Abstract: Variable anti-siphon devices are disclosed for use in cerebrospinal fluid shunt systems. Such devices can include a housing with an internal chamber, an adjustable barrier separating the chamber into two cavities, and a diaphragm that seats itself against the adjustable barrier with a seating force that is proportional to the pressure differential across it. The adjustable barrier advantageously allows the level of anti-siphon protection to be modified. In one embodiment, the height of the adjustable barrier may be varied. In another embodiment, the barrier is moved longitudinally within the internal chamber to vary the volume of each chamber.

Abstract: The invention is directed to methods for producing a decellularized organ or part of an organ. A decellularized organ is produced using an isolated organ mechanically agitated to remove cellular membranes surrounding the isolated organ without destroying the interstitial structure of the organ. After the cellular membrane is removed, the isolated organ is exposed to a solubilizing fluid that extracts cellular material without dissolving the interstitial structure of the organ. A washing fluid is used to remove the solubilized components, leaving behind a decellularized organ.

Abstract: The present invention describes methods for producing artificial fascial slings and their subsequent use in treating subjects with urinary incontinence. The invention is based, in part, on the discovery that mesenchymal cells that secrete elastin and collagen, extracellular proteins responsible for elasticity and strength, respectively, can be used to engineer artificial fascia in vitro.

Abstract: A radial flow engine has at least one rotor with an internal cavity that includes a vaporization section and a condensation section. The condensation section is disposed radially inward toward the shaft and the vaporization section extends radially outward adjacent to the surface of the rotor blade. The vaporization section includes a series of pockets for dispersing the cooling fluid within each blade, and a cascaded series of capture protrusions to distribute the liquid coolant to the successive radially-arrayed pockets. A working system includes a centrifugal compressor which feeds a compressed air fuel mixture to an annular combustion chamber that, in turn, feeds the combustion gases along a radial direction to impinge on the surface of the cooled radial flow rotor. Optionally, the system is a regenerative system including a heat exchange sub-assembly which couples heat from the exhaust stream to a position between the compressor and combustion chamber.

Abstract: Methods and compositions for forming polarizing images on an oriented substrate with specially formulated inks are disclosed. The inks can contain a dichroic dye, water, and a humectant. The dichroic inks are particularly advantageous when printed on specially coated molecularly oriented sheets through the technology of ink jet printing. The ink molecules align themselves parallel to the oriented molecules of the oriented sheet thereby forming a light-polarizing image.

Abstract: The present invention provides a method and apparatus for supporting multiple redundancy schemes in a single network device. In one network device, various redundancy schemes are supported including 1:1, 1+1, 1:N, no redundancy or a combination of redundancy schemes. In addition, the redundancy scheme or schemes for physical network device cards (i.e., universal port cards) or ports may be different from the redundancy scheme or schemes for forwarding network device cards. For example, a network manager may want to provide 1:1 or 1+1 redundancy for all universal port cards and/or ports but only 1:N redundancy for each N group of forwarding cards.

Abstract: The present invention provides methods and compositions for preparations of recombinant parvovirus virions with a reduced number of replication competent particles. The compositions of the present invention include nucleic acids encoding parvovirus helper functions which contain at least one non-native intron sequence. The present invention also includes helper function vectors, host cells transfected with the helper function vectors, methods of using the helper function vectors, and recombinant parvovirus virions produced by such methods.

Abstract: A method and apparatus of reducing skin wrinkles, including applying an acoustic pulse or train of pulses to a subsurface region of human skin without damaging or adversely affecting the surface or epidermis layer of the skin. The pulses cause changes in the dermis layer of the skin that result in enhanced smoothness of the epidermis layer of the skin. In particular, the acoustic pulses are applied to the dermis layer at an amplitude and for a period of time sufficient to induce production of new connective tissue that reduces or eliminate of skin wrinkles.

Abstract: A method system, interface and server for establishing a communications call by selecting a B party (6) using an interactive device (16) connected to a public network (10,12), sending called address data for the B party (6) and calling address data for an A party (4) to a communications platform (18) of the public network (10,12), and establishing a call between the A and B parties (4,6) over the public network (10,12) using the communications platform (18) and the called and calling address data. The called address data can be accessed from the public network, and may reside on a server of a messaging network, such as the Internet.

Abstract: A system for controlling end diastolic volume of the heart is disclosed. The system includes an EDV sensor constructed and arranged to measure a parameter related to the end diastolic volume of the heart, and a heart stimulator, responsive to the EDV sensor, constructed and arranged to invoke systole when the measured parameter reaches a predetermined level, the parameter reaching that level prior to termination of diastole. Preferably, the heart stimulator may be a pacemaker. The EDV sensor may be any sensor constructed to measure a parameter related to the end diastolic volume of the heart, or another selected physiological or patho-physiological condition of the heart, including a strain sensor, a stress sensor, a dimension sensor, an impedance sensor, an optical sensor, a microwave sensor, or another sensor constructed to measure a parameter related to the end diastolic volume of the heart, or another selected physiological or patho-physiological condition of the heart.

Abstract: Apparatus and methods are disclosed for non-invasive measurement of blood velocity in otherwise inaccessible body regions, and for correlating such measurements with externally applied pressure to detect and/or assess diseases or physiological abnormalities. The blood velocity measurements can be based on the Doppler shift that occurs when an ultrasonic wave is scattered by moving particles within the blood. Since blood vessels have elastic walls, the geometry of the walls, and therefore the flow dynamics, will change in response to elevated in vivo pressure. The change in resistance to blood flow resulting from these pressure induced changes to the blood vessel wall geometry can provide a measure of intracranial pressure, ophthalmic pressure or various other body conditions that affect blood perfusion.

