Abstract: Described is a system, method and apparatus for measuring a vibrational response in an eye for determination of ocular parameters such as intraocular pressure, corneal elasticity and scleral pressure. The method comprises positioning an air jet nozzle to direct an excitation stimulus at a single frequency to the apex of the eye along the optical axis of the eye; positioning a sensor to direct incident light at a fixed position of the eye distinct from the apex of the eye; exciting vibration in the eye with the excitation stimulus; directing incident light from the sensor to the fixed position of the eye; and detecting backscatter light from the eye with the sensor, to measure the vibrational response. Algorithms are used to calculate the ocular pressure from the vibrational response of the cornea or sclera. The method does not require contact with the eye, and is reliable and accurate.

Abstract: A novel and useful modified semiconductor fabrication technique for realizing reliable semiconductor quantum structures. Quantum structures require a minimization of the parasitic capacitance of the control gate and the quantum well. The modified semiconductor process eliminates the fabrication of the metal, contact, and optionally the raised diffusion layers from the quantum wells, thereby resulting in much lower well and gate capacitances and therefore larger Coulomb blockade voltages. This allows easier implementation of the electronic control circuits in that they can have larger intrinsic noise and relaxed analog resolution. Several processes are disclosed including implementations of semiconductor quantum structures with tunneling through an oxide layer as well as tunneling through a local well depleted region. These techniques can be used in both planar semiconductor processes and 3D, e.g., FinFET, semiconductor processes. A dedicated process masking step is used for realizing the raised diffusions.

Abstract: Systems and method for powering an implanted blood pump are disclosed herein. The system can be a mechanical circulatory support system. The mechanical circulatory support system can include an implantable blood pump. The implantable blood pump includes a DC powered pump control unit that can control the blood pump according to one or several stored instructions. The implantable blood pump includes a rectifier electrically connected to the pump control unit. The implantable rectifier can convert the AC to DC for powering the pump control unit. The system can include an external controller electrically connected to the rectifier. The external controller can provide AC electrical power to the implantable blood pump.

Abstract: The present invention relates to the composition of a nanoparticle based on a magnesium salt, and methods of drug delivery using the nanoparticle. A preferred embodiment uses magnesium phosphate, with or without a shell to deliver aiRNA and/or siRNA. The nanoparticles of the present invention are also effective when administered orally.

Abstract: A disinfection system is provided herein. The disinfection system includes an UV light source to generate UV light and a housing supporting the UV light source. The housing includes a fan and a shield having a body partially surrounding the UV light source. The body has an inner surface sized and shaped to reflect the UV light from the UV light source. The body defines at least one hole configured to receive air flow from the fan and direct the air flow to contact the UV light source to control a temperature of the UV light source.

Abstract: The invention relates to an electronic smoking device (10) and an additive reservoir (162). In order to be able to supply additive to liquid atomized by the electronic smoking device (10) at the user's choice, the electronic smoking device (10) comprises an additive inlet conduit (44) and the additive reservoir (162) comprises an additive outlet opening (72) that can be brought into communication with the additive inlet conduit (44).

Abstract: The present invention relates to a dinitroxide biradical compound of general formula (I): In formula (I), A is a carbon, an ammonium, or a phosphonium; each of A1 to A6 is a single bond, O, N, N(O), S, S(O), SO2, C(O), or a (C1-C4) alkyl chain; and Z1 and Z2 are selected from R1 and R2 in combination, so that there is always at least one R2 group that is substituted with R3 group. In Z1 and Z2, R1 is an H, an aryl, or a heteroaryl; R2 is an alkyl chain, an alkenyl chain, an alkynyl chain, a cycloalkyl, a heterocycloalkyl, an aryl, or a heteroaryl; and R3 is an alkyl chain, an alkenyl chain, an alkynyl chain, a cycloalkyl, a heterocycloalkyl, an aryl, a heteroaryl, an ether, an ester, or an azide. When Z1 and Z2 are combined together with the same carbon atom of the nitroxide ring to which they are bonded, they form a spirocycloalkyl or a spiroheterocycloalkyl, the spirocycloalkyl or the spiroheterocycloalkyl being substituted with R3.

Abstract: The present invention relates to a compound of formula (I): (I) as defined in the description. The present invention also relates to a method for extracting biological membrane-associated membrane proteins, comprising a step of bringing an aqueous solution of biological membrane-associated membrane proteins into contact with at least one compound of the invention. The present invention also relates to a method for stabilizing membrane proteins in solution in an aqueous solution, comprising a step (i) consisting in bringing an aqueous solution of a membrane protein in solution into contact with at least one compound of the invention.

