Abstract: An endoscope having a handle including a frame, a fluid handling device secured to the frame via an interface, the fluid handling device comprising a fluid passage having a first fluid opening, a tube in fluid communication with the fluid opening of the fluid handling device, and shell parts enclosing a cavity accommodating the frame, the tube, and at least partly the fluid handling device therein, wherein, at least prior to enclosing the frame, the tube, and at least partly the fluid handling device within the cavity of the shell parts, the interface and the tube are configured to permit movement of the fluid handling device relative to the frame within a pre-determined boundary comprising a first position and a second position separated by a distance.

Abstract: An endoscope handle for an endoscope for visually inspecting inaccessible places, such as human body cavities, the endoscope handle including: a frame (70) having a first wall portion (101) formed as an integral portion of the frame, the frame being formed as a single component; a liquid-tight chamber (100) accommodating a circuit (25), preferably a printed circuit board, of the endoscope handle, wherein the liquid-tight chamber is at least partly defined by the first wall portion of the frame; and a first shell part (60) and a second shell part (60?) together enclosing a cavity (63), the shell parts accommodating and securing the frame within the cavity, the shell parts forming an exterior surface (68) shaped to form an ergonomic grip for an operator, wherein the shell parts and the frame each are formed as separate components.

Abstract: An ostomy appliance has an adhesive wafer with a backing layer and an adhesive layer attached to the backing layer. The adhesive wafer has sensing means capable of recording application of pressure to the adhesive wafer during application of the ostomy appliance to the skin.

Abstract: The present invention relates to a stopper for an injector for delivery of a pharmaceutical composition and to an injector with the stopper. The stopper has a stopper body with an actuating surface opposite an outlet surface, an axial length between the actuating surface and the outlet surface, and a transverse diameter, which stopper body defines an access diameter, the stopper at an axial location from the actuating surface comprising a deformable sealing element surrounding the stopper body and having an outer diameter, which is larger than the transverse diameter, which deformable sealing element is made from a thermoplastic elastomer and has an axial extension in the range of 5% and 95% of the axial length of the stopper body, and the stopper comprising a cavity at the axial location of the deformable sealing element, the cavity having a lateral extension larger than the access diameter of the stopper body.

Abstract: A liquid supply system includes a suction lance (6) configured to be inserted into a liquid container (14) and at least one level sensor (10, 12) fixed on the lance (6) and configured to detect a liquid level (22) inside a liquid container (14). A control device (4) is connected to the level sensor (10, 12) and configured to determine a rate of change of the liquid level (22) detected by the at least one level sensor (10, 12) and to detect a lance removal if the rate of change reaches or exceeds a predefined threshold. A method for detecting the removal of a suction lance (6) from a liquid container (14) is provided.

Abstract: Disclosed are variants of a cellulase having improved stability in the presence of a protease, and the use of such variants in laundry.

Abstract: The present invention relates to a wind turbine rotor blade assembly comprising a rotor blade and a noise reducer (70) configured on the rotor blade. The noise reducer (70) comprises a plurality of aligned spine members (72), each spine member having a length and comprising a first section (74) extending along a first part of the length of the spine member, and a second section (76) extending along a second part of the length of the spine member, wherein the first section (74) has a higher stiffness than the second section (76).

Abstract: The present disclosure relates to a hearing aid and detachable speaker unit assembly. The detachable speaker unit assembly comprises a fastening structure to provide an enhanced removal force and stable insertion into the ear canal of the user.

Abstract: A hollow core photonic crystal fiber (PCF) including an outer cladding region and seven hollow tubes surrounded by the outer cladding region. Each of the hollow tubes is fused to the outer cladding to form a ring defining an inner cladding region and a hollow core region surrounded by the inner cladding region. The hollow tubes are not touching each other, but are arranged with distance to adjacent hollow tubes. The hollow tubes each have an average outer diameter d2 and an average inner diameter d1, wherein d1/d2 is equal to or larger than about 0.8, such as equal to or larger than about 0.85, such as equal to or larger than about 0.9. Also, a laser system.

Abstract: A wind turbine control unit includes an upsampling module that receives a first control signal that includes a current control sample value and a predicted control trajectory. The upsampling module also calculates a second control signal in dependence on the current control sample value and the predicted control trajectory. The second control signal has a higher frequency than the first control signal. The upsampling module further outputs the second control signal for controlling an actuator.

