Patents Represented by Law Firm Sprung, Horn, Kramer & Woods
  • Patent number: 6077659
    Abstract: An improved process is disclosed for photodynamically inactivating viruses in red blood cell containing compositions by adding vitamin E or a derivative thereof, such as Trolox, to the red blood cell and photosensitizer containing composition prior to irradiation. Addition of vitamin E or derivative thereof is protective of the red blood cells but not the viruses to be inactivated. Cells irradiated in this manner exhibit reduced leakage of potassium ion, and reduced loss of negative charges from the cell membrane compared to cells treated in the absence of vitamin E or derivative. Red blood cells sterilized by this method are better preserved during storage and their life-time in the circulation in vivo is enhanced.
    Type: Grant
    Filed: November 16, 1994
    Date of Patent: June 20, 2000
    Assignee: New York Blood Center, Inc.
    Inventors: Ehud Ben-Hur, Shanti Rywkin, Bernard Horowitz
  • Patent number: 6075165
    Abstract: Process for the preparation of polyhalogenated benzotrifluorides, benzotrichlorides and benzoyl chlorides and new trihalogeno-benzotrichlorides and -benzoyl chloridesPolyhalogenated benzotrifluorides can be reacted with chlorides from the series of Friedel-Crafts catalysts to give the corresponding benzotrichlorides, which can be hydrolysed by water in the presence of iron(III) chloride to give the corresponding benzoyl chlorides. These are suitable as intermediate products for the preparation of active compounds for medicaments and feed additives.
    Type: Grant
    Filed: June 26, 1996
    Date of Patent: June 13, 2000
    Assignee: Bayer Aktiengesellschaft
    Inventors: Albrecht Marhold, Peter Andres
  • Patent number: 5981163
    Abstract: The present invention concerns the product produced by inactivating extracellular or intracellular pathogenic virus in a biological composition without incurring substantial disruption or inactivation of cells and without significant loss of labile proteins or other valuable biological components also contained therein, the inactivation process comprising subjecting said composition to a virucidally effective amount of irradiation in the presence of (a) a mixture of a compound that quenches type I photodynamic reactions and a compound that quenches type II photodynamic reactions or (b) a bifunctional compound that is capable of quenching both type I and type II reactions, to thereby inactivate said virus while retaining functionality of said composition. The composition is advantageously subjected to the irradiation and the mixture of compounds or bifunctional compound in the presence of an irradiation sensitizer.
    Type: Grant
    Filed: December 23, 1994
    Date of Patent: November 9, 1999
    Assignee: New York Blood Center, Inc.
    Inventors: Bernard Horowitz, Bolanle Williams, Henrietta Margolis-Nunno, Sing N. Chin
  • Patent number: 5939441
    Abstract: The invention relates to new substituted pyridylpyrazoles of the general formula (I) ##STR1## in which n represents the number 0, 1 or 2,to a plurality of processes for their preparation, to their use as pesticides and for combating arthropods, and to a new intermediate.
    Type: Grant
    Filed: April 18, 1995
    Date of Patent: August 17, 1999
    Assignee: Bayer Aktiengesellschaft
    Inventors: Jorg Stetter, Bernd Alig, Albrecht Marhold, Norbert Mencke, Klaus Mrusek, Andreas Turberg
  • Patent number: 5836699
    Abstract: A roll-formed sliding surface bearing bushing is circular in an installed state and has a butt joint which extends throughout the width of the bushing and is closed in an installed state. To ensure a backlash-free bearing arrangement, the bushing has on its outside peripheral surface a trapezoidal profile, which includes an angle of 1.degree. to 30.degree. with the plane which contains the longitudinal axis of the bushing.
    Type: Grant
    Filed: September 27, 1995
    Date of Patent: November 17, 1998
    Assignee: Kolbenschmidt Aktiengesellschaft
    Inventors: Karl Back, Karl Becker, Wolfgang Bickle, Thomas Storch
  • Patent number: 5827613
    Abstract: Articles having a diamond-like protective film formed thereon, each comprising a substrate of a material selected from the group consisting of alloys containing at least Co, Ni, or Fe, ceramics, and glass and which has only a slight affinity for a diamond-like thin film, an Mo film formed on the substrate, and a diamond-like thin film formed further thereon. Such articles are manufactured by a method which comprises holding a grid made of Mo close to the surface of the substrate, bombarding the grid and the substrate surface with a bombarding gas consisting of inert gas atoms of Ar or the like, thereby removing contaminants from the surface and depositing Mo atoms on the substrate surface to form an Mo film thereon, ionizing a low-molecular-weight hydrocarbon or a feed gas capable of producing a low-molecular-weight hydrocarbon upon decomposition or reaction, and then accelerating the resulting ions and depositing the same on the Mo film to form a diamond-like film thereon.
