Patents Represented by Attorney Wilmer Cutler Pickering Hale and Dorr LLP
  • Patent number: 8127149
    Abstract: A method, system and computer-readable medium for encrypting a file on a computer system based on the content of the file. The method is setting an encryption policy, wherein the encryption policy is at least one attribute related to content of at least one file, scanning at least one file on a computer system for content, matching the content of the scanned at least one file to the at least one attribute set in the encryption policy and encrypting the scanned at least one file with a key in response to a match between the content of the scanned at least one file and the at least one attribute set in the encryption policy. The system is a computer system that includes policy-based encryption software that performs the steps embodied by the method.
    Type: Grant
    Filed: June 29, 2006
    Date of Patent: February 28, 2012
    Assignee: Symantec Corporation
    Inventor: Carey Nachenberg
  • Patent number: 8124369
    Abstract: Rationally-designed LAGLIDADG meganucleases and methods of making such meganucleases are provided. In addition, methods are provided for using the meganucleases to generate recombinant cells and organisms having a desired DNA sequence inserted into a limited number of loci within the genome, as well as methods of gene therapy, for treatment of pathogenic infections, and for in vitro applications in diagnostics and research.
    Type: Grant
    Filed: September 27, 2011
    Date of Patent: February 28, 2012
    Assignee: Duke University
    Inventors: James Jefferson Smith, Derek Jantz, Homme W. Hellinga
  • Patent number: 8124120
    Abstract: Disclosed are hyaluronic acid (HA) compositions including crosslinked, water-insoluble, hydrated HA gel particles. Also disclosed are methods of making the HA compositions, and methods of using the HA composition to augment tissue in a subject.
    Type: Grant
    Filed: December 22, 2003
    Date of Patent: February 28, 2012
    Assignee: Anika Therapeutics, Inc.
    Inventors: Khalid K. Sadozai, Tamera B. Gooding, Kyle Bui, Charles H. Sherwood
  • Patent number: 8124743
    Abstract: The present invention discloses a method of purifying bivalent antibodies or antibody fragments that are active at both Fab sites from a source of antibodies or antibody fragments using a non-chromatographic method that includes inducing the formation of cyclic immunoglobulin aggregates by addition of multivalent hapten to a salt solution of soluble antibodies or antibody fragments, wherein the multivalent hapten possesses a linker between the two haptens effective to prevent the binding of both haptens of the ligand to the same antibody or antibody fragment.
    Type: Grant
    Filed: June 1, 2007
    Date of Patent: February 28, 2012
    Assignee: President and Fellows of Harvard College
    Inventors: Vijay M. Krishnamurthy, Lara A. Estroff, Vincent Semetey, Samuel W. Thomas, George K. Kaufman, Zihni Basar Bilgicer, George M. Whitesides
  • Patent number: 8119597
    Abstract: The invention concerns the use and the production of non-neurotoxic plasminogen activating factors, derived, for example, from the common vampire Desmodus rotundus (DSPA), for therapeutic treatment of stroke in humans. The invention provides a novel therapeutic base for treating stroke in humans.
    Type: Grant
    Filed: August 22, 2008
    Date of Patent: February 21, 2012
    Assignee: Paion GmbH
    Inventors: Mariola Sohngen, Wolfgang Sohngen, Wolf-Dieter Schleuning, Robert Medcalf
  • Patent number: 8119280
    Abstract: A cap assembly for use in an electrochemical cell. The cap assembly includes a tab collection post, a core insert, and at least one current collecting tab connected at one end to an electrode foil in the electrochemical cell, and horizontally connected at the other end to the tab collection post and the core insert. The at least one current collecting tab is disposed between and welded with the tab collection post and the core insert. The cap assembly also includes a shock absorber disposed around the core insert.
    Type: Grant
    Filed: June 9, 2008
    Date of Patent: February 21, 2012
    Assignee: A123 Systems, Inc.
    Inventors: William H. Gardner, Donald G. Dafoe, Lucien Fontaine
  • Patent number: 8119106
    Abstract: The present invention is related to a foamable composition of matter comprising iodine, water, a foam adjuvant, a surface-active agent and a gelling agent. This foamable composition, which may be provided in a propellant free foaming device, or alternatively may further comprise a propellant, evolves into foam, which is effective in the topical treatment and prevention of various skin disorders.