Abstract: A method of producing a case hardened workpiece of a Group IV metal including: placing a workpiece of a Group IV metal in a vessel, creating a low pressure environment in the vessel in which the pressure, pvac, is less than or equal to 10-5 bar, providing oxygen to the vessel to create a reactive atmosphere in the vessel, the reactive atmosphere comprising oxygen at a partial pressure, pO2, in the range of 10 5 bar to 0.01 bar, heating the workpiece to a hardening temperature in the range of 650° C. to 800° C. in the reactive atmosphere or before the reactive atmosphere is created, maintaining the workpiece in the reactive atmosphere at the hardening temperature for a reactive period of at least 5 hours, cooling the workpiece from the hardening temperature to ambient temperature in the reactive atmosphere or in an inert atmosphere.

Abstract: An unwrapping apparatus, configured to unwrap a stack of wrapped articles, including an unwrapper head, which includes a housing, a cutter head, a drive, wherein the drive is configured to rotate the cutter head relative to the housing. The cutter head includes a gripper, a knife, and an actuator, configured to move the gripper along a path of movement relative to the housing, between a retracted position and an advanced position. The unwrapping apparatus further including a robotic manipulator arm, configured to move the unwrapper head, a registration device, configured to register a contour of the stack, and a controller, configured to control the robotic manipulator arm and the drive, in accordance with the registered contour.

Abstract: An optical fiber having an axial direction and a cross section perpendicular to the axial direction, and a method and preform for producing such an optical fiber. The optical fiber is adapted to guide light at a wavelength ?, and includes a core region, an inner cladding region surrounding said core region, and at least one of a first type of feature including a void and a surrounding first silica material. The core, the inner cladding region and the first type of feature extends along said axial direction over at least a part of the length of the optical fiber. The first silica material has a first chlorine concentration of about 300 ppm or less.

Abstract: The present invention relates to prodrugs of 4-((1R,3S)-6-cloro-3-phenyl-2,3-dihydro-1H-inden-1-yl)-1,2,2-trimethylpiperazine in the form of 1a and 1b; and 4-((1R,3S)-6-chloro-3-(phenyl-d5)-2,3-dihydro-1H-inden-1-yl)-2,2?-dimethyl-1-(methyl-d3)piperazine in the form of 2a and 2b, wherein X? is a counter ion, or pharmaceutically acceptable salts thereof. The present invention also provides pharmaceutical composition comprising prodrugs, or pharmaceutically acceptable salts thereof, of the invention.

Abstract: The present invention relates to compositions such as cleaning compositions comprising a mix of enzymes. The invention further relates to use of compositions comprising such enzymes in cleaning processes.

Abstract: A method for preparing a sample of organic material for laser induced breakdown spectroscopy (LIBS) may include obtaining granular organic material, forming a portion of the granular organic material into a sample pellet, and searing the organic material. The searing may include searing only an exposed end surface of the sample pellet on which LIBS analysis is to be performed. The method may include pressing the seared sample pellet to consolidate the material comprising the seared end surface.

Abstract: Compositions comprising L-arginine and L-citrulline in specific ratios are provided. Use of such compositions for improving sexual function in a healthy human subject are also provided.

Abstract: An apparatus and process for distillation of methanol which may also be used in distillation of other products, such as ethanol. The apparatus and process have the purpose of reducing the consumption of energy and of cooling water and/or electricity in a distillation process of crude intermediate products, including a pre-treatment stage, known as stabilizing stage, for the removal of the volatile components, and a concentration stage, including one or more columns for distillation.

Abstract: The present invention relates to xylanase variants, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; compositions comprising the xylanase variants and methods of using the variants.

Abstract: A handle (4) for an endoscope (1) includes a first shell-shaped (6) housing part and a second shell shaped housing part (7) adapted for mutual engagement so as to form a housing. The shell-shaped housing parts (6, 7) include a first recess (10) and a second recess (11) so arranged and configured that when the first and second shell-shaped housing parts (6, 7) are mutually engaged, a circumferential recess is provided in the exterior surface of the housing. The handle (4) further includes a hoop (28) adapted to be received in the circumferential recess and hold the first and second shell-shaped housing parts together.