Patents Represented by Attorney, Agent or Law Firm Steven J. Hultquist
  • Patent number: 6584935
    Abstract: The present invention relates to a recirculating marine aquaculture process for production of a crab species, including (i) a broodstock conditioning, (ii) spawning, (iii) egg incubation, (iv) larval growth, (v) nursery post-larval growth, and (vi) grow-out of the crab to a final product weight, in which each stage (i)-(vi) of the process involves operation in an aqueous medium that is coupled in liquid recirculation relationship with waste component removal from the aqueous medium and returning purified aqueous medium to the external environment. The process involves operation in a closed, recirculating aquaculture system in which photoperiod, water temperature, water chemistry, and diet are optimized and then continuously monitored and controlled to obtain optimal production at each of the six phases (i)-(vi) of the life cycle.
    Type: Grant
    Filed: August 19, 2002
    Date of Patent: July 1, 2003
    Assignee: University of Maryland Biotechnology Institute
    Inventors: Yonathan Zohar, Oded Zmora, Anson Hines
  • Patent number: 6581623
    Abstract: An auto-switching sub-atmospheric pressure gas delivery system, for dispensing gas to a gas-consuming process unit, e.g., a semiconductor manufacturing tool, without the occurrence of pressure spikes or flow perturbations.
    Type: Grant
    Filed: May 1, 2000
    Date of Patent: June 24, 2003
    Assignee: Advanced Technology Materials, Inc.
    Inventors: Kent Carpenter, James Dietz
  • Patent number: 6583445
    Abstract: An integrated electronic-optoelectronic module comprising: an ultrathin silicon-on-sapphire composite substrate; at least one electronic device fabricated in the ultrathin silicon; and at least one optoelectronic device bonded to the ultrathin silicon-on-sapphire composite substrate and in electrical communication with the at least one electronic device fabricated in the ultrathin silicon layer. For example, VCSELs and photodetectors are integrated with CMOS electronic circuitry to provide useful modules for electro-optical interconnects for computing and switching systems.
    Type: Grant
    Filed: September 8, 2000
    Date of Patent: June 24, 2003
    Assignees: Peregrine Semiconductor Corporation, George Mason University, John Hopkins University, The United States of America as represented by the Secretary of the Army
    Inventors: Ronald E. Reedy, Ravindra A. Athale, George J. Simonis, Andreas G. Andreou, Alyssa Apsel, Zaven Kalayjian, Philippe O. Pouliquen
  • Patent number: 6579703
    Abstract: Small heat shock proteins, e.g., Pyrococcus fuiosus (Pfu-sHSP), confer thermotolerance on cellular cultures and on proteins in cellular extracts during prolonged incubation at elevated temperature, demonstrating the ability to protect cellular proteins and maintain cellular viability under heat stress conditions. Such heat shock proteins are effective to combat enzymatic aggregation and intracellular precipitation during heat stress, and thereby enable enhancement of the utility and stability of enzymes in various applications, e.g., Taq polymerase in PCR applications, digestive enzymes in microbial degradative applications, etc.
    Type: Grant
    Filed: April 16, 2001
    Date of Patent: June 17, 2003
    Assignee: University of Maryland Biotechnology Institute
    Inventors: Frank T. Robb, Pongpan Laksanalamai
  • Patent number: 6576573
    Abstract: The present invention relates to a method and system for non-thermal abatement of effluent species generated in a semiconductor processing unit. In the method, an effluent stream is introduced into a discharge reactor wherein the components of the effluent stream are subjected to a corona discharge and maintained therein for a sufficient time to detoxify and/or dissociate the harmful components of the effluent stream. The discharge reactor, maintained at approximately atmospheric pressure, is positioned after the low-pressure semiconductor processing chamber and connecting vacuum pump system to limit interference with the semiconductor plasma processing tool.
    Type: Grant
    Filed: February 9, 2001
    Date of Patent: June 10, 2003
    Assignee: Advanced Technology Materials, Inc.
    Inventor: Jose I. Arno
  • Patent number: 6576708
    Abstract: A polypropylene composition and modified fibers thereof, includes polypropylene and an elastomer. The elastomer has a melting temperature of, at least, 80° C., preferably 100-180° C., a melt flow index in the range of 1-60 g/10-min., and a density within the range of 0.85-0.95 g/cm3. The elastomer is a branched copolymer of an ethylene copolymer, a polyolefin copolymer or a combination thereof, with ethylene, higher alkene groups, or both ethylene and higher alkene groups in the main chain of the branched copolymer, and with a weight proportion of polypropylene to elastomer being in the range of from 99.9:0.1 to 0.1:99.9. A method for producing the polypropylene composition and modified fibers thereof is also disclosed.
