Abstract: The invention relates to a process for the preparation of a compound of the formula ##STR1## and, where applicable, its E/Z-isomers, mixtures of E/Z-isomers and/or tautomers, in each case in free form or in salt form, whereinQ is CH or N,Y is NO.sub.2 or CN,Z is CHR.sub.3, O, NR.sub.3 or S,R.sub.1 and R.sub.2 are either each independently of the other hydrogen or unsubstituted or R.sub.4 -substituted C.sub.1 -C.sub.8 alkyl, or together form an alkylene bridge having two or three carbon atoms, and said alkylene bridge may additionally contain a hetero atom selected from the group consisting of NR.sub.5, O and S,R.sub.3 is H or unsubstituted or R.sub.4 -substituted C.sub.1 -C.sub.12 alkyl,R.sub.4 is unsubstituted or substituted aryl or heteroaryl, andR.sub.5 is H or C.sub.1 -C.sub.
Type:
Grant
Filed:
August 13, 1999
Date of Patent:
September 19, 2000
Assignee:
Novartis Crop Protection, Inc.
Inventors:
Thomas Pitterna, Henry Szczepanski, Peter Maienfisch, Ottmar Franz Huter, Thomas Rapold, Marcel Senn, Thomas Gobel, Anthony Cornelius O'Sullivan, Gottfried Seifert
Abstract: Compounds of formula I ##STR1## wherein the substituents R.sub.1 and R.sub.6 and n are as defined in claim 1, and the salts and stereoisomers of the compounds of formula I have good pre- and post-emergence selective herbicidal properties.The preparation of those compounds and their use as herbicidal active ingredients are described.
Type:
Grant
Filed:
December 12, 1996
Date of Patent:
August 15, 2000
Assignee:
Novartis Corporation
Inventors:
Hans-Georg Brunner, Milan Karvas, Kurt Nebel, Georg Pissiotas
Abstract: The invention discloses a novel method for reducing phytotoxicity of Dicamba to crop plants, which comprises co-applying to the crop plants or to the locus thereof a phytotoxicity reducing effective amount of a quinolinyloxy alkanoic acid derivative together with a herbicidally effective amount of Dicamba and salt forms thereof.
Abstract: Compounds of formula (I) ##STR1## in which the substituents W, R.sub.100, R.sub.101 and R.sub.102 are as defined 1; and the pyrazole N-oxides, salts, complexes and stereoisomer of the compounds of (I) have good pre- and post-emergence selective herbicidal properties. The preparation compounds and their use as herbicidal active compounds are described.
Type:
Grant
Filed:
January 6, 1997
Date of Patent:
July 4, 2000
Assignee:
Novartis Corporation
Inventors:
Kurt Nebel, Hans-Georg Brunner, Georg Pissiotas
Abstract: A liquid pesticidal composition, which is substantially free of water, comprising a hydrophobic pesticide or mixture of pesticides dissolved in an organic solvent and comprising as surfactants(1) a butanol-ethoxyate/propoxylate-blockcopolymer having 12-30 mol ethoxylate and 16-48 mol propoxylate, in combination with(2) a branched C.sub.8 -C.sub.18 alcohol ethoxylate having 5-10 mol ethoxylate, and/or(3) a tristyrenephenol-ethoxylate having 8-30 mol ethoxylate, or its phosphate or salt thereof.The compositions include also gels having a viscosity of 500 to 20,000 mPas and comprising additionally a gelling agent.
Abstract: A herbicidal synergistic composition, comprising, besides customary inert formulation auxiliaries, a compound of formula I ##STR1## and a synergistically active amount of at least one active ingredient selected from among the compounds of formula II ##STR2## and of formula III ##STR3## and of formula V ##STR4##
Abstract: The invention relates to compositions comprising: (a) a 4-benzoylisoxazole of formula (I), wherein R, R.sup.1, R.sup.2 and n are as defined in the description and (b) a chloroacetamide herbicide; and their use as herbicides.
Abstract: Compounds of formula (I), wherein A is an unsubstituted or substituted aromatic or non-aromatic, monocyclic or bicyclic heterocyclic radical wherein a ring nitrogen atom may have been replaced by a group ##STR2## R.sub.1 is hydrogen or C.sub.1 -C.sub.3 alkyl; R.sub.2 is hydrogen or C.sub.1 -C.sub.3 alkyl; R.sub.3 is hydrogen, an unsubstituted or substituted C.sub.1 -C.sub.6 alkyl, C.sub.3 -C.sub.6 cycloalkyl C.sub.2 -C.sub.6 alkenyl or C.sub.2 -C.sub.6 alkynyl group, or C(.dbd.O)--R.sub.5, R.sub.5 is C.sub.1 -C.sub.4 alkyl C.sub.1 -C.sub.4 alkoxy, an unsubstituted or substituted phenyl, phenoxy or benzyloxy group, or N(R.sub.6).sub.2, each R.sub.6, independently of the other, is hydrogen, C.sub.1 -C.sub.4 alkyl or unsubstituted or substituted phenyl, X is CH--NO.sub.2, N--CN or N--NO.sub.2 and n is from 1 to 3, in free form or in salt form, and, where appropriate, tautomers of those compounds and the salts thereof, can be used as agrochemical active ingredients and can be prepared in a manner known per se.
