Patents Assigned to 1
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Patent number: 10266821Abstract: The present invention provides asymmetrical duplex RNA molecules that are capable of effecting sequence-specific gene silencing. The RNA molecule comprises a first strand and a second strand. The first strand is longer than the second strand. The RNA molecule comprises a double-stranded region formed by the first strand and the second strand, and two ends independently selected from the group consisting of 5?-overhang, 3?-overhang, and blunt end. The RNA molecules of the present invention can be used as research tools and/or therapeutics.Type: GrantFiled: March 25, 2016Date of Patent: April 23, 2019Assignee: 1GLOBE HEALTH INSTITUTE LLCInventors: Chiang Jia Li, Xiangao Sun, Harry Rogoff, Youzhi Li
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Patent number: 10266584Abstract: The present invention relates to antibodies or fragments thereof that specifically bind to glycoprotein (GP) of Ebola virus, and to their use for treating and diagnosing Ebola virus disease.Type: GrantFiled: February 8, 2016Date of Patent: April 23, 2019Assignees: INSERM (Institut National de la Sante et de la Recherche Medicale), Université Claude Bernard—Lyon 1, ENS—Ecole Normale Superieure de Lyon, Centre National de la Recherche Scientifique (CNRS)Inventors: Olivier Reynard, Viktor Volchkov
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Patent number: 10265450Abstract: Disclosed are systems for wireless energy transfer including transcutaneous energy transfer. Embodiments are disclosed for electrical connections between an implanted wireless receiver and an implanted medical device powered by the receiver. Methods for manufacturing and using the devices and system are also disclosed.Type: GrantFiled: January 18, 2017Date of Patent: April 23, 2019Assignee: TC1 LLCInventors: David Eldridge, Joseph C. Stark, III, Andrew MacDonell, Scott Kramer, Thomas George Kilavos, Fabian Frigon Franco
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Patent number: 10266474Abstract: The present invention relates to the use of molybdenum and vanadium mixed oxides, optionally iron doped, as catalysts for the oxidation of unsaturated alcohols, in particular allyl alcohol, and also to a process for the production of unsaturated carboxylic acids, in particular acrylic acid, in the gas phase, in the presence of such a catalyst.Type: GrantFiled: June 18, 2015Date of Patent: April 23, 2019Assignees: Centre National De La Recherche Scientifique, Universite Des Sciences et Technologies De Lille 1, Hokkaido University, Ecole Centrale De LilleInventors: Sébastien Paul, Benjamin Katryniok, Franck Dumeignil, Marcia Araque Marin, Toru Murayama, Wataru Ueda
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Patent number: 10265447Abstract: Disclosed herein is a method of pumping blood in a patient. The method includes inserting an impeller housing and impeller into the patient, the impeller disposed within the impeller housing and having a longitudinal axis, positioning the impeller housing and the impeller at a treatment location in the patient, activating an adjustment device at a proximal end portion of the heart pump outside the patient to provide relative motion between the impeller housing and the impeller along the longitudinal axis, and pumping blood through the impeller housing along the longitudinal axis.Type: GrantFiled: June 15, 2017Date of Patent: April 23, 2019Assignees: TC1 LLC, The Penn State Research FoundationInventors: Robert L. Campbell, Jeremy J. Koncoski, Thomas M. Mallison, Mark W. McBride, Daniel Metrey, Eric C. Myer, Kevin J. Powell, Adam Roslund, Daniel A. Walters, William James Repka, Phyllis Yuen
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Patent number: 10262209Abstract: The invention provides a method of analyzing video data comprising the steps of recording the video data using one or more video recording devices; analyzing at least one video frame of the video data to extract identification information regarding a specific object of interest that is comprised in a watch list of a plurality of objects of interest, the watch list including at least one entry for each of the plurality of objects of interest; computing a matching value by comparing the extracted identification information with predetermined identification information of the specific object of interest; and storing object data and the matching value as an additional entry in the watch list in association with the specific object of interest.Type: GrantFiled: May 18, 2017Date of Patent: April 16, 2019Assignee: L-1 IDENTITY SOLUTIONS AGInventors: Martin Werner, Brian Scott Swann
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Publication number: 20190105012Abstract: A first embodiment comprises a stethoscope with a body; a diaphragm; and an integral annular axially compliant suspension. The annular axially compliant suspension is located below the diaphragm and inside an inner perimeter of the body. Optionally, an axially compliant reticulated foam pressure pad is located within the annular suspension, and the diaphragm is a very thin foil, preferably made from copper, to provide antimicrobial properties. In a second embodiment, a stethoscope with a body and a diaphragm having a flexible enclosure containing an incompressible liquid suspended in the stethoscope body and a reticulated foam pressure pad below the diaphragm and within the body is disclosed. Optionally, the diaphragm has a cap over a top end of the suspended flexible enclosure, preferably made from copper to provide antimicrobial properties.Type: ApplicationFiled: October 5, 2018Publication date: April 11, 2019Applicant: INGEN1, LLCInventors: Carla W. Falkner, Deneen T. Plessala, Clifford A. Henricksen
