Abstract: A strip assembly helically windable to form a pipe is disclosed. The strip assembly includes a pair of joined elongate strips, each strip having a strip width and a strip height and each strip including: a base; at least one longitudinal rib upstanding from the base; a pair of spaced apart longitudinal parallel edges; and an angled joining end surface. Each joining end surface has a joining width, the joining width at least 5% greater than the strip width. Also each joining end surface has a joining height, the joining height at least 10% greater than the strip height. The additional joint area provided by the angled joining end surfaces provides a significantly stronger joint.

Abstract: A mining machine frame having a primary tow plate is disclosed, as well as a tow retrieval system for mounting to the primary tow plate of a mining machine frame. The tow retrieval system may include a brake release mounting plate configured for attachment to the primary tow plate of the mining machine frame. The tow retrieval system may also include a towing attachment also configured for attachment to the primary tow plate of the mining machine frame. The towing attachment may be further configured to receive a retrieval instrument during a towing operation.

Abstract: The invention provides a method of reducing the propensity of a diesel fuel composition to take up zinc when exposed to zinc during storage and/or transportation, the method comprising formulating a diesel fuel composition to be stored or transported in contact with zinc such that said diesel fuel composition has an aniline point greater than 80° C.

Abstract: A gaming machine is disclosed that provides a game in which a player of the gaming machine stakes a wager on one or more outcomes of the game that are represented as symbols arranged in an array of symbol display positions. The player controls the number of outcomes on which a wager is staked by operating a user interface. During play of the game the gaming machine causes a display to display indicia representative of the total number of outcomes selected but not display indicia representative of every available outcome and not display indicia of every selected outcome. Indicia representative of an individual outcome is displayed when that outcome defines a winning combination. A method of providing a graphical user interface for a gaming machine is also disclosed.

Abstract: The invention relates to purinergic (P2X) receptors, to generation of antibodies and to use of antibodies and immunogens for detection and treatment of a disease or condition, especially cancer.

Abstract: The invention is a method and composition for treating a topical microbial infection in a subject. The method includes the step of administering a therapeutically effective amount of a polyether ionophore, or a therapeutically acceptable salt thereof, to the subject.

Abstract: The invention is directed to a push opener for bottles. The push opener includes a mechanism configured to remove a bottle cap when the opener is introduced over a bottle and pushed downwardly, and trigger a promotional or entertainment action.

Abstract: There is provided a contact lens (60) which is produced by cast molding. The cast molding is achieved by the use of an anterior face mold insert (30) which has a cap (24) with a domed surface (26) and a body (10). The domed surface has provision for a distance vision segment (31) and a reading segment (32) separated by a demarcation (33). Further, the cap (24) has a cutaway portion (20) for producing a lower ledge and the body (10) has a projection (18) for producing a lower truncation in the resultant lens. Means is also described for forming a posterior face of the contact lens (60).

Abstract: A closed-loop hydraulic apparatus 200 for converting wave energy comprises a pump 201 for pumping a fluid through the apparatus 200. The pump 201 includes a body 202 defining a chamber 203, and a piston 207 that partitions the chamber 203 into a working side 208 and a blind side 209. A buoyant actuator is connected to the piston 207. An inlet 64 is connected to the working side 208 of the chamber 203 so that the fluid is able to flow from the inlet 64 and into the working side 208 of the chamber 203. An outlet 63 is connected to the working side 208 of the chamber 203 so that the fluid is able to flow from the working side 208 of the chamber 203 to the outlet 63. A hydraulic controller 102 is operable to control the pump 201 by controlling the pressure of the fluid at the inlet 64 and the outlet 63 so as to optimise the output of the pump 201 in response to tidal variations and/or sea state. The pressure of the fluid at the inlet 64 and the outlet 63 is controlled in accordance with a control algorithm.

Abstract: The present invention relates to a structure and a container for culturing cells. In one arrangement, the structure (200) comprises a partially enclosed cavity (204) and a plurality of compartments (201) adapted for fluid communication with the partially enclosed cavity (204). Each compartment (201) is configured to hold one or more cell within its compartment (201) at a location dependent on a dimension of the cell. This arrangement may facilitate visual identification or indication of the size of the cell by observing its location within its compartment (201). The structure (200) may be included or formed integrally with a container (100) such as a Petri dish.

Abstract: The present disclosure provides compositions and methods for the prevention or treatment of ocular neovascularization, such as AMD, in a human subject, by administering subretinally a pharmaceutical composition comprising a pharmaceutically effective amount of a vector comprising a nucleic acid encoding soluble Fms-related tyrosine kinase-1 (sFlt-1) protein to the human subject.

Abstract: The invention relates generally to methods for the production of biofuels from organic matter, the methods comprising treating the organic matter with an aqueous solvent and at least one additional catalyst under conditions of heat and pressure. The invention also relates to biofuel products obtainable by the methods.

Abstract: A swiveling joint for use in a pole such as a light pole is disclosed. The swiveling joint connects a first member mounted to a lower leg of a pole with a second member mounted to an upper leg of the pole. The second leg has a skirt which sits around an annular portion of the first member, with a bearing member located between the first and second members. The bearing member can be moved from outside the second member between a locked position where the joint is fixed, and a released position where the joint can rotate.

Abstract: A direct evaporative cooler includes a liquid delivery system and an assembly of two or more plates. At least one plate of the assembly of two or more plates may include a top surface having a wicking material with an exposed surface for receiving a liquid thereon from the liquid delivery system, and one or more masks lining a portion of the exposed surface. The one or more masks may be impermeable to the liquid thereby preventing the liquid from evaporating through the one or more masks, and the one or more masks may be sized and shaped such that a wick rate of the liquid on the exposed surface exceeds an evaporation rate of the liquid.

Abstract: A system, and method, for managing recreational vehicle a central control unit (A) at a convenient facility and a unit (B) installable on a vehicle, with each unit (A) and (B) operable to receive data from and to send data to the other. Unit (A) includes a rules database module for holding an organised, searchable list of a rules database for control and management of a vehicle 12 on which a unit (B) is installed to comprise an on-vehicle unit B. The unit (A) also includes a rules engine module operable to receive, and compare with the rules list of database, data from the second unit (B). The unit (B) includes a location tracking module and a sensor data module, with the location tracking module adapted to track the position of the vehicle in real time by obtaining vehicle positional data, while the sensor data module is operable to collect data from at least one sensor of the vehicle and to pass the data to the unit (A).

Abstract: The present invention relates generally to nucleic acid molecules, the RNA and protein expression profiles of which are indicative of the onset, predisposition to the onset and/or progression of a neoplasm. More particularly, the present invention is directed to nucleic acid molecules, the expression profiles of which are indicative of the onset and/or progression of a large intestine neoplasm, such as an adenoma or an adenocarcinoma. The expression profiles of the present invention are useful in a range of applications including, but not limited to, those relating to the diagnosis and/or monitoring of colorectal neoplasms, such as colorectal adenocarcinomas. Accordingly, in a related aspect the present invention is directed to a method of screening a subject for the onset, predisposition to the onset and/or progression of a neoplasm by screening for modulation in the expression profile of one or more nucleic acid molecule markers.

Abstract: This disclosure provides intact bacterially derived minicells containing nucleic acids adjuvants or plasmids encoding nucleic acids adjuvants that can produce a desired immune response in target cells. This disclosure further provides methods that employ minicells to deliver nucleic acids adjuvants for use in the treatment of diseases, including neoplastic disease and cancer.