Type:
Grant
Filed:
November 22, 1995
Date of Patent:
April 11, 2000
Assignee:
Novartis Corporation
Inventors:
Peter Maienfisch, Jozef Gonda, Olivier Jacob, Laurenz Gsell
Abstract: Compounds of formula ##STR1## wherein n and Z are as defined in claim 1, and, where appropriate, tautomers thereof, in each case in free form or in salt form, can be used as agrochemical active ingredients and can be prepared in a manner known per se.
Type:
Grant
Filed:
July 20, 1998
Date of Patent:
March 7, 2000
Assignee:
Novartis Corp.
Inventors:
Henry Szczepanski, Haukur Kristinsson, Peter Maienfisch, Josef Ehrenfreund
Abstract: Compounds of the formula ##STR1## in which A is an unsubstituted or mono- to tetrasubstituted, aromatic or non-aromatic, monocyclic or bicyclic heterocyclic radical, where one to two of the substituents of A can be selected from the group consisting of halo-C.sub.1 -C.sub.3 alkyl, cyclopropyl, halocyclopropyl, C.sub.2 -C.sub.3 alkenyl, C.sub.2 -C.sub.3 alkynyl, halo-C.sub.2 -C.sub.3 alkenyl, halo-C.sub.2 -C.sub.3 alkynyl, halo-C.sub.1 -C.sub.3 alkoxy, C.sub.1 -C.sub.3 alkylthio, halo-C.sub.1 -C.sub.3 alkylthio, allyloxy, propargyloxy, allylthio, propargylthio, haloallyloxy, haloallylthio, cyano and nitro, and one to four of the substituents of A can be selected from the group consisting of C.sub.1 -C.sub.3 alkyl, C.sub.1 -C.sub.3 alkoxy and halogen;R is hydrogen, C.sub.1 -C.sub.6 alkyl, phenyl-C.sub.1 -C.sub.4 alkyl, C.sub.3 -C.sub.6 cycloalkyl, C.sub.2 -C.sub.6 alkenyl or C.sub.2 -C.sub.6 alkynyl; andX is N--NO.sub.
Abstract: A herbicidal composition comprising, in addition to customary inert formulation adjuvants, as active ingredienta) an antagonistically active amount of at least one compound A selected from the group of compounds of formula A.sub.1 ##STR1## and compounds of formula A.sub.2 ##STR2## compounds of formula A.sub.3 ##STR3## b) a herbicidally effective amount of at least one compound G selected from the group of compounds, preferably having the 2R-configuration, of formula G.sub.1 ##STR4## compounds of formula G.sub.2 ##STR5## c) an acid the pK value of which is smaller than the pK values of compounds G and A.
Type:
Grant
Filed:
December 6, 1996
Date of Patent:
January 25, 2000
Assignee:
Novartis Finance Corporation
Inventors:
Michael Donald Johnson, Cheryl Lynn Dunne, Manfred Hudetz, Daniel Worden Kidder
Abstract: Substituted N-phenyl- and N-heteroarylalkylcarbamates of the formula I ##STR1## in which Q is a group ##STR2## R is halogen, trifluoromethyl, cyano, nitro or C.sub.1 -C.sub.3 haloalkoxy;Z is hydrogen or halogen; orZ and R together in the 2- and 3-position of the phenyl ring form a group --OCF.sub.2 O--;R.sub.1 is C.sub.1 -C.sub.5 alkyl;R.sub.2, R.sub.3, R.sub.4 and R.sub.5, independently of one another, are hydrogen, methyl or ethyl;X is oxygen, sulfur, --SO-- or --SO.sub.2 --;Y is hydrogen, halogen, C.sub.1 -C.sub.3 alkyl, C.sub.1 -C.sub.3 haloalkyl, C.sub.1 -C.sub.3 alkoxy or cyano;n is 0, 1 or 2;n.sub.1 is 0 or 1; andm is 0 or 1,with the proviso that m is 1 if Q is group (1) or (2);and the diastereomers and enantiomers thereof,exhibit pre- and post-emergence herbicidal properties. The preparation of these compounds and their use as herbicidally active ingredients are described.