    Type: Grant
    Filed: July 8, 2009
    Date of Patent: February 21, 2012
    Assignee: Foamix Ltd
    Inventors: Dov Tamarkin, Doron Friedman, Meir Eini
  • Patent number: 8119150
    Abstract: The present invention provides a safe and effective insecticide composition suitable for treating a subject infested with a parasitic anthropode or to prevent infestation by an arthropod. The insecticide composition is a foamable composition, including a first insecticide; at least one organic carrier selected from a hydrophobic organic carrier, a polar solvent, an emollient and mixtures thereof, at a concentration of about 2% to about 5%, or about 5% to about 10%; or about 10% to about 20%; or about 20% to about 50% by weight; about 0.1% to about 5% by weight of a surface-active agent; about 0.01% to about 5% by weight of at least one polymeric agent selected from a bioadhesive agent, a gelling agent, a film forming agent and a phase change agent; and (5) a liquefied or compressed gas propellant at a concentration of about 3% to about 25% by weight of the total composition.
    Type: Grant
    Filed: July 6, 2006
    Date of Patent: February 21, 2012
    Assignee: Foamix Ltd.
    Inventors: Dov Tamarkin, Doron Friedman, Meir Eini
  • Patent number: 8119109
    Abstract: The composition of the present invention is geared towards treating hyperhidrosis or any condition involving and/or promoting excessive sweating, typically involving the whole body, include hyperthyroidism or similar endocrine disorders; endocrine treatment for prostatic cancer or other types of malignant disorder; severe psychiatric disorders; obesity and menopause. The foamable composition of the present invention is suitable for treating palmar hyperhidrosis; axillary hyperhidrosis; plantar hyperhidrosis; hyperhidrosis of the trunk and/or the thighs; and facial hyperhidrosis; and any combination of them consisting of a therapeutic foamable composition including: an active agent, suitable for the treatment or prevention of hyperhidrosis.
    Type: Grant
    Filed: March 13, 2007
    Date of Patent: February 21, 2012
    Assignee: Foamix Ltd.
    Inventors: Dov Tamarkin, Meir Eini, Ella Zlatkis
  • Patent number: 8122034
    Abstract: A method and system are provided for processing a search request received from a user operating a text input device. The search request is directed at identifying a desired item from a set of items. Each of the items of the set of items has one or more associated terms. The method includes receiving a query input from a user directed at identifying the desired item. The query input comprises one or more characters input by the user on the text input device. As each character of the query input is received from the user, a group of items having one or more terms matching the characters received thus far of the query input is dynamically identified. The items in this group of items are ordered based on relevance values of the terms matching the characters and on the number of characters of the query input used in identifying the group of items. Identification of the group of items as ordered is transmitted to the user to be displayed on a device operated by the user.
    Type: Grant
    Filed: October 7, 2005
    Date of Patent: February 21, 2012
    Assignee: Veveo, Inc.
    Inventors: Murali Aravamudan, Rakesh D. Barve, Sashikumar Venkataraman, Ajit Rajasekharan
  • Patent number: 8119381
    Abstract: Rationally-designed LAGLIDADG meganucleases and methods of making such meganucleases are provided. In addition, methods are provided for using the meganucleases to generate recombinant cells and organisms having a desired DNA sequence inserted into a limited number of loci within the genome, as well as methods of gene therapy, for treatment of pathogenic infections, and for in vitro applications in diagnostics and research.
    Type: Grant
    Filed: September 26, 2011
    Date of Patent: February 21, 2012
    Assignee: Duke University
    Inventors: James Jefferson Smith, Derek Jantz, Homme W. Hellinga
  • Patent number: 8114385
    Abstract: The invention relates to stable oleaginous cosmetic or therapeutic foam compositions containing certain active agents, having unique therapeutic properties and methods of treatment using such compositions. The foamable composition includes a polyethylene glycol (PEG) or PEG derivative and mixtures thereof, wherein the PEG or PEG derivative is present at a concentration of about 70% to about 96.5% by weight of the total composition; a surface-active agent at a concentration of about 0.1% to less than about 10% by weight of the total composition; and a therapeutically effective amount of at least one active agent.
    Type: Grant
    Filed: December 26, 2006
    Date of Patent: February 14, 2012
    Assignee: Foamix Ltd.
    Inventors: Dov Tamarkin, Doron Friedman, Meir Eini, Alex Besonov
  • Patent number: 8116886
    Abstract: Electrode arrays and systems for inserting same are disclosed. In some embodiments, electrode arrays are provided, the electrode arrays comprising: a passive-bending portion; an active-bending portion coupled to the passive bending portion; a plurality of electrodes located in at least one of the passive-bending portion and the active bending portion; and an actuator that causes the active-bending portion to deflect from the passive-bending portion. In some embodiments, systems for inserting an electrode array in the body are provided, the systems comprising: an insertion module for controllably inserting the electrode array in the body and sensing forces applied to the electrode array; a monitor for providing information to a user; and a controller coupled to the insertion module and the monitor, wherein the controller causes the insertion module to control an amount of force that is applied to the electrode array.
