Abstract: The present invention provides processes for preparing a prostacyclin analogue of Formula (I) or a pharmaceutically acceptable salt thereof, wherein R10 is a linear or branched C1-6 alkyl. The processes of the present invention comprise steps that generate improved yields and fewer byproducts than traditional methods. The processes of the present invention employ reagents (e.g., the oxidizing reagent) that are less toxic that those used in the traditional methods (e.g., oxalyl chloride). Many of the processes of the present invention generate intermediates with improved e.e. and chemical purity; thereby eliminating the need of additional chromatography steps. And, the processes of the present invention are scalable to generate commercial quantities of the final compound.

Abstract: An aircraft includes a cabin wall defining a cabin and a convertible monument in the cabin adjacent the cabin wall. The convertible monument has a plurality of monument walls defining sides, a front and a rear of the monument surrounding a chamber defined by the monument walls. The convertible monument has a closet component positioned in the chamber for supporting non-perishable items in the chamber. The chamber has a convertible area convertible between a cooling compartment and an uncooled compartment. A chiller is positioned in the chamber proximate the convertible area. The chiller is configured to supply cool air to the cooling compartment when operated for cooling perishable items stowed in the cooling compartment. The convertible area is used as an uncooled compartment for stowing non-perishable items when the chiller is inactive.

Abstract: A transmission for a vehicle may include a first planetary gear set, a second planetary gear set, a third, planetary gear set, and a fourth planetary gear set each including three rotary elements, and a plurality of friction members, in which the friction members are connected to at least one or more of the rotary elements of the planetary gear sets and control rotation of the rotary elements.

Abstract: An apparatus a method for generating a traveling path of a vehicle, may include a sensor device mounted in the vehicle and detecting a surrounding environment of the vehicle; and a controller determining a traveling space in which the vehicle is traveled by considering the surrounding environment of the vehicle, and generating the traveling path within the determined traveling space.

Abstract: A method for assessing ergonomics of a human user in an environment is disclosed. The method includes generating a visual skeletal signal by using a visual sensor. The method further includes determining a first posture sample based on the skeletal signal, by using an electronic controller. The posture sample includes skeletal information including one or both of joint information and positioning information. The method further includes comparing the posture sample with an ergonomically ideal posture sample and determining an ergonomic report based on the comparing of the posture sample and the ergonomically ideal posture sample. The method further includes providing the ergonomic report via an output device.

Abstract: The purpose of the present disclosure is to provide a small optical integrator for increasing color mixing property and homogeneity. An optical integrator is provided with a light entrance surface and exit surface (002, 003), and side surfaces (004, 005, 006, 007) that connect the entrance surface and the exit surface, and is internally filled with a light guide material having a refractive index. The light guide material contains scattering particles for scattering light that have a refractive index different from the refractive index of the light guide material. The light that has entered via the entrance surface propagates from the entrance surface side toward the exit surface while being scattered by the scattering particles in the light guide material, wherein part of the scattered light is guided to the exit surface by propagating while being confined, by internal reflection on the side surfaces, in the light detector.

Abstract: A liquid discharging head includes: a nozzle plate having a plurality of nozzles from which liquid is discharged; a channel member including a plurality of individual liquid chambers that lead to the plurality of nozzles, respectively, and including a plurality of circulation channels that lead to the plurality of individual liquid chambers, respectively; and a common liquid chamber member for forming a common liquid chamber that supplies liquid to the plurality of individual liquid chambers and for forming a circulation common liquid chamber that leads to the plurality of circulation channels.

Abstract: A vibratory plow has a lift bracket. The lift bracket couples to an upper link by an upper spring having an upper energy absorptive member. The upper spring and upper energy absorptive member are configured to limit upper link movement relative to the lift bracket in a first direction. The lift bracket is coupled to the upper link by a lower spring having a lower energy absorptive member; the lower spring and lower energy absorptive member are configured to limit upper link movement relative to the lift bracket in a direction opposite the first direction. The upper link is coupled to a shaker box which is attached to a plow blade. The shaker box is configured to travel from a baseline position a first distance greater than two inches in the first direction before the upper spring compresses enough that the upper energy absorptive member dampens shaker box movement.

Abstract: A golf club head, comprising a body having a center of gravity, wherein the body comprises a coordinate system with an x-axis located horizontal to the face, a y-axis located vertical to the face, and a z-axis located through the face; and a weight system configured to adjust the location of the center of gravity of the body, wherein the weight system comprises a plurality of weight channels formed in the body, an elongate adjustable weight configured to selectively reside in each of the plurality of weight channels, wherein the elongate adjustable weight comprises an aperture at a first end of the elongate adjustable weight, and a fastener configured to reside in the aperture and engage the body, wherein the fastener is configured to affix the elongate adjustable weight to the body.

