Patents Represented by Attorney Ward and Smith P.A.
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Patent number: 7963724Abstract: A primary earth penetrating mandrel formed of a hollow shell steel plate octagonal in cross-section has an upper end and a blunt lower end joined by an upwardly and outwardly tapered wall. The mandrel is driven downwardly in the earth to simultaneously form a vertical tapered cavity while compacting the sidewall of the cavity to provide structural integrity. The mandrel is then moved upwardly from the bottom of the cavity and aggregate is deposited in the bottom of the cavity following which the mandrel is lowered so that its blunt lower end engages the deposited aggregate and densifies the aggregate by vertical vibratory action and static force with these steps being repeated until the pier top is near the surface of the earth at which time the upper aggregate portions are densified by either the primary mandrel or a secondary mandrel having a substantially larger lower end surface than the lower end surface of the primary mandrel.Type: GrantFiled: August 1, 2007Date of Patent: June 21, 2011Assignee: Geopier Foundation Company, Inc.Inventors: Kord J. Wissmann, Alan L. Moxhay, Nathaniel S. Fox
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Patent number: 7959955Abstract: A unique, synergistic formulation for the treatment of first-degree skin burns is provided for topical use and alleviates the full spectrum of symptoms and concerns associated with epidermal burns, including pain, blistering, redness, swelling, compromised skin integrity, risk of infection and scarring. The formulation contains natural homeopathic extracts combined with a pharmaceutically acceptable carrier suitable for topical administration. The formulation includes the following homeopathic extracts: Cantharis vesicatoria, Echinacea anqustifolia, Calendula officinalis and Hypericum perforatum.Type: GrantFiled: June 11, 2008Date of Patent: June 14, 2011Assignee: The Akshay Wellness Group, Inc.Inventor: Sai S. Manickam
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Patent number: 7943030Abstract: A series of microactuators for manipulating small quantities of liquids, and methods of using these for manipulating liquids, are disclosed. The microactuators are based on the phenomenon of electrowetting and contain no moving parts. The force acting on the liquid is a potential-dependent gradient of adhesion energy between the liquid and a solid insulating surface.Type: GrantFiled: August 3, 2007Date of Patent: May 17, 2011Assignee: Advanced Liquid Logic, Inc.Inventor: Alexander David Shenderov
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Patent number: 7939021Abstract: A droplet actuator with cartridge is provided. According to one embodiment, a sample analyzer is provided and includes an analyzer unit comprising electronic or optical receiving means, a cartridge comprising self-contained droplet handling capabilities, and a wherein the cartridge is coupled to the analyzer unit by a means which aligns electronic and/or optical outputs from the cartridge with electronic or optical receiving means on the analyzer unit. According to another embodiment, a sample analyzer is provided and includes a sample analyzer comprising a cartridge coupled thereto and a means of electrical interface and/or optical interface between the cartridge and the analyzer, whereby electrical signals and/or optical signals may be transmitted from the cartridge to the analyzer.Type: GrantFiled: August 14, 2007Date of Patent: May 10, 2011Assignees: Advanced Liquid Logic, Inc., Duke UniversityInventors: Gregory F. Smith, Ryan A. Sturmer, Philip Y. Paik, Vijay Srinivasan, Michael G. Pollack, Vamsee K. Pamula, Keith R. Brafford, Richard M. West
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Patent number: 7919330Abstract: Methods of improving microfluidic assays are disclosed. Assays can be improved (better signal to noise ratio) by using sessile drop evaporation as an analyte concentration step (enhanced signal) and repeated passes of wash droplets as a means to reduce non-specific binding (noise reduction). In addition multiple massively parallel analyses improve the statistical precision of the analyses.Type: GrantFiled: June 15, 2006Date of Patent: April 5, 2011Assignee: Advanced Liquid Logic, Inc.Inventors: Peter Patrick de Guzman, Wayne Po-Wen Liu, Uichong Brandon Yi, Chang-Jin Kim
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Patent number: 7909540Abstract: A portable air supply system includes a main frame for nesting paired air SCUBA cylinders therein. Saddle arms are connected for engaging the frame to pontoons of an inflatable boat. A pair of baskets are connected for carrying umbilical lines. A control box controls air flow, monitors diver status, and provides a communication link.Type: GrantFiled: May 15, 2009Date of Patent: March 22, 2011Inventor: Hendry R. Leishman
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Patent number: 7901947Abstract: The present invention relates to droplet-based particle sorting. According to one embodiment, a droplet microactuator is provided and includes: (a) a suspension of particles; and (b) electrodes arranged for conducting droplet operations using droplets comprising particles. A method of transporting a particle is also provided, wherein the method includes providing a droplet comprising the particle and transporting the droplet on a droplet microactuator.Type: GrantFiled: December 15, 2006Date of Patent: March 8, 2011Assignee: Advanced Liquid Logic, Inc.Inventors: Michael G. Pollack, Vamsee K. Pamula, Vijay Srinivasan
