Patents Assigned to 1
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Publication number: 20250111949Abstract: A computer system and computer implemented method for determining a risk level of a candidate patient for developing Alzheimer's disease are provided. Laboratory test results from a laboratory are received at a computing device having one or more processors. The laboratory test results correspond to the candidate patient. Prescription date indicative of medications taken by the candidate patient are received at the computing device. Diagnosis data indicative of medical diagnoses associated with the candidate patient are received at the computing device. Age and gender associated with the candidate patient are received at the computing device. Features of the laboratory test results are preprocessed into categories. An Alzheimer's risk score associated with the candidate patient is generated by the computing device utilizing at least one machine learning model based on the prescription data, diagnosis data, age, gender and categorized features. The Alzheimer's risk score is output by the computing device.Type: ApplicationFiled: October 1, 2024Publication date: April 3, 2025Applicant: HC1 Insight LLCInventors: Bradley A. Bostic, Charles J. Clarke, William E. Robinson, Charles Girard, JR.
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Publication number: 20250110453Abstract: Disclosed are systems and methods that provide a novel framework for personalized location management and control via integrated large language model (LLM) capabilities within the location's control system(s). The framework operates to predict certain events within and/or around a location, and maximize the capabilities of an implemented control system to leverage such predictions via mechanisms to understand the current and/or future needs of a user(s) within such location. Such mechanisms can involve the implementation of AI, ML and/or LLMs, such that predicted events as well as currently detected data related to current and/or ongoing events can be fed to the disclosed framework, whereby adaptive, personalized and/or customized responses can be output.Type: ApplicationFiled: September 27, 2024Publication date: April 3, 2025Applicant: ADEMCO 1 LTDInventor: Robert John Probin
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Patent number: 12265864Abstract: The information code has an information code area constituted of colored information cells with two or more colors, the information code area having the specific information recorded using the information cells as information units, and a teacher code area having teacher cells with the same colors and the same number of colors as the information cells so as to identify the colors of the information cells. In the information code, the teacher code area is placed away from the information code area or inside the information code area.Type: GrantFiled: January 10, 2024Date of Patent: April 1, 2025Assignee: VARIETY M-1 INC.Inventor: Toshiaki Mitake
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Publication number: 20250104056Abstract: A payment management system including a payment management unit that initiates a transaction, an operation unit that manages the issuance of at least one certificate, a governance unit that operates based on at least one parameter defined in the at least one certificate; at least one validation unit that receives the at least one certificate and validates portions of the transaction; and a payment unit that issues payment based on the terms of the at least one certificate, where the operation unit crates a governance protocol for each transaction with the governance protocol including at least one epoch and at least one checkpoint.Type: ApplicationFiled: September 19, 2024Publication date: March 27, 2025Applicant: 1Money Co.Inventors: Christoph Siebenbrunner, Laurent Bindschaedler
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Patent number: 12258748Abstract: Building techniques and structures to fabricate components of expanded polystyrene (EPS) for assembly into a building include structures and ways to make keys to provide shear strength between components, structures and ways to minimize infiltration paths between walls and floors and walls and roof while reducing labor, material wastage and logistics complications. By way of example, components are strategically cut from a block of EPS using a hot wire moving through the block to cut components to a desired and novel configuration.Type: GrantFiled: August 30, 2022Date of Patent: March 25, 2025Assignee: Global 1 Habitats, LLCInventors: Gordon R. McGilton, Larry E. Elliott
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Patent number: 12256754Abstract: Provided is a composition that is solid at 23° C. comprising, by weight based on the weight of the composition, (a) 0.4% to 12% one or more ethylcellulose polymers; (b) 0.5% to 8% stearic acid; (c) 15% to 90% one or more unsaturated oils; and (d) 6% to 70% one or more saturated fats. Also provided is a method of making a baked pastry composition comprising vertically compressing a structure (i) comprising a horizontal top layer, a horizontal intermediate layer, and a horizontal bottom layer, to reduce the thickness of the structure and produce a compressed structure (ii), wherein the top layer comprises dough, the intermediate layer comprises the above composition, and the bottom layer comprises dough. Also provided is a pastry composition comprising, by weight based on the weight of the pastry composition, ethylcellulose polymer, stearic acid, unsaturated oil, flour, and water.Type: GrantFiled: September 14, 2017Date of Patent: March 25, 2025Assignee: NUTRITION & BIOSCIENCES USA 1, LLCInventors: Roja Ergun, Asim Syed, Anne Adden
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Patent number: 12261997Abstract: There is provided a technique including: a merging candidate constructor structured to construct a merging candidate list including merging candidates having a maximum number of merging candidates including spatial merging candidates; a normal merging candidate selector structured to select a normal merging candidate that is uni-prediction or bi-prediction from the merging candidate list based on a merge index; and a triangle merging candidate selector structured to select a first triangle merging candidate that is uni-prediction from the merging candidate list based on a first triangle merge index and select a second triangle merging candidate that is uni-prediction based on a second triangle merge index, in which a first maximum number of triangle merging candidates regarding the first triangle merge index is the same as the maximum number of merging candidates.Type: GrantFiled: September 8, 2021Date of Patent: March 25, 2025Assignee: Godo Kaisha IP Bridge1Inventors: Hideki Takehara, Hiroya Nakamura, Satoru Sakazume, Shigeru Fukushima, Toru Kumakura, Hiroyuki Kurashige
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Patent number: 12257428Abstract: A wireless power transfer system is provided. The system includes an external transmit resonator and an implantable receive resonator. The transmit resonator is configured to transmit wireless power, wherein the external transmit resonator includes one of i) one or more loops of Litz wire and ii) a plurality of stacked plates. The implantable receive resonator is configured to receive the transmitted wireless power from the external transmit resonator, wherein the implantable receive resonator is configured to power a ventricular assist device (VAD) implanted in a subject using the received wireless power. The implantable receive resonator includes the other of i) the one or more loops of Litz wire and ii) the plurality of stacked plates.Type: GrantFiled: March 10, 2021Date of Patent: March 25, 2025Assignee: TC1 LLCInventors: John Freddy Hansen, Eric Lee
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Patent number: 12257227Abstract: The use of a pharmaceutical composition in treating cancer in a subject comprising a therapeutically effective amount of a compound of formula (I), a therapeutically effective amount of paclitaxel and a low dose of gemcitabine, and a kit included above composition thereof.Type: GrantFiled: October 12, 2019Date of Patent: March 25, 2025Assignee: 1GLOBE BIOMEDICAL CO., LTD.Inventor: Chiang J. Li
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Publication number: 20250090835Abstract: Blood circulation assist systems include a ventricular assist device (VAD), a remote accelerometer, and a controller that controls operation of the VAD based on output of the remote accelerometer. A blood circulation assist system includes a VAD, a controller, and a remote accelerometer. The VAD includes an impeller. The remote accelerometer is configured to generate a remote accelerometer output indicative of accelerations measured by the remote accelerometer. The implanted controller controls a rotation speed of the impeller based on the remote accelerometer output.Type: ApplicationFiled: November 25, 2024Publication date: March 20, 2025Applicant: TC1 LLCInventors: Daniel I. Harjes, Russell Anderson, Pritika Toutam, Brian Kimball
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Patent number: 12255066Abstract: A method for producing nanostructures having a metal oxide shell, carried by a top face of a substrate whose greatest dimension is greater than or equal to 100 mm by MOCVD metalorganic chemical vapour deposition, including successive steps carried out in a reactor configured for MOCVD deposition of nucleation and growth. The nucleation step includes forming non-contiguous metal nuclei by depositing a metal by MOCVD using a metalorganic precursor on the top face of the substrate and oxidising the metal of the metal nuclei, to form oxidised nuclei and ensure stabilisation of the nuclei. The growth step includes depositing a metal by MOCVD using the metalorganic precursor, to form non-contiguous nanostructures by growth of the oxidised nanostructures, and oxidising the deposited metal of the nanostructures formed in the nucleation to form oxidised nanostructures.Type: GrantFiled: November 26, 2020Date of Patent: March 18, 2025Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE GRENOBLE ALPES, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON, UNIVERSITE CLAUDE BERNARD LYON 1, ECOLE CENTRALE DE LYON, ECOLE SUPERIEURE CHIMIE PHYSIQUE ELECTRONIQUE LYONInventors: Pierre-Vincent Guenery, Thierry Baron, Jeremy Moeyaert
