Abstract: The present invention generally relates to a series of compounds, to pharmaceutical compositions containing the compounds, and to use of the compounds and compositions as therapeutic agents. More specifically, compounds of the present invention are tricyclic indeno-pyrrole compounds. These compounds are serotonin receptor (5-HT) ligands and are useful for treating diseases, disorders, and conditions wherein modulation of the activity of serotonin receptors (5-HT) is desired (e.g. anxiety, depression and obesity).

Abstract: A stamp marker capable of adhering an application liquid to a target. The stamp marker includes a liquid-permeating member and a container containing an application liquid, the liquid-permeating member including a distal member, a base, and a fixing member. The distal member has a surface having a contacting part and a noncontacting part, the contacting part having a shape, so as to copy the shape onto the target by bringing the surface of the distal member into contact with the target to make the liquid adhere to the target, so that an adhesion mark of a predetermined shape is formed on the target.

Abstract: A vapor compression distillation system (10) is provided and includes a fluid inlet (12) for receiving a fluid, a fluid outlet (14) for a distillate that has been distilled from the fluid, a heat exchanger (16) connected to the fluid inlet (12) and the fluid outlet (14) to transfer heat from the distillate to the fluid; and an integrated motor/compressor unit (18) connected to the heat exchanger (16) to receive vaporized distillate therefrom and to supply pressurized distillate thereto. The system 10 may further include a coolant system (20) connected to the integrated motor/compressor (18) to supply a coolant flow thereto. The system (10) may also include an air oil mist system (22) that is connected to the integrated motor/compressor unit (18) to supply an air oil mist thereto for bearing lubrication and cooling.

Abstract: This invention concerns a web-based system comprising a server, computer storage and web-portal to provide an integrated management feedback system for the assessment of educational services. The system particularly comprises an interface to input definitions of graduate attributes related to levels of complexity; and input definitions of learning outcomes related to teaching theory which defines levels for outcomes. A database to map relationships between graduate attributes at particular levels of complexity and their related teaching methods and assessment items; and learning outcomes at particular levels and their related teaching methods and assessment items. A processor to automatically respond to the assessment results for a particular student and determine and record both the graduate attribute levels of complexity, and learning outcomes levels, achieved by that student.

Abstract: A tablet filling instrument 1 for dispensing tablets into a vial 9 in accordance with prescription data and discharging the vial 9 filled with the tablets in one of a plurality of outlets 113 designates at least one of the outlets 113 to be a priority outlet 113p and discharges the vial 9 filled with the tablets in the priority outlet 113p when the tablets are to be dispensed in one of the outlets 113 at a time-point within a predetermined time length from a present time-point.

Abstract: A tip unit (1) incorporated in a liquid applicator such as a ball-point pen, the tip unit being capable of an increased rate of liquid discharge with no leaking or clogging problem. To achieve it, the tip unit (1) is accommodated in a tip body (11) having a ball housing (15), a ball (10), a capillary hole (16), and a proximal bore, the ball housing (15) being a passage for allowing liquid to flow therethrough, the ball (10) being rotatively held in the ball housing (15). The ball housing (15) is provided with at least one ink channel (47) adapted to communicate the ball housing (15) with the capillary hole (16) or the proximal bore. The ball housing (15) has a ball resting seat (45) and a side wall (41) that are connected by a connecting surface (71) having a shape of a truncated conical surface with its apex toward the distal end of the tip unit (1).

Abstract: A packaging system in which an object can be maintained for shipping. The packaging system has a shell defining a space for reception of an object in a shipping state and an object engaging surface assembly that bounds at least a part of the space. The packaging system further has a fluid chamber assembly and a fluid within the fluid chamber assembly that has a variable pressure that is increased, thereby to cause the object engaging surface assembly to resiliently bear with increasing force against an object in the shipping state. The fluid within the fluid chamber assembly remains in a flowable state with the packaging system in a final state for shipping.

Abstract: A component for a vehicular exhaust pipe includes an upstream venturi forming portion for creating at least a partial vacuum interior to the component. A downstream diverter housing portion of the component has an inlet coupled to an outlet of the venturi portion. The diverter housing portion includes the diverter element positioned adjacent an output of the diverter housing portion for forcing axially central exhaust flow radially outward toward a wall of the diverter housing. The partial vacuum in the component device causes colder environmental ambient air to enter an inlet of the component. The diverter also creates a mixture of hot exhaust flow with the colder environmental air, resulting in a lower temperature of the exhaust gas exiting the component and substantial elimination of centrally disposed exhaust hot spots.

Abstract: This invention concerns interfacing to electronic circuits or systems operating at low temperature or ultra-low temperature using complementary metal-oxide semiconductor (CMOS) technology. Low temperature in this case refers to cryogenic temperatures in particular, but not exclusively, to the 4.2 K region. Ultra-low temperatures here refers to the sub-1 K range, usually accessed using dilution refrigerator systems. The electronic circuits comprise a controller (for writing and manipulation), an observer (for readout and measurement) circuits, or both, fabricated from ultra-thin silicon-on-insulator (SOI) CMOS technology.

