Abstract: A capsule has a first end to engage with an electronic cigarette device and a second end arranged as a mouthpiece portion having a vapor outlet, a liquid reservoir located towards the first end and configured to store a liquid to be vaporised; a vaporising chamber located towards the second end and having an air inlet and a vapor outlet; a heating element arranged between the liquid reservoir and the vaporising chamber and configured to vaporise liquid received from the liquid reservoir and generate a vapor in the vaporising chamber; and a flow path extending between the vaporising chamber and the mouthpiece to allow the generated vapor to flow from the vaporising chamber to the mouthpiece. The heating element includes: a heating surface exposed to the vaporising chamber, at a first end of the heating element and a capillary element having a capillary surface exposed to the liquid reservoir.

Abstract: An electrostatic discharge protection device is formed using only electrically connected transistors. The transistors include: a first MOS-type transistor forming a clamping circuit coupled between first and second supply nodes; a second MOS-type transistor coupled between the first supply node and a gate terminal of the first MOS-type transistor; and a third MOS-type transistor having a first gate terminal coupled to a gate terminal of the second MOS-type transistor, a second gate terminal coupled to one of the first and second supply nodes, and first and second conduction terminals coupled to the second supply node.

Abstract: The present invention relates to a transfer module (26) for a folder-gluer machine (1), the transfer module comprising a lower conveyor (36) and an upper conveyor (38) adapted to receive a folding box (2) therebetween and to transport the folding box in a direction of transportation (D) towards a downstream-located loading surface (90) in a stacker module. The upper conveyor (36) of the transfer module extends further in the direction of transportation than the lower conveyor (38) and the lower conveyor comprises a first conveyor belt (38a) and second conveyor belt (38b), each having an inlet end (67a, 67b) and an outlet end (65a, 65b), and wherein the outlet ends are displaceable in the direction of transportation.

Abstract: An aerosol generating device configured to generate an aerosol for inhalation by a user includes: a heater configured to heat an aerosol forming fluid to a predetermined temperature; a sensor configured to measure a parameter which is related to the flow rate of the heated aerosol forming fluid; and a controller configured to enable or disable the generation of an aerosol based on the measured parameter.

Abstract: A control device (2) mounted in an opening (20) in a middle (16) and including a support (14) and a rotatable part, which has a shaft (12), a gripping member (4) and a control member (6) forming a rotation sensor (26). The sensor includes a magnetic detector provided inside the watch case in a radial peripheral region of the control member. On a first side of a circular opening (22), the support has a cavity (24) which is open in the axial direction. The cavity is configured to house the control member fixedly mounted on the shaft, such that this control member can be momentarily retracted, at least for the most part, into the cavity following an axial movement of the shaft into a position in which the magnetic detector is mounted inside the watch case.

Abstract: A cartomizer for an aerosol generating device, includes a container for holding at least one reservoir configured to contain a vaporizable material; a vaporizing chamber fluidly connected to a mouth end by a vapor passage; a liquid transport element, extending from inside the at least one reservoir to inside the vaporizing chamber to convey the vaporizable material from the reservoir to the inside of the vaporizing chamber; and an air inlet arranged to supply the vaporizing chamber with air in use; wherein the liquid transport element is separated from at least one part of the at least one reservoir by at least one compartmenting wall arranged for creating at least one chamber, in particular at least one capillary chamber, communicating by a liquid restriction passage formed in the compartmenting wall of the chamber and wherein at least a portion of the liquid transport element extends in the chamber.

Abstract: A cartomizer for an aerosol generating device includes a first end configured to engage with a control and power supply device, and a second end having a vapor outlet; a container for holding a reservoir to contain vaporizable material, and a vaporizing unit including an electrical heating element 21 and a liquid transport element. The liquid transport is arranged to deliver vaporizable material from the least one reservoir to the heating element, a bottom holder and a pair of electrodes held by the bottom holder at the first end of the cartomizer. The electrodes are made of a ferrous or ferro-magnetic material and extend transversally at the bottom holder so that each electrode forms a first portion of contact with an electrical contact of the control and power supply device and a second portion of contact adjacent the first portion of contact to engage with a magnetic element of the power device.

Abstract: A heater device for an electronic cigarette comprises: a heater unit arranged to vaporise a liquid received from a liquid reservoir and generate a vapour; and a vapour flow path extending from the heater unit and arranged to fluidly communicate with a mouthpiece of an electronic cigarette to allow the generated vapour to flow from the heater unit to the mouthpiece. The heater unit comprises a plurality of through-channels arranged to allow the generated vapour to flow from the heater unit to the vapour flow path. The plurality of through-channels comprises at least two primary through-channels and at least two secondary through-channels, where a diameter of a primary through-channel is different than a diameter of a secondary through-channel. The plurality of through-channels are arranged such that the at least two primary through-channels are alternately arranged with the secondary through-channels.

Abstract: An aerosol generating device is described. The aerosol generating device includes a heating chamber comprising an opening arranged to receive a consumable; a heating apparatus for heating the consumable; wherein the heating apparatus comprises two or more heating segments and at least one insulator; 5 the two or more heating segments are arranged longitudinally along a length of the heating chamber and are configured to be independently heated; and the at least one insulator is arranged between adjacent heating segments. In this way, the device is capable of efficiently heating consumables of different shapes and sizes.