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Publication number: 20250087610Abstract: An electronic chip including a support and connection pillars, each connection pillar including a trunk including an end portion and an intermediate portion coupling the end portion to the support, and including a collar at the junction between the end portion and the intermediate portion.Type: ApplicationFiled: September 5, 2024Publication date: March 13, 2025Applicants: Commissariat à I'Énergie Atomique et aux Énergies Alternatives, Centre National de la Recherche Scientifique, Université de Bordeaux 1, Institut Polytechnique de BordeauxInventors: Céline Feautrier, Jean-Charles Souriau, Julie Gougeon, Mona Treguer-Delapierre
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Patent number: 12246953Abstract: A large-scale tool hoisting device for offshore electric power construction is provided. A steel cable retracted to winches is dried using the heat in the operating cabin, thereby preventing the steel cable from being in a wet state for a long time and being corroded by seawater. For different loads at the terminal of the steel cable, a transmission ratio between a drive wheel and a control wheel is changed through the sliding of the drive wheel. Without changing the rotational speed of the drive motor, the moving speed of the steel cable is effectively and correspondingly improved by reducing the pulling force of the steel cable, or a large pulling force can be provided for the steel cable by reducing the moving speed of the steel cable. The transmission ratio can be changed in the hoisting process.Type: GrantFiled: October 30, 2024Date of Patent: March 11, 2025Assignee: POWERCHINA SEPCO1 ELECTRIC POWER CONSTRUCTION CO., LTD.Inventors: Jiyong Pang, Jianping Zhang, Guodong Shao
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Patent number: 12247901Abstract: A soil layer detection drilling device includes a drilling cylinder, and a soil-sampling assembly is provided inside the drilling cylinder. When the soil is drilled, equipment is in a vertical state, a controller is turned on to control a rotary motor to rotate, and the drilling cylinder is driven to drill the soil with the cooperation of drive wheels and a drive belt. Four slide blocks are evenly distributed around an outer circumference of a sliding disk and are matingly connected with slide grooves provided on an inner wall of the drilling cylinder, so when the drilling cylinder rotates, the soil-sampling assembly also rotates. A conical head first in contact with the ground starts to drill the ground, then the drilling cylinder gradually drills into a soil layer, and the drilling cylinder is idled as the drilling cylinder arrives at a certain depth, to clear soil on auger blades.Type: GrantFiled: November 12, 2024Date of Patent: March 11, 2025Assignee: POWERCHINA SEPCO1 ELECTRIC POWER CONSTRUCION CO., LTD.Inventors: Chuanguo Du, Jiyong Pang, Gaojun Qi, Di Tang, Tao Chen
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Patent number: 12249056Abstract: A vehicle surface analysis system includes a vehicle positioning unit, an optical image acquisition unit and an evaluation unit. The vehicle positioning unit includes a rotatable platform for supporting a vehicle. The image acquisition unit includes a plurality of individual image acquisition units, which operate with different wavelength work spectra and radiation energy levels to generate a number of recorded mages. The evaluation unit includes a difference value generation module, a difference value assessment module, an overall assessment module, and a generation module. The evaluation unit is constructed to provide a digital surface condition image of the vehicle.Type: GrantFiled: July 29, 2021Date of Patent: March 11, 2025Assignee: AUTO1 Group SEInventors: Jozsef Bugovics, Dudasz Zsolt, Hans Schlüter
