Abstract: Computer systems and methods of data processing are disclosed in which hierarchical descriptors define levels of fault/event management to intelligently monitor hardware and software and proactively take action in accordance with a defined fault policy. A fault policy based on a defined hierarchy ensures that for each particular type of failure the most appropriate action is taken. Hierarchical descriptors can be used to provide information specific to each failure or event. The hierarchical descriptors provide granularity with which to report faults, take action based on fault history and apply fault recovery policies. The descriptors can be stored in a master event log file or local event log files through which faults and events may be tracked and displayed to the user and allow for fault detection at a fine granular level and proactive response to events. In addition, the descriptors can be matched with descriptors in a fault policy to determine the recovery action to be taken.

Abstract: A purified mammalian proteoglycan, and genetic information encoding such proteoglycans, having a core polypetide molecular weight of about 30 kD to about 35 kD, and comprising a hydrophilic amino terminal extracellular region, a hydrophilic carboxy terminal cytoplasmic region, a transmembrane hydrophobic region between said cytoplasmic and extracellular regions, a protease susceptible cleavage sequence extracellularly adjacent the transmembrane region of the peptide, and at least one glycosylation site for attachment of a heparan sulfate chain to said extracellular region, said glycosylation site comprising a heparan sulfate attachment sequence represented by a formula Xac-Z-Ser-Gly-Ser-Gly (SEQ ID NO: 44), where Xac represents an amino acid residue having an acidic sidechain, and Z represents from 1 to 10 amino acid residues. Additional peptides having this glycosylation site and genetic information useful for preparing a number of variations based on this glycosylation site are also provided.

Abstract: The present invention provides methods and systems for generating ultrasound images of a plurality of scatterers disposed in a target region. More particularly, a method of the invention derives model response functions for each of a plurality of transducers for a given distribution of scattering media. The interrogation pattern can be selected to include a set of unfocused ultrasound waves generated by one or more of the transducers. The interrogation pattern is transmitted into the target region, and the transducers are utilized to detect echoes generated by the scatterers in the target region in response to the interrogation pattern. The methods and systems of the invention advantageously allow obtaining ultrasound images of a target region without employing beamforming either in transmission of ultrasound waves into the region or in detection of echoes generated by scatterers in the target region in response to the transmitted waves.

Abstract: A distributed software redundancy design is disclosed to minimize network outages and other problems associated with component/process failures by spreading software backup (in the so-called “hot state”) across multiple elements. The distributed redundancy architecture of the present invention also permits the location of the hardware backup element to float, that is, if a primary element fails, the functions can be transferred over to the backup element. When the failed primary element is replaced, the replacement hardware can serve as the hardware backup. If one or more of the primary processes on a particular element experiences a software fault, the processor on the line card may terminate and restart the failing process or processes. Once the process or processes are restarted, a copy of the last known dynamic state (i.e.

Abstract: A cell analysis and sorting apparatus is capable of monitoring over time the behavior of each cell in a large population of cells. The cell analysis and sorting apparatus contains individually addressable cell locations. Each location is capable of capturing and holding a single cell, and selectively releasing that cell from that particular location. In one aspect of the invention, the cells are captured and held in wells, and released using vapor bubbles as a means of cell actuation. In another aspect of the invention, the cells are captured, held and released using electric field traps.

Abstract: The present invention pertains to polymeric compositions useful for the suppression or elimination of outgassing of volatile components generated from photoresist polymers during lithographic construction. In resists of the invention, an aromatic compound is mixed with a photoresist composition, such that the aromatic compound suppresses or eliminates outgassing of volatile components upon exposure of the resist to radiation. The aromatic additive is preferably an aromatic polymer and in at least some instances can be substituted with at least one electron-donating group or electron-withdrawing group to enhance its stabilizing effects. In one embodiment, the aromatic compound can be an additive to a resist composition. In another embodiment, the aromatic compound can be incorporated into the polymeric backbone of the resist composition.

Abstract: Surgical ablation instruments are disclosed for creating lesions in tissue, including cardiac tissue for treatment of arrhythmias and other diseases. The hand held instruments are especially useful in open chest or port access cardiac surgery for rapid and efficient creation of curvilinear lesions to serve as conduction blocks. Photoablative instruments are disclosed that can achieve rapid and effective photoablation through the use of distributed (e.g., diffuse or defocused) radiant energy.

Abstract: The present invention provides methods for operating a computer system that call for executing a plurality of modular processes, providing a data file for use by the plurality of the processes, and incorporating a view identification within each of the plurality of processes to define data accessible by each process within the data file. The processes can include, for example, two identical processes that are executed simultaneously to access the same data within the data file in accordance with the same incorporated view identification.

Abstract: A light energy delivery head is provided which, in one aspect, mounts laser diode bars or other light energy emitters in a heat sink block which is adapted to cool both the emitters and a surface of a medium with which the head is in contact and to which it is applying light energy. In another aspect, various retroreflection configurations are provided which optimize retroreflection of back-scattered light energy from the medium. The size of the aperture through which light energy is applied to the medium is also controlled so as to provide a desired amplification coefficient as a result of retroreflection.

Abstract: The present invention provides a catheter having an x-ray generator unit at its tip which generates x-ray radiation having a wavelength in a range effective for treating biological tissue. In one embodiment, the x-ray generator unit includes a miniature x-ray generator and a miniature transformer that form, in combination, a monolithic device. The transformer includes a primary winding that receives an input voltage in a range of 100 V to 4 kV from a power source, via a flexible cable that runs from the proximal end of the catheter body to its distal end. The transformer further includes a secondary winding that up-converts the input voltage to generate an output voltage in a range of 10 kV to 40 kV to be applied to a cathode of the x-ray generator. The cathode emits electrons in response to the applied voltage, and an extraction electrode guides the emitted electrons to an anode, which is preferably formed of a high-Z refractory metal.