Abstract: A method and a device for probing a subsurface structure. The method includes sending an electromagnetic wave into the structure, receiving an echo of the electromagnetic wave from the structure and processing the echo for deriving an internal feature of the structure. The sending the electromagnetic wave into the structure includes subsequently sending a plurality of electromagnetic probe signals with differing frequency spectra into the structure. Each probe signal includes at least two non-zero spectral components. The receiving the echo includes receiving an echo signal for each probe signal. The processing the echo includes determining at least one amplitude and phase for each echo signal.

Abstract: A method for treating and/or preventing polycystic ovary syndrome (PCOS) including the administration, to a patient in need thereof, of a pharmaceutically effective amount of a compound of Formula I or a pharmaceutically acceptable solvate thereof.

Abstract: The present invention relates to methods of treating or preventing AIBD.

Abstract: Systems, methods, and computer program products for smart upload automation in which actions are automatically performed on a set of digital assets against a target item. In one embodiment, a system includes a network, a server machine, a client machine and a data storage device, each of which is coupled to the network. The client machine designates digital assets and a target item against which the assets will be uploaded. The digital assets are uploaded by the client machine to the data storage device via the network. The server machine automatically performs actions on the digital assets without intervention by the client machine, where the actions are associated with or in some way defined by the target item. The actions may include setting metadata values of the digital assets based upon metadata associated with the target item, or generating different renditions of the digital assets.

Abstract: A device for storing and extending a hose for supplying conditioned air to an aircraft on the ground or to any other interior space, includes: a tubular housing (11) extending along a longitudinal axis (Z) and having a free open first end, which tubular housing (11) can store a hose; a hose (1) in fluid communication with a conditioned air unit and having a free downstream end; a drive system (4) that can be used to control the extension and retraction of the hose (1) between a retracted position in which the downstream end of the hose (1) is located in the tubular housing (11), and an extended configuration in which the downstream end of the hose (1) is outside the tubular housing (11) and at a distance from the first end of the tubular housing (11). The drive system (4) has N=4 to 8 drive bearings (6.1-6.6) disposed perpendicularly to the longitudinal axis (Z) and connected to one another by N swivel joints (7.1-7.7), thereby forming a closed chain.

Abstract: Systems and methods for assessing PPG signals generated based on transdermal optical data can include a computing device generating a color intensity signal using an acquired sequence of transdermal images of a subject. The computing device can compute a signal quality metric of the color intensity signal. The computing device can provide an indication of a quality of the color intensity signal for display on a display device associated with the computing device. The indication of the quality of the color intensity signal can be determined based on the signal quality metric.

Abstract: A rubber compound for the production of tire portions comprising a polymer base with a cross-linkable unsaturated chain, a filler system and a vulcanization system. The filler system comprises (a) a quantity, greater than or equal to 25 phr, of a first carbon black having a surface area smaller than or equal to 170 m2/gr; (b) a second carbon black having a surface area greater than or equal to 300 m2/gr in a quantity that is such that the ratio between the quantity of said first carbon black and the quantity of said second carbon black is greater than or equal to 5 and smaller than or equal to 13; (c) a quantity ranging between 0.5 and 2.0 phr of a dispersant agent comprised in the class of aromatic amides and having an unsaturation suited to interact with the polymer base with a cross-linkable unsaturated chain.

Abstract: RNA encoding an immunogen is delivered in a liposome for the purposes of immunisation. The liposome includes lipids which have a pKa in the range of 5.0 to 7.6 and, preferably, a tertiary amine. These liposomes can have essentially neutral surface charge at physiological pH and are effective for immunisation.

Abstract: A medical fluid delivery system includes a source of purified water; a source of concentrate for mixing with water from the water source; a disposable set including a pumping portion, a water line in fluid communication with the source of purified water and the pumping portion, the water line including a filter for filtering the water, a concentrate line in fluid communication with the concentrate source and the pumping portion, and a heater/mixing container in fluid communication with the pumping portion; a medical fluid delivery machine including, a pump actuator operable with the pumping portion of the disposable set, and a heater/mixing pan configured to support the heater/mixing container; and at least one leveling foot positioned and arranged to enable the heater/mixing pan to be oriented in a desired position for mixing the concentrate and purified water. A leveling tray and leveling foot are provided additionally.

Abstract: A timepiece mechanism (100) for disengaging a gear train. The timepiece mechanism (100) includes a gear set (110), a disengagement member (120), a holding member (121) and a control member (130). The gear set (110) includes a first wheel (111), a second wheel (112) and an intermediate wheel (113) configured to be driven by or for driving the first wheel (111) and/or for driving the second wheel (112). The holding member (121) holds the first wheel (111) and/or the second wheel (112) when the disengagement member (120), controlled by the control member (130), moves the intermediate wheel (113) between an engaged position (101) and a disengaged position (102). Hence the timepiece mechanism (100) is held in position while disengaging the watch mechanism.

Abstract: Compounds of formula (I), wherein A, R, L, Z, Q1, Q2 and n have the meaning according to the claims, can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease.