Patents Assigned to ACell, Inc.
  • PARTICULATE TISSUE GRAFT WITH COMPONENTS OF DIFFERING DENSITY AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20150265748
    Abstract: Disclosed are tissue graft compositions made of particles having different densities, methods of making these compositions, and methods of using these compositions for promoting tissue restoration in a patient.
    Type: Application
    Filed: May 14, 2015
    Publication date: September 24, 2015
    Applicant: ACell, Inc.
    Inventors: Rodney W. Bosley, JR., Clay Fette, Robert S. Tullius
  • Methods of manufacturing bioactive gels from extracellular matrix material
    Patent number: 9119831
    Abstract: The present invention is directed to methods of manufacturing bioactive gels from ECM material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue engineering and regenerative medicine approaches to tissue reconstruction. The manufacturing methods take advantage of a new recognition that bioactive gels from ECM material can be created by digesting particularized ECM material in an alkaline environment and neutralizing to provide bioactive gels.
    Type: Grant
    Filed: July 16, 2014
    Date of Patent: September 1, 2015
    Assignee: ACell, Inc.
    Inventors: Kimberly A. Kentner, Katherine A. Stuart, Abram D. Janis
  • Particulate tissue graft with components of differing density and methods of making and using the same
    Patent number: 9056078
    Abstract: Disclosed are tissue graft compositions made of particles having different densities, methods of making these compositions, and methods of using these compositions for promoting tissue restoration in a patient.
    Type: Grant
    Filed: January 24, 2014
    Date of Patent: June 16, 2015
    Assignee: ACell, Inc.
    Inventors: Rodney W. Bosley, Jr., Clay Fette, Robert S. Tullius
  • Hemostatic device
    Patent number: 8975075
    Abstract: A hemostatic device, method of making, and method of using for internal and external applications to wounds in the body of a patient to induce hemostasis at an anatomical site.
    Type: Grant
    Filed: October 7, 2014
    Date of Patent: March 10, 2015
    Assignee: ACell, Inc.
    Inventors: Clay Fette, Abram Janis, Benjamin Kibalo
  • Particulate tissue graft with components of differing density and methods of making and using the same
    Patent number: 8968761
    Abstract: Disclosed are tissue graft compositions made of particles having different densities, methods of making these compositions, and methods of using these compositions for promoting tissue restoration in a patient.
    Type: Grant
    Filed: November 20, 2012
    Date of Patent: March 3, 2015
    Assignee: ACell, Inc.
    Inventors: Rodney W. Bosley, Jr., Clay Fette, Robert S. Tullius
  • Variable density tissue graft composition and methods of making and using the same
    Patent number: 8962035
    Abstract: Disclosed are tissue graft compositions made of materials having different densities, methods of making, and methods of treatment for restoring tissues in a patient.
    Type: Grant
    Filed: September 19, 2013
    Date of Patent: February 24, 2015
    Assignee: ACell, Inc.
    Inventors: Rodney W. Bosley, Jr., Clay Fette
  • Hemostatic device
    Patent number: 8895304
    Abstract: A hemostatic device, method of making, and method of using for internal and external applications to wounds in the body of a patient to induce hemostasis at an anatomical site.
    Type: Grant
    Filed: December 6, 2012
    Date of Patent: November 25, 2014
    Assignee: ACell, Inc.
    Inventors: Clay Fette, Abram Janis, Benjamin Kibalo
  • Hemostatic device
    Patent number: 8835174
    Abstract: A hemostatic device, method of making, and method of using for internal and external applications to wounds in the body of a patient to induce hemostasis at an anatomical site.
    Type: Grant
    Filed: January 23, 2014
    Date of Patent: September 16, 2014
    Assignee: ACell, Inc.
    Inventors: Clay Fette, Abram Janis, Benjamin Kibalo
  • Methods of manufacturing bioactive gels from extracellular matrix material
    Patent number: 8802436
    Abstract: The present invention is directed to methods of manufacturing bioactive gels from ECM material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue engineering and regenerative medicine approaches to tissue reconstruction. The manufacturing methods take advantage of a new recognition that bioactive gels from ECM material can be created by digesting particularized ECM material in an alkaline environment and neutralizing to provide bioactive gels.
    Type: Grant
    Filed: February 7, 2014
    Date of Patent: August 12, 2014
    Assignee: ACell, Inc.
    Inventors: Kimberly A. Kentner, Katherine A. Stuart, Abram D. Janis
  • Particulate tissue graft with components of differing density and methods of making and using the same
    Patent number: 8652500
    Abstract: Disclosed are tissue graft compositions made of particles having different densities, methods of making these compositions, and methods of using these compositions for promoting tissue restoration in a patient.
