Patents Represented by Attorney, Agent or Law Firm Sprung Kramer Schaefer & Briscoe
  • Patent number: 5984532
    Abstract: An optical fiber connector comprising a base and a lid member constituting an element having a doubly split structure which forms a roughly rod-like shape when united, and a spring for housing the base and lid member and applying pressure for pressing them together, wherein centering grooves for positioning and centering optical fibers for adjoinment and connection are provided in at least one or between the opposing faces of the base and lid member which are put together. In a mode wherein the element is inserted into a C-shaped spring having a rod shape with a C-shaped cross section, the optical fibers which are inserted from both ends of the element are pushed to the centering groove and adjoined into connection. By inserting or withdrawing wedges into wedge insertion grooves formed between the base and the lid member, it is possible to open or close the element.
    Type: Grant
    Filed: February 12, 1998
    Date of Patent: November 16, 1999
    Assignee: Fujikura Ltd.
    Inventors: Yasuhiro Tamaki, Toshiyuki Tanaka, Akito Nishimura, Yuichi Yoshida, Hiroshi Yokosuka
  • Patent number: 5985647
    Abstract: A stilbene synthase gene. More particularly, a stilbene synthase gene in which the stilbene synthase is resveratrol synthase. Also more particularly a stilbene synthase gene which is obtained from groundnut (Arachis hypogaea). Furthermore a stilbene synthase gene, corresponding to the stilbene synthase gene which is contained in the plasmid pGS 828.1, and DNA sequences acting in essentially the same say. Still further, a stilbene synthase gene unit which comprises approximately 6,700 base pairs and exhibits 3 EcoRI, 3 HindIII and 1 PstI cleavage sites, and which can be obtained by partial cleavage of the plasmid PGS 828.1 using EcoRI and HindIII, or from plasmid pGS 828.1 using SstI and PvuII.
    Type: Grant
    Filed: October 19, 1992
    Date of Patent: November 16, 1999
    Assignee: Bayer Aktiengesellschaft
    Inventors: Gudrun Schroder, Joachim Schroder, Rudiger Hain, Peter Helmut Schreier
  • Patent number: 5986105
    Abstract: The invention relates to new quinolone- and naphthyridonecarboxylic acid derivatives which are substituted in the 7-position by a tricyclic amine radical, their salts, processes for their preparation and antibacterial compositions comprising these compounds.
    Type: Grant
    Filed: November 20, 1998
    Date of Patent: November 16, 1999
    Assignee: Bayer Aktiengesellschaft
    Inventors: Uwe Petersen, Thomas Schenke, Thomas Jaetsch, Stephan Bartel, Klaus Dieter Bremm, Rainer Endermann, Karl Georg Metzger
  • Patent number: 5985332
    Abstract: Artificial oxygen carrier composed of native or modified hemoglobins for direct biological or medical use, in which the oxygen binding site of the hemoglobin is provided with a protective ligand, preferably carbon monoxide, which does not have to be removed prior to use.
    Type: Grant
    Filed: January 9, 1998
    Date of Patent: November 16, 1999
    Assignee: Sanguibiotech AG
    Inventors: Wolfgang Barnikol, Harald Potzschke
  • Patent number: 5981438
    Abstract: The present invention relates to novel 1-Phenyl-5-anilinotetrazoles of the formula (I): ##STR1## wherein, R.sup.1, R.sup.2, R.sup.3, R.sup.4, m and n have the meaning provided in the specification, precesses for their preparation and their use as microbiocides, insecticides and/or herbicides.
    Type: Grant
    Filed: January 22, 1998
    Date of Patent: November 9, 1999
    Assignee: Nihon Bayer Agrochem K.K.
    Inventors: Fritz Maurer, Kaori Kido, Yoshio Kurahashi, Haruko Sawada, Keiko Tanaka, Yuichi Otsu, Yumi Hattori, Katsuhiko Shibuya, Takahisa Abe, Toshio Goto, Seishi Ito
  • Patent number: 5981566
    Abstract: The present invention relates to new acylated 5-aminopyrazoles of the formula (I) ##STR1## in which R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 have the meaning given in the description, to processes for their preparation and to their use as pesticides.
    Type: Grant
    Filed: September 2, 1998
    Date of Patent: November 9, 1999
    Assignee: Bayer Aktiengesellschaft
    Inventors: Konrad Wernthaler, Markus Heil, Christoph Erdelen
  • Patent number: 5981208
    Abstract: A method useful in the diagnosis of Alzheimer's Disease in a patient in which an amyloid protein precursor (APP) substrate is combined with a sample of cerebrospinal fluid or blood obtained from the patient to be tested, and poteolytic cleavage of the APP substrate is detected. The absence of detectable proteolytic cleavage, or the detection of a substantially lesser degree of proteolytic cleavage, in the presence of the patient's sample compared to that detected when an APP substrate is combined with test samples from control individuals, indicates affliction with Alzheimer's Disease. Convenient test reagents and kits for aiding the diagnosis of Alzheimer's Disease are provided, such as comprising an APP substrate and immunoreagents for detecting a fragment formed by proteolytic cleavage as well as chromogenic APP substrates.
