Abstract: The invention provides a system and method for trans-fetal membranes transport. A source of ultrasound sonication is used to deliver ultrasound sonication to fetal membranes to enhance the permeability of the fetal membranes of a gestational sac. In one embodiment, a device is used to collect substances transported from the interior of the gestational sac to the exterior of the gestational sac, such as amniotic or coelomic fluid. In another embodiment a device is used to deliver one or more substances, such as a drug, to an external surface of the fetal membranes.

Abstract: A fragrance tester for applying a fragrance comprising a mechanism for providing a visible indication and a fragrance applicator for applying the fragrance, the tester adapted to apply the fragrance in proximity of said visible indication.

Abstract: A method for treating a disease selected from diabetes mellitus and atherosclerosis, and a method for reducing triglycerides and/or increasing HDL cholesterol levels in the plasma of a subject. The method comprises administrating to a subject an effective amount of crude Dunaliella powder, optionally together with an activator of nuclear receptors.

Abstract: Provided is a core/multishell semiconductor nanocrystal including a core and multiple shells, which exhibits a type-I band offset and high photoluminescence quantum yield providing a bright tunable emission covering the visible range from about 400 nm to NIR over 1600 nm.

Abstract: A number of apparatuses are provided, for sensing and/or emitting energy along one or more desired apparatus line of sights (LOS) with respect to the respective apparatus. In at least one embodiment, the apparatus includes an assembly that is rotatably mounted on a base with respect to a switching axis. The assembly has two or more sensing/emitting units, each having a respective sensing/emitting unit line of sight (ULOS). Each sensing/emitting unit has an operative state, wherein the respective unit ULOS is pointed along a LOS of the apparatus for sensing and/or emitting energy along the LOS, and a corresponding inoperative state, where the respective unit ULOS is pointed along a direction different from this LOS. A switching mechanism enables switching between the sensing/emitting units to selectively bring a desired sensing/emitting unit exclusively into its respective operative state while concurrently bringing a remainder of the sensing/emitting units each to a respective non-operative state.

Abstract: There is provided a system for supplying power to a site having a load. The system comprises a number n of power source units, the value of n being greater than or equal to 3. The system further comprises a number t?tmax of loads groups, each load group having a number i of inputs. The value of i is greater than or equal to 2 and less than the value of n. Each load group receives power from i power source units, such that each load group is connected to a unique combination of i power source units. tmax is such that every possible combination of i power source units is connected to a unique load group.

Abstract: Provided is a novel, isolated polypeptide including an amino acid sequence of SEQ. ID. NO: 2 or SEQ. ID. NO: 4, and the nucleic acid molecule which encodes it. The polypeptide may be used in a method for treating various diseases including cancer, immune associated, viral and inflammatory diseases.

Abstract: A system and method are disclosed for providing suction to a target area, in which suction is induced via pumping action in proximity to the target area via a pump head that is integral with an enclosure that is configured for covering the area. The pump head has an inlet that projects directly into the internal volume of the enclosure.

Abstract: A cutting tool holder adapted for mounting thereon a cutting insert having a top face, a bottom face and formed with an insert bore having an inner surface extending between the top and the bottom face. The holder comprises a seat defined by a bottom surface and at least one side wall angled to the bottom surface, a seat bore with a bore axis having an open end at the bottom surface of the seat, and a securing mechanism for securing the cutting insert in the seat. The securing mechanism comprises a securing pin received within the seat bore and having a body with an outer surface extending between a proximal end and a distal end of the body and defining a pin axis therealong.

Abstract: A method and system for non-invasive determination of at least one condition of a living organism selected from physiological conditions and emotional states of the living organism are described. The method comprises sensing electromagnetic waves emanated from a skin portion in an extremely high frequency (EHF) band, and obtaining from the sensed electromagnetic waves at least one unique biometric signature of the living organism indicative of the organism condition. The system includes an antenna array unit configured for sensing the electromagnetic waves emanated from the skin portion; and a receiving unit configured and operable for obtaining the unique biometric signature. The sensed electromagnetic waves are indicative of bioelectric activity of neurally connected and electromagnetically interacting structures distributed in a skin portion of the living organism.