Abstract: A medical device, comprising a hub or housing having a push tab including a main portion extending radially from an upper surface of the hub or housing, and at least one anti-rotation feature for resisting rotation of the hub or housing. A cannula is directly or indirectly connected to the hub or housing. The medical device may be a catheter, the cannula may be a catheter tube, and the hub or housing may be a catheter hub or an introducer needle tip shield for the catheter.

Abstract: An oral care system that includes an oral care implement and a dispenser, an oral care method, and a method of applying an oral care agent to an oral surface. In one embodiment, the invention may be an oral care system including a toothbrush having a handle defining a longitudinal axis and having a proximal end, a distal end, and a cantilevered top portion. The system may also include a dispenser having a longitudinally elongated housing having a distal end with an applicator thereon and an opposite proximal end. There may be a reservoir disposed in the housing for holding an oral care agent. The reservoir can be in fluid communication with the applicator. The dispenser may be removably attached to the cantilevered top portion of the handle of the toothbrush.

Abstract: An organic light-emitting device (100) comprising an anode (103); a cathode (109); a light-emitting layer (107) between the anode and the cathode; a first hole-transporting layer (105A) comprising a first conjugated hole-transporting polymer between the anode and the light-emitting layer; and a second hole-transporting layer (105B) comprising a second conjugated hole-transporting polymer between the first hole-transporting layer and the light-emitting layer, wherein a lowest excited state energy level of the first hole-transporting polymer is lower than the lowest excited state energy of the second hole-transporting polymer.

Abstract: A computer implemented method of secure communication between a virtual machine in a set of virtual machines in a virtualized computing environment and a shared software service over a network, the method comprising: establishing a network connection between the virtual machine and the software service; communicating data between the virtual machine and the software service; and, establishing a tunneling virtual private network (VPN) connection for communication of encrypted network traffic between the virtual machine and the software service, access to the VPN connection being restricted so as to securely separate communication between the virtual machine and the software service from communication occurring with other virtual machines in the set, and wherein data is communicated between the virtual machine and the software service via the VPN connection.

Abstract: The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, Formula (I) wherein L, X, Ra, Rb, R1, R2 and R3 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.

Abstract: There is provided a compound having Formula I In the formula: Ar can be phenyl, biphenyl, or terphenyl, and can optionally have one or more substituents which can be D, alkyl, silyl, deuterated alkyl, or deuterated silyl; R1 can be alkyl, silyl, aryl, heteroaryl, deuterated alkyl, deuterated silyl, deuterated aryl, or deuterated heteroaryl; R2-R11 are the same or different and can be H, D, alkyl, silyl, deuterated alkyl, or deuterated silyl.

Abstract: A method and apparatus for forming a direct current power supply. An apparatus comprises a transformer and a rectifier. The transformer is figured to output a plurality of phase-shifted alternating currents in response to receiving a plurality of alternating currents. The plurality of alternating currents and the plurality of phase-shifted alternating currents form a plurality of input alternating currents that are offset relative to each other by one-twelfth of a cycle in phase. The rectifier is configured to form a direct current power supply having a common mode voltage reduced to zero within selected tolerances in response to receiving the plurality of input alternating currents.

Abstract: An embodiment semiconductor device includes a first conductive feature in a dielectric layer and a second conductive feature over the dielectric layer and electrically connected to the first conductive feature. The second conductive feature includes a dual damascene structure and further includes a top portion within both a line portion and a via portion of the second conductive feature and a bottom portion in the via portion of the second conductive feature. The bottom portion comprises a different conductive material than the top portion, and a thickness of the bottom portion is at least about twenty percent of a total thickness of the via portion of the second conductive feature.

Abstract: In one aspect, an example method involves a computing device accessing first data representing a program schedule of a media program; accessing second data representing closed-captioning text of the media program; making a determination that first text of the program schedule has at least a threshold extent of similarity with second text of the closed-captioning text, where a portion of the media program was recorded proximate a time when a portion of the second data representing the second text of the closed-captioning text was generated; using the first text of the program schedule as a basis to select a portion of the program schedule; and responsive to at least the determination, storing third data indicative of a correlation between the selected portion of the program schedule and the recorded portion of the media program.

Abstract: A voltage reference circuit is provided that includes a first circuit, a second circuit and a third circuit. The first circuit has a first MOS transistor pair and the second circuit has a second MOS transistor pair. The first circuit is configured to provide a first voltage component that changes at a first rate having a first slope as a temperature to which the voltage reference circuit is subjected changes. The second circuit is configured to provide a second voltage component that changes at a second rate having a second slope as the temperature changes. The third circuit is configured to use the first voltage component and the second voltage component to generate the reference voltage component that changes at a fifth rate having a fifth slope as the temperature changes. The fifth slope is substantially equal to zero to promote insensitivity of the reference voltage component to temperature changes.