Abstract: The present invention concerns devices and methods for controlling actin filaments growth and organization with micro patterned nucleation sites, their uses for studying actin network formation, for screening of drugs or for preparing complex structures.

Abstract: The present invention pertains to method for purifying at least a target nucleic acid from a sample, said method comprising at least the following steps: a) incubating the sample with at least one protein-degrading compound; b) binding the target nucleic acid to a solid phase; c) eluting the target nucleic acid from the solid phase; d) incubating the eluted target nucleic acid with at least one protein-degrading compound; e) binding the target nucleic acid again to a solid phase; f) optionally eluting the bound target nucleic acid from the solid phase. It was surprisingly found that performing a second protein digestion step after the target nucleic acid was bound and eluted from a solid phase before the nucleic acids are rebound to a solid phase is very efficient in reducing remaining protein contaminations in the isolated nucleic acid.

Abstract: The invention relates to a composition for injectable cement, comprising a mineral sold phase, a separate liquid phase and, optionally, microparticles of a biocompatible and biodegradable polymer. The mineral solid phase comprises a mixture of powders with the molar composition: (CP)6 (CaO)y (SrCO3)z, [CP being CaHPO42H2O, CaHPO4, Ca1-xSrxHPO4, an equimolar mixture of bis(Ca(H2PO4)2, H2O and CaO, or a mixture of two or three of said compounds] and y+z=4?1. The liquid phase comprises pure apyrogeneic water or a saline aqueous solution with pH 4 to 9. The ratio L/P [volume of liquid phase/mass of solid mineral phase] is at least 0.4 ml/g. The above is of application as bone replacement.

Abstract: The subject matter of the invention is a process for synthesizing a saturated long-chain o.,0)-amino ester (acid) obtained in a first step by cross-metathesis between an acrylic first compound and a monounsaturated second compound comprising at least one nitrile, acid or ester trivalent function, one of these compounds comprising a nitrile function and the other an acid or ester function, in the presence of a ruthenium carbene metathesis catalyst, and in a second step by hydrogenation of the monounsaturated nitrile ester (acid) obtained in the presence of the metathesis catalyst of the preceding stop, acting as a hydrogenation catalyst.

Abstract: Modified influenza A/PR/8/34 virus and reassortant influenza A/PR/8/34 virus including a modified PB1 gene and methods for improving the production of HA (hemagglutinin) and NA (neuraminidase) vaccine glycoproteins.

Abstract: The present invention relates to a recombinant vector for expressing and secreting, by a propionibacterium, one or more amino acid sequences of interest, wherein said vector comprises at least: under the control of at least one suitable promoter, at least one nucleotide sequence coding for a propionibacteria signal peptide and, in translational fusion with said nucleotide sequence, one or more nucleotide sequences coding for said amino acid sequence or sequences of interest. The invention further relates to the uses of such a vector in the pharmaceutical field or for the large-scale production of peptides or proteins of interest.

Abstract: At least one compound of following formula I: in which: X is C or N, Y is CH3 or OH, and Z is H or CH3, or one of its pharmaceutically acceptable salts, hydrates, esters or isomers, for use in the manufacture of a medicament to treat pathologies in which an imbalance between cell division and apoptosis is involved.

Abstract: The present invention relates to the use of the assessment of the binding between—antibodies elicited against a first glycoprotein, and—at least one glycoform of a second glycoprotein, said second glycoprotein being itself a glycoform of the first protein, wherein said glycoform of the second glycoprotein is selected from a group of glycoforms of the second glycoprotein, each glycoform of said group corresponding to a determined glycosylation state defined by a determined sialylation state, and/or a determined branching state, and/or a determined fucosylation state, provided that said glycosylation state is not uniquely defined by a substantially unsialylated state, for the screening of glycoform specific antibodies directed against a given glycoform of the second glycoprotein.

Abstract: A system for collecting an anaesthetic agent, having at least one anaesthetic gas scavenging system (AGSS) for receiving exhaust gas from a plurality of sources, the exhaust gas including the anaesthetic agent to be collected, each AGSS comprising at least one power source for providing suction of the exhaust gas from the plurality of sources under negative pressure, and a central collection system for receiving the exhaust gas, the central collection system comprising at least one collector for collecting the anaesthetic agent from the exhaust gas, wherein the at least one collector is configured to adsorb the anaesthetic agent from the exhaust gas. The central collection system may be configured to received the exhaust gases from the at least one AGSS, with the central collection system being located downstream of the at least one AGSS.