    Type: Grant
    Filed: October 6, 1994
    Date of Patent: November 9, 1999
    Assignee: Bayer Corporation
    Inventors: Paul P. Tamburini, Robert N. Dreyer, Kathryn M. Bausch
  • Patent number: 5980970
    Abstract: The invention relates to W/O lotions having a content of at least one unsaturated fatty acid derivative, which are characterized in that they comprise W/O emulsifiers, W/O stabilizers and/or W/O emulsion systems chosen from the group consisting of(A) a W/O emulsifier based on ethoxylated castor oil,(B) a W/O emulsifier (B1) based on sorbitan isostearate and a W/O stabilizer (B2) based on a polyalkylene glycol copolymer and(C) a W/O emulsion system based on a methoxy-polyalkylene glycol copolymer, either(1) the W/O emulsifier of (A) being used, or(2) the W/O emulsifier (B1) being used together with the W/O stabilizer B2 (B), or(3) a combination comprising emulsifiers (A) and (B) with (B1) and (B2) being used, where, in each case,(4) the emulsion system (C) can also be used together with (1) or (2) or (3), and water and, if appropriate, additives or auxiliaries.
    Type: Grant
    Filed: September 25, 1997
    Date of Patent: November 9, 1999
    Assignee: Beiersdorf AG
    Inventors: Henning Sattler, Dagmar Zelle
  • Patent number: 5981567
    Abstract: The invention concerns substituted spiroheterocyclic 1H-3-arylpyrrolidine-2,4-dione derivatives of formula (I) in which A and B together with the carbon atom to which they are bound, are an unsubstituted or substituted 5- or 6-membered ring including at least one hetero atom; X is alkyl, halogen or alkoxy; Y is hydrogen, alkyl, halogen, alkoxy or alkyl halide; Z is alkyl, halogen or alkoxy; n is 0, 1, 2 or 3; G is hydrogen (a) or one of the groups (b), (c), (d), (e), (f) or (g), E is a metal-ion equivalent or an ammonium ion; L and M are each oxygen or sulphur and R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 are as defined in the description. The invention also concerns methods of preparing such compounds as well as intermediates of formula (XVII) and (II) in which A, B, X, Y, Z and n are as defined in claim 1 and R.sup.8 is alkyl. Compounds of formula (I) are suitable for use as pest-control agents.
    Type: Grant
    Filed: December 28, 1995
    Date of Patent: November 9, 1999
    Assignee: Bayer Aktiengesellschaft
    Inventors: Reiner Fischer, Thomas Bretschneider, Bernd-Wieland Kruger, Hans-Joachim Santel, Markus Dollinger, Christoph Erdelen, Ulrike Wachendorff-Neumann
  • Patent number: 5981700
    Abstract: Pancreatic islet cell antigens (ICA) that bind with antibodies found in the sera of patients afflicted with insulin-dependent (Type I) diabetes mellitus (IDDM). ICA proteins are expressed by recombinant cloning vehicles comprising DNA inserts isolated from islet cells. Full sequence native ICA proteins, or protein or peptide fragments thereof, can be used in the diagnosis of IDDM and in detecting or blocking human immunoglobulin, T-cells, or B-cells involved in IDDM.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: November 9, 1999
    Assignee: Bayer Corporation Formerly Molecular Diagnostics, Inc.
    Inventor: Daniel U. Rabin
  • Patent number: 5981436
    Abstract: The invention relates to new substituted diazacyclohexanedi(thi)ones of the general formula (I) ##STR1## in which Q.sup.1, Q.sup.2, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 have the meanings given in the description,a process for their preparation, new intermediate products and their use as herbicides.
    Type: Grant
    Filed: April 29, 1998
    Date of Patent: November 9, 1999
    Assignee: Bayer Aktiengesellschaft
    Inventors: Mark-Wilhelm Drewes, Roland Andree, Otto Schallner, Hans-Joachim Santel, Markus Dollinger
  • Patent number: 5976863
    Abstract: Ferulic acid, vanillic acid, coniferyl alcohol and coniferyl aldehyde can be prepared from eugenol with the aid of a new Pseudomonas species.
    Type: Grant
    Filed: January 24, 1996
    Date of Patent: November 2, 1999
    Assignee: Haarmann & Reimer GmbH
    Inventors: Rudolf Hopp, Jurgen Rabenhorst
  • Patent number: 5977279
    Abstract: An organopolysiloxane composition that can be crosslinked by addition, comprisinga) a branched organopolysiloxane having unsaturated hydrocarbon groups, and triorganosiloxy end unitswherein at least 90% of the organo groups are methyl groups,the number average molecular weight of which is on average from 9,000 to 60,000,wherein the ratio of the number of diorganosiloxy units (D-units) to the number of branch points is on average between 15 and 40, andwherein at least one triorganosiloxy unit (M-unit) and at maximum half of all the M-units are free of unsaturated radicals, the remaining M-units each have only one unsaturated radical and the content of unsaturated radicals is from 0.