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Patent number: 7901159Abstract: An apparatus and method for forming a support pier having a single or multiple compacted aggregate lifts in a soil matrix, wherein the apparatus includes a vertical, hollow tube with a bulbous leading end or head element that is forced into the soil matrix. The hollow tube includes a mechanism for releasing aggregate from the lower head element of the tube as the tube is lifted incrementally. The same hollow tube is then utilized to compact the released aggregate. The process may be repeated to form a series of compacted lifts comprising a pier.Type: GrantFiled: May 11, 2007Date of Patent: March 8, 2011Assignee: Geopier Foundation Company, Inc.Inventor: Nathaniel S. Fox
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Patent number: 7860731Abstract: A system and method are provided for obtaining medical data from a user, analyzing it and providing a feedback message. Existing home medical devices are connected to a data translation device which transmits the data to a cellular phone. The cellular phone transmits the data to a server where it is analyzed and a feedback message is transmitted back to the phone.Type: GrantFiled: December 20, 2005Date of Patent: December 28, 2010Assignee: Confidant Hawaii, LLCInventors: David Bryan Jackson, Ralph Ellsworth Cook, Stephen R. Cole
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Patent number: 7858935Abstract: A method and system for conducting event-streamed spectrum imaging concurrently collects electron and spectral signals resulting from a raster scan of a sample. The signals are formatted and assembled as a packet stream. The packet stream is transmitted to a host where it is buffered, stored and processed.Type: GrantFiled: June 28, 2007Date of Patent: December 28, 2010Assignee: 4Pi Analysis, Inc.Inventors: Scott David Davilla, Jayanthi Subramanian Suryanarayanan
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Patent number: 7851184Abstract: The present invention relates to a droplet-based nucleic acid amplification method and apparatus.Type: GrantFiled: December 15, 2006Date of Patent: December 14, 2010Assignees: Advanced Liquid Logic, Inc., Duke UniversityInventors: Michael G. Pollack, Philip Y. Paik, Vamsee K. Pamula
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Patent number: 7829513Abstract: An organic cleaning composition includes effective amounts of citric acid, acetic acid and malic acid. The acids are mixed into a carrier. Optionally glycerin and soybean oil may also be added to the mixture. Preferably the acids are mixed with water wherein the water is about ninety-six point five percent (96.5%) to about ninety-seven point five percent (97.5%) by weight of the mixture.Type: GrantFiled: March 12, 2009Date of Patent: November 9, 2010Assignee: Greenology Products, Inc.Inventors: Adam McCarthy, David Andrew Gordon
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Patent number: 7822510Abstract: Systems for controlling a droplet microactuator are provided. According to one embodiment, a system is provided and includes a controller, a droplet microactuator electronically coupled to the controller, and a display device displaying a user interface electronically coupled to the controller, wherein the system is programmed and configured to permit a user to effect a droplet manipulation by interacting with the user interface. According to another embodiment, a system is provided and includes a processor, a display device electronically coupled to the processor, and software loaded and/or stored in a storage device electronically coupled to the controller, a memory device electronically coupled to the controller, and/or the controller and programmed to display an interactive map of a droplet microactuator.Type: GrantFiled: August 14, 2007Date of Patent: October 26, 2010Assignees: Advanced Liquid Logic, Inc., Duke UniversityInventors: Philip Y. Paik, Michael G. Pollack, Ryan A. Sturmer, Gregory F. Smith, Keith R. Brafford, Vamsee K. Pamula
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Patent number: 7815871Abstract: The present invention relates to a droplet microactuator system. According to one embodiment, the droplet microactuator system includes: (a) a droplet microactuator configured to conduct droplet operations; (b) a magnetic field source arranged to immobilize magnetically responsive beads in a droplet during droplet operations; (c) a sensor configured in a sensing relationship with the droplet microactuator, such that the sensor is capable of sensing a signal from and/or a property of one or more droplets on the droplet microactuator; and (d) one or more processors electronically coupled to the droplet microactuator and programmed to control electrowetting-mediated droplet operations on the droplet actuator and process electronic signals from the sensor.Type: GrantFiled: December 15, 2006Date of Patent: October 19, 2010Assignee: Advanced Liquid Logic, Inc.Inventors: Vamsee K. Pamula, Vijay Srinivasan, Michael G. Pollack, Allen E. Eckhardt, Philip Y. Paik
