Abstract: Halogenated contaminants are decomposed in a fluid and solid by reacting such matrix with a reagent composed of a non-alkali metal, a polyalkyleneglycol/or Nixolens.sup.R and a hydroxide/or alcoholate. Further, this reagent combined with certain solid carriers forms an immobilized decontamination bed to remove halogenated contaminants continuously from a fluid.
Type:
Grant
Filed:
June 12, 1995
Date of Patent:
September 2, 1997
Assignee:
Sea Marconi Technologies di Wander Tumiatti S.A.S.
Abstract: Utilization of the Tarchanthus camphoratus and its derivatives in formulations and compositions having insect repellant, anti-irritant, anti-edema, decongestant and soothing properties.
Type:
Grant
Filed:
July 10, 1995
Date of Patent:
March 4, 1997
Assignee:
Gisquare Technologies B.V.
Inventors:
Guido Rovesti, Gabriele Segalla, Pietro La Fratta, Michele G. Di Schiena
Abstract: Imidazole derivatives having A II antagonist activity, of Formula I, the processes for the preparation thereof, pharmaceutical compositions containing them and the use thereof as therapeutic agents. The described compounds having A II antagonist activity can be used in various cardiovascular disorders.
Type:
Grant
Filed:
March 17, 1995
Date of Patent:
December 24, 1996
Assignee:
Istituto Luso Farmaco D'Italia S.p.A.
Inventors:
Aldo Salimbeni, Fabio Paleari, Jacques Mizrahi, Carlo Scolastico
Abstract: A method for treating a patient suffering from any of osteoporosis, Paget's disease and hypercalcemia by intranasally administering to said patient by spray a calcitonin solution consisting of calcitonin dissolved in a 0.9% aqueous sodium chloride solution free of quaternary ammonium compounds and surfactants, the calcitonin being in a concentration of 100-5000 IU per ml. of composition.
Abstract: Pharmaceutical compositions containing ACTH(1-24) are effective in the treatment of shock conditions and of respiratory and cardiocirculatory insufficiency. The compositions of the invention may be administered by parenteral or inhalatory route at a dosage ranging from 1 to 10 mg of active principle.
Abstract: Compounds of formula I: ##STR1## in which the various R groups have the meanings defined in the disclosure are useful as medicaments for the treatment of hepatobiliary diseases.
Abstract: A process for the purification of glycerylphosphorylcholine (GPC) and glycerylphosphorylethanolamine (GPE) from crude mixtures by eluting the latter on a cationic resin in acid form equilibrated in an anhydrous solvent, washing the resin with alcohol or a hydrated mixture thereof followed by washing with water, and then eluting on a strong basic resin in OH form to separate purified GPC and GPE.
Abstract: 3-L-(5-thioxo-L-prolyl)thiazolidine-4-carboxylic acid and the derivatives thereof have valuable immunostimulating, antioxidant, antiradical and antiageing properties. They are prepared by thionating the corresponding 3-L-pyroglutamyl-L-thiazolidine-4-carboxylic acid derivatives or by condensing 5-thioxo-L-proline with the corresponding L-thiazolidine-4-carboxylic acid derivatives.
Type:
Grant
Filed:
January 16, 1991
Date of Patent:
May 18, 1993
Assignee:
Poli Industria Chimica S.p.A.
Inventors:
Stefano Poli, Lucio Del Corona, Germano Coppi
Abstract: A new crystalline form of magnesium valproate obtained by reacting valproic acid with magnesium alkoxides in alcoholic solution is described.The new crystalline form is endowed with enhanced bioavailability and may be used in a particularly pure form to prepare pharmaceutical compositions which are useful for treating Central Nervous System pathologies.
Abstract: A monoclonal antibody against Doxorubicin and other anthracycline derivatives, being the monoclonal antibody able to selectively recognize epitopes located in correspondence or in proximity of the aromatic D ring of the anthracycline molecule, is described.
Type:
Grant
Filed:
January 16, 1991
Date of Patent:
January 5, 1993
Assignee:
Istituto Nazionale per lo Studio e la Cura dei Tumori
Inventors:
Andrea Balsari, Maria I. Colnaghi, Mario Ghione
Abstract: Compounds of general formula I ##STR1## wherein R.sub.1 is hydrogen or hydroxy, and the hydroxy group at the 7-position can be either in .alpha. or .beta. configuration, are valuable in human therapy. Compounds I can be prepared by fluorination of the suitably protected 6.alpha.-hydroxy-7-keto-derivatives.
Abstract: Compounds of general formula I ##STR1## wherein R.sub.1 is hydrogen or hydroxy, and the hydroxy group at the 7-position can be either in .alpha. or .beta. configuration, are valuable in human therapy. Compounds I can be prepared by reacting with succinic acid carboanions the corresponding derivatives which have previously been protected, and subsequently deprotecting and decarboxylating them.
Abstract: A process for the extraction of eicosapentaenoic (EPA) and docosahexaenoic (DHA) acid esters from crude fish oils, by means of transesterification with ethanol and H.sub.2 SO.sub.4 and two-step molecular distillation.
Abstract: 3-(L-pyroglutamyl)-L-thiazolidine-4-carboxylic acid and derivatives thereof are prepared by condensing L-pyroglutamic acid or its substitution products, either in the presence of dicyclohexylcarbodiimmide or the like, or by condensation of active derivatives of L-pyroglutamic acid with 4-thiazolidine-carboxylic acid derivatives.
Abstract: Bile acid derivatives of formula I ##STR1## wherein: R is hydrogen or hydroxy;X is a carboxy or a SO.sub.3 H group, have valuable pharmacologic properties.
Abstract: The present invention relates to an acrylic acid synthetic polymer, said polymer being cross-linked, having high molecular weight and containing 56% to 68% by weight carboxy groups (--COOH), characterized in that it contains no more than 10 ppm solvent; and to a process for the preparation thereof.
Abstract: Gold and silver are stripped from activated carbon on which they are adsorbed as cyanide complexes by subjecting the activated carbon to a stripping solution comprising as the strippant an effective amount of a compound containing the carboxylate functionality. The compound is preferably selected from benzoic and substituted benzoic acids, and polyacrylic acids of less than about 100,000 m.w.
Type:
Grant
Filed:
September 26, 1990
Date of Patent:
December 17, 1991
Assignee:
Drew Chemical Corporation
Inventors:
Everett J. Fuller, Lionel B. Luttinger, Mark G. Lang