    Type: Grant
    Filed: August 19, 1994
    Date of Patent: November 2, 1999
    Assignee: GE Bayer Silicones GmbH & Co. KG
    Inventors: Armand de Montigny, Hans-Horst Steinbach, Udo Herrmann
  • Patent number: 5977401
    Abstract: The present invention relates to a novel intermediate compound for preparing optionally substituted 1,2,4-triazolinones and a process for preparing that intermediate compound.
    Type: Grant
    Filed: April 14, 1999
    Date of Patent: November 2, 1999
    Assignee: Bayeraktiengesellschaft
    Inventor: Heinz-Jurgen Wroblowsky
  • Patent number: 5977123
    Abstract: The invention relates to novel oximether and acrylic acid derivatives of the formula (I) ##STR1## in which Z, G, Ar, E, R.sup.1 and R.sup.2 have the meanings as given in the specification, to processes for their preparation and to their use as fungicides.
    Type: Grant
    Filed: January 9, 1998
    Date of Patent: November 2, 1999
    Assignee: Bayer Aktiengesellscgaft
    Inventors: Peter Gerdes, Herbert Gayer, Ulrich Heinemann, Ralf Tiemann, Klaus Stenzel, Stefan Dutzmann
  • Patent number: 5977419
    Abstract: The invention relates to novel processes for the preparation of phenyl acetic acid derivatives of the formula (I) some of which are known ##STR1## in which R.sup.1, R.sup.2 and R.sup.3 independently of each other each represent hydrogen, alkyl or alkoxy by ozonolysis of compounds of the formula (II) ##STR2## in which R.sup.4 represents hydrogen or methyl and oxidation of the reaction products obtained therefrom. The invention further relates to novel intermediates and a process for the preparation thereof.
    Type: Grant
    Filed: December 22, 1997
    Date of Patent: November 2, 1999
    Assignee: Bayer Aktiengesellschaft
    Inventors: Reinhard Lantzsch, Rainer Fuchs
  • Patent number: 5977029
    Abstract: The invention relates to novel 3-aryl-5-halogeno-pyrone derivatives of the formula (I) ##STR1## in which A, D, G, X, Y, Z and n are each as defined in the description,to a plurality of processes and intermediates for their preparation and to their use as pesticides and herbicides.
    Type: Grant
    Filed: April 20, 1998
    Date of Patent: November 2, 1999
    Assignee: Bayer Aktiengesellschaft
    Inventors: Reiner Fischer, Folker Lieb, Michael Ruther, Jorg Stetter, Markus Dollinger, Christoph Erdelen, Norbert Mencke, Hans-Joachim Santel, Andreas Turberg, Ulrike Wachendorff-Neumann
  • Patent number: 5977362
    Abstract: Quinazoline-2,4-diones are obtained in high yields and purities by reacting anthranilic acids with isocyanates and then, without isolation of the urea formed as intermediate, treating the reaction mixture with acid.
    Type: Grant
    Filed: May 26, 1998
    Date of Patent: November 2, 1999
    Assignee: Bayer Aktiengesellschaft
    Inventors: Nikolaus Muller, Klaus-Christian Paetz, Wolfgang Kiel
  • Patent number: 5972844
    Abstract: The invention relates to sulphonylamino(thio)carbonyl-triazolin(ethi)ones of the general formula (I) ##STR1## in which Q.sup.1 represents oxygen or sulphur,Q.sup.2 represents oxygen or sulphur,R.sup.1 represents hydrogen, hydroxyl, amino, alkylideneamino or a respectively optionally substituted radical from the group consisting of alkyl, alkenyl, alkinyl, alkoxy, alkenyloxy, alkylamino, dialkylamino, alkanoylamino, cycloalkyl, cycloalkylamino, cycloalkylalkyl, aryl and arylalkyl,R.sup.
    Type: Grant
    Filed: July 18, 1997
    Date of Patent: October 26, 1999
    Assignee: Bayer Aktiengesellschaft
    Inventors: Klaus-Helmut Muller, Joachim Kluth, Ernst Rudolf F Gesing, Klaus Konig, Markus Dollinger, Hans-Joachim Santel
  • Patent number: 5972843
    Abstract: The present invention relates to novel acylated 5-aminoisothiazoles of the formula (I) ##STR1## in which R.sup.1, R.sup.2, R.sup.3, R.sup.4 and Y have the meaning given in the description, processes for their preparation and their use for controlling animal pests.
    Type: Grant
    Filed: May 11, 1998
    Date of Patent: October 26, 1999
    Assignee: Bayer Aktiengesellschaft
    Inventors: Markus Heil, Christoph Erdelen, Ulrike Wachendorff-Neumann, Andreas Turberg, Norbert Mencke