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Patent number: 10252909Abstract: The present invention relates to a method for dry reforming of at least one alkane carried out in at least one reaction chamber, preferably with a catalytic bed, having a stream of gas passing through same. According to the invention, said at least one reaction chamber comprises a catalytic solid which is cyclically and alternatively exposed to a stream of at least one alkane and a stream containing carbon dioxide, such that said catalytic solid is used as an oxidation vector.Type: GrantFiled: April 27, 2015Date of Patent: April 9, 2019Assignees: Universite Des Sciences et Technologies De Lille 1, Centre National De La Recherche Scientifique (C.N.R.S.)Inventors: Axel Lofberg, Louise Duhamel Jalowiecki, Jesus Guerrero
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Patent number: 10257600Abstract: An earphone includes a housing having a sound output hole, wherein a center axis line of the sound output hole is deviated from a center axis line of the housing by an angle; a drive unit received inside the housing; and a resilient element disposed on the housing, wherein the resilient element can be squeezed and deformed, the resilient element or the housing abuts a cavum conchae of a user.Type: GrantFiled: May 11, 2016Date of Patent: April 9, 2019Assignee: 1MORE INC.Inventors: Kuan-Hong Hsieh, Yonghui Hu, Qianlong Liu
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Patent number: 10251987Abstract: An improved wireless transmission system for transferring power over a distance. The system includes a transmitter generating a magnetic field and a receiver for inducing a voltage in response to the magnetic field. In various respects, the receiver is configured to be implanted in a body. The receiver may include a housing enclosing a receiving coil and associated electronic components, a covering around at least a portion of the housing, and at least two wires wrapped around the housing to form a plurality of turns. The covering may be formed of a ferrite material configured to both magnetically shield a respective portion of the internal volume of the housing and redirect incoming magnetic flux from the transmitter to improve efficiency. Methods of use are also provided.Type: GrantFiled: July 29, 2013Date of Patent: April 9, 2019Assignee: TC1 LLCInventor: John Freddy Hansen
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Patent number: 10257822Abstract: In a terminal, a control unit transmits a bundle response signal using a resource in a basic region of an uplink control channel in an uplink unit band of a unit band group when no error is detected in each of a plurality of pieces of downlink data of the unit band group, the uplink control channel in the uplink unit band being associated with a downlink control channel in a basic unit band that is a downlink unit band in which a broadcast channel signal including information relating to the uplink unit band is transmitted, and the control unit transmits the bundle response signal using a resource in an additional region of the uplink control channel when an error is detected in each of the plurality of pieces of downlink data.Type: GrantFiled: June 18, 2018Date of Patent: April 9, 2019Assignee: Godo Kaisha IP Bridge 1Inventors: Seigo Nakao, Daichi Imamura
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Patent number: 10251809Abstract: A device for treating sleep apnea in a patient through stimulation. The device includes a generator configured to produce stimulation pulses, a stimulator that receives the stimulation pulses produced by the generator and delivers stimulation to the patient, and a controller. The controller is configured to determine a sleep state of the patient, adaptively control the generator based on the sleep state where the sleep state includes a plurality of sleep stages, and modulate a stimulation energy of the stimulation pulses produced by the generator based on the sleep stage of the patient.Type: GrantFiled: February 9, 2015Date of Patent: April 9, 2019Assignees: Sorin CRM SAS, INSERM—INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, UNIVERSITÉ DE RENNES 1, UNIVERSITE JOSEPH FOURIER—GRENOBLE 1Inventors: Laurence Graindorge, Amel Amblard, Christine Henry, Marcel Limousin, Laure Duchemin Laporte, Alfredo Hernandez, Jean-Louis Pépin
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Patent number: 10255753Abstract: A method and apparatus for providing hybrid draw poker games to online players, where electronic indications of an initial set of physical cards and electronic indications of a contingent set of physical cards that are dealt by a live dealer at a physical gaming table. The electronic indications of the initial set of physical cards are provided to one or more online players over a network. The gaming server receives an indication from one of the remote players to discard one or more card values associated of the initial set of physical cards. The gaming server then assigns one or more physical cards of the contingent set of physical cards as first replacement cards to the remote player, and then determines a final game value for the remote player based on the initial physical cards not discarded by the first remote player and the one or more first replacement cards.Type: GrantFiled: October 2, 2018Date of Patent: April 9, 2019Assignee: Uplay1Inventor: Bruce Merati