    Type: Grant
    Filed: April 18, 2000
    Date of Patent: June 10, 2003
    Assignee: Instytut Wlokien Chemicznych
    Inventors: Henryk Struszczyk, Karlina Grzebieniak, Alojzy Urbanowski, Arkadiusz Wilczek, Stanislaw Galecki, Jan Kazmierski, Konrad Kazmierski
  • Patent number: 6569418
    Abstract: The present invention relates to a composition and method for enhancing the efficacy of a vaccine in a subject treated with the vaccine by administering to the subject an antigen in conjunction with a chemokine.
    Type: Grant
    Filed: June 12, 2000
    Date of Patent: May 27, 2003
    Assignee: University of Maryland Biotechnology Institute
    Inventors: Alfredo Garzino-Demo, Anthony L. DeVico
  • Patent number: 6569340
    Abstract: A process and apparatus for purifying one or more target substances from a source liquid, employing one or more cross-flow filter elements, and one or more types of chromatography resins, in combination, to provide purification with advantageous yield, product purity, and cost- and time-efficiency.
    Type: Grant
    Filed: March 27, 2002
    Date of Patent: May 27, 2003
    Inventor: Henry B. Kopf
  • Patent number: 6559328
    Abstract: An indium precursor composition having utility for incorporation of indium in a microelectronic device structure, e.g., as an indium-containing film on a device substrate by bubbler or liquid delivery MOCVD techniques, or as a dopant species incorporated in a device substrate by ion implantation techniques. The precursor composition includes a precursor of the formula R1R2InL wherein: R1 and R2 may be same or different and are independently selected from C6-C10 aryl, C6-C10 fluoroaryl, C6-C10 perfluoroaryl, C1-C6 alkyl, C1-C6 fluoroalkyl, or C1-C6 perfluoroalkyl; and L is &bgr;-diketonato or carboxylate. Indium-containing metal films may be formed on a substrate, such as indium-copper metallization, and shallow junction indium ion-implanted structures may be formed in integrated circuitry, using the precursors of the invention.
    Type: Grant
    Filed: April 3, 2001
    Date of Patent: May 6, 2003
    Assignee: Advanced Technology Materials, Inc.
    Inventors: Thomas H. Baum, Chongying Xu
  • Patent number: 6554977
    Abstract: A method and apparatus for purifying aqueous effluent streams to reduce chemical oxygen demand thereof, where the method comprises direct oxidation of water-soluble organic material in an electrochemical cell that incorporates stainless steel electrodes, whose stability and lifetime are enhanced by inclusion of circulating metal chips.
    Type: Grant
    Filed: May 15, 2001
    Date of Patent: April 29, 2003
    Inventors: Clyde Kuen-Hua Hu, Paul Pei-Yung Hu, Patrick Pei-Chih Hu
  • Patent number: 6548287
    Abstract: The present invention provides gram-negative bacterial strains that produce substantially pure non-pyrogenic lipopolysaccharide or lipid A. The present invention also relates to a use of said strains for the preparation of non-pyrogenic DNA and use of the same for introducing endogenous or foreign genes into animal cells or animal tissue. Further, the present invention relates to a use of said strains for the preparation of non-pyrogenic recombinant mammalian, protozoan and viral proteins. Furthermore, the present invention relates to a use of said strains for the preparation of non-pyrogenic bacterial vaccines and vaccine vectors. Yet a further use of the present invention relates to a use of said strains for the preparation of non-pyrogenic bacterial proteins and polysaccharides antigens for use as vaccines.
    Type: Grant
    Filed: June 24, 1999
    Date of Patent: April 15, 2003
    Assignee: University of Maryland, Baltimore
    Inventors: Robert J. Powell, David M. Hone
  • Patent number: 6541208
    Abstract: The HIV-1 transactivator protein Tat significantly increases astrocytic expression and release of monocyte chemoattractant protein-1. Monocyte chemoattractant protein-1 (MCP-1) is expressed in the brains of patients with HIV-1-associated dementia, and is present in the cerebrospinal fluid of patients with this condition. This present invention employs compounds, such as MCP-1 antagonists and partial agonists, as well as HIV-1 Tat-inhibitors in methods for treating and/or preventing HIV-1 associated dementia.
    Type: Grant
    Filed: March 17, 1998
    Date of Patent: April 1, 2003
    Assignee: University of Maryland Biotechnology Institute
    Inventor: Alfredo Garzino-Demo
  • Patent number: 6541234
    Abstract: Novel calcium free subtilisin mutants are taught, in particular subtilisins which have been mutated to eliminate amino acids 75-83 and which retain enzymatic activity and stability. Recombinant methods for producing same and recombinant DNA encoding for such subtilisin mutants are also provided.
    Type: Grant
    Filed: September 11, 2000
    Date of Patent: April 1, 2003
    Assignee: University of Maryland Biotechnology Institute
    Inventor: Philip N. Bryan
  • Patent number: 6540814
    Abstract: An ion implantation process system, including an ion implanter apparatus for carrying out an ion implantation process. A supply of source gas for the ion implantation process is arranged to flow to the ion implanter apparatus, which discharges an effluent gas stream including ionization products of the source gas during the ion implantation process. The system includes an effluent abatement apparatus for removing hazardous effluent species from the effluent gas stream. The source gas may be furnished from a low pressure gas source in which the source gas is sorptively retained in a vessel on a sorbent medium having affinity for the source gas, and desorbed for dispensing to the process system. A novel scrubbing composition may be employed for effluent treatment, and the scrubbing composition breakthrough of scrubbable component may be monitored with a device such as a quartz microbalance monitor.
