Abstract: Systems, methods, and machine-readable media are disclosed to provide notification of receipt of a communication across multiple platforms of potential diverse types. Cross-platform message notification can comprise receiving a request to initiate a communication from an initiating end device. The request may identify a single intended recipient device. A plurality of possible recipient devices can be identified for the request to initiate a communication based on user profile information from a user of the initiating end device. The request to initiate a communication can be forwarded to each of the plurality of possible recipient devices at substantially a same time. The initiating end device can be connected to one of the plurality of possible recipient devices based on a response from at least one of the possible recipient devices.

Abstract: Methods, compositions and kits are provided for measuring aspirin's anti-thrombotic effectiveness on a subject. Included are a novel assay for quickly and specifically measuring TxA2 metabolite levels in urine and correlating the levels with aspirin dose in a subject. The methods, compositions and kits utilize a novel anti TxA2 metabolite antibody.

Abstract: The present invention relates to a microorganism producing inosine, which is one of purine nucleoside, an important material for 5?-inosinic acid synthesis, and method for producing inosine using the same. More particularly, the present invention relates to a recombinant microorganism of Corynebacterium genus producing inosine at high concentration by inactivating the gene encoding nucleoside hydrolase II and by enhancing the expression of the gene encoding 5?-nucleotidase, which still retains the characteristics of Corynebacterium ammoniagenes CJIP2401 (KCCM-10610).

Abstract: A herpes simplex virus is disclosed in which the herpes simplex virus genome comprises a nucleic acid sequence encoding an ING4 polypeptide.

Abstract: A nanoporous polymer electrolyte and methods for making the polymer electrolyte are disclosed. The polymer electrolyte comprises a crosslinked self-assembly of a polymerizable salt surfactant, wherein the crosslinked self-assembly includes nanopores and wherein the crosslinked self-assembly has a conductivity of at least 1.0×10?6 S/cm at 25° C. The method of making a polymer electrolyte comprises providing a polymerizable salt surfactant. The method further comprises crosslinking the polymerizable salt surfactant to form a nanoporous polymer electrolyte.

Abstract: An eye surgical instrument, comprising at least one optical fiber for lighting of the interior of the eye, which at least one optical fiber, at a free end thereof, is provided with a light exit and with a stop situated at a distance from the free end, which stop defines an insertion part situated between the end and the stop, and at an other end is connectable to a light source, while the stop forms a separate element which is arranged so as to be slidable along the at least one fiber.

Abstract: A medicament dispensing device including a substantially rigid carpule body which has a dispensing end and an actuation end opposite the dispensing end. The carpule body is substantially tubular and thus defines a carpule bore. The device further includes a plunger operatively disposed within the carpule bore having a plunger actuator near the actuation end of the carpule body and a plunger tip opposite the plunger actuator. The plunger tip and an orifice at the dispensing end of the carpule bore define a medicament volume which may be loaded with a medicament selected to achieve specific therapeutic goals. The carpule body may also include a wound depth scale. The depth scale is typically associated with the dispensing end of the carpule body. Similarly, the medicament dispensing device may include a dosage scale. Also disclosed are methods of dispensing medicaments.

Abstract: The invention relates to a coated article which has (i) at least one electrically non-conducting base layer, (ii) at least one layer of copper and/or a copper alloy, and (iii) a layer which contains at least one electrically conductive polymer, wherein the copper or copper alloy layer (ii) is positioned between the base layer (i) and the layer containing the conductive polymer (iii), and which is characterized in that the layer (iii) contains at least one precious metal or at least one semiprecious metal or a mixture thereof. The invention also relates to a process for its production and also its use for the prevention of corrosion and to preserve the solderability of printed circuit boards.

Abstract: The present invention provides novel amide and sulfonamide substituted heterocyclic urea compounds having useful antibacterial activity. Use of these compounds as pharmaceutical compositions and method of their production are also provided.

Abstract: Novel tools and techniques for providing video calling solutions. In some such solutions, a video calling device resides functionally inline between a set-top box and a television set. Such solutions can provide, in some cases, high performance video calling, high video quality, simplified installation, configuration and/or use, and/or the ability to enjoy video calling in an inclusive, comfortable environment, such as a family room, den, or media room.