    Type: Grant
    Filed: March 10, 1994
    Date of Patent: October 27, 1998
    Assignee: TDK Corporation
    Inventors: Masatoshi Nakayama, Masanori Shibahara
  • Patent number: 5773630
    Abstract: N-Substituted cyclic imides are obtained by reacting a cyclic acid anhydride with an amine in the presence of a solvent and an acid catalyst at 80.degree. to 200.degree. C. and with removal of the water formed, it being particularly advantageous to carry out this reaction in the presence of a stabilizer and an inert, dipolar aprotic cosolvent, optionally to add an inert organic solvent of low or zero polarity to the reaction mixture present after the reaction, to add a non-aqueous base in an amount of 0.5 to 50% by weight, based on the cyclic anhydride of the formula (II) used, and to separate off the precipitate formed to give a filtrate containing the N-substituted cyclic imide.
    Type: Grant
    Filed: February 6, 1996
    Date of Patent: June 30, 1998
    Assignee: Bayer Aktiengesellschaft
    Inventors: Torsten Groth, Karl-Erwin Piejko, Winfried Joentgen, Josef Kasbauer, Bernd Alig, Werner Struver
  • Patent number: 5762951
    Abstract: The present invention relates to an acidic effervescent component for direct tableting of effervescent tablets and a process for its preparation.
    Type: Grant
    Filed: July 26, 1993
    Date of Patent: June 9, 1998
    Assignee: Bayer Aktiengesellschaft
    Inventors: Joachim Maasz, Christian Fritsch, Werner Grawingholt, Bernhard Streuff, Georg Frank
  • Patent number: 5728297
    Abstract: An apparatus for the mechanical cleaning of liquids, especially cooling water delivered from a heat exchanger and flowing in a pipeline (10), with a rotationally symmetrical, conical sieve (12) of substantially the size of the pipe diameter, as well as a coaxial suction device (20) which is disposed on the upstream side of the sieve, is mounted for rotation continuously or with interruptions for the duration of a cleaning interval, and during the cleaning interval sucks bit by bit the entire surface of the sieve (12) on the upstream side, the sieve (12) being divided into areas, the intake nozzle (22) of the suction device (20) can cover each area, and in each area of the actual sieve surface and of the suction device there is a cavity for the temporary accommodation of contaminants, the sieve (12) being divided on its upstream side by substantially radial barriers (36) into individual sectors forming the areas, the intake nozzle (22) of the suction device (20) has such a shape that, at the moment in which th
    Type: Grant
    Filed: January 30, 1996
    Date of Patent: March 17, 1998
    Inventor: Josef Koller
  • Patent number: 5712086
    Abstract: A process is presented for transfusing cells which have been sterilized with radiation and a quencher of type I and type II photodynamic reactions. The cells are removed from a donor and exposed to virucidally effective amount of radiation in the presence of a quencher of type I and type II reactions, or a mixture of a quencher for type I reactions and a quencher of type II reactions. Subsequently, the sterilized cell containing fraction is returned to the donor.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 27, 1998
    Assignee: New York Blood Center, Inc.
    Inventors: Bernard Horowitz, Bolanle Williams, Henrietta Margolis-Nunno, Sing N. Chin
  • Patent number: 5696170
    Abstract: Described is the use of microbicidal phenolic compounds in combination with glutaraldehyde for the preparation of disinfectants which are suitable for the disinfection of surfaces and instruments, but also of parts of the body, in hospitals and doctors' surgeries.
    Type: Grant
    Filed: November 21, 1995
    Date of Patent: December 9, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Otto Exner, Manfred Hoffmann
  • Patent number: 5695149
    Abstract: Carrier-roller winder having at least two winding stations, in which in the first winding station, a web is wound onto a core, whilst a second winding station is connected upstream from the first such that, at least at the moment the strip is cut, this is led over a cutting and guide roller (1') of the second station, the cutting and guide roller (1') being configured as a suction roller, such that, once the cut is completed, on the one hand the web end is wound over a cutting and guide roller (1) of the first winding station, which is likewise designed as a suction roller, and on the other hand the web beginning is led from the cutting and guide roller (1') of the second station to its wind-up zone, whereupon the first winding station is removed from its position and the second winding station is brought, as it continues winding, into the position of the first winding station, and an empty winding station, which is prepared for winding and which can also once again be the first emptied winding station, is br
    Type: Grant
    Filed: December 2, 1994
    Date of Patent: December 9, 1997
    Assignee: Beiersdorf Aktiengesellschaft
    Inventors: Reiner Schulze, Gunter Aster, Hans-Jurgen Bradersen
  • Patent number: 5695784
    Abstract: The invention relates to flavour-masked pharmaceutical compositions for oral administration, their preparation and their use as medicaments.The new pharmaceutical preparations according to the invention make it possible to administer pharmaceutical active substances having very unpleasant organoleptic properties such as, for example, very bad taste, even in liquid form.