Abstract: The invention relates to a fibre sensor that enables the propagation of infrared light at at least one wavelength of 0.8 to 25 micrometres, the fibre successively comprising along its length a first infrared waveguide section (23), a second detection section (25) intended to come into contact with an external environment in order to detect infrared signatures interfering with the propagation of the evanescent waves propagating along the fibre (2), and a third infrared waveguide section (27). The invention is characterized in that, in the second fibre section (25) that has the detection role, the fibre (2) is constituted of a curved part, the radios of curvature of which is locally less than 2.3 millimetres.

Abstract: A trim tab assembly for a watercraft includes a enclosure. A support structure is positioned in the enclosure. At least one trim tab is disposed in the enclosure. The trim tab includes a generally planar top, bottom, side and front surfaces linked by a curved surface defining a wedge shaped body. An actuator is linked to the trim tab pivotally moving the trim tab relative to the enclosure.

Abstract: The present invention relates to new intermetallic compounds having a crystalline structure of Ni3Sn2 type for the magnetic refrigeration, their use and a process for preparing the same. The present invention further relates to new magnetocaloric compositions for the magnetic refrigeration and their use.

Abstract: This invention discloses a composition of thermoplastic based electronic conductive inks, more specifically electronic conductive inks containing chemically functioned thermoplastic resins and poly(3,4-ethylenedioxythiophene). This invention also teaches the method of making the same and electronic devices making from the same.

Abstract: A planetary rotary type rotation device comprises a stator, a rotor, and a center sun wheel drum (10). The stator includes a hollow cylinder block (1) having a cylinder. The rotor includes a main shaft (3), planetary piston wheel fixation flanges (9), and a planetary piston wheel (8). The two planetary piston wheel fixation flanges (9) are symmetrically fixed to the main shaft (3). The center sun wheel drum (10) is disposed between the two planetary piston wheel fixation flanges (9) and fitted over the main shaft (3). An annular piston space (19) is formed between an outer circular surface of the center sun wheel drum (10) and a cylinder wall of the cylinder of the cylinder block (1). The planetary piston wheel (8) is a cylindrical roller. The cylindrical roller is disposed in the annular piston space (19) in a rolling manner. Both ends of the cylindrical roller are fixed to the planetary piston wheel fixation flanges (9).

Abstract: Polynucleotides useful for detecting copy number variation of RNU2 sequences and methods of assessing risk of developing breast or ovarian cancer using molecular combing and/or detection or quantification of BRCA1 expression.

Abstract: A method of generating electrical energy in an integrated circuit that may include setting into motion a (3D) three-dimensional enclosed space in the integrated circuit. The 3D enclosed space may include a piezoelectric element and a free moving object therein. The method may also include producing the electrical energy from impact between the free moving object and the piezoelectric element during the motion.

Abstract: An electronic device, and a power supplying method and a wireless power supplying system thereof. The electronic device includes a wired electric power receiving module, a wireless electric power receiving module and a switch. The wired electric power receiving module is connected to an external power supply by wired transmission. The wireless electric power receiving module receives the wireless electric power from an external wireless electric power transmitting device. The switch is coupled to the wired electric power receiving module and the wireless electric power receiving module and is used to switch between the wired electric power receiving module and the wireless electric power receiving module, to supply the operating voltage. The electronic device can operate in the wireless power supplying mode or the wired power supplying mode, so as to facilitate a user to use.

Abstract: The present invention relates to a series of novel imidazo[1,2-?]pyrrolo[3,2-c]pyridines (or also named 6H-1,3a,6-Tri-aza-?y-indacenes) and derivatives thereof, according to formula: (I); The present invention also relates to processes for the preparation of imidazo[1,2-?]pyrrolo[3,2-c]pyridines, their use as. a, medicine, their use to treat or prevent viral infections and their use to manufacture a medicine to treat or prevent viral infections, particularly infections with viruses belonging to the family of the Flaviviridae and more preferably infections with Bovine Viral Diarrhea virus (BVDV).

Abstract: A system and method for providing a view of a virtual space to a user in a banner ad of a webpage. This enables an advertiser to provide content that is not merely static or scripted, but instead enabled provision of content through a web ad that represents activity within a virtual space (e.g., interactions of other users with the virtual space, content that changes based on current or recent events, etc.) in real time (or near real time). The provision of a virtual space in a web ad may be more effective than conventional web ad content.

Abstract: The invention relates to compounds of formula (I) wherein the groups A and B represent independently from each other —CH?CH—, or —C?C—, the terms t, u, v, w represent, independently from each other, values ranging from 0 to 9, the groups Y1 and Y2 can represent independently from each other an alkyl group (linear, branched or substituted) carrying from 1 to 9 carbon atoms, the groups Z1, Z2, Z3, and Z4 can represent independently from each other a chemically reactive group W, such as OH, NH2, SH, the groups Z5 and Z6 represent independently from each other a hydrogen atom, silica nanoparticles functionalized by these compounds, and their use as drugs.