Abstract: An electrolytic cell includes at least a first and a second, generally planar, membrane-supporting frame each having a plurality of through-holes. Each is sealed to a plurality of annular coupling members located between the frames and generally aligned with a respective through-hole of each frame to thereby define a plurality of sealed conduits through the frames. Each coupling member is attached in a sealed relationship to the first frame by a number of bolts passing through oversized holes in the first frame so as to be capable of movement parallel to the plane of the first frame during assembly of the cell and is sealed to the second frame at a cylindrical interface which provides sealing at a range of distances between the first and second frames. This construction reduces the manufacturing tolerances required for the cell components.

Abstract: The invention features improvements in PRK procedures that relate to preventing non-uniform removal of material from the corneal surface. It has been realized that photoablation by-products resulting during the PRK procedure can affect the accuracy and the predictability of the procedure. Under certain conditions, the plume of photoablation by-products that have left the corneal surface can non-uniformly redeposit onto the ablation area and thus affect the uniformity of subsequent material removal. The plume of photoablation by-products, in the space above the corneal surface, can also non-uniformly affect the escape of further photoablation products from the surface. In addition to the plume effects, it has been realized that the hydration level of the corneal tissue during the PRK procedure can vary over the ablation area and likewise non-uniformly affect the PRK procedure.

Abstract: The present invention relates generally to the treatment of volume deficiency disorders of body structures and related syndromes, and more particularly to devices that deliver fluid at a controlled pressure into an interstice of a patient to effect tissue expansion and to surgical procedures for augmenting volumetrically deficient structures or for reconstructing damaged natural body tissue by attachment of tissue segments cultivated by dilation. Methods of delivering fluid at a controlled pressure into an interstice are also disclosed.

Abstract: An optical transmissive, light-diffusing, fiber tip assembly having a radiation-scattering particles incorporated therein and a reflective end surface is disclosed for use in phototherapy. As radiation propagates through the fiber tip, a portion of the radiation is scattered in a cylindrical (or partially cylindrical) pattern along the length of the fiber tip. Radiation which is not scattered during this initial pass through the tip is reflected by at least one surface of the assembly and returned through the tip. During this second pass, the remaining radiation (or at least a major portion of this returning radiation) again encounters the scatterers which provide further radial diffusion of the radiation. Preferably, the scattering medium and the reflective end cap interact to provide a substantially uniform axial distribution of laser radiation over the length of the tip apparatus.

Abstract: Non-occluding catheters and methods for delivering energy to a vessel wall without occluding blood flow through the vessel wall are disclosed. In particular, the invention uses an energy distributor connected to an expansion mechanism and a waveguide. The expansion mechanism causes the distributor to come into close proximity with a target region in the vessel wall, while maintaining at least one fluid passageway for blood flow throughout the instrument.

Abstract: Wrapping apparatus for wrapping an object such as an agricultural bale with stretched film has a powered stretch film dispenser mounted to a swing arm disposed above a bale support; the swing arm is connected to a drive unit by which the arm is swung causing the dispenser to execute continuous circular motion about a bale on the bale support, the latter being operable to spin the bale slowly about an axis in the plane of motion of the dispenser. The dispenser derives power for positively dispensing wrapping film from the arm drive unit by way of a mechanical drive transmission. In use, turns of film are wrapped in overlapping, angularly displaced fashion about the bale and the rate at which film is dispensed always bears a fixed relationship to the speed of the drive unit, the angular speed of the swing arm and the rate at which turns are wrapped around the bale.

Abstract: A semiconductor P-I-N detector including an intrinsic wafer, a P-doped layer, an N-doped layer, and a boundary layer for reducing the diffusion of dopants into the intrinsic wafer. The boundary layer is positioned between one of the doped regions and the intrinsic wafer. The intrinsic wafer can be composed of CdZnTe or CdTe, the P-doped layer can be composed of ZnTe doped with copper, and the N-doped layer can be composed of CdS doped with indium. The boundary layers is formed of an undoped semiconductor material. The boundary layer can be deposited onto the underlying intrinsic wafer. The doped regions are then typically formed by a deposition process or by doping a section of the deposited boundary layer.

Abstract: An ion implantation system for producing silicon wafers having relatively low defect densities, e.g., below about 1×106/cm2, includes a fluid port in the ion implantation chamber for introducing a background gas into the chamber during the ion implantation process. The introduced gas, such as water vapor, reduces the defect density of the top silicon layer that is separated from the buried silicon dioxide layer.

Abstract: An infuser for transferring hazardous treatment fluids to and from a medical application includes a spill containing housing having a medical application connecting element and a syringe seat. The syringe seat of the infuser leads to a syringe connecting element that provides a fluid coupling between the syringe and a fluid passage leading to the medical application connecting element. The interior of the housing can be sealed against leaks, for example, by providing the housing in two portions with a gasket provided between the portions. A fluid tight coupling between the syringe and the interior of the housing may be created by integrally forming a septum with the gasket and coupling the syringe with the syringe connecting element through the septum. The infuser can also be provided with two syringe seats so that two different fluids can be transferred. In one embodiment, a second syringe connecting element is provided in fluid-tight communication with a second fluid passage.