    Type: Grant
    Filed: November 29, 2001
    Date of Patent: April 1, 2003
    Assignee: Advanced Technology Materials, Inc
    Inventors: Michael W. Hayes, Mark R. Holst, Jose I. Arno, Glenn M. Tom
  • Patent number: 6540819
    Abstract: A gas supply system including a gas cabinet defining an enclosure including therein a gas dispensing manifold and one or more adsorbent-based gas storage and dispensing vessels mounted in the enclosure and joined in gas flow communication with the gas dispensing manifold. The enclosure may be maintained under low or negative pressure conditions for enhanced safety in the event of leakage of gas from the gas storage and dispensing vessel(s) in the enclosure. The gas supply system may be coupled to a gas-consuming unit in a semiconductor manufacturing facility, e.g., an ion implanter, an etch chamber, or a chemical vapor deposition reactor.
    Type: Grant
    Filed: December 5, 2001
    Date of Patent: April 1, 2003
    Assignee: Advanced Technology Materials, Inc.
    Inventors: Glenn M. Tom, James V. McManus
  • Patent number: 6541235
    Abstract: Novel calcium free subtilisin mutants are taught, in particular subtilisins which have been mutated to eliminate amino acids 75-83 and part or all of amino acids 1-22 (the N-terminal region) and which retain enzymatic activity and stability. Recombinant methods for producing the same and recombinant DNA encoding for such subtilisin mutants are also provided.
    Type: Grant
    Filed: September 29, 2000
    Date of Patent: April 1, 2003
    Assignee: University of Maryland Biotechnology Institute
    Inventor: Philip N. Bryan
  • Patent number: 6538183
    Abstract: Methods of construction for acoustic and electrically amplified stringed musical instruments. The invention further relates to acoustic and electrically amplified stringed musical instruments comprising fiber-reinforced resin composite materials, where the instruments are provided with a sound-damping interior coating.
    Type: Grant
    Filed: February 7, 2001
    Date of Patent: March 25, 2003
    Inventor: Frederick J. Verd
  • Patent number: 6537353
    Abstract: A method and apparatus for abatement of effluent from a CVD process using a source reagent having a metal organic loosely bound to a organic or organomettalic molecule such that upon exposure to heat such bond is readily cleavable, e.g., copper deposition process involving the formation of films on a substrate by metalorganic chemical vapor deposition (CVD) utilizing a precursor composition for such film formation. The abatement process in specific embodiments facilitates high efficiency abatement of effluents from copper deposition processes utilizing Cu(hfac)TMVS as a copper source reagent.
    Type: Grant
    Filed: April 6, 2001
    Date of Patent: March 25, 2003
    Assignee: Advanced Technology Materials, Inc.
    Inventors: Mark Holst, Ray Dubois, Jose Arno, Rebecca Faller, Glenn Tom
  • Patent number: 6533874
    Abstract: A method of forming a (gallium, aluminum, indium) nitride base layer on a substrate for subsequent fabrication, e.g., by MOCVD or MBE, of a microelectronic device structure thereon. Vapor-phase (Ga, Al, In) chloride is reacted with a vapor-phase nitrogenous compound in the presence of the substrate, to form (Ga, Al, In) nitride. The (Ga, Al, In) nitride base layer is grown on the substrate by HVPE, to yield a microelectronic device base comprising a substrate with the (Ga, Al, In) nitride base layer thereon. The product of such HVPE process comprises a device quality, single crystal crack-free base layer of (Ga, Al, In) N on the substrate, in which the thickness of the base layer may, for example, be on the order of 2 microns and greater and the defect density of the base layer may, for example, be on the order of 1E8 cm−2 or lower. Microelectronic devices thereby may be formed on the base layer, over a substrate of a foreign (poor lattice match) material, such as sapphire.
    Type: Grant
    Filed: September 7, 2000
    Date of Patent: March 18, 2003
    Assignee: Advanced Technology Materials, Inc.
    Inventors: Robert P. Vaudo, Joan M. Redwing, Michael A. Tischler, Duncan W. Brown, Jeffrey S. Flynn
  • Patent number: 6532844
    Abstract: For a crankshaft of a motor with two outputs, which are braced against each other on a common shaft section by means of an essentially axial directed bracing force, measures are suggested, which deflect the axially directed bracing force into a bracing force with a radial component, that acts on at least one output.
    Type: Grant
    Filed: July 16, 2002
    Date of Patent: March 18, 2003
    Assignee: Gif Geselleschaft for Indusrie Forschung mbH
    Inventor: Ulrich Rohs