    Type: Grant
    Filed: October 16, 2006
    Date of Patent: February 14, 2012
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Nabil Simaan, Spiros Manolidis
  • Patent number: 8117252
    Abstract: The invention relates to a stand-alone video recording, playback and Monitoring system. It has network switches, non-volatile storage devices, IP cameras, video servers, and NTSC cameras. The system uses communication channels that are WAN/LAN based and can be hard-wired or wireless.
    Type: Grant
    Filed: December 24, 2003
    Date of Patent: February 14, 2012
    Inventor: Glen D. Schaff
  • Patent number: 8117024
    Abstract: Systems and methods for automatically processing candidate resumes and job specifications expressed in natural language into a normalized form using frequency analysis. A database of elements is provided in which each element is expressed in natural language and at least some of which are associated with a corresponding set of synonymous words or phrases. Candidate resumes and job specifications are received in electronic form and expressed in natural language. The candidate resumes and job specifications are analyzed to extract elements expressed in candidate resumes and job specifications. The extracted elements are compared to the database. For each extracted element, the most frequent element or synonym is identified an used as a common form for the extracted element. A set of candidate resumes is matched with a corresponding job specification by comparing the set of elements expressed in common form for the resumes with the set of elements expressed in common form for the job specification.
    Type: Grant
    Filed: May 1, 2008
    Date of Patent: February 14, 2012
    Assignee: My Perfect Gig, Inc.
    Inventor: Mark Dane
  • Patent number: 8117492
    Abstract: Techniques for backup error management are disclosed. In one particular exemplary embodiment, the techniques may be realized as a method for backup error management comprising receiving a backup job error from a backup job, providing an error indicator and at least one user selectable option, receiving a user input corresponding to the at least one user selectable option, and modifying a backup policy to address the error based at least in part on the received user input.
    Type: Grant
    Filed: January 29, 2010
    Date of Patent: February 14, 2012
    Assignee: Symantec Corporation
    Inventors: Kirk Searls, Gregory Robert Dowers, II
  • Patent number: 8117487
    Abstract: A method and apparatus for proactively monitoring data center health data to achieve workload management and high availability is provided. In one embodiment, a method for processing application health data to improve application performance within a cluster includes accessing at least one of performance data or event information associated with at least one application to determine application health data and examining the application health data to identify an application of the at least one application to migrate.
    Type: Grant
    Filed: December 29, 2008
    Date of Patent: February 14, 2012
    Assignee: Symantec Corporation
    Inventors: Yojana Narharrao Raut, Rakesh Kumar Agrawal, Mehendra Dilip Karmuse
  • Patent number: 8112454
    Abstract: A method of segmenting relative user preferences into fine-grain and coarse-grain collections is provided. The method includes providing a set of content items having associated descriptive terms. The method also includes receiving user search input and, in response thereto, presenting a subset of content items. The method includes receiving user selection actions and analyzing the selections to learn the user's preferred descriptive terms. The method includes expressing the learned preferred descriptive terms as a segmented probability distribution function having at least one fine grain segment and at least one coarse grain segment. In response to subsequent search input, the method calls for selecting and ordering a collection of content items by promoting the ranking of content items associated with the learned preferred descriptive terms of the user according to the differentiation provided by the segmented probability distribution function.
    Type: Grant
    Filed: May 5, 2009
    Date of Patent: February 7, 2012
    Assignee: Veveo, Inc.
    Inventors: Murali Aravamudan, Ajit Rajasekharan, Kajamalai G. Ramakrishnan, Mayank Gupta
  • Patent number: 8110668
    Abstract: Nucleic acid and protein sequences relating to a cation channel which is sperm-specific (CatSper3) are disclosed. The CatSper3 protein is shown to be specifically expressed in sperm. Nucleic acids, vectors, transformed cells, transgenic animals, polypeptides, and antibodies relating to the CatSper3 gene and protein are disclosed. Also provided are methods of in vitro fertilization and contraception, methods of identifying modulators of CatSper3 activity, methods of genotyping subjects with respect to CatSper3, and methods of diagnosing and treating CatSper3-mediated disorders, including infertility. Related business methods are also disclosed.
    Type: Grant
    Filed: August 4, 2003
    Date of Patent: February 7, 2012
    Assignee: Children's Medical Center Corporation
    Inventors: Magdalene M. Moran, Jayhong A. Chong, Ian Scott Ramsey, David E. Clapham
  • Patent number: 8112742
    Abstract: A method and system for debugging data integration applications with reusable synthetic data values. The method includes receiving a specification for a data integration application comprising transformation rules, receiving synthetic data values to use as test values for the inputs of the transformation rules, and using the synthetic data values for testing the functionality of the transformation rules.
    Type: Grant
    Filed: July 22, 2008
    Date of Patent: February 7, 2012
    Assignee: Expressor Software
    Inventor: John Russell