    Type: Grant
    Filed: February 4, 1994
    Date of Patent: December 9, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Norbert Pollinger, Johannes Michaelis, Klaus Benke, Roland Rupp, Manfred Bucheler
  • Patent number: 5693451
    Abstract: The present invention relates to a single or multi-layer recording material for recording images or data, which material has at least one layer sensitive to light or to heat of a plastic containing a pyrrole compound or a pyrrole oligomer.
    Type: Grant
    Filed: September 23, 1994
    Date of Patent: December 2, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Alexa Sommer, Udo Herrmann, Robert Bloodworth, Gunther Penners, Klaus Sommer
  • Patent number: 5688963
    Abstract: The invention relates to a new process and to new intermediates for the preparation of triazolinones, most of which are known, of the general formula (I) ##STR1## in which R.sup.1 and R.sup.2 have the meanings given in the application, and which can be used as intermediates for the preparation of herbicides and insecticides.
    Type: Grant
    Filed: January 16, 1996
    Date of Patent: November 18, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wilhelm Haas, Karl-Heinz Linker, Kurt Findeisen
  • Patent number: 5684163
    Abstract: A process for the preparation of a N-)ortho-alkylphenyl)-imide of the formula ##STR1## in which R.sup.1 to R.sup.9 is defined in the specification which comprises reacting a cyclic anhydride of the formula ##STR2## wherein R.sup.6 to R.sup.9 are difined in the specification with an amine of the formula ##STR3## optionally in the presence of an acid catalyst and optionally in the presence of a solvent which is immiscible or only slightly miscible with water but can form an azeotrope with water, at a temperature between 100.degree. to 200.degree. C. under conditions so that the water formed during the reaction is removed from the reaction mixture without the addition of a polymerization inhibitor or a dipolar solvent. The final products are used as intermediates to prepare heat-stable plastics as well as intermediates to prepare pharmaceutical and agricultural chemicals.
    Type: Grant
    Filed: February 5, 1996
    Date of Patent: November 4, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Torsten Groth, Bernd-Michael Konig, Josef Kasbauer, Michael Schwamborn
  • Patent number: 5683741
    Abstract: Method for the quality-controlled treatment of surfaces with a radiation-cured surface treatment, in which a finishing formulation is applied to the surface and is polymerically crosslinked under the effect of radiation. To enable the quality control to be conducted non-destructively and at reduced cost, it is proposed that the finishing formulation contains a proton-affinitive indicator substance analyzable by ion mobility spectroscopy and that the indicator substance escaping from the printed or coated surface after the radiation curing is analyzed by means of ion mobility spectroscopy.
    Type: Grant
    Filed: May 17, 1995
    Date of Patent: November 4, 1997
    Assignees: Druckfarbenfabrik Gebr.Schmidt GmbH, Brucker-Saxonia Analytik GmbH
    Inventors: Hans-Peter Seng, Reiner Mehnert, Hans-Rudiger Doring
  • Patent number: 5682193
    Abstract: A latent image printing method and apparatus uses a substrate with one main surface having a covering comprising one of a first pair of a color developer and color former dye defining a background color in conjunction with the one main surface, wherein the color developer and the color former dye react when mixed to produce a first spectral response which is visible relative to the background color and a continuous coating over the covering which is non-porous with respect to the other of the pair and solvent-resistant to the other of the pair. The coating above selected portions of the covering corresponding to a desired latent image is removed.
    Type: Grant
    Filed: May 23, 1996
    Date of Patent: October 28, 1997
    Assignee: Nocopi Technologies, Inc.
    Inventor: Arshavir Gundjian
  • Patent number: D385480
    Type: Grant
    Filed: July 3, 1996
    Date of Patent: October 28, 1997
    Inventor: Stephen I. Mayo
  • Patent number: RE35768
    Abstract: To prepare storage-stable, low-dusting dyestuff granules which are readily soluble in plastics, a suspension of the dyestuff containing 0.1-5% by weight of a polyglycol are dried while being granulated.
    Type: Grant
    Filed: May 25, 1995
    Date of Patent: April 14, 1998
    Assignee: Bayer Aktiengesellschaft
    Inventors: Vaclav Kaspar, Horst Brandt, Gottfried Popp