Abstract: Methods, systems and apparatuses are provided for producing delivery devices, preferably for oral intake of an agent. In the broadest aspect, the method comprises assembling one or more layers comprising one or more materials with an agent or an agent-releasing formulation to form an intergraded, preferably laminated device; folding said integrated delivery device to form a folded integrated delivery device; and at least partially enclosing said folded delivery device to a form suitable for oral delivery. Preferably, the integrated device comprise a first external layer of a first material; a frame of a second material mounted on the first external layer; an agent-releasing formulation housed within the frame; and a second external layer of the first material mounted on the frame.

Abstract: The invention provides a method for learning and identification of message types in a network in which the learning and identification is based solely upon information contained in messages in the network. In one embodiment, the method includes comparing a current message with one or more previously defined message structures and applying a comparison method in order to infer whether the structure of the current message conforms to any one of the previously defined message structures. The invention also provides a method for classifying a collection of messages input or output from a computational node in which the set of messages is portioned into subsets of similar messages, and a structure of the messages of each subset is characterized. The invention further provides a method for inferring causal relations between a message type input to a computational node in a network and message type output from the computational node in the network using one or more statistical tests.

Abstract: Disclosed are devices and methods for administration of charged drugs to tissues of the oral cavity and for intra-tissue administration. The disclosed drug applicator for intra-tissue use includes an introducer such as a needle or catheter that is adapted to penetrate into a living tissue. The introducer has a drug-providing portion, and the applicator has current-generating element to pass through it an electrical current. Passing an electrical current through the drug-providing portion causes the drug to eject into treated tissue. Also disclosed are charged drugs suitable for iontophoretic administration, which include a bioactive agent encapsulated in charged nano-particles.

Abstract: The present invention provides an explosive composition of substantially reduced sensitivity and low flammability, being definable as an extremely insensitive detonating substance (EIDS) according to UN Regulations for the Transport of Dangerous Goods and comprising one or more explosive material 42-58% vol., one or more fire retardant material 15-26% vol. and a binder 20-36% vol.

Abstract: A method and system for adipose tissue treatment. The system of the invention includes an applicator configured to apply negative pressure pulses to a skin surface when activated by a controller, where the negative pressure is created during a time interval in which the flow of water through the cell membrane is not significant. An intensity of the negative pressure is used that causes selective damage to fat cells.

Abstract: A ceramic armor tile for attaching internally behind a wall of a structure and for cooperation in conjunction therewith, such that the wall acts as an external protective layer of the armor.

Abstract: An extended forward tow, single rail saddlemount or tow bar is disclosed. The tow bar allows a first towing truck to mount a second truck, facing forward, behind the first truck, in order to tow the second truck. The tow bar allows the towed truck to face forward during transport, thus allowing for normal loads and stresses of movement on the towed truck, rather than the much higher high wind loads and unusual stresses imposed by a rear-ward facing tow. The saddlemount is also designed to minimize the required vertical rise on the towed truck, which also avoids additional stresses during loading and unloading onto the towing truck. Lower stress is achieved by using a pivot pin nearer the towed truck rather than the usual pivot pin or king pin on the towing truck.

Abstract: Methods and systems are provided for generating a digital model of at least a part of an object referenced to a global coordinate system. An initial digital model, referenced to a local coordinate system associated with the optical device and representative of the respective part, is provided using an optical device at a relative location with respect to the object. The optical device has a plurality of visually exposed optical markers, at known locations with respect to the optical device and referenced to a marker coordinate system. The location of the optical device with respect to an external camera arrangement is determined, based on relating the relative locations of the markers with respect to one another, as they appear from a viewpoint of the external camera arrangement, to their relative locations as referenced to the marker coordinate system. The camera viewpoint is at a known location referenced to the global coordinate system.

Abstract: The increase in antibacterial resistance has created the demand for new antibiotics. The present invention relates to a more potent antibiotic that targets the enzyme glutamate racemase from known glutamate racemase inhibitors. Glutamate racemase catalyses the interconversion of L-glutamate to D-glutamate, making D-glutamate available, which is required for bacterial peptidoglycan biosynthesis. Knockout mutations have shown glutamate racemase to be necessary for bacterial cell survival and, before the present invention, no antibiotic on the market targeted this enzyme. The present invention relates to new, ligand based glutamate racemase inhibitors, developed using software to extract a pharmacophore model from a group of known glutamate racemase inhibitors. Forty-seven (47) known inhibitors were collected from the literature and several pharmacophore models were extracted therefrom.