni Research Foundation
Inventors:
Jo E. Handelsman, Robert M. Goodman, Doreen E. Gillespie, Alan D. Bettermann, Jon C. Clardy, Sean F. Brady
Abstract: The present invention is based on the isolation of a gene coding for streptokinase from Streptococcus equisimilis (ATCC 9542), its cloning, and expression in E. coli. Two different strategies were carried out for the production of enzymatically-active streptokinase. In the first strategy, streptokinase was expressed as an inclusion body without its signal sequence followed by purification, solubulization, and renaturation to obtain an active preparation. The purified enzyme was formulated and lyophilized. In the second strategy, enzymatically-active streptokinase is secreted into the culture medium. The enzyme was purified, formulated and lyophilized.
Abstract: Disclosed is a method of measuring affinity of a test compound for a receptor protein. The method includes the steps of providing a receptor-ligand complex comprising a receptor and a quinoxaline derivative ligand bound thereto; then contacting the receptor-ligand complex with a test compound, thereby yielding a receptor-test compound complex and an amount of free quinoxaline derivative; and then measuring the amount of the free quinoxaline derivative generated as a result of the previous step. In this fashion, the affinity of the test compound for the receptor can be determined.
Abstract: Friction stir welding is enhanced by preheating of the workpiece with an electrical arc, such as an arc applied by a common gas-tungsten arc welding (GTAW) torch. As the arc is moved about a path on the workpiece, it preheats or partially welds the path, with the friction stir welding head following along the path to complete the weld.
Abstract: A sewing machine is provided which is capable of sewing reinforcing wire to tubular grafts in order to form stent grafts. A bobbin (which may be seated in a shuttle) carries a bottom thread through the bore of the tubular graft and forms a stitch in combination with a top thread carried on a needle which pierces the graft wall.
Type:
Grant
Filed:
May 1, 2002
Date of Patent:
July 11, 2006
Assignee:
Anson Medical Limited
Inventors:
Peter Phillips, Adrian Michael Woodward, Andrew Richard Buchanan Halket, Gail Beaton, Carl John Perks, Clive Graham Angel, Timothy Faulkner Frost
Abstract: The disclosed invention is a pincer tool comprising two opposably attached arms, one arm ending in an least substantially transparent sight-piece and the other arm ending in a positioning surface comprising at least one indentation well, whereby an item to be viewed such as jewelry or other small items are held in position by the sight-piece, thereby allowing the item to be viewed from directly above the sight-piece.
Abstract: Disclosed are methods for making surface plasmon resonance-capable arrays wherein molecules, such as proteins or nucleic acids, or cells, are adhered to a metal substrate. The metal substrates are modified by depositing an ?-modified alkanethiol monolayer to the substrate and then contacting the ?-modified monolayer with a heterobifunctional linking compound. Biomolecules or cells can then be attached to the heterobifunctional linking compound. Also disclosed are arrays wherein glutathione-containing molecules are immobilized on the substrate and GST-containing molecules are then specifically immobilized onto the substrate, taking advantage of the affinity between glutathione and GST.
Type:
Grant
Filed:
March 15, 2002
Date of Patent:
June 27, 2006
Assignee:
Wisconsin Alumni Research Foundation
Inventors:
Robert M. Corn, Emily A. Smith, Bernard Weisblum, Matthew G. Erickson, Andrew T. Ulijasz, Matthew J. Wanat
Abstract: A pet waste collection device has a pair of opposing jaws movable between a closed jaw state and an open jaw state, and a liner bag may be situated about the jaws so that closure of the jaws about pet waste encases the waste within a bag. The jaws do not simply pivot into a closed state, and rather they travel toward each other in a path substantially parallel to the surface upon which the waste rests to close about the waste, and they then retract. Opposing shells which open and close about the jaws may strip the bag from the jaws when the jaws are closed about the waste.
Abstract: Disclosed is a method for sequencing and amplifying nucleic acid templates wherein a degenerate primer with a fixed sequence region and a random sequence region is utilized. By determining the statistical expectancy of the fixed sequence in the nucleic acid template, this determines the average length of a nucleic acid template that can be sequenced. During the annealing of such a primer with the nucleic acid template, the fixed sequence determines where the complete primer binds by binding to its complementary sequence on the nucleic acid template. The random sequence regions of the primers make it possible for the presence of a unique sequence adjacent to the fixed sequence to be present, thus providing a primer with full complementarity with the nucleic acid template.
Abstract: A tubular graft/stent includes a tubular sheath (10) having at intervals along its length a plurality of ring-like rigid members (11), which are attached to the sheath around their respective circumferences and are made of a shape memory material, so that when the members (11) change shape the sheath (10) adopts a new cross section in conformity with them along its whole length. The members may be discontinuous to allow the adoption of a contracted shape in the martensitic phase and an expanded shape in the austenitic phase. A graft may also have a side tube (14) which can be inverted so as to be housed within the sheath.