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Patent number: 10245054Abstract: A device for capturing and removing an obstruction in a bodily duct of a patient. The device includes a cylindrical body having a circumference and a longitudinal axis. According to some implementations the cylindrical body is comprised of a plurality of closed cell structures arranged in diagonal rows around the longitudinal axis. At least some of closed cell structures have substantially the same shape and size. According to some implementations at least some of the closed cell structures of substantially the same shape and size occupy a same circumferential location in the cylindrical body and are longitudinally separated from one another by no less than two, three, four or more diagonal rows of closed cell structures. According to other implementations the closed cell structures include diagonally extending struts having at least a curve portion and a straight portion.Type: GrantFiled: September 6, 2018Date of Patent: April 2, 2019Assignee: HIGHWAY 1 MEDICAL, INC.Inventors: Vera Shinsky, Scott D. Wilson
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Patent number: 10245361Abstract: A centrifugal blood pump includes a housing that defines an inlet passage, a chamber, and an outlet passage. The pump includes an impeller rotatably positioned in the chamber to transfer blood from the inlet passage through the chamber and to the outlet passage and magnetic members embedded in the impeller such that the impeller and the magnetic members rotate together within the chamber. The pump includes a motor to control movement of the impeller in the chamber. The motor is adjacent the chamber and separated from the chamber by a partition member. The pump includes an inner annular magnetic member and an outer annular magnetic member embedded in a side of the housing opposite the partition member. A first net magnetic force between the inner annular magnetic member and the magnetic members exhibits greater attraction than a second net magnetic force between the outer annular member and the magnetic members.Type: GrantFiled: February 12, 2016Date of Patent: April 2, 2019Assignee: TC1 LLCInventors: Masamichi Yanai, Jason Nanna
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Patent number: 10250386Abstract: Methods and systems are provided for power management and security for wireless modules in “Machine-to-Machine” communications. A wireless module operating in a wireless network and with access to the Internet can efficiently and securely communicate with a server. The wireless network can be a public land mobile network (PLMN) that supports wireless wide area network technology including 3rd generation (3G) and 4th generation (4G) networks, and future generations as well. The wireless module can (i) utilize sleep and active states to monitor a monitored unit with a sensor and (ii) communicate with wireless network by utilizing a radio. The wireless module can include power control steps to reduce the energy consumed after sending sensor data by minimizing a tail period of a radio resource control (RRC) connected state.Type: GrantFiled: May 7, 2018Date of Patent: April 2, 2019Assignee: Network-1 Technologies, Inc.Inventor: John A. Nix
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Publication number: 20190091203Abstract: This invention relates to a novel dosage regimen for administration of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide or a pharmaceutically acceptable derivative thereof, namely in the treatment of acute exacerbations of inflammatory conditions.Type: ApplicationFiled: March 8, 2016Publication date: March 28, 2019Applicant: MEREO BIOPHARMA 1 LIMITEDInventors: Colin ORFORD, Cyril CLARKE, Colm FARRELL, Jacqueline PARKIN, Stefan DE BUCK
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Publication number: 20190095720Abstract: Provided is a detection method of a detection device. The detection device detects at least one object from an image by using depth information about the image obtained by a camera. The detection device identifies whether said at least one object is a person through three-dimensional (3D) head model matching, which matches a head candidate area of said at least one object with a 3D head model. The detection device calculates a feature for detection of a situation by using said at least one object when it is identified that said at least one object is the person.Type: ApplicationFiled: July 20, 2016Publication date: March 28, 2019Applicant: S-1 CORPORATIONInventors: Jin Sun JU, Hwijun KIM, Hyang Sook CHOI
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Patent number: 10240170Abstract: Provided are CO hydratase and a method for producing formate using the same, and more specifically, to CO hydratase which is a novel enzyme which is produced by linking CO dehydrogenase (CODH) and CO2 reductase and can directly convert CO into formate, and use thereof.Type: GrantFiled: January 5, 2017Date of Patent: March 26, 2019Assignee: C1CHEM CO., LTD.Inventors: Yong Hwan Kim, Kyoungseon Min, Young Joo Yeon, Dae Haeng Cho, Min Gee Jang, Eun-Gyu Choi, Ho Won Hwang
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Patent number: 10240493Abstract: A cam phaser including a rotation phaser and a hydraulic valve hydraulically loading the rotation phaser, wherein the hydraulic valve is connectable torque proof with a cam shaft so that the cam shaft is rotatable, wherein the rotation phaser includes a stator and a rotor configured coaxial with the stator, wherein the rotor is rotatable relative to the stator, wherein the hydraulic valve is configured so that it protrudes at least partially into the rotation phaser, wherein an adapter is provided for a relative axial positioning of the rotor and the stator. According to the invention the adapter is configured for loose mounting in the rotation phaser so that a fixated connection of the adapter in the rotation phaser is provided when the cam shaft is mounted at the hydraulic valve.Type: GrantFiled: January 16, 2017Date of Patent: March 26, 2019Assignee: ECO Holding 1 GmbHInventors: Steve Nance, John Snyder