Abstract: New vitamin D derivative compounds containing a monohalovinyl moiety at position C-20 are described. A process for obtaining the new compounds, consisting of reacting an aldehyde precursor with a haloform in the presence of Cr2+ salts, is also described.

Abstract: Soluble and stable liquid compositions containing a plant growth regulator selected from the group consisting of cytokinin and a gibberellin, an acid solubilizer such as citric acid, tartaric acid or glycolic acid and a solvent; as well as methods for making and using the composition are disclosed. The compositions improve solubility, handling, stability, safety, as well as activity improvements such as improved plant growth, yield, fruit thinning or sizing and quality. The compositions are soluble and stable by adding an ethoxylated alkyl alcohol wherein the growth regulator is 6-benzyladenine (6-BA) or forchlorfenuron (CPPU) and the ethoxylated alcohol surfactant is C12-15 alkyl alcohol in propylene glycol. The compositions may also contain a cytokinin such as 6-benzyladenine (6-BA) or forchlorfenuron (CPPU) that is increased in solubility and activity and by synergistically combined with GA3 or GA4A7 as well as in storage stability by adding an antioxidant.

Abstract: A powered conduit bending tool comprises a portable drive housing including a handle and having a powered drive gear. A bracket is secured to the housing defining a pivot connection spaced from the drive gear. A guide is operatively secured to the housing. A platform is pivotally connected to the bracket at the pivot connection and includes a driven gear operatively engaging the drive gear to controllably pivot the platform. A shoe is removably mountable to the platform and comprises a first bender defining a downwardly opening arcuate channel selectively positionable proximate the guide. A hook is proximate one end of the bender for engaging a conduit received in the channel. In use, the guide supports a conduit engaged by the hook and pivotal movement of the shoe driven by the platform deforms the conduit as it passes by the guide.

Abstract: This invention relates to compounds of the formulas (1), (2) and (3) having pharmacological activity, to compositions containing these compounds, and to methods of treatment employing the compounds and compositions.

Abstract: The present invention generally relates to a series of compounds, to pharmaceutical compositions containing the compounds, and to use of the compounds and compositions as therapeutic agents. More specifically, compounds of the present invention are thiophenyl and pyrrolyl azepine compounds. These compounds are serotonin receptor (5-HT2c) ligands and are useful for treating diseases, disorders, and conditions wherein modulation of the activity of serotonin receptors (5-HT2c) is desired (e.g. addiction, anxiety, depression, obesity, and others).

Abstract: Disclosed are improved methods for the synthesis of phospholipid ether analogs and alkyl phosphocholine analogs. The methods allow greater versatility of the reactants used and greater ease in synthesizing alkyl chains of varying length while affording reaction temperatures at room temperature or below. The methods disclosed herein provide reactants and conditions using alkyl halides and organozinc reagents and do not utilize Gringard reactions thus, allowing greater ease of their separation and purity of products. The PLE compounds synthesized by the methods disclosed herein can also be used for synthesizing high specific activity phospholipid ether (PLE) analogs, for use in treatment and diagnosis of cancer.

Abstract: A protective garment of a type preferably conforming to at least one NFPA standard and worn by firefighters and by emergency rescue workers has a body, which has two sleeve mouths, and has two sleeves. Each sleeve is attached to the body by being sewn thereto, along and around a margin of an associated one of the sleeve mouths, so as to extend in a forward direction when unstressed. The forward direction may be a forward and downward direction, a forward and upward direction, or a forward and lateral direction. The protective garment may be a protective coat, a protective jacket, a protective shirt, or a suit of protective coveralls.

Abstract: A method of treating bio waste including the steps of (1) fermenting substantially raw biowaste in a pathogen reduction stage under anaerobic conditions for a predetermined period at a temperature in the mesophillic temperature range and (2) subsequently separating the solid and liquid phases to produce a fermented cake and fermented liquor. The fermented cake has at least 15% solids on dry basis and contains over 500 mg/L ammonia, over 1,000 mg/L total Volatile Fatty Acids (tVFA) and Escherichia coli less than 100,000 cfu per g dry solids. The fermented liquor contains over 10,000 mg/L COD, over 500 mg/L ammonia, over 1,000 mg/L tVFA and less than 5,000 mg/L of suspended solids.

Abstract: A through air level measurement instrument for use in minimizing tank rattle comprises a housing and an antenna secured to the housing. A process adaptor is associated with the antenna and the housing for securing the instrument to a closed tank with the antenna directed into an interior of the closed tank. A control in the housing generates and receives a high frequency signal using an electromagnetic radiating element proximate the antenna. The control comprises an equivalent time sampling circuit including a main oscillator driving a timing circuit controlling timing between transmitted and sample pulses. A noise generator is operatively associated with the main oscillator to randomly modulate timing of the main oscillator. The control minimizes inaccuracies caused by tank rattle.