Abstract: The invention relates to a processing unit of a measuring signal related to conditions of an object controlled by power electronics. The processing unit comprises an interface with digital terminals, wherein the interface is provided with at least one terminal for a sensor which generates the measuring signal. Further, the processing unit comprises a calculating unit to which the interface is connected. The calculating unit is equipped with a real-time control system. In addition, the calculating unit comprises a general-purpose processor.

Abstract: A synergistically effective combination of an anti-cancer agent and a therapeutic compound, such as an mTOR-Rictor complex inhibitor, a Serine 473 phosphorylation inhibitor, an AKT2 inhibitor, or a combination thereof, for use in the treatment of cancer, and methods and uses thereof. Also included are methods and uses of a thiosemicarbazone for treating a cancer in a mammal in need thereof characterized by over-expression of RAS, by an EGFR mutation, and/or by over-expression of AKT2.

Abstract: The present invention provides, in part, a dexterous endoscope apparatus, referred to herein as a MicroFlex Scope (MFS). The MFS is an novel, small diameter, e.g., less about 1 mm to about 4 mm, about 1 mm to about 3 mm, etc., dexterous endoscope that allows for access, direct visualization, tissue sampling, treatment, etc. of body lumens. In one embodiment, the distal end of the MFS of the invention is an ultra-flexible tip that comprises a plurality of thin, curved shape memory alloy (SMA) actuator elements attached to at least one structural skeleton, e.g., a coil spring skeleton or hinge structure. The SMA actuator elements in each structural skeleton segment are indirectly heated by a heater element and produce force in response to their temperature relative to specific thresholds. In certain embodiments, the heater element may include an integrated heater/sensor element adapted to heat the actuator element and to sense the temperature and bend state of the actuator element.

Abstract: This invention relates to the field of therapeutic agents for the treatment of Age-Associated Memory Impairment (AAMI). In particular, the present invention utilizes compositions comprising at least one compound capable of elevating ketone body concentrations in a mammal (e.g., ketogenic compounds), administered in an amount effective for treatment or prevention of loss of cognitive function caused by reduced neuronal metabolism in AAMI. In one embodiment, the composition includes medium chain triglycerides (MCT). In another embodiment, the compositions are administered in the presence of carbohydrate. The present invention also relates to oral dosage forms, in particular, a nutritional drink comprising at least one compound capable of elevating ketone body concentrations in a mammal.

Abstract: A hybrid parachute, method of deploying a parachute and method of landing a payload. The hybrid parachute utilizes a reefing system that provides for the initial deployment of a deceleration stage that is configured to withstand the stresses of high-speed and/or high altitude openings. The deceleration stage has operating characteristics similar to known high-speed parachutes. After sufficient deceleration has been achieved with the deceleration stage, reefings are released deploying one or more low-speed high drag stages of the device. The high drag stage(s) provide the landing characteristics of a low-speed parachute, including the possibility of controlled descent and landing.

Abstract: Provided is a method of stabilizing and solidifying elemental mercury using sulfur and paraffin. The method includes reacting elemental mercury with sulfur to prepare a mercury sulfide compound, adding a mixture of the mercury sulfide compound and the remaining sulfur after the reaction to high-temperature liquid paraffin to melt the remaining sulfur, and cooling the sulfur to solidify the mercury sulfide compound. According to the method of stabilizing and solidifying elemental mercury using sulfur and paraffin, a surface of a solidified product is covered with a thin paraffin layer to prevent exposure to the outside.

Abstract: The invention relates to a device for recovering moisture present in the atmosphere. The device comprises a collection structure with a water recovery surface which during use at least partly makes an angle with respect to the orientation of gravity. Further, the collection structure is detachably couplable to a reservoir for storing the recovered moisture. In addition, the collection structure is nestable.

Abstract: An apparatus for heat exchange with radial mixing comprises a trough with two rotatably arranged shafts extending alongside each other, which shafts are each provided with paddles spaced apart in an axial direction with an intermediate distance. The paddles extend substantially in a radial plane with respect to the shafts, and extend in a circumferential direction over at least a part of the circumference. In the circumferential direction, the paddles are at least partly wedge-shaped. Upon opposite rotation of the shafts, successive paddles mesh alternately, thereby forming a gap narrowing again and again. Per shaft, successive paddles in an axial direction are staggered relative to each other in circumferential direction through an angle.