Abstract: Orally available compounds, a process for preparing the same and their uses as anti-adhesive drugs for treating E. coli induced inflammatory bowel diseases such as crohn's disease.
Type:
Grant
Filed:
January 23, 2015
Date of Patent:
November 26, 2019
Assignees:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE D'AUVERGNE, UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE 1, UNIVERSITE DE NANTES, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
Abstract: A method is provided for producing data representing radiotherapy treatment constraints associated with a patient to be treated. The method includes: a phase of mapping at least one current atlas of a set of atlases according to at least one datum representing a patient to be treated, providing a map of probability regions at risk; and a phase of generating at least one datum representing a constraint to be applied to a treatment for the patient according to the probability of regions at risk.
Type:
Grant
Filed:
April 18, 2014
Date of Patent:
November 26, 2019
Assignee:
UNIVERSITE DE RENNES 1
Inventors:
Oscar Acosta, Gael Drean, Renaud De Crevoisier, Pascal Haigron
Abstract: A cam phaser for a cam shaft arrangement including an inner cam shaft and an outer cam shaft arranged concentrical relative to the inner cam shaft, the cam phaser including at least one rotor; at least one stator; and at least one compensation element configured to compensate axial and/or radial and/or angular tolerances, wherein the stator is connectable torque proof at least indirectly through a drive gear with the outer cam shaft and the rotor is connectable torque proof with the inner cam shaft, wherein the drive gear is separate from the stator and attachable torque proof at the outer cam shaft, wherein the stator is rotatably supportable on the inner cam shaft, wherein plural compensation elements are provided which are arranged evenly distributed in a circumferential direction, wherein the compensation elements are configured torsion stiff in the circumferential direction and attached between the stator and the drive gear.
Type:
Grant
Filed:
February 24, 2018
Date of Patent:
November 26, 2019
Assignee:
ECO Holding 1 GmbH
Inventors:
Andreas Berwinkl, Rene Heym, Markus Todt, Stephan Wanner
Abstract: Method for generating a shear wave in a target region of a soft solid, includes the following steps: a) generating at least two shear waves with a first and a second source of shear waves in the target region; b) detecting a propagation pattern of the shear wave in the target region with a detector unit including a row of ultrasonic transducers aligned on a first direction perpendicular to a detection direction of each or a single ultrasonic transducer movable along a first direction perpendicular to its detection direction; c) proceeding to a time reversal of the detected propagation pattern; and d) submitting the target region to an inverted excitation set of forces based on the temporally inverted propagation pattern. During step b), a first propagation pattern is detected when only the first source is active and a second propagation pattern is detected when only the second source is active.
Type:
Grant
Filed:
February 26, 2015
Date of Patent:
November 26, 2019
Assignees:
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), Université Claude Bernard Lyon 1, Centre Léon-Bérard
Inventors:
Stefan Catheline, Remi Souchon, Ali Zorgani, Jean-Yves Chapelon
Abstract: A chemical impairment detection system adaptable for use in a vehicle. The impairment detection system includes an intake adapted to receive an air sample from a source and an alcohol sensor for detecting an alcohol level in the air sample. An integrated breath chamber channels the air sample from the intake to the alcohol sensor. Source evaluator means in the breath chamber measure one or more characteristics of the received air sample for validating the sample. The source evaluator means measures the air sample characteristics as the air sample flows through the breath chamber.
Type:
Grant
Filed:
December 17, 2015
Date of Patent:
November 26, 2019
Assignee:
#1 A LifeSafer, Inc.
Inventors:
Nicholas M. Trainor, Louis Urani, James Hu, Jeffrey Vatter, Scott A. Galvin, David Hamo, William H. Collins, James Dunn
Abstract: Techniques for mounting a sensor are disclosed. In some implementations, a molded interconnect device carries a sensor for transducing a position of a rotor of the implantable blood pump. The molded interconnect device includes one or more integrated electronic circuit traces configured to electrically connect the Hall sensor with a printed circuit board of the implantable blood pump, and the molded interconnect device is configured to be mounted to the printed circuit board.
Abstract: Techniques are disclosed for visually conveying a percept. The percept may represent information learned by a video surveillance system. A request may be received to view a percept for a specified scene. The percept may have been derived from data streams generated from a sequence of video frames depicting the specified scene captured by a video camera. A visual representation of the percept may be generated. A user interface may be configured to display the visual representation of the percept and to allow a user to view and/or modify metadata attributes with the percept. For example, the user may label a percept and set events matching the percept to always (or never) result in alert being generated for users of the video surveillance system.
Type:
Grant
Filed:
July 22, 2014
Date of Patent:
November 26, 2019
Assignee:
AVIGILON PATENT HOLDING 1 CORPORATION
Inventors:
Wesley Kenneth Cobb, Bobby Ernest Blythe, Rajkiran Kumar Gottumukkal, Ming-Jung Seow
Abstract: This invention relates to a process for the preparation of Form A of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide. Also disclosed herein is Form A of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide, or pharmaceutical compositions thereof, obtainable by the process described herein.