Abstract: The present invention provides improved ion implantation systems and methods in which a high voltage probe is utilized in an ion implantation system to directly measure energy of an ion beam incident on a substrate. More particularly, an exemplary ion implantation system can include an ion source maintained at a high electric potential that generates ions, and a plurality of extraction electrodes that can accelerate the ions to a desired energy. The system further includes an end-station, maintained at ground electric potential, in which a wafer holding for positioning a wafer in the path of an ion beam is disposed. The ion implantation system is further characterized by a high energy probe disposed between a high voltage terminus of the ion source and ground for directly measuring the energy of the ions.

Abstract: The present invention provides a network device including redundant, synchronous central timing subsystems (CTSs) each having a voltage controlled timing circuit for receiving a constant master voltage signal and variable slave voltage signal. Each CTS also includes a control logic circuit for selecting the constant master voltage signal for use by the voltage controlled timing circuit when the CTS is master and for selecting the variable slave voltage signal when the CTS is slave. Using a constant master voltage signal eliminates the need for a separate master oscillator in each CTS. Oscillators are typically expensive, consume significant space on the printed circuit board and have location restrictions on where they may be placed on the printed circuit board.

Abstract: The present invention provides a network device including redundant, synchronous central timing subsystems (CTSs) and local timing subsystems (LTSs) including control circuits for automatically selecting between reference signals from both central timing subsystems. Automatically selecting between reference timing signals allows each LTS to quickly switchover from a failing or failed reference timing signal to a good reference timing signal. Quick switchovers prevent data corruption errors that may result during slow switchovers where a failing or failed reference signal is used for a longer period of time prior to the switch over. In addition, since each LTS independently monitors its received reference timing signals, a problem on one reference timing signal is quickly detected by the LTS and the LTS switches over to the good reference timing signal regardless of whether any other LTSs detect a problem with their received reference timing signals.

Abstract: A method and apparatus are provided in a system for utilizing optical radiation which is applied to a handpiece in contact with a patient's skin to perform a dermatological treatment on the patient to protect the patient by assuring that radiation is applied only when there is good contact between the handpiece and the patient's skin. Good contact is detected by detecting light at a skin contacting surface of the handpiece and enabling the application of radiation only if the detected light is within a selected range. The apparatus assures that the source is not normally enabled and is enabled only when it is safe to apply radiation, and in particular when there is good contact between the handpiece and the patient's skin.

Abstract: The invention provides a method for fault isolation in a computer system, such as a network device. The method calls for providing a plurality of modular processes, and forming groups, based on hardware in the computer system, of one or more of the plurality of modular processes. A fault within a group is detected, and recovery from the detected fault is accomplished without affecting processes or hardware in other groups.

Abstract: A method and apparatus are provided for controlling the temperature of a surface to preheat or precool the surface, to heat or cool the surface to effect a therapeutic treatment or to post-heat or post-cool the surface. A roller, preferably mounted to a handle, is provided which contains a material which is heated or cooled prior to treatment as appropriate so as to undergo a phase change and is then rolled over the surface the temperature of which is to be controlled, gradually undergoing a phase change to return to its initial state as it is rolled over the surface to effect the desired heating or cooling of the surface. The roller preferably has a large internal surface area in contact with the material undergoing the phase change.

Abstract: The present invention provides a network device, such as a network switch or a router, having a high degree of modularity and reliability. The network device includes a data plane and a control plane. The data plane relays datagrams between a pair of receive and transmit network interface ports. The control plane runs management and control operations, such as routing and policing algorithms which provide the data plane with instructions on how to relay cell/packets/frames. Further, the control plane includes an internal control device that is primarily responsible for managing the internal resources of the network device, and a separate external control device that is primarily responsible for operations relating to the interfacing of the network device with an external environment.

Abstract: The present invention provides methods and apparatus for creating insulating layers in Group III-V compound semiconductor structures having aluminum oxide with a substantially stoichiometric compositions. Such insulating layers find applications in a variety of semiconductor devices. For example, in one aspect, the invention provides vertical insulating layers separating two devices, such as photodiodes, formed on a semiconductor substrate from one another. In another aspect, the invention can provide such insulating layers as buried horizontal insulating layers of semiconductor devices.

Abstract: Methods and apparatus are diclosed for removal of biological tissue slices or layers, preferably in the form of lamellar sections (4) of predetermined shape and thickness employing a reference member (12) that engages a target tissue site and cooperates with a cutter (14) in order to remove the tissue segment or lamella. The cutter can include a flexible cutting element such as a wire or band element that is brought into physical contact with a guiding edge (8) integrated with, or otherwise coupled to, the reference member. Alternatively, the cutter can include a stiff rigid blade element (14B) that is maintained in contact with the guiding edge. The cutter is drawn along a path defined by the guide edge through the tissue to sever, at least partialy, a tissue section.

Abstract: An apparatus and method for phototherapy are described in which laser light or other radiation is projected from within a catheter, through a balloon member, and toward the surface of tissue. The light reflected from body fluids or the tissue surface is captured by a collecting device located within the catheter, e.g., within the balloon member, and the intensity of the reflected light is ascertained. The apparatus and method provides for accurately positioning the apparatus against the tissue treatment site.