Abstract: A system, method and computer-readable storage devices are for normalizing text for ASR and TTS in a language-neutral way. The system described herein divides Unicode text into meaningful chunks called “atomic tokens.” The atomic tokens strongly correlate to their actual pronunciation, and not to their meaning. The system combines the tokenization with a data-driven classification scheme, followed by class-determined actions to convert text to normalized form. The classification labels are based on pronunciation, unlike alternative approaches that typically employ Named Entity-based categories. Thus, this approach is relatively simple to adapt to new languages. Non-experts can easily annotate training data because the tokens are based on pronunciation alone.

Abstract: In one embodiment, an apparatus and associated method are provided, comprising: at a device having a display and a touch-sensitive surface: displaying a first user interface of a first application on the display; while displaying the first user interface of the first application, detecting a first input by a first contact on the touch-sensitive surface that meets one or more criteria; in response to detecting the first input by the first contact that meets the one or more criteria: in accordance with a determination that the first application is subject to the first contact meeting the one or more criteria, ceasing to display the first user interface of the first application and displaying a respective other user interface on the display; and in accordance with a determination that the first application is not subject to the first contact meeting the one or more criteria, maintaining display of the first user interface of the first application without displaying the respective other user interface.

Abstract: A research, analysis, regulatory compliance and media platform that connects customers to finished research and analysis produced by subject matter experts is described. The platform facilitates research, investigations, and analysis by creating a single environment in which a group of distributed analysts conduct research and investigations, store and retrieve documents and other sources, collaborate, and publish findings. Consumers are able to query a published knowledge graph, surface high value relationships, and access insights captured by analyst through a customer web portal or external production environment. The platform allows analysts and customers to research and map the commercial, financial, and facilitation networks of sanctioned or other actors that may be associated with illicit activity. Customers can access visual graphs depicting relationships between sanctioned and non-sanctioned actors in order to evaluate their possible exposure to financial crime or sanctions-related risks.

Abstract: The present invention provides a curable adhesive composition comprising at least one curable silylated polymer and at least one curing catalyst obtained by reaction of a metal alkoxide and an oxime. The present invention also provides the use of a metal compound obtained by reaction of a metal alkoxide and an oxime as curing catalyst for silylated polymers.

Abstract: This invention relates to a process for the preparation of Form B of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide. Also disclosed herein is Form B of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide, or pharmaceutical compositions thereof, obtainable by the process described herein.

Abstract: At least some embodiments of the disclosure may advantageously limit bleeding and the occurrence of blood leaks after heart pump implantation. In some embodiments, a base may be provided that includes a flexible layer mechanically coupled with a conduit. The flexible layer may be coupled with the proximal end of the conduit. The conduit may be configured to receive a cannula of the heart pump therethrough. The outer surface of the conduit may be configured to engage a surface of the heart formed after coring the heart. The conduit may be metal and may have a flared and/or beveled distal end. The conduit may be a flexible material. A distal flexible layer may be provided at a distal end of the conduit that is configured to engage with an inner surface of the heart.

Abstract: A method and system for matching an unknown facial image of an individual with an image of a celebrity using facial recognition techniques and human perception is disclosed herein. The invention provides a internet hosted system to find, compare, contrast and identify similar characteristics among two or more individuals using a digital camera, cellular telephone camera, wireless device for the purpose of returning information regarding similar faces to the user. The system features classification of unknown facial images from a variety of internet accessible sources, including mobile phones, wireless camera-enabled devices, images obtained from digital cameras or scanners that are uploaded from PCs, third-party applications and databases. Once classified, the matching person's name, image and associated meta-data is sent back to the user. The method and system uses human perception techniques to weight the feature vectors.

Abstract: A coding distortion removing method is provided for removing coding distortion in two adjacent blocks located on both sides of a block boundary between the two adjacent blocks in a reconstructed image. The method includes deriving a difference of pixel values between a pixel in a first block of the reconstructed image and a pixel in a second block of the reconstructed image adjacent to the first block, deriving an average value of the first quantization parameter and the second quantization parameter, and setting a threshold value to the average value of the first quantization parameter and the second quantization parameter. The method also includes comparing the difference of pixel values with the threshold value, and removing a coding distortion in an area disposed on both sides of the block boundary between the first block and the second block, by applying a filter for coding distortion removal.

Abstract: A method for detecting and quantifying additives in a complex aqueous fluid, and a method for detecting an inhibitor of mineral deposition or corrosion, injected in a gas or oil well. The invention also relates to a developer solution including a lanthanide and a chelating agent for detecting said additives or inhibitors.

Abstract: The aim of the present invention is to provide a method capable of producing an optically active pyrimidinamide derivative on an industrial scale. Compound (I) or a salt thereof is subjected to an asymmetric reduction reaction, the obtained compound (II) or a salt thereof is subjected to a deprotection reaction, and the obtained compound (III) or a salt thereof is reacted with compound (VI) or a salt thereof to obtain compound (V) or a salt thereof. wherein each symbol is as defined in the specification.