Patents Represented by Attorney William J. Stein

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  • .omega.-(1,3-Dithiolan-2-imino) substituted acetic acids
    Patent number: 4131683
    Abstract: .omega.-(1,3-Dithiolan-2-imino) substituted acetic acids are prepared useful as antibacterial agents, inhibitors of cholesterol and fatty acid synthesis, anti-inflammatory agents and as intermediates for cephalosporin antibiotics.
    Type: Grant
    Filed: May 12, 1978
    Date of Patent: December 26, 1978
    Assignee: Richardson-Merrell Inc.
    Inventors: Boyd L. Harrison, Joseph E. Dolfini
  • Acetylsalicylic acid derivatives
    Patent number: 4123544
    Abstract: This invention relates to acetylsalicylic acid derivatives of the formula ##STR1## wherein R is H or OH, which have good analgesic, anti-inflammatory, and antipyretic activity and are, at the same time, free of ulcerogenic activity when administered orally.
    Type: Grant
    Filed: March 2, 1977
    Date of Patent: October 31, 1978
    Assignee: Merrell Toraude S. A.
    Inventors: Henri Kornowski, Bernard Roques, Robert Oberlin, Andre Jondet
  • Nitrofurantoin sustained release tablet
    Patent number: 4122157
    Abstract: A pharmaceutically acceptable layered tablet containing nitrofurantoin in substained release form.
    Type: Grant
    Filed: March 4, 1977
    Date of Patent: October 24, 1978
    Assignee: Richardson-Merrell Inc.
    Inventor: Harold E. Huber
  • 4-Oxo-1-pyridinyl cephalosporin derivatives
    Patent number: 4119775
    Abstract: Novel substituted(4-oxo-1-pyridinyl)acetylaminopenicillin and cephalosporin derivatives are prepared which are useful antibacterial agents.
    Type: Grant
    Filed: October 9, 1975
    Date of Patent: October 10, 1978
    Assignee: Richardson-Merrell Inc.
    Inventors: Ronald E. Bambury, Michael L. Edwards, Laird F. Miller
  • Anthracene derivatives
    Patent number: 4108896
    Abstract: Novel 1,5 and 1,8-bis-basic ketones of anthracene useful for the prevention and inhibition of viral infections are prepared by reacting 1,5 and 1,8 bis(.omega.-haloacyl)anthracenes with a secondary amine.
    Type: Grant
    Filed: December 21, 1972
    Date of Patent: August 22, 1978
    Assignee: Richardson-Merrell Inc.
    Inventors: Laird F. Miller, Robert W. Fleming
  • Androst-4-en-19-ols for the enhancement of libido
    Patent number: 4087524
    Abstract: Derivatives of androst-4-en-19-ol are described which are useful in enhancing the libido and related psychic attitudes in primates.
    Type: Grant
    Filed: February 7, 1977
    Date of Patent: May 2, 1978
    Assignee: Richardson-Merrell Inc.
    Inventors: Joyce F. Grunwell, Vladimir Petrow
  • Method of terminating pregnancy
    Patent number: 4073899
    Abstract: 7.alpha.-methyl-estr-5-ene-3.beta.,17.beta.-diol and 17-acyl esters as contragestative agents.
    Type: Grant
    Filed: February 27, 1976
    Date of Patent: February 14, 1978
    Assignee: Richardson-Merrell, Inc.
    Inventors: Joyce F. Grunwell, John O. Johnston
  • 19-Oxygenated-5.alpha.-androstanes for the enhancement of libido
    Patent number: 4071625
    Abstract: Derivatives of 19-oxygenated-5.alpha.-androstanes are described which are useful in enhancing the libido and related psychic attitudes in mammals.
    Type: Grant
    Filed: February 7, 1977
    Date of Patent: January 31, 1978
    Assignee: Richardson-Merrell Inc.
    Inventors: Joyce F. Grunwell, Vladimir Petrow
  • Androst-4-en-19-ones for the enhancement of libido
    Patent number: 4071624
    Abstract: The present invention concerns androst-4-en-19-ones which are useful in the enhancement of libido and related pyschic attitudes.
    Type: Grant
    Filed: February 7, 1977
    Date of Patent: January 31, 1978
    Assignee: Richardson-Merrell Inc.
    Inventors: Joyce F. Grunwell, Vladimir Petrow
  • Process for preparing 2-(2,2-dicyclohexylethyl)piperidine
    Patent number: 4069222
    Abstract: 2-(2,2-Dicyclohexylethyl)piperidine is prepared via the catalytic hydrogenation of 2-(2,2-diphenylethenyl)pyridine in a single step. High yields are obtained using an anhydrous Raney nickel catalyst.
    Type: Grant
    Filed: April 14, 1976
    Date of Patent: January 17, 1978
    Assignee: Richardson-Merrell Inc.