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Patent number: 12249326Abstract: At least one exemplary embodiment is directed to a method and device for voice operated control with learning. The method can include measuring a first sound received from a first microphone, measuring a second sound received from a second microphone, detecting a spoken voice based on an analysis of measurements taken at the first and second microphone, learning from the analysis when the user is speaking and a speaking level in noisy environments, training a decision unit from the learning to be robust to a detection of the spoken voice in the noisy environments, mixing the first sound and the second sound to produce a mixed signal, and controlling the production of the mixed signal based on the learning of one or more aspects of the spoken voice and ambient sounds in the noisy environments.Type: GrantFiled: September 23, 2021Date of Patent: March 11, 2025Assignee: ST Case1Tech, LLCInventors: John Usher, Steven Goldstein, Marc Boillot
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Patent number: 12247062Abstract: Novel synthetic biology-based ADCC technologies are provided that enhance or enable ADCC responses, for example, through a rationally-designed soluble universal ADCC enhancer protein (SUAEP) where a high-affinity CD3-binding domain is fused to a high-affinity Fc-binding domain. The SUAEP technology can be used to prevent or treat cancers, infectious, inflammatory or autoimmune diseases, and other diseases where elimination of diseased cells is desirable.Type: GrantFiled: December 8, 2015Date of Patent: March 11, 2025Assignee: 1GLOBE BIOMEDICAL CO., LTD.Inventors: Chiang J. Li, Shyam Unniraman
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Publication number: 20250074769Abstract: Hydrogen generation assemblies and methods are disclosed. In one embodiment, the method includes receiving a feed stream in a fuel processing assembly, and heating, via one or more burners, a hydrogen generating region of the fuel processing assembly to at least a minimum hydrogen-producing temperature. The method additionally includes generating an output stream in the heated hydrogen generating region of the fuel processing assembly from the received feed stream, and generating a product hydrogen stream and a byproduct stream in a purification region of the fuel processing assembly from the output stream. The method further includes separating at least a portion of the carbon dioxide gas from the byproduct stream to generate a fuel stream having a carbon dioxide concentration less than the byproduct stream, and feeding the fuel stream to the one or more burners.Type: ApplicationFiled: November 21, 2024Publication date: March 6, 2025Applicant: Element 1 CorpInventor: David J Edlund
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Publication number: 20250075247Abstract: The present invention relates to a method for determining the methicillin-resistance properties of a Staphylococcus aureus strain present in a biological sample, the method comprising the following steps: •a) incubating the biological sample containing the Staphylococcus aureus strain for at least 15 minutes in the presence of an antibiotic from the class of beta-lactams selected from the following group: cefoxitin and 6-APA (6-aminopenicillanic acid); •b) isolating the bacteria present in the biological sample; •c) lysing the bacteria and hydrolysing the bacterial proteins in order to obtain a mixture of peptides; and •d) analysing this mixture of peptides by targeted mass spectrometry, the detection of at least one peptide originating from the protein PBP2a (SEQ ID NO. 1) or PBP2c (SEQ ID NO. 2) during this analysis step being indicative of the methicillin resistance of the Staphylococcus aureus strain present in the biological sample.Type: ApplicationFiled: January 11, 2023Publication date: March 6, 2025Applicants: UNIVERSITE CLAUDE BERNARD LYON 1, ECOLE NORMALE SUPERIEURE DE LYON, HOSPICES CIVILS DE LYON, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSERM (Institut National de la Santé et de la Recherche Médicale), WEEZIONInventors: Jérôme LEMOINE, Francis DEFORET, François VANDENESCH, Olivier DAUWALDER
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Patent number: 12244147Abstract: A renewable power system with a twin-configurable architecture is described. The system includes a renewable energy source (RES), an energy storage system (ESS), and at least one controllable load (CL) (e.g., AI training/datacenter). The system can serve as a baseload or semi-baseload plant for CL(s) and/or as a peaker or semi-peaker plant for an electric grid, or vice-versa, and optionally in parallel, can also provide ancillary services to the electric grid and/or to the CL(s). In certain embodiments, e.g. solar PV RES(es), the system can have capacity factors of at least about 60% and up to 100%, higher asset utilization, better economics for the RES-ESS, improved system performance, and lower energy costs as compared with known systems without a CL(s). By making load a variable, and integral part of the system, sophisticated resource allocation strategies, including AI algorithms, can be developed not previously possible with known systems lacking a CL(s).Type: GrantFiled: August 2, 2024Date of Patent: March 4, 2025Assignee: 1st Avenue Nova, LLCInventor: Thomas Buttgenbach