Type:
Grant
Filed:
August 4, 1998
Date of Patent:
December 7, 1999
Assignee:
Novartis Finance Corporation
Inventors:
Hermann Rempfler, Fredrik Cederbaum, Felix Spindler, Willy Urs Lottenbach
Abstract: The present invention relates to a composition for controlling parasites, in and on animals, which comprises, as active ingredient, a combination, in variable proportions, of at least one parasiticidally active compound, in free form or in salt form, selected from the N-phenyl-N'-benzoyl-urea class of substances, and at least one parasiticidally active compound, in free form or in salt form, selected from the milbemycin, avermectin, milbemycin oxime, moxidectin, ivermectin, abamectin and doramectin classes of substances; to a method of controlling these parasites; to a process for the preparation of this composition; and to the use of this composition.
Type:
Grant
Filed:
January 23, 1998
Date of Patent:
November 30, 1999
Assignee:
Novartis Animal Health US, Inc.
Inventors:
Philip Anthony Lowndes, Stefan Kemmethmuller, Steven Craig Parks, Douglas Irvin Hepler
Abstract: A process for the preparation of primary or secondary amines by hydrogenation of imines with hydrogen at elevated pressure and in the presence of a dinuclear Ir(III) complex having ditertiary diphosphine ligands, halide bridges, halide and hydride ligands, or an Ir(III) halide complex salt containing ditertiary diphosphine ligands, as catalyst, wherein the catalyst corresponds to formula I or Ia or to mixtures of at least two compounds of formula I, at least two compounds of formulae I and Ia, or at least two compounds of formula Ia[(DIP)IrX.sub.q Y.sub.r ].sub.2 (I),[(DIP)X.sub.4 ].sup..crclbar. Me.sup..sym. (Ia),whereinDIP is the ditertiary diphosphine ligand of a ferrocenyldiphosphine the phosphine groups of which are either bonded directly or via a bridge group --CR.sub.v R.sub.w -- to the ortho positions of a cyclopentadienyl ring or are each bonded to a cyclopentadienyl ring of a ferrocenyl, so that a 5-, 6- or 7-membered ring is formed together with the Ir atom;R.sub.v and R.sub.
Type:
Grant
Filed:
January 26, 1998
Date of Patent:
November 16, 1999
Assignee:
Novartis Crop Protection, Inc.
Inventors:
Rafael Sablong, John Anthony Osborn, Felix Spindler
Abstract: Compounds of the formula ##STR1## in which n, q, A, X, G, Y, Z, R, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.7 and R.sub.9 are as defined in claim 1, and, where appropriate, E/Z isomers, E/Z isomer mixtures and/or tautomers thereof, in each case in the free form or in an agrochemically suitable salt form, can be used as agrochemical active compounds and can be prepared in a manner known per se.
Type:
Grant
Filed:
December 6, 1996
Date of Patent:
November 16, 1999
Assignee:
Novartis Corporation
Inventors:
Saleem Farooq, Stephen Trah, Hugo Ziegler, Rene Zurfluh, Alfons Pascual, Henry Szczepanski, Roger Graham Hall
Abstract: Herbicidal compositions comprising S-metolachlor and at least one additional herbicide selected from atrazine, terbuthylazine, flumetsulan, pendimethalin, metosulam, pyridate, glyphosate, glufosinate, cyanazine, dicamba, halosulfuron, prosulfuron, primisulfuron, sulcotrione, metribuzin, BAY FOE 5043, and salts thereof. The compositions may also contain the safener benoxacor.
Type:
Grant
Filed:
February 2, 1998
Date of Patent:
November 9, 1999
Assignee:
Novartis Crop Protection
Inventors:
Manfred Hudetz, Dan Worden Kidder, Robert Franklin Milliken, Norbert Nelgen
Abstract: The invention relates to a herbicidal composition, comprising a compound of formula I ##STR1## and a compound of formula II ##STR2## and/or of formula III ##STR3## or an agriculturally acceptable salt of the compound of formula II and/or III in admixture.
Abstract: A herbicidal composition comprising at least one compound of formula I ##STR1## R.sub.2 is methyl, methoxy or --OCHF.sub.2, R.sub.3 is methyl or --OCHF.sub.2 andE is .dbd.C-- or .dbd.N--, with E being .dbd.N-- when R.sub.2 is methoxy,or an agrochemically acceptable salt of at least one of the compounds of formula I, and a compound of formula II ##STR2## or an agrochemically acceptable salt of the compound of formula II and/or III, in admixture with one another.