    Inventors: Stephen W. Horgan, Frank P. Palopoli, Edward J. Schwoegler
  • 3,8-Bis-basic ethers of 6H-dibenzo[b,d]pyran-6-one
    Patent number: 4059702
    Abstract: Bis-basic ethers of 9-sustituted phenanthrene and related 10-oxa and 10-aza derivatives, their method of preparation and their use as pharmaceutical agents for the prevention and inhibition of viral infections are disclosed.
    Type: Grant
    Filed: November 11, 1976
    Date of Patent: November 22, 1977
    Assignee: Richardson-Merrell Inc.
    Inventor: Donald R. Meyer
  • Process for detoxifying influenza B virus
    Patent number: 4057626
    Abstract: A detoxified influenza virus of the B group is obtained by treating an inactivated virus with formaldehyde.
    Type: Grant
    Filed: October 8, 1976
    Date of Patent: November 8, 1977
    Assignee: Richardson-Merrell Inc.
    Inventors: Don P. Metzgar, Raymond H. Newhart
  • .alpha.-Alkylbenzyl lactamimides
    Patent number: 4055561
    Abstract: Novel derivatives of .alpha.-alkylbenzyl lactamimide are useful as anticoagulants.
    Type: Grant
    Filed: April 25, 1973
    Date of Patent: October 25, 1977
    Assignee: Richardson-Merrell Inc.
    Inventors: J. Martin Grisar, George P. Claxton, Robert D. MacKenzie
  • Aminoacetyl-acenaphthenes
    Patent number: 4048230
    Abstract: Novel 3,6-bis basic ketone derivatives of acenaphthene, their preparation and use for the prevention and inhibition of viral infections are disclosed.
    Type: Grant
    Filed: December 21, 1972
    Date of Patent: September 13, 1977
    Assignee: Richardson-Merrell Inc.
    Inventors: Arthur D. Sill, Francis W. Sweet
  • N-(phenylether-substituted benzyl)alkanediamines
    Patent number: 4038412
    Abstract: Novel N-(substituted benzyl)alkanediamines are prepared which are useful for the prevention and inhibition of viral infections.
    Type: Grant
    Filed: August 25, 1975
    Date of Patent: July 26, 1977
    Assignee: Richardson-Merrell Inc.
    Inventors: J. Martin Grisar, George P. Claxton
  • 7 [.alpha.-Amino-.omega.-(2,3-methylenedioxy-phenyl)acylamido]cephalosporan ic acid derivatives
    Patent number: 4033956
    Abstract: Novel 7-[.alpha.-amino-.omega.-(2,3-methylenedioxyphenyl)acylamido] cephalosporanic acid derivatives are prepared which are useful as antibacterial agents.
    Type: Grant
    Filed: July 22, 1975
    Date of Patent: July 5, 1977
    Assignee: Richardson-Merrell Inc.
    Inventors: Raymond C. Erickson, Ronald E. Bambury
  • Androst-4-en-19-ones
    Patent number: 4022769
    Abstract: The present invention concerns derivatives of androst-4-en-19-one which are useful in the enhancement of libido and related psychic attitudes.
    Type: Grant
    Filed: May 13, 1974
    Date of Patent: May 10, 1977
    Assignee: Richardson-Merrell Inc.
    Inventors: Joyce F. Grunwell, Vladimir Petrow
  • 7-[.alpha.-Amino- .omega.-(3,4-methylenedioxyphenyl)acylamido]cephalosporanic acid derivatives
    Patent number: 4020060
    Abstract: Novel 7-[.alpha.-amino-.omega.-(3,4-methylenedioxyphenyl)acylamido]cephalosporan ic acid derivatives are prepared which are useful as antibacterial agents.
    Type: Grant
    Filed: July 22, 1975
    Date of Patent: April 26, 1977
    Assignee: Richardson-Merrell Inc.
    Inventors: Raymond C. Erickson, Ronald E. Bambury
  • 6-[(2,4-Dioxo-1-pyrimidinyl)acylamino]penicillin derivatives
    Patent number: 4008221
    Abstract: Novel [substituted(2,4-dioxo-1-pyrimidinyl)acetylamino]penicillin and cephalosporin derivatives are prepared which are useful antibacterial agents.
    Type: Grant
    Filed: February 9, 1976
    Date of Patent: February 15, 1977
    Assignee: Richardson-Merrell Inc.
    Inventors: Ronald E. Bambury, Michael L. Edwards, Laird F. Miller
  • Xanthene and thioxanthene derivatives
    Patent number: 4008240
    Abstract: Novel 2,7-bis basic alkanol derivatives of xanthene and thioxanthene, their preparation and use for the prevention and inhibition of viral infections are disclosed.
    Type: Grant
    Filed: December 21, 1972
    Date of Patent: February 15, 1977
    Assignee: Richardson-Merrell Inc.
    Inventors: Arthur D. Sill, Francis W. Sweet