Abstract: A cervical tissue cell-gathering device is provided which can be self-administered, and which is so arranged as to protect the sample from contamination as it is inserted and withdrawn from the vagina. An improved method for the preparation of Pap smear slides using such a device is described.
Abstract: Novel 6-[.alpha.-amino-.omega.-(2,3-methylenedioxyphenyl)acylamido] penicillanic acid derivatives are prepared which are useful as antibacterial agents.
Abstract: Novel [substituted(2-oxo-1-pyridinyl)acetylamino] penicillin and cephalosporin derivatives are prepared which are useful antibacterial agents.
Type:
Grant
Filed:
February 9, 1976
Date of Patent:
November 30, 1976
Assignee:
Richardson-Merrell Inc.
Inventors:
Ronald E. Bambury, Michael L. Edwards, Laird F. Miller
Abstract: Novel 6-[.alpha.-amino-.omega.-(3,4-methylenedioxyphenyl)acylamido] penicillanic acid derivatives are prepared which are useful as antibacterial agents.
Abstract: The method comprises administering to an animal an amount of substituted-1-oxo-1H-2-benzopyran-3-carboxylic acid effective to inhibit antigen-antibody reaction in said animal. Representative of the compounds that can be used in the method is sodium 1-oxo-1H-2-benzopyran-3-carboxylate.
Abstract: Novel 2,7-bis-basic derivatives of fluorene, 9-fluorenol and 9-fluorenone, their preparation and use for the prevention and inhibition of virus infections are disclosed.
Type:
Grant
Filed:
December 21, 1972
Date of Patent:
September 28, 1976
Assignee:
Richardson-Merrell Inc.
Inventors:
William L. Albrecht, Stephen W. Horgan, Arthur D. Sill, Robert W. Fleming
Abstract: Water-insoluble therapeutic agents having a tertiary nitrogen capable of being protonated are stabilized and solubilized via the formation of water-soluble lipophilic liquid fatty acid salts.
Abstract: Novel [substituted(2,4-dioxo-1-pyrimidinyl)acetylamino]penicillin and cephalosporin derivatives are prepared which are useful antibacterial agents.
Type:
Grant
Filed:
November 7, 1973
Date of Patent:
May 11, 1976
Assignee:
Richardson-Merrell Inc.
Inventors:
Ronald E. Bambury, Michael L. Edwards, Laird F. Miller
Abstract: Novel [substituted(2-oxo-1-pyridinyl)acetylamino] penicillin and cephalosporin derivatives are prepared which are useful antibacterial agents.
Type:
Grant
Filed:
November 7, 1973
Date of Patent:
May 11, 1976
Assignee:
Richardson-Merrell Inc.
Inventors:
Ronald E. Bambury, Michael L. Edwards, Laird F. Miller
Abstract: Novel triazolocycloalkylhydrothiadiazines and their preparation, which are useful as antisecretory agents, central nervous system stimulants, and central nervous system depressants, are disclosed.
Abstract: Novel bis basic esters of 9-substituted phenanthrene and related 9-oxa and 9-aza derivatives thereof, their preparation and use for the prevention and inhibition of viral infections are disclosed.
Abstract: Pure cis or trans-6-substituted-11-aminoalkylidenemorphanthridines are prepared by treating the corresponding cis or trans-5,6-dihydromorphanthridines with oxygen in the presence of a platinum on carbon catalyst. Among the compounds prepared are:Cis-2-Chloro-11-(3-dimethylaminopropylidene)-6-phenylmorphanthridine, andTrans-2-Chloro-11-(3-dimethylaminopropylidene)-6-methylmorphanthridine.The compounds are useful as antihypertensive and anti-Parkinson agents.
Abstract: Novel bis basic esters of 9-substituted phenanthrene and related 9-oxa and 9-aza derivatives thereof, their preparation and use for the prevention and inhibition of viral infections are disclosed.