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Patent number: 7816121Abstract: A droplet actuation system is provided including a droplet actuation device including a substrate that includes electrodes for conducting droplet operations; temperature control means for heating and/or cooling a region of the droplet actuation device and arranged such that a droplet can be transported on the electrodes to a region for heating; and a means for effecting a magnetic field in proximity to one or more of the electrodes sufficient to immobilize magnetically responsive beads in a droplet on the substrate during droplet operations. The system further includes a processor for controlling the electrodes and temperature control means, wherein the processor is programmed, and electrodes and magnetic field are arranged, to cause the electrodes to split a droplet including the magnetically responsive beads yielding a first daughter droplet which includes the magnetically responsive beads and a second daughter droplet without a substantial amount of the magnetically responsive beads.Type: GrantFiled: December 15, 2006Date of Patent: October 19, 2010Assignees: Advanced Liquid Logic, Inc., Duke UniversityInventors: Michael G. Pollack, Philip Y. Paik, Vamsee K. Pamula
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Patent number: 7763471Abstract: Methods of using protein crystallization droplet actuators are provided. Protein sample droplets and reagent droplets are dispensed, transported, and merged to yield an array of crystallization conditions by electrowetting droplet operations in a gap comprising oil filler fluid. The oil filler fluid is doped with a surfactant that enhances droplet operations using the protein sample.Type: GrantFiled: August 16, 2007Date of Patent: July 27, 2010Assignees: Advanced Liquid Logic, Inc., Duke UniversityInventors: Vamsee K. Pamula, Vijay Srinivasan, Michael G. Pollack
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Patent number: 7759132Abstract: Methods for performing microfluidic sampling are provided. The method includes providing a substrate including an arrangement of first, second and third electrodes, wherein the second electrode is interposed between the first and third electrodes. The method additionally includes causing a fluid input to continuously flow to the first electrode and biasing the first, second and third electrodes to a first voltage to cause a portion of the fluid input to spread across the second and third electrodes. The method further includes biasing the second electrode to a second voltage different from the first voltage to form a droplet on the third electrode, the droplet being separate from the fluid input.Type: GrantFiled: October 23, 2006Date of Patent: July 20, 2010Assignee: Duke UniversityInventors: Michael G. Pollack, Vamsee K. Pamula, Richard B. Fair
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Patent number: 7727723Abstract: The present invention relates to a droplet microactuator and to systems, apparatuses and methods employing the droplet microactuator for executing various protocols using droplets. The invention includes a droplet microactuator or droplet microactuator system having one or more input reservoirs loaded with reagents for conducting sequencing protocols, such as the reagents for conducting a pyrosequencing protocol. The invention also includes a droplet microactuator or droplet microactuator system, having one or more input reservoirs loaded with a sample for conducting a pyrosequencing protocol.Type: GrantFiled: December 15, 2006Date of Patent: June 1, 2010Assignees: Advanced Liquid Logic, Inc., Duke University, The Board of Trustees of the Leland Stanford Junior UniversityInventors: Michael G. Pollack, Vamsee K. Pamula, Dwayne J. Allen, Richard B. Fair, Peter Griffin
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Patent number: 7703335Abstract: A load test system includes a test bed frame which extends horizontally along a first axis and includes two rolling beams moveably mounted securely in the test bed frame for being moved to desired position. The rolling beams have plural attachment locations for attaching a test lift device. A hydraulic power station is located spaced perpendicular from the test bed frame along a second axis and includes a hydraulic cylinder with a line connected to the hydraulic cylinder at one end, which is connectable to a test device at another end for applying a load when the test device is attached to the test bed. Beam members connect the hydraulic power station and the test bed frame to form a rigid structure.Type: GrantFiled: July 22, 2008Date of Patent: April 27, 2010Assignee: Tandemloc, Inc.Inventors: John Michael DiMartino, William David DiMartino
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Patent number: 7627914Abstract: An easy to assemble hammock stand is made up of three support members which are connected together. To facilitate connection, plates are located at each end of the support members which include a base and two upwardly extending end members having a plurality of key slot shaped openings with an upward larger entry section. The other of the members to be connected to the key slot shaped opening include corresponding lugs with large head portions which fit in through the larger portion of the key slot openings and then slidably engage securely in a narrower portion of the key slot opening to hold the three members together. Foot members are connected at the joints between the hammock stand member and connected with a combination of a similar key slot shaped arrangement, and conventional screws. The hammock stand components are preferably made of light weight metal tubing and covered with a covering such as wicker mesh.Type: GrantFiled: June 30, 2008Date of Patent: December 8, 2009Assignee: Hatteras Hammocks, Inc.Inventor: Jesse A. Branch, III