Type:
Application
Filed:
July 13, 2017
Publication date:
November 21, 2019
Applicant:
MEREO BIOPHARMA 1 LIMITED
Inventors:
Osama SULEIMAN, Lucia Romero PEREZ, Cornelius Stephan HARLACHER, Stewart JONES
Abstract: Disclosed is a LED light assembly that accommodates series connected surface mounted LEDs. An LED lighting source comprising surface mounted LEDs can be inserted and removed from a socket to allow replacement of burned out LEDs. The LED lighting source contains all of the components for controlling the intensity and color of the emitted light. In addition, the electrical components may receive control signals to control the output of the surface mounted LEDs. Connectors disposed in a socket are made of spring steel that causes the connectors to contact each other when the LED lighting source becomes loose from the socket or is removed.
Abstract: A solvent transfer printing method for applying a pattern made of a non-soluble material and non-dispersible on the surface of an object. The method includes the steps of: m1/ forming a pattern on a surface of a solvent-soluble substrate, m2/ depositing the solvent-soluble substrate on the surface of a solvent bath, on the side of the substrate opposed to the side on which the pattern is applied, in order to dissolve partially the substrate, m3/ dipping the object in the bath, so that the surface of the object comes into contact with the pattern, m4/ getting the object, on which the pattern is applied, out of the bath, and m5/ drying the object.
Type:
Application
Filed:
January 26, 2018
Publication date:
November 21, 2019
Applicants:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS -, UNIVERSITE DE RENNES 1
Inventors:
Maxime HARNOIS, Jacques EMMANUEL, Brice LE BORGNE
Abstract: An atomizing electronic cigarette has an atomizing core component and a liquid storage component. including an electric heater. The electric heater may have a through hole aligned with a channel passing through the liquid storage component. The cigarette can heat and uniformly vaporize liquid from the liquid storage component, with the user inhaling the vaporized liquid. The vapor generated by the atomizing process may be cooled as it flows through the channel.
Abstract: A control method for an apparatus for ultrasonically measuring the flow rate of a fluid in a measuring channel, including a measuring channel whose one end is equipped with a first transducer and the other end is equipped with a second transducer, each transducer emitting ultrasonic waves to the other transducer, and receiving waves generated by the other transducer, where, in a first step, the first transducer emits waves to the second transducer, and in a second step, which can be simultaneous with the first one, the second transducer emits waves prior to the reception of the waves emitted by the first transducer.
Type:
Grant
Filed:
April 10, 2018
Date of Patent:
November 19, 2019
Assignees:
EFS SA, ECOLE CENTRALE DE LYON, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLAUDE BERNARD LYON 1, INSTITUT NATIONAL des SCIENCES APPLIQUEES DE LYON
Abstract: A modular building unit for construction of a building comprises a structural frame 40 suitable for interconnection to another modular building unit in construction of the building; and a stud frame wall 80/82 internal to and fixed to the frame. The modular building unit is suitable for handling as a shipping container for transport.
Abstract: A cam phaser including a stator that is driven by a crank shaft of an internal combustion engine; and a rotor that is connectable torque proof with a cam shaft of the internal combustion engine and that includes plural blades that protrude radially outward from a rotor hub, wherein operating chambers arranged between the stator and the rotor are divided into pressure cavities by the blades, wherein the stator and the rotor are configured as sintered components, wherein displacement recesses are provided on axially configured faces of the stator and/or of the rotor wherein material is configured to flow into the displacement recesses during a deforming finishing of the faces.
Type:
Grant
Filed:
January 8, 2018
Date of Patent:
November 19, 2019
Assignee:
ECO Holding 1 GmbH
Inventors:
Markus Heilig, Florian Hentsch, Dietmar Schulze
Abstract: Blood pump devices having one or more sensors for monitoring performance of a bearing assembly and/or a fluid-tight seal are provided herein. Such devices are particularly useful in blood pump devices that have cantilevered rotors supported by a sealed mechanical bearing disposed outside a blood flow path of the device to avoid thrombus formation caused by blood contact with the bearing. The one or more sensors can include one or more accelerometers adapted to detect movement of the bearing assembly along one or more axes during operation of the pump. A vibration profile can be determined from the movement data from the one or more sensors that is indicative of performance of the bearing assembly and/or seal so as to allow monitoring over time.
Abstract: Novel hybrid nanoparticles, useful for inhibiting or slowing down the formation of sulfur deposits or minerals in a well during the extraction of gas or oil. Specifically, the nanoparticles each include (i) a polyorganosiloxane (POS) matrix; and, optionally as a coating over a lanthanide oxide core, (iii) at least one polymeric scale inhibitor during the extraction of gas or oil. The invention also relates to the method for obtaining the nano-inhibitors and the application of same.
Type:
Grant
Filed:
December 15, 2014
Date of Patent:
November 12, 2019
Assignees:
TOTAL SA, UNIVERSITE CLAUDE BERNARD LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
Inventors:
Christian Hurtevent, Salima Baraka-Lokmane, John-Richard Ordonez-Varela, Olivier Tillement, Arthur Marais, Albert Moussaron
Abstract: An active implantable medical device comprising a therapeutic device, a controller and at least one rechargeable battery, wherein a single hermetically sealed housing encapsulates a therapeutic device, controller and rechargeable battery. A hermetically sealed housing additionally encapsulates a wireless interface and a commutator.
Abstract: Embodiments of the present invention include enhanced functionalities and components within a Communication Endpoint Processor (CEP) that act as an interface between computational and communications domains. The embodiments disclosed herein deliver a complete memory mapped high performance interface that has the ability to support the simultaneous transmission of multiple frames of multiple sizes, and that has the ability to interrupt the transmission of lower priority frames in order to send higher priority frames.