    Type: Grant
    Filed: July 22, 2009
    Date of Patent: February 18, 2014
    Assignee: Acell, Inc.
    Inventors: Rodney W. Bosley, Jr., Clay Fette, Robert S. Tullius
  • Tissue graft composition
    Patent number: 8541032
    Abstract: Disclosed are tissue graft compositions made of materials having different densities, methods of making, and methods of treatment for restoring tissues in a patient.
    Type: Grant
    Filed: October 11, 2012
    Date of Patent: September 24, 2013
    Assignee: ACell, Inc.
    Inventor: Miles Grody
  • Conditioned decellularized native tissues for tissue restoration
    Patent number: 8409625
    Abstract: The invention provides a composition conditioned for the remodeling, restoration, repair, or replacement of tissue within a host. The composition is conditioned by culturing cells on the matrix and/or by exposing the cultured cells or matrix to one or more stressors.
    Type: Grant
    Filed: January 9, 2009
    Date of Patent: April 2, 2013
    Assignee: ACell, Inc.
    Inventor: Stephen F. Badylak
  • Variable density tissue graft composition
    Patent number: 8298586
    Abstract: Disclosed are tissue graft compositions made of materials having different densities, methods of making, and methods of treatment for restoring tissues in a patient.
    Type: Grant
    Filed: July 22, 2009
    Date of Patent: October 30, 2012
    Assignee: Acell Inc
    Inventors: Rodney W. Bosley, Jr., Clay Fette
  • Tissue regenerative composition, method of making, and method of use thereof
    Patent number: 6893666
    Abstract: A matrix, including epithelial basement membrane, for inducing repair of mammalian tissue defects and in vitro cell propagation derived from epithelial tissues of a warm-blooded vertebrate.
    Type: Grant
    Filed: October 25, 2002
    Date of Patent: May 17, 2005
    Assignee: ACell, Inc.
    Inventor: Alan R. Spievack
  • Tissue regenerative composition, method of making, and method of use thereof
    Patent number: 6890562
    Abstract: A matrix, including epithelial basement membrane, for inducing repair of mammalian tissue defects and in vitro cell propagation derived from epithelial tissues of a warm-blooded vertebrate.
    Type: Grant
    Filed: October 25, 2002
    Date of Patent: May 10, 2005
    Assignee: ACell, Inc.
    Inventor: Alan R. Spievack
  • Tissue regenerative composition, method of making, and method of use thereof
    Patent number: 6890564
    Abstract: A matrix, including epithelial basement membrane, for inducing repair of mammalian tissue defects and in vitro cell propagation derived from epithelial tissues of a warm-blooded vertebrate.
    Type: Grant
    Filed: October 25, 2002
    Date of Patent: May 10, 2005
    Assignee: ACell, Inc.
    Inventor: Alan R. Spievack
  • Tissue regenerative composition, method of making, and method of use thereof
    Patent number: 6890563
    Abstract: A matrix, including epithelial basement membrane, for inducing repair of mammalian tissue defects and in vitro cell propagation derived from epithelial tissues of a warm-blooded vertebrate.
    Type: Grant
    Filed: October 25, 2002
    Date of Patent: May 10, 2005
    Assignee: ACell, Inc.
    Inventor: Alan R. Spievack
  • Tissue regenerative composition, method of making, and method of use thereof
    Patent number: 6887495
    Abstract: A matrix, including epithelial basement membrane, for inducing repair of mammalian tissue defects and in vitro cell propagation derived from epithelial tissues of a warm-blooded vertebrate.
    Type: Grant
    Filed: October 25, 2002
    Date of Patent: May 3, 2005
    Assignee: ACell, Inc.
    Inventor: Alan R. Spievack
  • Tissue regenerative composition, method of making, and method of use thereof
    Patent number: 6869619
    Abstract: A matrix, including epithelial basement membrane, for inducing repair of cmammalian tissue defects and in vitro cell propagation derived from epithelial tissues of a warm-blooded vertebrate.
    Type: Grant
    Filed: October 25, 2002
    Date of Patent: March 22, 2005
    Assignee: ACell, Inc.
    Inventor: Alan R. Spievack
  • Tissue regenerative composition, method of making, and method of use thereof
    Patent number: 6861074
    Abstract: A matrix, including epithelial basement membrane, for inducing repair of mammalian tissue defects and in vitro cell propagation derived from epithelial tissues of a warm-blooded vertebrate.
    Type: Grant
    Filed: October 25, 2002
    Date of Patent: March 1, 2005
    Assignee: ACell, Inc.
    Inventor: Alan R. Spievack